A new mutation in the mt-Cyb gene of a mouse model for GRACILE syndrome drastically speeds up disease progression. The discovery provides a valuable tool for studying mitochondrial diseases and their function.
A study by University of Helsinki professor Jan-Erik Lönnqvist found that self-centred men with disagreeable personality traits are more likely to own high-status cars and break traffic regulations. Conscientious individuals, on the other hand, also prefer high-status cars due to their desire for reliability and quality image.
Researchers from the University of Helsinki, led by Professor Minna Palmroth, have discovered a new auroral form called 'dunes' through citizen science collaboration. The phenomenon is believed to be caused by waves of oxygen atoms glowing due to solar particles, and provides a novel way to investigate upper atmospheric conditions.
A recent study published in BMJ Open found that zinc lozenges did not shorten the duration of common colds, contradicting previous findings. The researchers suggest further research is needed to determine optimal dosage and type of lozenges for effectiveness.
Researchers have discovered ways to boost CAR T-cell therapy, surveying over 500 cancer drugs on its function. SMAC mimetics sensitize cancer cells to CAR T cells, while inhibiting CAR T cell functions could treat adverse effects.
A recent study found that oral infections are not linked to increased risk of death or serious infection after stem cell transplantation. The researchers suggest that conservative dental treatment may be sufficient for patients with asymptomatic dental infections, and radical treatment is only necessary in specific cases.
A new study reveals under-sampled regions across Arctic, with research gaps in Botany, Biogeochemistry, and others. The findings highlight the need for increased sampling in areas like Canadian Arctic Archipelago and northern Siberia.
A recent study found that biodiversity in the Camargue has substantially changed, with declines in grasshoppers, crickets, and amphibians detected. The research also revealed increases in vascular plants and some bird species, but highlights the failure of current protection measures to safeguard certain taxa.
Researchers found that humidity and aspect of the tick's environment impact the types of bacteria carried by ticks. Borrelia afzelii is more common in humid slopes facing north, while Rickettsia species are prevalent on drier, steeper slopes.
Scientists at University of Helsinki and Institut Jacques Monod have identified a molecular machinery that drives rapid depolymerisation of actin filaments and recycles resulting monomers. This discovery provides new avenues for developing therapeutics to inhibit cancer cell migration.
Researchers found that female mongooses abort pregnancies more frequently during times of food scarcity and high competition. The study suggests that this adaptive strategy enables females to save energy for future breeding attempts.
The study reveals that locomotion mode is a strong predictor of cerebellar size, shape, neuron organization, and gene expression levels, indicating a specific type of brain shared by animals with similar lifestyles. High-definition 3D models of lizard and snake brains were used to uncover these correlations.
A recent study found that Finnish rivers are transporting 280,000 tonnes more carbon to the Baltic Sea each year than in the early 1990s. The increase is primarily attributed to climate change and its effects on precipitation and temperature.
Researchers at the University of Helsinki developed an artificial intelligence-based algorithm to improve intensive care for patients with severe traumatic brain injuries. The algorithm accurately predicts patient mortality within 30 days, showing promising results in a proof-of-concept study.
Researchers developed a rapid diagnostic method for detecting celiac disease antibodies, offering a promising solution to overcome the vast underdiagnosis of this condition. The new method, called RFS, can provide results in less than half an hour, significantly reducing the time and complexity of current testing procedures.
A recent study by the University of Helsinki found a significant link between increased use of antibiotics and an elevated risk of developing Parkinson's disease. The study suggests that excessive antibiotic use can disrupt the gut microbial ecosystem, leading to pathological changes in the intestine years before typical symptoms appear.
A genetic study of ancient bone samples in Finland discovered separate populations during the Iron Age, influencing modern Finns' gene pool. The study found lineages typical of hunter-gatherers and European farmers coexisted in different regions.
Recent studies found that smokers and hypertensive individuals have better chances to survive subarachnoid hemorrhage than non-smokers and those with normal blood pressures. However, a new Finnish study included patients who died before reaching hospital wards and showed the opposite - that these groups are more likely to die from brai...
Researchers developed a computational model, Combined Essentiality Scoring (CES), to accurately identify essential genes in cancer cells. The model predicts cancer essential genes with higher accuracy than existing methods and suggests two predicted genes as potential drug targets for breast cancer and leukemia.
Scientists from the University of Helsinki have created a computer algorithm that measures online discussions about endangered species, such as rhinos. The method successfully identified major events, including the death of the last northern white rhino, and highlights the importance of public sentiment in conservation.
Researchers found that northern tree species, including pine, birch, and spruce, release nitrous oxide into the atmosphere. The emissions vary by season, with peaks in summer, and are linked to physiological activity. The study suggests trees play a significant role in the global N2O balance.
A recent study has identified the gene function that protects against type 2 diabetes, revealing a zinc transporter's role in insulin secretion. The research found that individuals with a specific mutation in the SLC30A8 gene have enhanced glucose-stimulated insulin secretion and reduced blood sugar levels.
Scientists have created a quantitative map of radioactive cesium-rich microparticle distribution in Fukushima soils, shedding light on their origin and environmental impact. The study suggests three regions of particular interest, with varying levels of microparticle abundance and radioactivity.
A team of researchers found that the last woolly mammoths on Wrangel Island survived for another 7,000 years without significant changes in their diet or environment. However, when they finally died out, it was due to extreme weather events and potentially human activity.
A worldwide study found that sleep patterns differ among 16-30 year olds, with varying durations and timings based on age, sex, and region. The study tracked nearly quarter of a million nights of sleep using wearable devices, revealing significant geographical and gender-based variations in sleep habits.
Researchers at the University of Helsinki have identified 35 genetic loci associated with plasma lipid species levels, revealing a significant heritable component in cardiovascular disease risk. The study also highlights the potential of lipidomics to improve cardiovascular risk prediction and treatment.
Scientific research reveals that music is essential for expressing and enforcing relationships between humans, other beings, and ecosystems. Traditional music-making systems are being eroded due to globalization, but they continue to be honoured and celebrated.
Researchers developed an exosome-based nanomedicine that increases tumor accumulation and penetration after intravenous administration. The biocompatible nanomedicines combine natural biomaterials with synthetic nanoparticles, demonstrating potential for improved anticancer drug efficacy.
A survey of 16,475 households found that raw pet food was a contaminant in only three households, with most common pathogens being Campylobacteria and Salmonella. Most households did not report any infections, with 99.6% reporting no pathogen transmission from raw food.
A Finnish study found that individuals with more allergic diseases are at higher risk for developing adult-onset asthma, especially among those born after 1940. The research suggests that even one allergic disease can approximately double the asthma risk, while three or more diseases can quadruple it.
A new technique allows rapid degradation of targeted cellular proteins within minutes, enabling researchers to study protein functions and diseases. The method has potential for novel diagnostic and therapeutic methods, improving our understanding of cell biology.
A recent study found that while protected areas are reducing deforestation, their effectiveness varies, and conventional management indicators do not show the whole picture. Approximately half of the studied areas showed no deforestation, and 29 out of 36 had a positive impact in mitigating deforestation.
Researchers have discovered primitive picrite lavas that may provide the first direct sample of a hot mantle plume underneath southern Africa during the Jurassic period. The Luenha picrites show compositional similarities to magmas formed in other deep mantle plume-related volcanic provinces worldwide.
A Finnish study of over 2 million individuals reveals that mental disorders experienced in adolescence and early adulthood can have a lasting impact on employment. Individuals who were hospitalised for serious mental disorders before turning 25 had significantly poorer job prospects, with less than 10% employed after 25.
A new study using miniaturized satellite-based tags revealed that desert bats must fly further and longer during dry periods to meet their nightly needs. This suggests their struggle in coping with harsher conditions, highlighting the importance of understanding animal responses to climate change.
A study by University of Helsinki found that 84% of Finnish trotters had soft tissue damage in the bit area, with mild, moderate, and severe lesions detected. The researchers hope their developed classification system will facilitate comparative research.
A Finnish study has found that bowel preparation before colon surgery does not reduce surgical site infections or complications. The study of 400 patients showed no benefits to the procedure, suggesting it may be unnecessary.
A recent study found that excessive screen time in Finnish children is associated with both overweight and abdominal obesity. The research, based on data from over 10,000 children aged 9-12, suggests a strong link between sedentary screen use and weight gain.
The study found that adjuvant radiotherapy improved disease-free period for patients with locally advanced prostate cancer, with 82% of patients in the treatment group remaining disease-free. However, the treatment did not significantly impact survival rates.
A new study found that only four countries (USA, Australia, South Africa, and Canada) dominated private land conservation research, with half of articles failing to report stakeholder engagement. The study calls for better understanding of socio-ecological systems and diverse cultural contexts in future research.
Researchers discovered that aging factors from neighboring cells, known as Paneth cells, decrease the regenerative potential of intestinal stem cells. Inhibiting these signals, such as Notum, can promote tissue repair and recovery in aged animals.
Finnish researchers compiled guidelines for international use of music to support spoken language development in hearing-impaired children. Music, particularly singing, benefits the brain and perception of speech and prosody in these children.
A study by archaeologists at the University of Helsinki reveals that copper in ancient Finnish jewellery originated from southern Europe, particularly Greece and Bulgaria. The findings demonstrate extensive exchange networks between continental Europe and Finland across the Baltic Sea.
A Finnish study found that even moderate physical exercise, such as walking or cycling, can reduce the risk of subarachnoid hemorrhage by up to 20%. Quitting smoking is also crucial in preventing SAH, with exercise having a significant impact on risk factors like high blood pressure.
Researchers at the University of Helsinki and OIST have developed a novel method to create hybrid Au/Fe nanoparticles with unprecedented complexity. This breakthrough enables precise control over shape, size, and elemental composition, opening up new avenues for emerging applications.
The current Norwegian Barents Sea oil spill risk governance framework is inadequate for integrating multiple risk frames and knowledge systems. Social learning and collaborative knowledge production are essential for developing a shared understanding of the problem situation and solutions.
Researchers discovered that behavioral traits are highly heritable, explaining differences between breeds. The study analyzed data from over 6,000 cats representing three breeds: Maine Coon, Ragdoll, and Turkish Van.
A recent study published in Nature reveals that ancient bones found in a Finnish lake contain DNA from the modern Sámi people, dating back to around 500-700 AD. The discovery contradicts previous theories about local populations and sheds light on the colonization history of Siberia.
A study examined which conditions were considered illnesses by different groups, revealing a significant difference between psychiatrists and non-medical professionals. The results underscore the importance of understanding societal attitudes towards mental health, as these perceptions influence resource allocation and stigma.
Researchers used cryogenic electron microscopy to visualize the virus's protein shell and its condensed genome, which forms a liquid crystal state. The study sheds light on how viruses replicate and may contribute to tackling viral diseases.