Ancient populations across six regions in the central-eastern Eurasian Steppe shifted their diets in near-perfect synchrony over 4,000 years. The study suggests that climate, mobility, and advances in milling technology drove these dietary transitions.
The discovery of Ganiopteris, a 360-million-year-old seed plant from China, provides clear evidence of the earliest-known leaf-borne ovules. This finding marks a major evolutionary milestone and sheds new light on the origin of Permian glossopterids.
Researchers have developed a directly synthesized p-type PbS QD ink to overcome the bottleneck of large-area film uniformity. The approach enabled broad spectral tunability and dense, crack-free films with reduced thickness variation, leading to improved imaging performance.
Researchers have discovered novel quantum phenomena in twisted graphene, including orbital magnetism, quantum anomalous Hall effect, and unconventional superconductivity. The review highlights the flatband electronic structure of magic-angle bilayer graphene, driving complex behaviors like correlated insulators and topological states.
A comprehensive genomic analysis of idiopathic male infertility has identified specific gene defects tied to assisted reproductive technology (ART) outcomes. The study offers actionable insights for infertile men, guiding testicular sperm retrieval, donor sperm use, or ICSI prognosis.
A recent study reveals that tumor cells undergo profound cellular identity reshaping during metastasis in head and neck squamous cell carcinoma (HNSCC), characterized by 'identity rewriting'. WDR54 is identified as a key epigenetic regulator driving this process, promoting tumor-cell lineage plasticity and metastatic progression.
Researchers developed a skin-worn Janus bioelectrode that uses gradient impedance to suppress electromagnetic interference and maintain signal quality. The electrode achieved high recognition accuracy for human motion states when combined with electromyography and electrocardiography signals.
Researchers found that tumor cells use DDB1 to ubiquitinate PD-L1, allowing it to enter the nucleus and drive immune suppression. A new compound, thalidomide, disrupts this process, restoring sensitivity to immunotherapy in preclinical breast cancer models.
Scientists created thresholdless corner vortex solitons that unify topological corner states and vortex light, enabling stable high-speed data transmission. The new solitons resist signal damage and maintain performance across a broad input power window.
Researchers developed a wearable optoelectronic clip that turns exhaled breath into a clear optical switching signal, enabling touch-free interaction and respiratory health monitoring. The device showed high accuracy in multi-user tests, suggesting its potential for practical applications.
A team identified GABPA as the missing link recruiting Integrator complex to target specific genes. Biochemical and structural analyses confirmed direct interaction between GABPA and Integrator's endonuclease module.
Researchers developed a flexible, battery-free hydrogel bioelectronic patch that wirelessly monitors periodontal inflammation and delivers localized miRNA therapy. The system successfully distinguished MMP-9 levels between healthy volunteers and patients with periodontal disease.
A new study reveals that plants with similar volatile organic compound (VOC) profiles can detect and respond to defense signals from neighboring plants more effectively. This finding offers a potential roadmap for designing more pest-resilient agricultural systems by strategically pairing plant species based on their VOC profiles.
High-resolution Solar Orbiter data detected abundant high-frequency magnetohydrodynamic waves in coronal plumes, with energy contributions similar to those of transverse Alfvénic waves. The findings provide crucial evidence for the role of these waves in coronal heating and solar wind acceleration.
The article highlights the need for AI tools to provide interpretable and reportable results, with a focus on improving turnaround time, diagnostic consistency, and clinical decision-making. While AI is unlikely to replace pathologists, it can help convert tissue morphology into actionable evidence for better patient care
Co-transcriptional splicing plays a critical role in regulating chromatin structure, mRNA maturation, and protein diversity. The review identifies key detection methods, regulatory mechanisms, and therapeutic applications for this process.
Researchers found that smaller crumpled sheets exhibit higher load-bearing capacity than larger ones, with denser internal ridge networks playing a key role. The team identified a universal evolution pathway governing the formation of ridges and junctions under compression.
A novel LFIA based on selenium nanoparticles reveals long-term dynamics of neutralizing antibodies against SARS-CoV-2, showing accelerated antibody decline in patients with neurological and hematological diseases. The detection platform enables automated result readout and scalable monitoring for large populations.
Researchers have discovered that tumor-educated pericytes drive alternative angiogenic pathways, bypassing VEGF inhibition and making them a major contributor to drug resistance. A novel therapeutic strategy targeting both endothelial cells and pericytes has shown superior anti-angiogenic effects in multiple cancer models.
A global assessment found that only 63.3% of lakes worldwide meet good water quality standards, exposing nearly half of the world's population to potential health risks associated with freshwater security. Strong regional disparities were observed, with Europe and North America faring better than Asia, South America, and Africa.
Researchers propose a four-stage pathway to evaluate AI for intracranial aneurysm detection, including lesion-level testing, reader performance evaluation, and surveillance after deployment. The framework aims to assess the tool's net clinical benefit in specific care settings.
A new review proposes a paradigm-shifting framework to address the growing threat of Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP). The framework highlights the importance of considering virulence phenotype over co-detection of resistance genes and virulence markers.
A 16-week personalized exercise intervention improved glycemic regulation, physical fitness and reduced abdominal fat while increasing skeletal muscle mass. Cognitive impairment also showed significant improvements in working memory, perceptual speed and executive function.
A research team has developed a dual-side electrosynthesis strategy to convert plastic and biowaste into succinic acid, a versatile four-carbon platform chemical. The new system achieved an apparent succinic acid yield of 169.1%, exceeding the theoretical limit of conventional single-electrode processes.
A new study reveals that USP22 regulates B-cell activation and differentiation through the CHD4-CD19 axis. Inhibiting USP22 partially reversed B-cell hyperactivation in Kawasaki disease patients.
Researchers at Xi'an Jiaotong University create single-molecule magnetostrictor with temperature-dependent response to magnetic fields. The discovery could broaden applications of single-molecule magnets and enable new technologies.
Researchers found that specific bacterial genera on litchi peel act as a 'freshness clock' predicting fruit freshness with high accuracy. They also isolated a strain that inhibits postharvest pathogens, providing a safe alternative to synthetic fungicides.
A study analyzing Chinese and global soil metagenomes found substantial declines in antimicrobial resistance genes after China implemented its AMR control plan. The research suggests a close association between soil resistomes and antimicrobial use patterns across human and animal sectors.
The discovery of Cygnus X-3 reveals it as the most powerful particle accelerator known to date, producing photons with energies up to 30 PeV. The precise temporal variability and high gamma-ray energies measured by LHAASO confirm its status as a source of cosmic rays.
A comprehensive study maps the global CSDH trial landscape, identifying research hotspots, evidence gaps, and future priorities. The study highlights persistent geographic imbalance, recurrence as a core challenge, and the need for standardized anticoagulation management and MMAE guidelines.
Researchers developed a lean-lithium oxychloride solid electrolyte with high ionic conductivity and tunable properties. The interfacial percolation strategy enabled the creation of a continuous transport network throughout the electrolyte, allowing for efficient lithium-ion migration.
Researchers developed an elastic bevel thermal lamination method that removes interlayer impurities, producing clean interfaces and high-performance 2D device arrays. The method significantly reduces bubbles and wrinkles while maintaining structural integrity.
Researchers have designed a tough, fatigue-resistant, and multifunctional biogel for next-gen wearable electronics. The biogel enables self-powered devices for gesture recognition and robotic hand control with high precision.
A new study reveals sericin is an active conductor that directs the self-assembly of silk fibroin into ordered nanofibrils through liquid-liquid phase separation. This discovery fundamentally revises the textbook view of sericin and its role in natural fibers, opening doors to engineering materials with similar architectures.
Engineers create optimized interfacial energy barrier in NbSe2/WSe2 heterostructure to accelerate charge separation while suppressing dark current. This approach enables high-speed optical imaging with enhanced fidelity, opening a promising route for next-generation optoelectronic devices.
The study introduced an interphase activator strategy that couples both processes through one additive, converting native surface species into a reconstructed interphase and regulating the coordination environment in the polymer phase. The optimized electrolyte delivers high ionic conductivity and stability, making it suitable for soli...
Researchers developed a platform to move Dirac points in momentum space, allowing for free sound steering. Two fully passive devices were built: a scanning topological antenna and an angle-tunable Klein tunneling device.
A novel Ga-assisted epitaxial strategy enhances the interfacial thermal conductance of β-Ga2O3 on diamond, resulting in improved heat dissipation. The interface's ultra-high fracture strength and phonon bridge mechanism contribute to this breakthrough.
Scientists discovered two rotational growth modes: free rotation and restricted rotation, which impact CNT structure and quality. Free rotation allows for high-crystallinity growth, while restricted rotation leads to structural distortions and defects.
Researchers argue that aerial robots should turn language instructions into verifiable measurement queries before flight actions to ensure safety. This framing connects semantic goals to technical constraints important in flight, such as movement feasibility and uncertainty reduction.
Researchers at Westlake University have developed a new membrane material that addresses the major obstacle of membrane degradation in anion exchange membrane water electrolyzers. The poly(aryl methylquinuclidinium) membrane shows high performance under demanding operating conditions, enabling scalable industrial manufacturing.
The paper proposes 'transcending natural evolution' by using technology to augment human abilities, bridging the gap between biological and algorithmic iteration. Recent advances in AI, robotics, and bioelectronics are blurring the lines between digital and embodied intelligence.
A new perovskite detector film has been developed to improve X-ray imaging at lower doses, reducing image noise and preserving fine structural details. The detector's internal uniformity helps suppress noise, making it possible to capture clear images at ultralow doses.
Researchers used sEEG to examine white matter electrophysiological dynamics during working memory. Load modulates tract-specific power and cross-frequency connectivity, with distinct patterns across different brain regions.
Researchers discovered that fructooligosaccharide induces the selective enrichment of Anaerotruncus colihominis, a UA-degrading bacterium, via modulation of the gut microbiota. This interaction alleviates oxidative damage to the kidney and offers a new therapeutic rationale for prebiotic-based management of hyperuricemia
Researchers find that superconducting fluctuations enhance nematicity as temperature decreases, leading to a new understanding of electronic nematicity and its relationship with superconductivity. They also uncover the intertwined nematic and d-wave superconductive order in copper oxide high-temperature superconductors.
Researchers develop a data-driven turbulence model that handles various flow mechanisms without needing manual tuning. The model outperforms existing ones in predictability, generality, and robustness across different flow regimes.
Xinjiang's snowpack serves as a seasonal water reservoir, affecting agriculture and mountain-oasis systems. The region experienced an increase in warm-dry snow droughts after 2000, driven by both warming and precipitation deficits.
A new theoretical framework proposes that the information in the brain may be continuously stored, flowed and evolved through dynamic electrophysiological activity generated by spatio-temporal coordinated neural ensembles. The study found that neuronal populations can generate rich electrophysiological activities with periodic features...
A research team developed a walking-support robot that uses large-area tactile contact at the torso to track movement intent and share load. The system continuously adapts as the coupled human-robot dynamics evolve, allowing intention alignment and balance support to emerge from the same physical channel.