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University of Basel


Math boosts brain research

Researchers at the University of Basel used computational models to describe human memory processes for the first time. The study identified specific genetic profiles underlying distinct mental processes, such as learning and memory storage.

SourceUniversity of Basel·JournalProceedings of the National Academy of Sciences·DateAug 10, 2015

Stress hormone reduces heroin cravings

Researchers found that cortisol administration significantly reduced cravings for heroin in addicts, with a 25% decrease seen on average. The study suggests that cortisol may have inhibitory effects on addiction-related memory and behaviors.

SourceUniversity of Basel·JournalTranslational Psychiatry·DateJul 28, 2015

Is marriage good or bad for the figure?

A comparative study of 9 European countries found that married couples have a higher body mass index than singles, with differences attributed to changes in eating behaviors. However, the study also shows that married couples tend to eat healthier, with increased consumption of regional and organic products.

SourceUniversity of Basel·JournalSocial Science & Medicine·DateJun 29, 2015

Fructose produces less rewarding sensations in the brain

A study by University of Basel researchers found that fructose stimulates the reward system in the brain to a lesser degree than glucose, leading to increased satiety hormone levels and reduced feelings of fullness. This may contribute to the development of various disorders such as obesity, diabetes, and fatty liver disease.

SourceUniversity of Basel·JournalPLOS ONE·DateJun 25, 2015

The pertussis pathogen -- New findings

Researchers discovered that the protein structure of a key membrane protein differs from a previously postulated model, providing a basis for new treatments. The study reveals how the protein pore opens and closes in response to substrate binding, offering insights into the pathogen's attachment mechanism.

SourceUniversity of Basel·JournalNature Communications·DateJun 23, 2015

Psychology: Does aging affect decision making?

Older adults perform just as well as younger adults in simple decision-making, according to a study published in Cognition. However, in more complex decisions, older adults may struggle due to age-related cognitive decline. The study suggests that simple learning strategies can be useful for aging decision makers despite limitations.

SourceUniversity of Basel·JournalCognition·DateJun 1, 2015

Memories influence choice of food

A study published in Neuron found that people tend to prefer snacks they can recall better, even if they are less attractive. The researchers used fMRI scans and mathematical modeling to understand how memory influences decision-making, revealing an increase in communication between the hippocampus and ventromedial prefrontal cortex.

SourceUniversity of Basel·JournalNeuron·DateMay 21, 2015

Mental disorders and physical diseases co-occur in teenagers

A recent study published in Psychosomatic Medicine found that mental disorders and physical diseases often co-occur in teenagers. The strongest correlations were found between affective disorders (e.g. depression) and diseases of the digestive system, as well as anxiety disorders and arthritis. These associations highlight the need for...

SourceUniversity of Basel·JournalPsychosomatic Medicine·DateApr 8, 2015

Depression often co-occurs with joint diseases

A study of 14,348 Swiss individuals found that those with depressive symptoms have a higher risk of developing physical diseases, especially arthrosis and arthritis. The researchers suggest that lack of interest in physical activity or inflammatory processes may be key factors in this association.

SourceUniversity of Basel·JournalFrontiers in Public Health·DateApr 1, 2015

Toward Methuselah -- long-living lighting devices

Researchers at the University of Basel have made significant advancements in developing next-generation lighting technologies. The team has successfully created light-emitting electrochemical cells (LECs) with remarkable lifetimes exceeding 2500 hours, paving the way for a more efficient and cost-effective alternative to traditional LEDs.

SourceUniversity of Basel·JournalChemical Science·DateMar 9, 2015

New cicada species discovered in Switzerland and Italy

Researchers at the University of Basel have discovered a new singing cicada species in Italy and southern Switzerland with a four-centimeter wingspan and high-pitched song. The 'Italian Mountain Cicada' has been identified through its distinctive song pattern, which includes slow phrases alternating with fast and rhythmic ones.

SourceUniversity of Basel·JournalZoological Journal of the Linnean Society·DateFeb 26, 2015

Parasite eggs from the Celtic period found in Switzerland

Archaeologists discovered intestinal parasites' eggs from the Celtic period in Switzerland, indicating poor sanitation and mixed living environments. The parasite eggs suggest a lack of proper waste management and possible livestock introduction, highlighting the challenges faced by ancient communities.

SourceUniversity of Basel·JournalJournal of Archaeological Science·DateDec 29, 2014

Nanotechnology against malaria parasites

Researchers at the University of Basel have developed nanomimics of host cell membranes that trick malaria parasites. These nanomimics effectively disrupt the parasite's cycle, blocking its invasion of new red blood cells while exposing it to the immune system.

SourceUniversity of Basel·JournalACS Nano·DateDec 9, 2014

Cooling with the coldest matter in the world

Researchers cool membrane vibrations to less than 1 degree above absolute zero, opening up possibilities for novel studies of quantum physics and precision measurement devices. The technique harnesses the unique features of ultracold atomic gases, enabling fundamental quantum physics experiments with macroscopic mechanical systems.

SourceUniversity of Basel·JournalNature Nanotechnology·DateNov 24, 2014

A twisted world -- chemists build a molecular banister

Researchers at the University of Basel have created a helical molecule with unique properties, where one strand winds around a central axis like a staircase banister. This 'twisted world' enables dynamic changes in chirality, opening up new possibilities for basic research and industrial applications.

SourceUniversity of Basel·JournalAngewandte Chemie International Edition·DateNov 12, 2014

Swiss scientists explain evolution of extreme parasites

Swiss researchers have discovered a new parasite species that represents the missing link between fungi and extreme parasites. The study reveals that microsporidia adopted intracellular parasitism first, followed by genome modifications such as the loss of mitochondria and metabolic simplification.

SourceUniversity of Basel·JournalProceedings of the National Academy of Sciences·DateOct 13, 2014

Uncovering the forbidden side of molecules

Scientists have successfully observed the 'forbidden' infrared spectrum of a charged molecule for the first time. This achievement enables precise measurements of molecular properties with unprecedented accuracy. The research has significant implications for the development of molecular clocks, quantum technology, and fundamental physics.

SourceUniversity of Basel·JournalNature Physics·DateSep 21, 2014

From nose to knee: Engineered cartilage regenerates joints

Researchers have successfully engineered cartilage tissue using nasal septum cells, showing promising results in repairing articular cartilage defects. The treated patients' knees were replaced with the engineered cartilage grafts, demonstrating the potential of this innovative clinical treatment for cartilage damage.

SourceUniversity of Basel·JournalScience Translational Medicine·DateAug 28, 2014

Aberrant mTOR signaling impairs whole body physiology

Research at the University of Basel reveals that aberrant mTOR signaling in the liver affects not only hepatic metabolism but also entire body physiology. The study found that activation of mTORC1 in the liver reduces locomotor activity, body temperature, and lipid metabolism.

SourceUniversity of Basel·JournalProceedings of the National Academy of Sciences·DateAug 11, 2014

Cancer risk: Aspirin and smoking affect aging of genes

Researchers have discovered that aspirin use slows down certain aging processes of the genome, while smoking accelerates them. The study found a significant correlation between aspirin use and reduced DNA methylation changes in healthy women over 50 years old, suggesting a possible mechanism for cancer prevention.

SourceUniversity of Basel·JournalJNCI Journal of the National Cancer Institute·DateJul 1, 2014

Nanoscale velcro used for molecule transport

Scientists at the University of Basel have discovered that proteins within nuclear pores function like a 'velcro', enabling controlled and selective transport of particles. This discovery has potential applications in lab-on-a-chip technology, where it could be used to miniaturize complex pump and valve systems.

SourceUniversity of Basel·JournalNature Nanotechnology·DateJun 25, 2014

Lipids help to fight leukemia

A new study by Prof. Gennaro De Libero and his team at the University of Basel identifies a lipid molecule, methyl-lysophosphatidic acid (mLPA), that stimulates specific T cells to kill leukemia cells. This breakthrough discovery offers new avenues for non-invasive cancer immunotherapies.

SourceUniversity of Basel·JournalJournal of Experimental Medicine·DateJun 16, 2014

Protein sharpens salmonella needle for attack

A study published in Cell Reports reveals that a specific protein, EIIAGlc, is essential for Salmonella's ability to inject toxins into host cells and manipulate host processes. The discovery opens up new avenues for developing targeted treatments against life-threatening Salmonella infections.

SourceUniversity of Basel·JournalCell Reports·DateMay 15, 2014