Researchers found whole-body vibration (WBV) to be as effective as regular exercise in improving bone formation and insulin sensitivity in obese mice. WBV was shown to mimic the metabolic effects of exercise, with benefits seen in both genetically normal and obese mice.
A mouse study found that prenatal BPA exposure weakens the body's fullness cues by reducing sensitivity to leptin, a hormone controlling appetite. This altered response can lead to increased obesity risk in offspring, supporting concerns about the potential impact of environmental endocrine disruptors on human health.
The Endocrine Society has honored 21 outstanding researchers with the Early Investigators Award, recognizing their contributions to endocrine research and women's health. The award recognizes achievements in metabolic bone research, women's health, menopause, and endocrine disorders.
The Endocrine Society has issued a new clinical practice guideline for pediatric obesity, emphasizing the importance of family-centered lifestyle modifications. The guideline provides recommendations for assessing, treating, and preventing childhood obesity, including genetic testing for rare causes.
A new study reveals that individuals with Type 1 diabetes exhibit distinct gut inflammation and microbiome changes compared to those without diabetes or celiac disease. The research found specific genes associated with gut inflammation and unique combinations of gut bacteria in patients with Type 1 diabetes.
A large study of over 9,000 men has established harmonized reference ranges for total testosterone, enabling clinicians to diagnose hypogonadism correctly. The normal range for testosterone in non-obese European and American men between 19-39 years is 264-916 ng/dL.
A new study found that most endocrinologists have never received formal training on caring for transgender individuals, despite growing demand for such services. The Endocrine Society is now developing guidelines to address the need for education and training in this area.
A large international survey found nearly two-thirds of women with PCOS waited over two years for a diagnosis and saw multiple healthcare providers before receiving a diagnosis. Women reported dissatisfaction with the length of time they waited and lack of information about treatments and long-term complications.
A new study found that low blood sugar in hospitalized patients is associated with increased short- and long-term mortality risk. The study's authors recommend increasing awareness of hypoglycemia and improving quality of care for patients who experience it.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism reveals that menopausal hormone therapy (MHT) improves both bone mass and structure, with benefits persisting for at least two years after treatment ends.
A new study found that injectable contraceptives for men can reduce the risk of unplanned pregnancies in their female partners. The hormone-based method, which involves injecting a combination of progestogen and testosterone, was effective in nearly 96% of continuing users.
A new study found that vitamin D supplements are less effective in raising levels in pregnant women if they deliver in winter or have low early pregnancy levels. Customized doses can be used to protect bone health and maternal health.
A new study found that resveratrol supplements can lower total testosterone levels by 23.1% in women with polycystic ovary syndrome (PCOS), while also improving diabetes risk factors such as fasting insulin levels. The results suggest resveratrol may be a promising treatment for PCOS and related metabolic problems.
The Endocrine Society recommends treating hypopituitarism by replacing hormones at natural patterns, with accurate hormone measurements crucial for diagnosis and treatment monitoring. The guideline also addresses special circumstances like pregnancy care and post-surgical care.
A new study has identified a connection between gut microbiota and fat distribution in children and teenagers, with obese youth having different microorganisms living in their digestive tracts. The research suggests that short-chain fatty acids produced by certain gut bacteria can contribute to the development of obesity.
A new study found that women who experience frequent nighttime hot flashes and sleep disruption are more likely to exhibit mild symptoms of depression. The researchers suggest menopausal women should be screened for mood disturbances, incorporating efforts to address sleep and nighttime hot flashes.
A new study found an association between exposure to endocrine-disrupting chemicals (EDCs) and lower vitamin D levels in U.S. adults, with the link strongest in women. The study suggests that EDCs may alter the active form of vitamin D in the body.
The Endocrine Society recommends continuous glucose monitors as the gold standard of care for adults with Type 1 diabetes, enabling better blood sugar control and reducing hypoglycemic events. The guideline also suggests using insulin pumps and emerging technologies like artificial pancreas devices to manage blood sugar levels.
Researchers exposed mice to 23 fracking chemicals, finding altered hormone levels and ovarian development. The study suggests adverse reproductive outcomes in animals and potentially people.
A new study found that women who stopped using estrogen-containing contraceptives had average vitamin D levels, while current users tended to have higher levels. Women trying to conceive should take action to maintain adequate vitamin D levels before and during pregnancy.
Women with polycystic ovary syndrome (PCOS) may benefit from incorporating soy isoflavones into their diets, according to a new study. The study found that consuming soy isoflavones regularly can lower levels of insulin in the blood and improve metabolic health.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that a combination of three medications—dapagliflozin, liraglutide, and insulin—helped people with Type 1 diabetes improve blood sugar control and lose weight. The therapy also showed impressive improvements in blood glucose management.
A large placebo-controlled study found that testosterone therapy significantly improved sexual interest and function in older men with low libido and low testosterone levels. The study, the largest of its kind, showed consistent improvement in most types of sexual activity among those who received testosterone therapy.
A new study found that both limited and excess sleep may raise diabetes risk in men, with those sleeping too much or too little having impaired glucose metabolism. In contrast, women who slept less or more than average were more responsive to insulin and had enhanced beta-cell function.
Researchers developed an index to predict bone loss in women during menopause by considering both bone formation and breakdown. The Bone Balance Index was found to be a stronger predictor of bone loss than a measurement of bone breakdown alone.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism has found that obese teenagers have lower levels of the hormone spexin, which may contribute to weight gain and obesity. The study suggests that spexin may play a role in regulating body fat mass and energy balance.
A new study found that air pollution exposure can worsen blood sugar levels, cholesterol and other risk factors for heart disease. Participants with diabetes experienced higher changes in blood glucose and cholesterol levels when exposed to higher levels of particulate matter.
Primary aldosteronism is a common cause of high blood pressure that frequently goes undiagnosed and untreated. The Endocrine Society recommends expanded screening for individuals with high blood pressure, particularly those who are at higher risk, to prevent associated cardiovascular complications.
The Endocrine Society is launching a new open-access journal, Journal of the Endocrine Society (JES), to rapidly publish cutting-edge science in endocrinology. The journal will cover topics such as diabetes, obesity, and hormone-related cancers.
A three-year study found that liraglutide can help nondiabetic overweight and obese adults lose weight and reduce their risk of developing Type 2 diabetes. After three years, 66% of participants taking liraglutide no longer had prediabetes.
A new study by the Endocrine Society finds that children and teenagers taking ADHD stimulant medications may have lower bone density, a condition that can increase fracture risk or osteoporosis later in adulthood. The study suggests that these patients may need monitoring of their bone health during treatment.
A new study suggests that a combined vaccine therapy using live Salmonella is safe and effective in preventing diabetes in mice. The vaccine works by rebalancing the immune system and preventing the attack on insulin-producing cells. Researchers believe this targeted immunotherapy has great potential for treating type 1 diabetes.
Research suggests that combining aromatase inhibitors with growth hormone can effectively and safely increase height in very short adolescent boys. The study found significant gains in height and lean body mass when using this combination therapy.
A new study reveals that only 1.02% of eligible patients receive weight loss medications, highlighting a significant gap between guidelines and treatment practices.
Researchers found that SSRI antidepressants cause decreased bone density in mothers during lactation, leading to higher risks of fractures. Folic acid supplementation may mitigate this effect, suggesting women may need more folic acid while breast-feeding.
A new study found that abaloparatide-SC increased bone mineral density in the spine and hip, reducing the risk of vertebral and nonvertebral fractures. The treatment also showed promise in a broad range of postmenopausal women with osteoporosis, regardless of baseline patient characteristics.
A new study suggests that taking antibiotics in early childhood may disrupt the gut's microbial ecosystem and increase the risk of developing prediabetes in adolescence. The researchers found that a depletion of beneficial bacteria, such as Ruminococcus species, was associated with higher rates of antibiotic use.
In a clinical trial of 100 obese men, researchers found that adding testosterone treatment to calorie restriction resulted in increased fat loss and preserved muscle mass. The study suggests that testosterone treatment may be a useful adjunct to weight loss in obese men with low testosterone levels.
A new study found that AMH levels are related to high testosterone secretion and abdominal adiposity, making it a possible surrogate for ovarian antral follicle number. Additionally, AMH levels were correlated with age and body mass index, indicating its potential as a biomarker for PCOS diagnosis in obese adolescent girls.
New research from South Korea suggests that higher dietary calcium intake may lower the risk of cardiovascular disease in older people, but not stroke and fracture risk. In a population with low calcium intake, higher dietary calcium was significantly associated with decreased risk of CVD.
Researchers have discovered a new potential therapy that can protect transplanted human pancreatic islets from dying. The study suggests that pretreating cells with a peptide hormone called cholecystokinin (CCK) may enhance the curative potential of islet transplant for Type 1 diabetes.
A new study found that combining a temporary intestinal bypass device with the drug liraglutide improves diabetes control and weight loss in patients. The combination treatment resulted in significant weight loss (12.8 kg) and improved glycated hemoglobin levels compared to other treatments.
Researchers at Northwestern University developed an ovary bioprosthesis implant using a 3D printer, allowing mice to bear live young after ovary removal. The technology aims to restore fertility and hormone function in women affected by cancer treatments or born with reduced ovarian function.
Researchers investigate how changes in light exposure may contribute to breast cancer development. Extended periods of nighttime illumination disrupted normal cellular behaviors and gene expression, particularly in hormone-dependent tissues like the breast.
A study of nearly 4,000 children found that infants with high BMI as young as 4-6 months are at risk of early-childhood obesity. Infants with BMI above the 85th percentile by 6, 12, or 18 months are strong predictors of severe obesity by age 6.
Whey protein diet participants lost the most weight and experienced reduced hunger and glucose spikes compared to other diets. The study found that a high-protein breakfast containing whey protein induced greater satiety and reduction of glucose spikes after meals.
Researchers found that brominated fire retardants stimulate an adrenal gland hormone, leading to potential development of cardiovascular disease. The study's results suggest a link between these chemicals and high blood pressure, cardiac hypertrophy, and congestive heart failure.
A new study suggests that liraglutide, a diabetes drug, reduces the brain's reward response to high-fat foods, making them less desirable. This effect may be beneficial for individuals with Type 2 diabetes who tend to overindulge in fatty foods as a coping mechanism.
A study published in the Endocrine Society reveals that anabolic steroid abuse is associated with severe blood pressure increase and hypertension. The research found that daytime and nighttime blood pressures were higher among ongoing AAS abusers compared to former abusers and non-users.
A study of 41 male veterans found that blast concussions frequently result in hormone changes, causing problems like fatigue, depression, and poor quality of life. Researchers detected hypopituitarism in 44% of affected veterans, with those experiencing hormonal abnormalities showing poorer sleep quality and increased depressive symptoms.