Researchers at University College London have identified a new mechanism for how polycomb proteins repress the wrong genes in embryonic stem cells. The discovery has significant implications for tissue engineering and cell differentiation, as it reveals how polycomb proteins control gene activity through interaction with short RNAs.
A recent study published in Cognitive Development found that teenagers take the most risks compared to other age groups, particularly between 14-35 years old. The researchers discovered that teenagers enjoy the thrill of taking risks more than other age groups, especially when they have a 'lucky escape'.
A new species of dromaeosaurid, Linheraptor exquisitus, has been discovered in Inner Mongolia with a near complete skeleton found since 1972. The fossil reveals unique features, including an antorbital fenestra, and is closely related to Velociraptor.
A study by UCL scientists found that people tend to accept the status quo and avoid making complex decisions, even when it leads to errors. The study used fMRI scans to examine the neural pathways involved in 'status quo bias' and discovered a key role for the subthalamic nucleus in overcoming this bias.
A new mental health outreach programme has successfully identified and treated hundreds of survivors of the 2005 London bombings, strongly suggesting similar programmes need to be included in disaster response plans. The programme highlighted a significant gap in traditional GP referrals for mental healthcare after terrorist attacks.
New research at UCL suggests that moderate alcohol consumption before a traumatic event can lead to increased recall of the traumatic experience, resulting in more frequent flashbacks. In contrast, high levels of alcohol consumption may disrupt both types of memory, leading to fewer flashbacks and reduced overall memory for the event.
Research at University College London found that genetic differences are responsible for the majority of variation in face recognition ability among individuals. Identical twins showed a stronger correlation in their face recognition skills compared to non-identical twins, indicating a significant role of shared genes.
Researchers at University College London have uncovered a previously lost Roman law code, the Codex Gregorianus, which dates back to AD 300. The fragments contain responses by emperors to public questions on legal matters, offering new insights into ancient Roman law and its enduring legacy.
Researchers at University College London have identified 'grid cells' in the human brain for the first time, which may help explain how we create internal maps of new environments. These specialized neurons are involved in spatial memory and have been previously discovered in rodent brains.
A new eye test technique enables real-time measurement of brain cell death, refining diagnosis and tracking disease progress in Alzheimer's. The method uses fluorescent markers to directly observe retinal nerve cell death, which could lead to successful reversal of the disease with treatment.
A comprehensive review of electronic patient record (EPR) programs reveals significant challenges in implementing and maintaining these systems. The study highlights how EPRs can hinder primary clinical work, favor paper-based records for flexibility, and struggle with seamless integration between different systems.
A survey of UK drug users found that they rate legal substances like alcohol and tobacco as more harmful than Class A substances, suggesting a flaw in the current classification system. The study also found high correlations between user ratings and expert ratings, indicating users are well informed about drug harms.
A new study from University College London finds that dopamine plays a significant role in shaping human expectations of pleasure, particularly when considering alternative options. The research suggests that dopamine signals the expected pleasure from future events, guiding decision-making.
Researchers discovered two distinct short-term memory networks: one independent of the hippocampus and another dependent on it, which are impaired alongside long-term memory. Patients with impaired long-term memory have a significant short-term memory burden.
Two genetic mutations, CARD9 and Dectin-1, have been identified as increasing the risk of fungal infections in humans. These findings offer new insights into the genetic basis of fungal diseases and may pave the way for future therapeutic options for patients suffering from chronic mucocutaneous candidiasis and other infections.
New research suggests that Europe's first farmers migrated into central and Eastern Europe around 7,500 years ago, bringing domesticated plants and animals with them. The study analyzed DNA from hunter-gatherer and early farmer burials, finding little evidence of a direct genetic link between the two groups.
A study of over 40,000 participants found that those who prefer immediate gratification are more likely to show other impulsive behaviors such as smoking and infidelity. The research suggests that individuals with an impulsive money-today attitude may ignore long-term consequences, leading to financial imprudence.
A new study by University College London scientists reveals that the ability to digest lactose first evolved in dairy farming communities in central Europe around 7,500 years ago. This genetic change enabled early Europeans to drink milk without getting sick, providing a survival advantage.
A new technique uses microscopic magnetic particles to target stem cells to sites of cardiovascular injury, resulting in a five-fold increase in cell localization and six-fold increase in cell capture. The method is directly applicable to clinical practice and could lead to the treatment of heart attacks and other vascular injuries usi...
A new study suggests that high population density catalyzed the emergence of modern human behavior, driven by increased exchange of ideas and skills. This skill maintenance, combined with a greater probability of useful innovations, led to the appearance of modern human behavior at different times in different regions.
A new UCL study reveals over half of £20 million compensation paid to British slave owners was used to fund modern Britain. The 'Legacies of British Slave Ownership' project creates the first online database of British slave owners, highlighting their economic, cultural, and social impact.
Researchers at UCL have identified a protein, SAP, as a potential therapeutic target for Alzheimer's disease. CPHPC, a new small molecule drug, removes SAP from the blood and brains of patients with Alzheimer's disease, showing promising results.
Researchers from University College London have developed a new device to enable people living with HIV to monitor their own health and treatment effectiveness. The device uses nano-cantilever arrays to measure HIV markers, providing patients with clear, immediate advice on their condition.
Patients with schizophrenia can correctly identify a 'hollow mask' illusion, which may be related to their brains disconnecting visual information from internal thoughts. The study also found that cannabis users are less deceived by the illusion, suggesting a possible link between THC and brain connectivity.
A novel injectable, OCR-002, directly reduces blood levels of ammonia, a toxic chemical building up during acute hepatic encephalopathy attacks. Clinical trials will begin in 2009 to develop the treatment for patients with advanced liver cirrhosis and acute liver failure.
Researchers at the London Centre for Nanotechnology have discovered a novel one-dimensional ice chain structure built entirely from pentagons, challenging the long-held assumption that hexagons are the building blocks of ice. This discovery has significant implications for understanding hydrogen bonding at interfaces and may lead to ne...
A new study published in PLoS ONE found that children who carry the 'obesity gene' can offset its effects by eating a low energy density diet. The research, based on data from over 2,000 children, suggests that adopting a healthier diet with fewer calories per bite may help prevent weight gain and obesity.
A new study from University College London found that internal choices can be easily overridden by external stimuli, revealing a flexible brain. The researchers discovered that changing an internal choice is easier than making one based on external instructions, highlighting the importance of adaptability in decision-making.
A new psychodynamic approach, CAPSLE, focuses on empathy and power dynamics to reduce children's experiences of aggression and improve classroom behavior. The study found that schools implementing CAPSLE reported fewer aggressive incidents and more positive bystanding behaviors.
Researchers modelled gene evolution alongside language development, concluding that genetic adaptation to language is unlikely due to rapid cultural change. The study suggests that human language has evolved primarily through cultural conventions rather than biological adaptation.
A mathematical model by UCL researchers explains how extended courtship enables a male to signal his suitability and the female to screen out unsuitable mates. The study shows that long courtship carries information about the male's type, making it more probable that he is a good male over time.
A new study at University College London found that nitrous oxide enhances imagination vividness and imaginary suggestibility in participants, which could lead to improved pain relief for dental patients. The study's findings suggest that combining laughing gas with instructions and suggestions might enhance the pain-relieving effect.
Climbers on an expedition led by UCL doctors reached record-low oxygen levels in their blood, averaging 3.28 kPa, which is significantly lower than the normal human range of 12-14 kPA. The study aims to inform critical care treatment strategies for patients with low oxygen levels.
Research at UCL found premature infants who required intensive care or surgery have reduced sensitivity to temperature and pain later in life. This study, published in the journal Pain, suggests that early medical interventions may alter how children respond to painful stimuli.
Researchers at UCL developed a new universal test to predict the risk of major depression, which was tested in 6,000 people and found accurate in predicting future episodes. The tool, predictD, could be used by family doctors and local clinics to identify those at risk for whom prevention might be most useful.
Researchers have captured a rare binary star explosion inside a planetary nebula, offering new insights into stellar evolution. The study predicts that the combined mass of the two stars could lead to a larger supernova explosion.
Physicists at UCL and the London Centre for Nanotechnology have made a significant discovery in quantum computing, extending the quantum lifetime of electrons by over 5,000%. This achievement brings researchers closer to building a usable quantum computer. The study used a powerful magnetic field to align electron spins, providing a cr...
Researchers at UCL found a 'hate circuit' in the brain that is distinct from those related to love, fear, and aggression. The study reveals that the 'hate circuit' involves structures in the cortex and sub-cortex that are also activated by romantic love, but with a different pattern of activity.
A woman with phonagnosia, unable to recognize her daughter's voice on the phone, undergoes tests that reveal difficulties in recognizing famous actors' voices but not other sounds or music. The study suggests there may be more people with similar conditions, and researchers seek contact from potential sufferers.
The discovery of ancient DNA in 9,000-year-old bones found off the coast of Israel reveals that human tuberculosis is 3,000 years older than previously thought. The study confirms that the human strain of TB evolved before bovine TB and sheds light on its evolution over time.
Researchers have developed ultra-sensitive probes to investigate vancomycin's working mechanisms, paving the way for more effective new drugs. By detecting surface stress on bacteria, scientists can identify the disruption of cell walls and potentially develop more powerful antibiotics.
Researchers predict when Kondo effect occurs based on magnetic atom geometry, enabling new nanoscale devices. The discovery represents a major advance in understanding this fundamental physical phenomenon.
Researchers at University College London have combined silicon, iron, and manganese to create a new material with unique properties. The discovery demonstrates a simple recipe for reaching this 'quantum halfway house' and suggests new mechanisms for controlling electrical currents and magnetism in semiconductor devices.
A new study by UCL and the University of Melbourne found that Aboriginal children from restricted vocabularies could copy and perform number-related tasks. They were able to recognize and represent numerosities without relying on number words, suggesting an innate system for counting.
A genetic variation that protects against malaria increases susceptibility to HIV by up to 40%, yet also prolongs survival by approximately two years. This finding highlights the complex relationship between genetics and HIV/AIDS, with implications for targeted prevention strategies.
Researchers found abnormally high levels of cytokines in blood of Huntington's disease gene carriers years before symptoms appeared. White blood cells and microglia also showed hyperactivity, suggesting abnormal immune activation could be an early disease hallmark.
A recent study published in Science found that 57% of researchers were 'mostly pleased' with their media interaction, while only 6% were 'mostly dissatisfied'. The survey, conducted among 1354 scientists, suggests that science-journalist interactions are more positive than previously thought.
Archaeologists have discovered a treasure trove of stone tools at a site in West Sussex, revealing a thriving and developed population of northern Europe's last Neanderthals. The tools, which date back to between 35,000 and 42,000 years ago, showcase the group's sophisticated hunting skills and technological prowess.
Historical records show the evolution of signing and interpreting in court proceedings from 1725 to 19th century, highlighting the role of education and community in shaping British Sign Language. As deaf people gained access to education, their status in courts declined paradoxically.
A recent study from University College London suggests that investors' emotional states play a significant role in the stock market's behavior. The researchers argue that 'emotional inflation' - the unchecked enthusiasm and wishful thinking that can lead to excessive risk-taking - is a major contributor to market crashes.