Researchers from the University of Queensland have successfully grown native wild tobacco plants as 'biofactories' to produce large quantities of drugs. The method uses modern molecular biology techniques to instruct plant cells to produce desired molecules, resulting in a more cost-effective and sustainable production process.
Researchers have discovered how Botox, a deadly neurotoxin, enters brain cells, allowing for potential therapeutic targets to be identified. The study, published in the EMBO Journal, reveals that Botox hijacks a complex of receptors to interrupt communication between nerves and muscle cells, causing paralysis.
Researchers discovered vitamin D's role in regulating dopaminergic neuron differentiation and function. The study found that vitamin D alters developing neurons in the brain's dopamine circuit.
Researchers discovered that marsupial brains exhibit region-specific patterns of cortical activity during early development. This finding provides valuable information about human brain development and may inform strategies for improving cognitive function in humans.
Research reveals liver cells play a crucial role in regulating the body's internal circadian clock, influencing sleep patterns, hormone secretion, and metabolism. Studies on mice with humanized livers show that altered liver function can disrupt circadian rhythms, highlighting potential new treatments for metabolic diseases.
A team of researchers used artificial intelligence to create a 3D model of the Commander complex, a bundle of proteins that transport proteins in cells. This has helped understand how mutations cause disease, including Alzheimer's and heart disease.
Researchers have found sedimentary archives in sand dunes that can reconstruct reliable, multi-millennial fire histories. The discovery aims to expand scientific understanding of fire regimes around the world and uncover the role of humans on fire history.
Researchers found that humpback whales have a unique response to wind noise, singing louder in noisy conditions. In contrast, they do not exhibit an increased reaction to vessel noise from boats. This finding has implications for understanding whale behavior and potential consequences for breeding practices.
Self-directed ageism is common among older people due to internalized ageist beliefs, which can lead to decreased lifespan, poorer health, and reduced confidence. Interventions like positive social interactions between younger and older adults may help prevent negative views of ageing.
Researchers at University of Queensland have identified a novel pain pathway triggered by the Gympie-Gympie tree's toxins, which could lead to non-opioid pain relief. The gympietide toxin interacts with nerves after injection through fine needle-like hairs on the leaves and requires a partner protein called TMEM233 to function.
Researchers have discovered that most immune cells contributing to chronic inflammation in severe COVID-19 are not infected with the SARS-CoV-2 virus. Instead, these uninfected macrophages detect damage and trigger a strong inflammatory response, leading to excessive collateral damage.
Researchers have developed a cubic molecule platform that can improve the properties of hydrocarbons like cubane, which was previously overlooked due to limited synthesis. This breakthrough enables the incorporation of nitrogen atoms, facilitating biologically desirable interactions and expanding options for chemists.
Researchers have discovered new targets for developing antibiotics to combat sepsis, a leading cause of death worldwide. The study provides valuable insights into how different bacterial species respond to infection and could lead to more effective treatments.
Researchers discovered that as magma production decreased, volcanoes became increasingly complex, with internal magma pockets and reservoirs forming. The study provides insights into volcanic eruption processes and can inform our understanding of active continental hotspot volcanoes globally.
A worldwide study found that non-English-language literature was extensively used in national reports but failed to be reflected in global reports. The team suggests that international collaboration and multilingual databases can help develop more effective conservation science.
Researchers identified a gene linked to Parkinson's Disease also contributes to cell debris buildup in the brain. Autophagy disruption leads to toxic waste accumulation and neuron death, hallmarks of the disease. The discovery could pave the way for new, more effective treatments by targeting autophagy.
A University of Queensland-led research team is using an unusual caesium atom to search for dark matter particles. The team's work may also improve atomic theory calculations and technology, such as navigation systems.
Researchers have identified critical areas in northern, northwestern, and western Iran for urgent conservation action. The study used maps of threatened species to pinpoint regions necessary to protect critically endangered species like the Asiatic cheetah and Persian leopard.
Researchers from the University of Queensland found that humpback whales have shifted their mating behaviour, with males giving up singing and instead fighting for dominance. This change is believed to be due to the increased population size after whaling cessation, as larger groups may deter other males from approaching potential mates.
A University of Queensland study found that snakes can hear airborne sound and react to it, contrary to popular belief. The research used soundproof rooms and observed reactions from captive-bred snakes, revealing differences in responses based on genus and evolutionary pressures.
A University of Queensland-led team has secured almost $8 million in philanthropic funding to develop an mRNA vaccine against Group A Streptococcus (Strep A), which causes over 500,000 deaths annually due to rheumatic heart disease.
Researchers from The University of Queensland have identified new active compounds in Hericium erinaceus that promote neuron projections, extending and connecting to other neurons. This discovery could lead to treatments and protection against neurodegenerative cognitive disorders such as Alzheimer's disease.
Researchers at the University of Queensland discovered two distinct processes in the human brain when exposed to prolonged or repeated sensory inputs. These findings could provide clues for understanding and treating sensory brain disorders.
Expanding seaweed farming could reduce demand for terrestrial crops and greenhouse gas emissions by up to 2.6 billion tonnes per year. The study identified millions of available hectares of ocean suitable for farming, with the Indonesian EEZ showing great potential.
Researchers at the Queensland Brain Institute developed a new ultrafast fMRI technique to study brain activity. The technique revealed that brain activity follows preferential circuits depending on cell type organisation, and blood signals can reflect network organisation and cell type distribution.
Research by University of Queensland finds that the Environment Protection and Biodiversity Conservation Act is not effectively protecting threatened habitats. Projects deemed 'significant' or 'not significant' have resulted in similar habitat destruction, highlighting inconsistencies in referral decision-making processes.
Researchers from the University of Queensland created a detailed outline of the cuttlefish brain structure and neuronal network, shedding light on their camouflage abilities. The study reveals that the cuttlefish's brain adaptations reflect their daily life requirements and ecology.
The Australian black swan's genetic makeup makes it highly susceptible to viral illnesses like avian flu. Without common immune genes found in other waterfowl, the species is at risk of decimation if HPAI enters its native habitat.
Researchers have discovered a pathway in cells that could be used to reprogram the body's immune system to fight chronic inflammatory and infectious diseases. A molecule derived from glucose, ribulose-5-phosphate, has been found to stop bacteria from growing and dampen inflammatory responses.
University of Queensland researchers have found a way to more efficiently convert sugarcane into isobutanol, a chemical used in fuels, plastics, and food additives. The cell-free method produces at least 10 times the amount of isobutanol as traditional methods, offering higher yields and more control over the production process.
A research team from the University of Queensland has developed a tool to guide the global beef industry in reducing costs and greenhouse gas emissions. The study found that as much as 85% of emissions could be cut without an overall economic hit, by opting for more efficient feeds and locations.
Scientists create an artificial brain in a petri dish to study the effects of the Zika virus. The study reveals that viral noncoding RNA helps the virus evade antiviral responses and cause cell death in developing brains.
A University of Queensland study analyzing almost three million chess moves found that wearing a mask reduces the average quality of player decisions due to annoyance caused by the masks. The effect subsides after four to six hours of playing, suggesting mask-wearing impact depends on task type and duration.
A new, non-invasive malaria detection tool developed by a University of Queensland-led team can quickly identify entire villages or towns suffering from the disease. The device uses infrared-light and is chemical-free, needle-free, and detects malaria through the skin.
Researchers used satellites with radar imaging sensors to map flooding and assess flood impacts in Queensland. The technique combines images from optical satellites with information from imaging radar satellites, providing faster update times and more accurate data.
A University of Queensland-led research group has created the world's first successful donkey embryo using in-vitro fertilisation (IVF), which could save dozens of endangered donkey species. The team used a specialist IVF process known as intracytoplasmic sperm injection (ICSI) to create the viable embryo.
A team of researchers used AI pattern recognition to re-analyze footprints from the Dinosaur Stampede National Monument and concluded that they were made by an ornithopod dinosaur, a herbivorous species. The results contradicted the long-held assumption of a vicious dinosaur predator.
Researchers at UQ's Queensland Brain Institute found a causal relationship between lack of oxygen to the brain during sleep and Alzheimer's disease in mice. CPAP treatment for obstructive sleep apnea may prevent cognitive impairment and neuron death, reducing dementia risk.
Researchers discovered Fyn enzyme clusters when immobilized in synapses, forming toxic 'protein clumps' linked to dementia. Targeting Tau biomolecular condensates may prevent dementia progression.
Researchers from the University of Queensland found that having more babies reduces a woman's risk of endometrial cancer by 50% compared to none. The study used genetic analysis and examined how many years women ovulated, with strong links pointing to childbirth.
Research found COVID-19 activates inflammatory response in the brain similar to Parkinson's disease, potentially leading to neurodegenerative conditions and new treatment approach with UQ-developed inhibitory drugs
Researchers at the University of Queensland have confirmed black hole quantum properties, including superposition and wildly different masses simultaneously. The study reinforces early theories by Jacob Bekenstein, postulating that black holes can only have specific mass values within certain bands or ratios.
A University of Queensland study analyzed tree ring data to understand cosmic radiation 'storms', known as Miyake Events. The research suggests that these events are not correlated with sunspot activity and may be a kind of astrophysical 'storm' or outburst.
Sharing real-time air quality readings can reduce fine particulate concentration levels by 2-4 micrograms per cubic metre each year, leading to significant health benefits. The research estimates annual health benefits of $171 million AUD for the median city.
Researchers found four species – tigers, elephants, wild boars, and clouded leopards – showing increased populations in areas with human infrastructure. However, deforestation still impacted some species, particularly clouded leopards.
A study by the University of Queensland found that 65% of childcare centers in rural areas provide meals, while those in disadvantaged communities face significant challenges. The provision of high-quality food is essential for children's learning and development, yet many families struggle to afford nutritious meals.
The study found that human neocortical pyramidal neurons have a more elaborate structure than other mammals, with larger and more complex dendritic trees. This enhancement may contribute to the brain's increased processing power. The research has implications for understanding how the brain is affected in diseases such as epilepsy.
Researchers have analyzed data from 5.4 million people to uncover 12,000 genetic variants influencing height, explaining 40% of differences. This breakthrough enables the prediction of height with greater accuracy, particularly for children, and has implications for medical investigation and police investigations.
A University of Queensland study reveals low-income Brisbane suburbs have significantly fewer trees than middle- and higher-income areas, leaving residents vulnerable to the effects of climate change. The research highlights the need for increased investment in tree planting to address this environmental inequity.
University of Queensland researchers have discovered metal compounds with antifungal properties, showing promise in developing new treatments for resistant fungal infections. The study found that one in five metal compounds displayed activity, with low toxicity in preliminary tests.