Researchers developed an AI-powered framework to optimize 2D material growth, enabling rapid process optimization and customized synthesis. The approach integrated machine learning and knowledge-driven reasoning to decipher multifactorial mechanisms.
Scientists create FeSn-DSACs catalyst to reduce chloride corrosion in seawater batteries, improving oxygen reduction and stability. The p-d orbital hybrid catalyst achieves a half-wave potential of 0.900 V and demonstrates near four-electron ORR pathway.
At an oxide interface, an electric field can shift the main constraint on superconductivity from collective coordination to pair formation, enabling island network formation. This discovery was made at a LaAlO3/KTaO3 interface, where superconductivity is confined to a thin layer.
Researchers created a photocatalyst that uses natural seawater to achieve high solar-to-hydrogen efficiency, with chlorine ions playing a key role in boosting charge separation and reaction kinetics. The system produced hydrogen selectively from water oxidation, with no byproducts, and showed dynamic solar-responsive behavior.
Researchers developed a perovskite/silicon tandem solar cell with a record voltage of 2.014V and 34% efficiency. The nano-scaffold innovation uses zirconia nanoparticles to improve perovskite growth and suppress interface recombination.
Global mortality and disability-adjusted life-year (DALY) burdens increased from 1990 to 2021, with neurological disorders showing the largest increase in mortality rates. Non-communicable diseases, particularly cardiovascular diseases, dominated DALY rates, while population growth and ageing contributed to changing disease burdens.
Thermochromic smart windows reduce energy use and improve comfort by regulating temperature and solar heat. The technology has limitations, including material stability and climate dependence, but has potential for climate-resilient buildings.
The study reveals that compressive strain and oxygen content drive a microscopic evolution towards superconductivity in Ruddlesden-Popper nickelates. Electronic states associated with interlayer orbitals become delocalized, long-range magnetic order loses coherence, and robust short-range magnetic correlations persist.
Researchers found that PGK1 restricts viral replication by targeting a host chaperone required by multiple viruses, such as IAV, SeV, VSV, and HSV-1. This study expands the biological functions of a classic metabolic enzyme and reveals a link between cellular metabolism and antiviral defense.
Researchers developed a chirality-engineered ruthenium nanozyme that protects against chemotherapy-induced cardiotoxicity by modulating the gut-heart axis. The nanozyme restored gut microbial homeostasis and host metabolism, reducing oxidative stress and inflammation, while maintaining anticancer efficacy.
A new gel electrolyte helps zinc iodine batteries operate in a wide temperature range, from -40 to 90°C. The electrolyte design regulates water activity and stabilizes both electrodes, improving battery durability and performance.
Super-resolution microscopy is transforming the field of molecular imaging by enabling researchers to measure molecular organization and behavior with increased accuracy. Advances in artificial intelligence, fluorescent probes, and image analysis are making nanoscale imaging faster, deeper, and more reliable.
Researchers developed a high-entropy sulfide catalyst that preserves its structure and suppresses atomic migration, enabling high sulfur utilization and conversion efficiency. The study proposes a failure-mechanism-guided approach to catalyst design, pointing to unresolved questions in all-solid-state sulfur chemistry.
The cGAS-STING pathway connects cellular aging to brain inflammation, with self-DNA accumulating in the cytoplasm and triggering chronic inflammation. Mitochondrial DNA plays a key role in this process, linking metabolic dysfunction to glial activation and neuronal damage.
A research team integrated deep drilling, geophysical surveys, and 3D geological modeling to study Jiaodong's gold deposits. They found that fault-dip inflections and gently dipping faults control the spatial distribution of gold orebodies, refining the step-wise mineralization model for hydrothermal vein-type gold deposits.
New study defines thermodynamic-dynamic synergy metric to capture WPSH's linkage to East Asian weather anomalies. The JPDF metric shows stronger correlations with precipitation and temperature anomalies, projecting robust increases in WPSH area and intensity under future warming.
Researchers developed a multi-level dynamic integrated perception network to address temporal variability in cross-time EEG emotion recognition. The model achieves high accuracy and selectively calibrates temporal variability to preserve stable emotional signals.
Researchers have developed a diamond material that actively regulates fractures by dissipating energy at the crack tip, leading to enhanced hardness and crack resistance. The material, NPD8, combines high hardness with increased indentation fracture toughness, making it suitable for high-speed cutting and drilling applications.
Researchers develop a new approach combining probiotics with T cells to improve tumor localization and coordination of local immune responses. The therapy, called T-FOLactis, shows improved tumor control and median survival in mouse colorectal cancer models.
A team of researchers used low-temperature STM to investigate image potential states on Bi(111), a material with higher-order topological character. They observed a strikingly unexpected splitting feature, which they propose is related to a monopole-like topological magnetoelectric response.
A study found that a bacterial enzyme BvDPP4, produced by gut microbes, weakens a protective intestinal signal GLP-2, aggravating colitis in a preclinical model. Inhibiting BvDPP4 with theaflavin improved colitis symptoms.
A comprehensive review maps the RNA regulatory landscape in plants, detailing the biological functions and regulatory mechanisms of diverse plant RNAs. The review highlights the latest research breakthroughs in hot areas such as non-coding RNAs, RNA epigenetic regulation, and RNA chemical modifications.
Researchers developed an automated method to convert standard eye scans into an objective cataract biomarker. The method, tested on 1906 eyes, demonstrated exceptional diagnostic discrimination and strong correlation with a standard cataract grading system.
A new review in Science Bulletin outlines how multimodal AI can integrate molecular, cellular, and clinical data to refine treatment choices and predict side effects. The approach aims to address challenges in cancer treatment, including primary resistance and immune-related adverse events.
A research team developed a scalable bilayer roofing membrane that maintains its reflective properties during long-term use, reducing energy consumption. The membrane achieved a solar reflectance of 94.1% and improved upon surface contamination, allowing it to preserve its cooling effect for extended periods.
The FAST All Sky HI Survey has detected 156,411 extragalactic HI sources, nearly four times the previous record, and achieved a median sensitivity of 0.57 mJy/beam. The survey provides a high-quality dataset for galaxy evolution studies in the SKA era.
Researchers developed a biodegradable metal-polymer composite stent that outperforms traditional stents in a 5-year clinical trial involving 1,108 patients. The stent's polymer coating reduces inhomogeneity of degradation but increases corrosion rate, leading to faster degradation and later device fracture.
Researchers have successfully produced ultrathin sodium niobate sheets using a novel molecular-sieve-assisted method, enabling UV detection, imaging and two-wavelength information encoding. The sheets achieved high responsivity and external quantum efficiency, and demonstrated stable operation over 3,800 cycles.
Researchers developed a highly durable electrocatalyst for seawater oxidation using high-entropy selenide materials with integrated dual-protection mechanisms. The catalyst sustained over 1000 hours of stable oxygen evolution with excellent catalytic kinetics and selectivity.
Researchers developed a kinetic method to assemble 2D organic crystals into vertical heterostructures, achieving a high vertical epitaxy yield of over 70%. The resulting structures exhibit tunable light emission due to the unique twist angle and lattice matching between the crystals.
Researchers from Shanxi University and Nanjing University demonstrate two-mode squeezed light in the audio-frequency band on a chip, achieving quantum entanglement between generated optical modes. The system enables stable quadrature measurements across multiple frequency channels, paving the way for future chip-scale quantum sensors a...
A new fabrication strategy called Mix-ice lithography enables direct construction of nanoporous carbon structures with tunable pores and complex geometries. The technique achieves simultaneous control over nanoscale patterning and pore formation without chemical developers or thermal pyrolysis.
A new strategy has been developed to help macrophages stay active inside tumors. Tiny patches are attached to macrophages, which break down and release zinc ions to activate the immune system. This approach combines immune-cell reprogramming with tumor-environment remodeling, helping macrophages regain anti-tumor activity.
Researchers developed WiFo-2, a generalist wireless foundation model that learns reusable channel state information representations and transfers them across scenarios, system configurations, and tasks. The model achieved state-of-the-art performance on 9 communications and sensing tasks with only 1% labeled data.
A study in mice and humans reveals that high estrogen levels disrupt a specific neural circuit from the lateral hypothalamus to the hippocampus, causing temporary memory impairment. This finding provides a biological basis for the phenomenon of 'pregnancy brain' or 'mom brain'.
A Phase 3 trial found that oral edaravone improved functional recovery in AIS patients who did not receive reperfusion therapy, with 65.4% achieving a modified Rankin Scale score of 0-1 at 90 days. The treatment was safe and showed consistent benefits across predefined subgroups, supporting the neuroprotective properties of edaravone.
A symmetry-engineered b-As/2H-TMDs heterostructure distinguishes photocurrent generation along different crystal directions. The device generates photocurrent at zero bias in the armchair direction but not in the zigzag direction, enabling polarization-sensitive performance and applications in integrated photonics and optical sensing.
Researchers created 5-nanometer-thick hafnia-based ferroelectric films with strong polarization and stability at 225 °C. The improved grain structure reduces defect accumulation, leading to reliable operation and high-temperature reliability.
A 'warm-west/cold-east' North Pacific sea surface temperature dipole signals the start of high-skill forecasting periods for East Asian winter cold surges. Forecasts that account for matching SST anomalies in key regions reach 100% accuracy rates during La Niña conditions.
Research reveals two distinct types of Indian Ocean Dipole with different physical mechanisms and climate impacts. The west-east type IOD shows a stronger connection with East African autumn rainfall, while the central-east type IOD has a weaker influence.
A new study estimates that Parkinson's disease could cause a cumulative macroeconomic loss of CNY 473 billion between 2020 and 2040. The disease affects China's economy by reducing labor force participation, productivity, and investment in education and infrastructure.
mRNA-LNPs are shifting the paradigm of drug delivery, enabling vaccines, personalized cancer vaccines, and in vivo gene editing. CAR-engineered cells can be directly generated in vivo, offering a streamlined alternative to ex vivo CAR-T manufacturing.
Engineered microbe-based micro/nanorobots can revolutionize clinical intervention for luminal cancers by navigating and adapting to hostile luminal cavities. The review categorizes this living robotic paradigm into four synergistic capabilities, including active navigation, environmental sensing, and continuous biosynthesis.
A new review in Medicine Plus traces the development of deep brain stimulation, mapping mechanisms and clinical targets across 16 disorders. It highlights future personalized strategies and calls for validated biomarkers and standardized reporting.
Researchers have identified genetic hotspots and real-world adoption gaps in developing green and efficient maize varieties. These varieties have been shown to increase global yields by 10.1% and improve nitrogen utilization efficiency by 16.7%, while reducing reactive nitrogen losses by 26.6%. However, realizing the full potential of ...
Researchers developed a portable AI-assisted microfluidic platform to detect sub-resistant bacteria, combining machine learning with the ancient 'six-four water diversion' principle. The platform provides a more refined view of bacterial drug response and can identify sub-resistant populations that conventional tests may overlook.
A modular nano-adaptor approach tunes T-cell activation to control CD3 activation and prevent toxicity, increasing therapeutic effectiveness in solid tumors. The platform has identified promising lead designs for multispecific nanoantibody configurations.
A new adaptive computing architecture is developed to improve forecasting of chaotic systems, such as weather patterns and ocean currents. The system uses a reconfigurable memristor array to change its physical connections, achieving improved accuracy over fixed-topology reservoir hardware.
The PAN2-PAN3 complex initiates mRNA degradation in early embryo development by trimming long poly(A) tails. Its deficiency causes transcript clearance failure, leading to developmental toxicity.
A study finds that younger cohorts and regions with lower economic development will experience higher lifetime heatwave exposure under climate change. Climate change is widening inequalities between generations and regions, with younger people facing more frequent and intense heat extremes.