NYU researchers have identified new predictors for Alzheimer's disease, including brain atrophy and biomarkers in cerebrospinal fluid. These findings may help predict individuals at high risk of developing the disease, enabling early detection and prevention.
Researchers found that individuals with a maternal history of Alzheimer's disease exhibit progressive metabolic reductions in glucose usage, particularly in areas of the brain affected by AD. This study bolsters previous findings and suggests that maternal risk for AD may be mediated through reduced brain metabolism.
Researchers at NYU Langone Medical Center presented several key findings on Alzheimer's disease risk factors, including a study that identified signs of brain pathology in healthy individuals. They also reported promising results from couples counseling and antibody tests against common mouth bacteria linked to Alzheimer's disease. The...
Scientists at NYU Langone Medical Center have identified a new cellular pathway that responds to DNA damage and is linked to the development of cancer. The pathway involves a process that targets proteins for disposal, which could potentially be used to sensitize cancer cells to treatment.
Researchers at NYU Langone Health identified a class of custom-made immune cells called regulatory T cells that prevent allergic reactions by recognizing potential allergens. These cells are produced in response to a gene called Foxp3 and help control damage from long-term inflammation.
A new study led by NYU Langone Medical Center researchers found that children who carry Helicobacter pylori are nearly 59% less likely to have asthma. The bacteria, which has co-existed with humans for at least 50,000 years, may strengthen the immune system and reduce the risk of allergic reactions.
Researchers develop a biomarker to detect pleural mesothelioma through plasma osteopontin levels. NYU Cancer Institute also explores using microRNAs to discover novel biomarkers and presents a new strategy for restoring androgen sensitivity in prostate cancer, as well as a potential melanoma vaccine
A new study reveals that the ancient protein Rho serves a regulatory function in E. coli, maintaining boundaries between genes and silencing toxic foreign DNA acquired through gene swapping. This finding provides insights into bacterial genome organization and suggests potential applications in antibiotic development.
Infants in low socio-economic households exposed to TV have limited verbal interactions with their mothers, a new study found. Educational programming can increase interactions when co-viewed by both mother and infant.
Larger skin lesions are more likely to be melanomas than smaller moles, according to a new study by NYU researchers. The study confirms that an important warning sign of melanoma - moles larger than 6 millimeters - is still valid.
A new study reveals that children with a mild form of alpha thalassemia have more red blood cells, which provides an advantage against life-threatening malarial anemia. This adaptation allows them to tolerate massive blood cell loss during severe malaria attacks.
Researchers have discovered a potential therapeutic approach to prevent the accumulation of toxic protein plaques in the brain, which are a hallmark of Alzheimer's disease. The study suggests that binding cystatin C to soluble amyloid beta prevents its aggregation into insoluble plaques.
Locally advanced breast cancer (LABC) may account for 50% of breast cancers in developing countries and 30% among socially disadvantaged women. A new study identifies a molecular switch essential for LABC development, which could be targeted for new therapies.
A recent study found that individuals with an affected mother have reduced brain metabolism in certain regions, similar to Alzheimer's patients. This suggests a possible link between maternal transmission and increased disease risk.
A new mathematical model explains how persistent microbes co-exist with humans, suggesting an increase in virulent organisms as populations grow. The model proposes that larger populations select for more virulent microbes, leading to potentially severe epidemics.
A new study found that early family intervention can alter children's biological response to stress, leading to improved behavior and reduced risk of delinquency. The intervention, which includes parenting strategies and social skills training, resulted in increased cortisol levels in anticipation of a socially stressful situation.
A new study led by Dr. Mary S. Mittelman found that enhanced counseling and support for Alzheimer's caregivers preserves their physical health and eases depression. The intervention improved self-reported health within four months of enrollment, lasting over a year.
A recent study found that a virulent strain of H. pylori may help protect children from developing asthma, with those carrying the strain being 40% less likely to have had asthma before age 15. The microbe was also associated with protection against ragweed and other allergies in younger adults.
A recent study found that human skin hosts a vast array of bacterial species, with 182 species identified, including 8% previously unknown. The study used advanced molecular methods to analyze skin samples from six healthy individuals and revealed a core set of bacteria present in everyone's skin.
A new study conducted at NYU Medical Center found that lap band surgery is an effective procedure for combating obesity in adolescents. Patients who underwent the surgery lost approximately 50% of their excess weight within a year, with no significant complications.
A new study of over 7,000 Japanese-American men found that those from large families were more than twice as likely to develop stomach cancer due to the bacterium Helicobacter pylori. Younger siblings in these families appeared especially vulnerable to the most common type of stomach cancer.
The scientists' achievement provides new avenues for diagnosing and treating this sexually transmitted disease, affecting an estimated 170 million people worldwide. The genome contains genes and proteins not found in humans, which can help expand drug options and devise a diagnostic test.
Researchers developed a synthetic protein fragment that blocks the interaction between Apo E and amyloid beta, reducing its aggregation by around 50% in mouse brains. The treatment showed no apparent inflammation or memory decline in animal tests.
A new study published in the New England Journal of Medicine found that patients who undergo angioplasty to open their totally blocked coronary arteries days after a heart attack do not reduce their risk of having another heart attack, going into heart failure, or dying. The study, which involved over 2,166 patients on five continents,...
A psychosocial support program for Alzheimer's caregivers has been shown to delay nursing home placement by an average of 1.5 years, according to a long-term study published in Neurology. This delay can result in significant cost savings for families, estimated at over $100,000 annually.
Researchers at NYU Langone Health have unraveled the signals governing ovarian development, revealing a feedback loop that ensures sufficient primordial germ cells in the ovary. This discovery has implications for understanding organ growth, regeneration, and disease treatment using stem cells.
A new study by Dr. Judith S. Hochman's group demonstrates that some patients who quickly received invasive treatment with angioplasty or open-heart surgery to bypass clogged coronary arteries survive long-term, and the superiority of this treatment is sustained over time.
A novel approach to epilepsy surgery in young children with tuberous sclerosis has shown promising results, with 17 of 25 patients freed from seizures after a multi-stage brain operation. The procedure involves multiple surgeries to remove seizure-causing tissue, and may improve developmental outcomes for affected children.
Karen Duff, a young British scientist, received the Potamkin Prize for her innovative work on developing transgenic mouse models of age-related human brain diseases. Her research has led to significant advancements in understanding Alzheimer's disease and identifying potential treatments.
Researchers have discovered a new mechanism that regulates the action of K-Ras, a cellular protein that plays an important role in many human cancers. The study found that phosphorylation of K-Ras weakens electrostatic bonds, allowing it to dislodge from the plasma membrane and promote apoptosis.
A recent investigation by the US Consumer Product Safety Commission found that home paper shredder injuries disproportionately affect young children, with 71% of cases involving kids under 12 years old. The study highlights the dangers of easy access to shredders and lack of safety features, such as on/off switches and release mechanisms.
A study of 208 patients treated at Bellevue Hospital from 1990 to 2003 found that most had minor injuries, but some suffered severe amputations or died. The researchers identified a pattern between economic downturns and increased subway accidents, suggesting that slowing down trains could reduce the severity of injuries.
A new study verifies Namenda's effectiveness in slowing cognitive decline and improving daily activities in patients with severe Alzheimer's disease. The medication maintained its benefits when continued treatment was added to the original 28-week study.
Researchers found that air pollution can cause atherosclerosis, the hardening of arteries, when combined with a high-fat diet. Mice exposed to polluted air developed more plaque and high blood pressure, indicating a clear cause-and-effect relationship between PM2.5 exposure and cardiovascular disease.
A study published in Neurology found that depression and anxiety disorders decreased by over 50% two years after epilepsy surgery. Participants who underwent successful surgery without seizures were more likely to be free from depression and anxiety.
Researchers at NYU Langone Health and University of California, Berkeley, have observed the exchange of information between immune cells that sparks a body-wide response to infection. The study reveals how T cells analyze and react to signals of infection at the immunological synapse.
A new study found that elevated blood levels of osteopontin are associated with asbestos-induced cancers, particularly pleural mesothelioma. The protein's levels can serve as a potential biomarker for early detection and monitoring of individuals at risk due to asbestos exposure.
A new study published in Neurobiology of Aging reveals that a computer analysis of the EEG can accurately predict healthy individuals in their 60s and 70s who will develop dementia over the next 7-10 years. The test was found to be almost 95% accurate in identifying those at risk of cognitive decline.
Researchers found that cells without genetic predisposition have a lower mutation rate in PIG-A gene, ranging from 1 in 3 million to 1 in 300,000. A new test for the mutation rate could identify individuals at high cancer risk and help prevent or treat it.
Researchers identify neuregulin gene as key factor in myelin production, enabling faster neural transmission. The discovery opens possibilities for repairing damaged spinal cords and brain tracts.
Researchers found that sensory deprivation prevented substantial synapse loss in growing mice, contradicting the widely-held notion that brain neurons naturally lose connections as they form new ones. The study's findings suggest a potential link between childhood experiences and long-lasting impacts on brain function.
Chronic wounds like bedsores affect millions in US, causing widespread infections and limb amputations. Researchers found skin cells get stuck in healing process due to overabundance of c-myc, a molecule that suppresses cell migration and causes thickened layers around the wound.
A new computer program, HipMask, uses brain scans to predict future Alzheimer's disease, offering a possible tool for early screening. The technique measures metabolic activity in the hippocampus, which diminishes in size as Alzheimer's progresses.
Researchers at NYU Langone Health have developed the first mucosal prion vaccine that protects mice from developing prion disease by up to 500 days. The vaccine uses proteins found on disease-causing organisms and has shown promising results in preventing the progression of prion diseases.
Scientists discover NKT cells primarily patrol liver blood vessels, showcasing agility and rapid movement. The study reveals surprises about NKT cell behavior, including their ability to survive without the CXCR6 gene.
Researchers expand the ABCD rule to recognize changing characteristics of early melanomas, especially nodular melanomas. The new guideline aims to improve detection and diagnosis of this aggressive form of skin cancer.
A small-scale study of GVG, a drug approved for epilepsy in Mexico, found that it can help patients with methamphetamine and cocaine addiction stay abstinent for up to four weeks without visual side effects. The results are promising, but more large-scale studies are needed to confirm the treatment's efficacy.
A new animal study suggests that antioxidant vitamins may increase the secretion of VLDL in liver cells, leading to higher levels of LDL cholesterol. The study found that vitamins hampered a process in the liver that prevents the production of harmful lipoproteins.
A study published in the American Journal of Psychiatry found that enhanced counseling, including individual and family therapy, reduced symptoms of depression among caregivers of loved ones with Alzheimer's disease. After one year, 29.8% of caregivers in the enhanced group showed significant improvement.
A new study found that children who stayed in the ICU for more than 48 hours after cardiac surgery were at a higher risk of developing post-traumatic stress disorder (PTSD). Five out of 43 children met diagnostic criteria for PTSD, with symptoms including disorganized behavior, nightmares, and concentration problems.