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University of Queensland


Zinc discovery holds promise for people with cystic fibrosis

Researchers at University of Queensland have discovered a zinc pathway defect in immune cells of people with cystic fibrosis, leading to increased susceptibility to bacterial infections. The team identified a potential solution by restoring the macrophages' ability to kill bacteria with a zinc transport protein.

SourceUniversity of Queensland·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateFeb 22, 2024

Revealing what makes bacteria life-threatening

Scientists found a mutation in E. coli that allows it to spread further into the body and infect organs, causing life-threatening diseases. The discovery helps explain why certain types of E. coli become more dangerous and provides an explanation for emerging virulent bacteria.

SourceUniversity of Queensland·JournalNature Communications·TypeExperimental study·DateFeb 21, 2024

Mapping potential pathways to MND treatment

Scientists have mapped out the proteins involved in motor neurone disease (MND) across its trajectory, identifying potential therapeutic pathways for further investigation. The study found that a protein-folding factor called DNAJB5 is elevated early on in MND, sparking curiosity about its role in disease progression.

SourceUniversity of Queensland·JournalNature Communications·TypeExperimental study·DateFeb 19, 2024

Fatty acids hold clue to creating memories

Researchers have identified the molecular mechanism behind memory creation and found that saturated fatty acids interact with a protein called STXBP1. This interaction coordinates the release of fatty acids and directs communication at synapses in the brain.

SourceUniversity of Queensland·JournalThe EMBO Journal·TypeExperimental study·DateFeb 5, 2024

Spider venom heart drug a step closer

A University of Queensland team has developed a spider venom molecule, Hi1a, that protects cells from heart attack and stroke damage. The drug candidate has passed critical benchmarks in preclinical tests, which indicate it could be an effective therapeutic with reduced side effects.

SourceUniversity of Queensland·JournalEuropean Heart Journal·TypeExperimental study·DateJan 16, 2024

Coral reefs in peril from record-breaking ocean heat

A recent study by University of Queensland scientist Professor Ove Hoegh-Guldberg warns that record-breaking marine heatwaves will cause catastrophic mass coral bleaching worldwide. The research suggests that current marine heatwaves will likely lead to a global mass coral bleaching event over the next 12-24 months.

SourceUniversity of Queensland·JournalScience·TypeMeta-analysis·DateDec 8, 2023

A patch of protection against Zika virus

A new vaccine patch has delivered an effective immune response to Zika virus in mice, providing rapid protection against the disease. The patch, which uses a high-density microarray platform, targets a specific protein crucial to the virus's survival and evokes T-cell responses up to 270% higher than traditional vaccines.

SourceUniversity of Queensland·JournalMolecular Therapy — Nucleic Acids·DateNov 30, 2023

Researchers discover new classes of RNA for learning and memory

Researchers from the University of Queensland have identified a noncoding RNA called Gas5 that coordinates neuronal excitability in real time, contributing to learning and memory. The study found that this RNA is uniquely required for fear extinction memory, a type of critical input processing that leads to the formation of memory.

SourceUniversity of Queensland·JournalNature Communications·TypeExperimental study·DateNov 29, 2023

Social media helping to protect biodiversity

Researchers have successfully mapped thousands of animal species in Bangladesh using social media posts, significantly improving habitat conservation. The study also highlights opportunities for social media companies to automate biodiversity data collection, making it easier for scientists to access and utilize.

SourceUniversity of Queensland·JournalOne Earth·DateNov 16, 2023

Genetics links endometriosis and IBS

A study published in Cell Reports Medicine reveals that endometriosis and irritable bowel syndrome (IBS) share common genetic risk factors. This finding explains why patients with one condition may also develop the other, highlighting the need for increased awareness and early diagnosis.

SourceUniversity of Queensland·JournalCell Reports Medicine·TypeData/statistical analysis·DateOct 26, 2023

Killing remains a threat to Bornean orangutans

Research reveals that the illegal killing of orangutans on Borneo remains a significant threat to the species, with 30% of villages reporting killings in the last 5-10 years. Conservation efforts may not be effectively preventing killing and addressing human-orangutan conflict is crucial.

SourceUniversity of Queensland·JournalConservation Science and Practice·TypeSurvey·DateOct 10, 2023

Potential genetic screening for aggressive melanoma

Researchers from The University of Queensland and The Alfred hospital in Melbourne have identified gene variants associated with a higher risk of nodular melanoma. The study found that four genes with rare DNA variants were linked to the aggressive subtype, which accounts for most melanoma deaths.

SourceUniversity of Queensland·JournalBritish Journal of Dermatology·TypeObservational study·DateOct 3, 2023

New target to beat cancer drug resistance

University of Queensland researchers have identified a novel molecule that could overcome cancer drug resistance and prevent tumour regrowth in cancer patients. The newly discovered molecule is not currently a target for treatment, opening the potential for new drug development to combat this major cause of death in cancer patients.

SourceUniversity of Queensland·JournalDrug Resistance Updates·TypeExperimental study·DateSep 21, 2023

Half the population to have a mental health disorder by 75

A global study led by researchers from the University of Queensland and Harvard Medical School found that one in two people will develop a mental health disorder in their lifetime. The study analyzed data from over 150,000 adults across 29 countries and found that 50% of the population develops at least one disorder by age 75.

SourceUniversity of Queensland·JournalThe Lancet Psychiatry·TypeMeta-analysis·DateJul 30, 2023

New antibiotics on the way – but not quickly enough

A report from University of Queensland researchers highlights promising developments in new antibiotics, with 62 in development. However, experts warn that current pace is not enough to avoid a crisis due to rising deaths from resistant bacteria, with potential solutions including subscription payment models and non-antibiotic approaches.

SourceUniversity of Queensland·JournalThe Journal of Antibiotics·TypeLiterature review·DateJul 24, 2023

How an unlikely amphibian survived its “Judgement Day”

Researchers discovered unprecedented snake venom resistance in caecilians, highlighting the species' ability to evolve under severe selective pressure. The study found that caecilians deployed three distinct biological methods to resist elapid snake venom, including changing receptor shape and deploying an electromagnetic 'weapon'.

SourceUniversity of Queensland·JournalInternational Journal of Molecular Sciences·DateJul 23, 2023

Science language barrier could cost countless careers

A University of Queensland-led survey found non-native English speakers need up to twice as much time to conduct scientific activities, with papers rejected two-and-a-half times more. The study highlights the challenges faced by non-native English speakers in academia, which can lead to stagnated careers and a loss of potential contrib...

SourceUniversity of Queensland·JournalPLOS Biology·DateJul 18, 2023

Developer dollars not enough to save species

Research found that financial payments by developers to compensate for environmental consequences are insufficient to achieve intended outcomes. Only 0.7 of 13.4 hectares of impacts on koala habitat have been offset through financial payments since 2018, raising concerns about the future of this endangered species.

SourceUniversity of Queensland·JournalPeople and Nature·DateJul 9, 2023

Lasering lava to forecast volcanic eruptions

University of Queensland researchers have developed a new technique using laser ablation inductively coupled plasma quadruple mass spectrometry to analyze the chemical composition of magma. This high-resolution method provides clearer data on the eruption style and lava flow, enabling better forecasting of volcanic eruptions.

SourceUniversity of Queensland·JournalScience Advances·DateJul 5, 2023

Rising monkey and pig populations pose human disease risk

Researchers warn that exploding wild pig and macaque populations in Southeast Asia pose significant zoonotic disease risks to humans. The study, led by the University of Queensland, found that these animals can carry diseases that can be transmitted to people, highlighting the need for urgent management solutions.

SourceUniversity of Queensland·JournalBiological Reviews·TypeObservational study·DateJun 29, 2023

New venom discovery from deadly cone snails

Researchers discovered crucial differences in venoms across the lifecycle of cone snails, using a new laboratory aquarium system to study juvenile stages. The findings reveal unique adaptations for hunting and venom composition, offering potential new drugs for pain medication and disease treatment.

SourceUniversity of Queensland·JournalNature Communications·TypeObservational study·DateJun 27, 2023