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University of Liverpool


Review seeks to understand and manage risk factors for common heart condition

A large-scale review published in The Lancet Regional Health Europe provides an update on the recent advances in understanding and managing risk factors for atrial fibrillation (AF). AF affects around 1.4 million people in the UK, causing irregular heart rates and impairing quality of life. Researchers found that a more individualized ...

SourceUniversity of Liverpool·JournalThe Lancet Regional Health - Europe·TypeMeta-analysis·DateFeb 22, 2024

Study identifies increase in antibiotic-resistant typhoid

Researchers found an association between the number of ciprofloxacin prescriptions and the emergence of antibiotic-resistant S. Typhi isolates with QRDR mutations. The study suggests that increased antimicrobial use contributed to the emergence of resistance, highlighting the need for better diagnostics and vaccines.

SourceUniversity of Liverpool·JournalThe Lancet Microbe·TypeObservational study·DateFeb 19, 2024

Study demonstrates potency of synthetic antibiotic against serious chronic infections

A new synthetic antibiotic teixobactin has been shown to be highly effective against 'superbugs' such as MRSA and bacterial biofilms, which are associated with serious chronic infections. The study's findings provide promising hope for the development of new treatments against multidrug-resistant bacteria and biofilm-related infections.

SourceUniversity of Liverpool·JournalEuropean Journal of Medicinal Chemistry·DateJan 3, 2024

Liverpool begins first human trial of new Zika vaccine

The University of Liverpool is conducting a Phase I trial of a new Zika virus vaccine designed for pregnant women, which has shown promising results in animal studies. The vaccine aims to generate highly protective and long-lasting immunity against the mosquito-borne virus that can cause severe foetal birth defects.

SourceUniversity of Liverpool·TypeRandomized controlled/clinical trial·DateApr 27, 2023

Discovery of T-cells that protect against deadly pneumococcal disease

A study by University of Liverpool researchers reveals how a unique subset of lung T regulatory cells provide resistance to bacteraemic pneumonia. These cells, known as TNFR2 expressing Tregs, play a critical role in maintaining and controlling frontline host immune responses when pneumococci infect the lungs. The findings have signifi...

SourceUniversity of Liverpool·JournalCell Reports·TypeExperimental study·DateFeb 8, 2023

Immunocompromised patients remain at higher risk of COVID-19 death in hospital

A UK study using data from over 150,000 hospitalized patients found that immunocompromised individuals had a 44% higher risk of death compared to those with normal immune systems. The gap in mortality rates widened for immunocompromised patients over time, highlighting the need for targeted interventions such as antiviral treatments an...

SourceUniversity of Liverpool·JournalPLOS Medicine·TypeData/statistical analysis·DateFeb 1, 2023