Researchers discovered a massive expansion of the HK gene family in thermophilic snails, which can survive temperatures exceeding 55 °C. This expansion led to the emergence of membrane-localized HKs, enhancing hexose catabolism and ATP production.
A new study assesses the long-term effects of China's Shan-Shui Initiative, finding that vegetation greenness increased significantly in 14 project areas. The integrated remote-sensing index revealed more nuanced regional responses, with forests and grasslands playing distinct roles across different ecological contexts.
A new study uses a thermal analysis technique to distinguish between different sources of organic carbon transported by rivers after extreme events, such as earthquakes and storms. The findings show that these events can continue to influence carbon transport in river systems for over a decade.
A new study reveals how generic electron interactions in 3D cubic lattices lead to Weyl topological superconductivity. The researchers found that repulsive electron interactions create a chiral d+id pairing state with an octupolar component, featuring eight gapless Weyl points.
Researchers identified nine typical disaster chain types driven by endogenic and exogenic dynamics, highlighting the need for interdisciplinary integration to understand complex geological disaster chains. The study also emphasizes the importance of 'multi-critical phase transitions' in understanding dynamic processes of disaster chains.
A new study maps the changing RNA modification landscape of sperm during development and shows that type II diabetes can disrupt this molecular program. The findings suggest that paternal metabolic disease can impact male fertility and potentially offspring health.
A new study reveals that decoupling in glass-forming liquids originates from high-temperature activation free energies, not dynamic heterogeneity. The researchers observed a universal power-law relationship between two characteristic timescales, which matched the predicted ratio with remarkable accuracy.
Ferroelectric memristors overcome computing hardware bottlenecks by processing data directly where it's stored. This enables significant reductions in data transfer overhead and improvements in computing efficiency.
Researchers propose a new framework, BOC, inspired by biological nervous systems to build more adaptive intelligent systems. The framework integrates sensing, memory, and computation directly at the hardware level, reducing data movement and latency.
Researchers developed an on-chip all-optical supernode for ultra-low-latency deep neural network inference, achieving a 100-fold increase in inference speed while using only one-ninth of computing resources. The system supports high-speed data routing and switching with low loss and flat response over a spectral range exceeding 100 nm.
Scientists at SUSTech and collaborators report first experimental observation of one-sided chiral hinge states in a 3D magnetic Weyl photonic crystal, verifying the 3D QHE of Fermi arcs. The discovery reveals a new physical mechanism for robust light transport in 3D space with potential applications in topological photonic devices.
Researchers examine the flow physics and modeling challenges governing EUV sources, highlighting the importance of debris control and multiscale fluid dynamics. The study aims to provide a common framework for laser-plasma and fluid mechanics communities, supporting future advances in EUV source performance.
Researchers stabilize fractional orbital angular momentum modes by confining them into stable integer-charged composite states. This 'locally fractional, globally integer' behavior provides a new route to control fractional vortices.
A nationwide China study analyzed 695,142 hospitalized patients and identified eight life-stage pathogen profiles, three co-detection networks, and marked male predominance in bacterial and fungal infections. The study found distinct shifts in microbes across infancy to old age, accompanied by sex disparities.
This study defines IFRD1's disease-protective function and elucidates its molecular regulatory mechanism, which suppresses de novo hepatic lipogenesis by boosting α-KG production. Clinical correlations and translational potential are also established for therapeutic interventions targeting the GLUD1/α-KG axis.
Ionic thermoelectric materials have been found to tap into low-grade waste heat with unusually high thermopowers, enabling applications such as wearable patches, smart buildings, and energy-harvesting smart windows. Challenges in standardization, scalability, and sustainability hinder commercialization.
The new photonic architecture harnesses three fundamental degrees of freedom: wavelength, mode, and polarization, achieving 192 parallel computing channels. The chip supports large, reconfigurable convolution kernels up to 13x13, capturing global structural contours while preserving fine details.
Researchers use unsupervised learning and neural networks to group anomalous Hall curves into distinct families, creating a roadmap for understanding complex magnetic behaviors. The framework predicts desirable properties and guides the search for rare quantum states.
A nationwide study across China reveals that fungal species with broad geographic distribution are the dominant drivers of soil carbon decomposition. These widespread saprotrophic fungi play a crucial role in shaping future carbon dynamics under climate change.
Researchers propose protein coronas as a dynamic navigation interface to shape how nanomedicines are recognized and delivered across the blood-brain barrier. The corona can be manipulated to bias circulation, targeting ligands, and intracellular trafficking for improved brain delivery.
Researchers develop Csp–π–d conjugated system to enhance oxygen reduction performance, outperforming platinum-based catalysts in stability and cost-effectiveness. The new catalyst facilitates electron transfer and weakens OH adsorption, promoting intermediate desorption and accelerating reaction kinetics.
A new artificial lateral-line sensing unit helps underwater robots estimate both magnitude and direction of local flow velocity. The sensor uses a flexible silicone spring, light-emitting diode, and photodiodes to detect subtle hydrodynamic changes in water flow.
A new cellulose-based material, celluplastic, exhibits high strength, flexibility, and transparency, rivaling conventional plastics. It can be fully recycled in water over 100 cycles without chemical degradation.
A large-scale study developed a predictive model for Lymph Node Metastasis (LNM) status in T1b gastric cancer using digital pathology and deep learning. The DL-T1 nomogram achieved an AUC of 0.910, indicating high accuracy in predicting LNM risk.
Researchers identify cholesterol ester buildup as biomarker predicting progestin therapy response in young women with endometrioid endometrial carcinoma. Combination treatment with progestin and a statin doubles six-month remission rate and helps patients become mothers.
A research team found that thalidomide may help stabilize and shrink sporadic CNS-AVMs by reducing endothelial ANGPT2 and increasing mural cell coverage. The drug showed promise in early clinical trials, with no lesion growth observed in 28 patients.
Researchers designed a Ce-Cu2O catalyst with dual active sites to regulate hydrogen utilization in electrochemical nitrate reduction reaction. The new mechanism enables cooperative L-H and E-R hydrogenation processes, improving ammonia selectivity under high current densities.
A comprehensive review synthesized decade-long efforts on ruthenium dioxide's altermagnetism, highlighting ongoing debates and proposed future research directions. The study suggests that epitaxial strain, defects, or interface effects may contribute to the observed magnetic properties of RuO2 thin films.
A new review reveals that spinal cord injury can trigger a cascade of systemic complications throughout the entire body, affecting organs far from the original injury site. The authors propose a neuro-immune-metabolic network framework for understanding these complications and suggest a shift towards proactive, system-wide recovery.
The review systematically maps out the research landscape of wearable AI doctors, combining power-harvesting approaches with self-powered intelligence. Flexible electronics enable devices to withstand dynamic environments, while on-device AI inference processes data locally for real-time analysis.
A viscoplastic interlayer composed of PIB and MAPP effectively seals non-planar electrodes, preventing biofluid ingress. The interlayer's conformal contact and tight binding block water permeation, ensuring long-term stability.
A study found that the spring SAM underwent a marked structural shift around 1998, strengthening its delayed influence on Antarctic summer sea ice. This shift led to enhanced ice-loss processes, including increased air-sea heat exchange and ocean warming in the Weddell Sea.
Researchers used snRNA-seq to study H2S signaling in Chinese cabbage, identifying 18 clusters of cell types and 9 major cell types. The study found that H2S induces globally coordinated transcriptional reprogramming and identifies two key genes enhancing drought tolerance.
Nucleosome assembly protein Nap1 safeguards genome integrity by regulating chromatin dynamics and guiding nuclear division. Its deletion disrupts cellular processes, leading to structural aberrations and genomic instability.
Scientists successfully demonstrated reversible topological phase transitions in β-Ag2Te using out-of-plane gate voltages. This breakthrough enables the creation of functional electronic components with high current on-off ratios, overcoming previous hurdles in practical application.
Researchers from Sun Yat-sen University discover a novel mechanism by which tsRNA-Gly promotes hepatocyte regeneration in ACLF. The study reveals that tsRNA-Gly activates GRHL1 and upregulates CCND1, driving liver regeneration.
A novel operator learning framework tackles the ill-posedness in inverse thermal problems by employing two synergistic deep learning components. The framework accurately estimates spatial material properties and filters high-frequency noise to project the final-state thermal field back to its initial distribution.
Research finds that advanced maternal age reduces autophagy in embryos from aged female mice, leading to impaired embryonic development. Supplementation with Rapamycin improves early embryonic development by regulating metabolic pathways.
A population-based study found that radical nephroureterectomy was associated with better overall and cancer-specific survival compared to kidney-sparing surgery. Tumor stage, size, lymph node dissection status, and patient-specific factors play a crucial role in individualized surgical planning.
Researchers identify hormone-driven molecular cascade enhancing K⁺ uptake in cotton under low-K⁺ conditions, revealing synergy between jasmonic acid and ethylene pathways. Foliar application of MeJA or ACC improves leaf K⁺ concentration and photosynthetic performance, increasing seed cotton yield by 11.6%.
A new study investigated the effects of ornidazole, an antimicrobial drug, on male fertility. Ornidazole was found to reduce sperm count and motility, as well as disrupt seminiferous tubule structure, in both mouse and human models.
Astronomers have discovered a new millisecond pulsar named PSR J1810−0623, featuring an exceptionally circular orbit. This discovery provides valuable information about binary evolution processes and the Galactic magnetic field structure.
Researchers identify CLASS 3G subtype of EGFR mutation associated with limited response to targeted drugs. This structural subtype alters protein shape, reducing treatment efficacy and allowing for more effective combination therapy.
The review highlights advances in multi-scale bioelectrical interactions, analyzing challenges such as interface impedance and material-tissue compatibility. It emphasizes a shift towards application-driven design, integrating biological needs with material selection and device engineering.
Topological methods have become a robust testing ground in black hole physics, revealing distinctive topological attributes of diverse black hole solutions. The review summarizes recent work toward universal topological classifications of black holes, organizing them according to their global topological number and winding numbers.
Researchers create siRNA delivery system based on IVSA technology, which targets EGFR-positive tumors with high efficacy and low toxicity. The system enables precise targeting and overcomes drug resistance challenges.
A new study reveals that climate change will reshape the surface sunlight map, making polar regions dimmer and mid-latitude areas brighter. The redistribution of sunlight may impact energy balance, snow and ice processes, hydrological cycles, and solar energy resources.
Methanol-to-hydrocarbons reactions exhibit multiscale heterogeneity due to differences in molecular diffusion, crystal structure, particle composition, and reactor conditions. This nonuniformity affects catalyst performance and product selectivity.
Researchers developed a quantum sensing approach using superconducting qubits, combining non-equilibrium dynamics and quantum criticality to measure gradient field strengths with quantum-limit precision. The method avoids complex measurement setups, enabling highly precise estimates of gradient field strengths with limited samples.
Researchers discovered that exercise enhances oxygen delivery to arthritic joints through tiny vesicles released from red blood cells, relieving tissue hypoxia and promoting joint health. Physical activity drives the circulation of these EVs into the joint, where they deliver oxygen and maintain joint function.