Researchers found that adolescent binge-drinking can alter brain development and lead to increased anxiety-like behaviors and a preference for alcohol in adulthood. Epigenetic changes, which affect how genes are expressed, play a key role in these effects.
Researchers created a nanobot on a bacterial spore, using graphene quantum dots to detect changes in humidity. The device, called NERD, responds 10 times faster and is more sensitive in low-humidity situations.
Researchers found that mapping ICD-10 to ICD-9 is complex and challenging, with convoluted mappings and some codes not translating at all. A new web portal tool provides guidance on ambiguous translations, helping clinical researchers and analysts work with both old and new codes.
Research suggests that African American men with pre-diabetic blood sugar levels have fewer beneficial and more harmful intestinal bacteria. The study found that a specific microbiota is associated with stable, normal blood glucose levels, while a different profile is linked to pre-diabetes.
Researchers discovered a genetic variation, STK11 SNP, significantly increasing the risk of developing multiple sclerosis in women. The study involved three sisters among five siblings with MS and found the variant to be prevalent in 7% of the general population.
A team at the University of Illinois Chicago has identified a signaling mechanism that permanently places lung cells into a state of suspended animation called senescence. This finding represents a new potential therapeutic strategy for treating lung cancer by inducing senescence through this pathway.
A six-year clinical trial found that patients with low blood flow to the back of the brain are at a higher risk of recurrent stroke. The study used specialized software to visualize and quantify blood flow, identifying a quarter of patients with low posterior blood flow.
Researchers at the University of Illinois at Chicago found that damaged DNA can cause a molecule to slow down its patrol, giving it more time to recognize and initiate repair. The protein XPC, important for DNA repair, stalls at damaged sites due to twisted damage, allowing it to open and fix the damage.
A novel molecular mechanism has been uncovered that tightens the bonds between cells lining blood vessels in mice, potentially preventing fluid leakage and improving survival rates. The discovery could lead to the development of new therapies targeting acute respiratory distress syndrome (ARDS), a fatal condition in approximately half ...
Research at the University of Illinois at Chicago found that playing catch can improve balance and prevent falls in seniors by enhancing anticipatory postural control. The study also showed a transfer effect, where training improved performance on other tasks beyond the specific activity.
Researchers aim to enable scientists to ask a computer a question and receive an answer in an easy-to-understand picture. The project, funded by the National Science Foundation, seeks to develop an interactive computer system that can produce meaningful visualizations based on natural language requests.
Scientists used genetic analysis and mathematical modeling to discover millimeter-sized abnormalities in brain tissue that may cause unpredictable seizures. These 'microlesions' could lead to spontaneous electrical currents causing epilepsy.
African Americans and Hispanics are less likely to receive effective radiation therapy for early-stage lung cancer, according to a study. The study highlights significant disparities in treatment options based on hospital type and insurance status.
Researchers have discovered that growth factor VEGF-B can regenerate damaged peripheral nerves in the cornea without inducing angiogenesis. This finding suggests that VEGF-B may be a suitable candidate to treat nerve damage in areas where blood vessel formation would be detrimental.
The SENSEI Instrument project aims to create a camera system that captures the entire surrounding environment, including the size and mass of objects. This technology will provide detailed information on marine life, such as coral reefs and kelp forests, and enhance our understanding of cultural heritage sites.
A federal prescription-subsidy program improved adherence to hormone therapy among low-income women with breast cancer. The program's success was attributed to lower out-of-pocket costs, which reduced disparities in adherence rates across racial and ethnic groups.
The University of Illinois Chicago has established a new Research and Training Center to study the experiences of family caregivers caring for people with disabilities. The center aims to improve the health and well-being of individuals with disabilities and their families by understanding their needs and challenges.
Researchers found that oleate, a common dietary fat, restored proper metabolism of fuel in an animal model of heart failure. This improvement enabled the heart muscle to access energy more efficiently and reduced toxic fatty byproducts.
Researchers discovered a way to boost sensitivity of graphene-based sensors by exploiting the unique electronic properties of grain boundaries. By analyzing these imperfections, scientists created an 'electronic nose' that can detect single gas molecules, revolutionizing chemical sensing applications.
Researchers found that bexarotene reduces amyloid-beta levels in late-stage Alzheimer's mice but increases them in early stages. This study suggests a personalized treatment approach for APOE4 carriers, who may benefit from short-term treatment in later disease stages.
A team of researchers at the University of Illinois Chicago has identified a single receptor, TLR5, that triggers inflammation and bone degradation in rheumatoid arthritis. Blocking this receptor may provide a new therapeutic target to interrupt the disease's vicious cycle.
Researchers discovered two potential therapeutic targets to treat pulmonary arterial hypertension, a deadly disease marked by high blood pressure in the lungs. The targets involve suppressing abnormal proliferation of smooth muscle cells and signaling molecules involved in the disease.
Researchers have found that magnetite nanocubes can form chiral helices when exposed to an external magnetic field. The helices are formed through a balance of competing forces, including the Zeeman force and dipole-dipole magnetic force.
Researchers at the University of Illinois Chicago discovered hyper-connected emotional and cognitive networks in the brains of young adults who had previously experienced depression. These hyper-connectivities were related to rumination, a maladaptive strategy that can lead to depression and relapse.
Researchers have synthesized a catalyst that improves their system for converting waste carbon dioxide into syngas, a precursor of gasoline and other energy-rich products. The new catalyst uses molybdenum disulfide and an ionic liquid to reduce carbon dioxide in a chemical reaction, improving efficiency and lowering cost.
Scientists have identified the underlying force of magnetism as the key to high-temperature superconductivity in cerium, cobalt, and indium. By analyzing experimental data using a novel theoretical framework, researchers successfully predicted the material's superconducting properties.
A study of over 3,000 Kenyan men found that male circumcision significantly reduces the risk of acquiring HIV without leading to increased promiscuity or decreased condom use. Despite an initial increase in sexual activity, all other risky behaviors declined and condom use increased across both circumcised and uncircumcised groups.
Researchers found that bexarotene reduces levels of neurotoxic protein amyloid-beta in mice with late-stage Alzheimer's, but increases it during early stages. This suggests that treatment timing and duration may be crucial for effectiveness.
Researchers discovered cholesterol's activation of a signaling pathway linked to cancer growth and division. Elevated cholesterol levels may selectively promote cancerous pathways, providing a new mechanism for cancer risk.
Researchers discovered how a protein molecule in immune cells promotes nitric oxide production, a potent weapon against bacterial attack. The discovery highlights the importance of finding a balance between fighting infection and preventing tissue damage.
A study found that adults are heavily exposed to e-cigarette marketing through various media channels, including TV and online platforms. E-cigarette users were more likely than non-users to search for information on Facebook and share it with others.
Researchers analyzed over 70,000 tweets about e-cigarettes and found nearly 90% were commercial ads promoting e-cig products. The study highlights the risks of social media platforms like Twitter in advertising e-cigarettes to youth, which may lead to increased use and smoking cessation.
A study by University of Illinois Chicago found that patients with alcohol in their blood had a reduced risk of developing cardiac and renal complications, resulting in lower mortality rates. The protective effect was observed even after the alcohol was metabolized.
Pediatricians face financial and data risks due to ICD-10 code conversions. Researchers found 26% of pediatric ICD-9 codes have complex mappings, potentially causing reimbursement issues and lost clinical information.
A new supersonic spray system produces a smooth, defect-free graphene layer by dispersing and restructuring graphene flakes. This method enables the production of high-quality graphene on various substrates without post-treatment or introducing defects.
Researchers discovered that CCL28 and its receptor are key players in angiogenesis, a hallmark of rheumatoid arthritis. This finding provides strong evidence for the binding of CCL28 to joint-lining cells as necessary for blood vessel formation.
Researchers at the University of Illinois Chicago have discovered a protein molecule that slows the progression of pulmonary fibrosis, a deadly lung disease. The protein, LYCAT, is found to be protective and may boost survival rates in patients with idiopathic pulmonary fibrosis.
A study by researchers at the University of Illinois Chicago found that massage therapy improves systemic circulation and alleviates muscle soreness after exercise. The study also showed that massage has benefits for people regardless of their level of physical activity, improving vascular function in healthy sedentary adults.
The university will fund research, training, and education projects to address health disparities in this population. The center's Health Matters program has developed evidence-based tools, including peer mentoring and online resources, to promote healthy behaviors.
Researchers found that low-intensity vibration can accelerate wound healing in mice with diabetes by forming more granulation tissue and new blood vessels. The study suggests that this non-invasive technique could be easily translated to humans and is being tested in human trials.
A UIC chemistry professor has been awarded a prestigious international sustainability grant to lead the US effort in developing novel catalytic methods. The project aims to replace rare metals with inexpensive and abundant metals, reducing environmental pollution and resource depletion.
Researchers at the University of Illinois Chicago have developed a computerized treadmill program to prevent falls in older adults. Studies show that people can be trained not to fall, with adaptations retained for up to 12 months. The training is safe even for those with reduced bone density or osteoporosis.
Caucasians 55+ are at greatest risk of a deadly lung infection caused by nontuberculous mycobacteria (NTM), which affects over 2,990 people in the US each year. The infection is treatable but expensive antibiotic therapy can take up to two years.
A new study aims to improve patients' ability to walk after a stroke by combining brain stimulation with gait training. The treatment group will receive transcranial direct current stimulation before gait training to help restore balance in cortical excitability.
A recent study found that the ICD-10 transition led to significant information loss, affecting about 8 percent of Medicaid codes. Financial implications also emerged, with 39 codes accounting for 2.9 percent of total Medicaid reimbursements and 5.3 percent of UI Cancer Center billing charges.
A national survey of primary care physicians found they often experience uncertainty in ordering and interpreting clinical laboratory tests, with missing results and confusing report formats being major challenges. Physicians reported that improved electronic decision-support tools and access to lab personnel would help reduce this unc...
Patients who received assistance from poison centers had shorter hospital stays and lower hospital charges. The study found a cumulative decrease of $2,078 in hospital charges per 10 patients.
Scientists created nanoparticles that selectively bind to abnormal immune cells causing inflammation, allowing anti-inflammatory drugs to reach them while leaving healthy ones untouched. This targeted approach shows promise for treating inflammatory diseases with fewer side effects.
The trial will examine effectiveness of different doses of inhaled corticosteroids with or without long-acting beta agonists in 500 African American patients aged 5 and older. Researchers aim to identify the most effective combination of medications and dosing regimens to manage asthma symptoms.
Researchers at the University of Illinois Chicago have developed a graphene 'sandwich' that enables atomic-level imaging of biomolecules in their natural state. This breakthrough improves resolution and minimizes damage to samples, opening up analysis of difficult-to-image biological samples.