A nasal spray flu vaccine candidate developed by UW–Madison researchers has shown safety and potential to bolster protection against seasonal and pandemic influenza in vulnerable individuals. Administered alongside the annual flu shot, the vaccine may provide better protection for seniors.
Researchers found remarkably low concentrations of beryllium-10 and carbon-14 in glacier bedrock, suggesting melting ice exposed bedrock for the first time recently. This suggests tropical glaciers are shrinking beyond what's been seen in recent geologic past, foreshadowing climate's effect on global ice.
Researchers identify key steps in Pseudogymnoascus destructans infection, including epidermal growth factor receptor co-optation and manipulation of keratinocytes. The discovery opens potential treatment possibilities using FDA-approved drug gefitinib.
A new study suggests that exposure to raw milk infected with the currently circulating H5N1 virus poses a significant risk to humans. However, the virus may not spread very far or quickly to others, as experiments on mice and ferrets show limited airborne transmission.
Researchers at the University of Wisconsin-Madison have developed a new method to treat cancer using T cells, which was discovered by chance. The two-step process 'metabolically priming' enhances the ability of T cells to target tumors and survive longer in the body.
Researchers developed low-cost, real-time sensors that can monitor nitrate in soil, enabling farmers to make informed decisions on fertilizer usage. The sensors have been tested in various soil types and showed accurate results.
Researchers found that wolves on Isle Royale initially affected foxes and martens by altering their habitats and diets. However, as the wolves formed packs, the effects on these carnivores disappeared. Interestingly, human visitors had a more significant impact on these species interactions than the reintroduced wolves.
Researchers discovered wind from a black hole's radiation blasting gas out of its galaxy at an unprecedented speed. The study sheds light on how active black holes shape their galaxies by spurting on or snuffing out new star formation.
Astronomers have discovered a sulfurous atmosphere on the smallest and coldest exoplanet known, providing clues to its formation process. The planet's unique orbit and composition offer insights into how planets are created.
The UW–Madison team developed a label-free method to observe individual molecules using an optical microresonator, allowing for the detection of molecules with unprecedented sensitivity. This breakthrough has potential applications in drug discovery and advanced materials development.
A new study reveals that nearly 30 million acres of abandoned US cropland could be used to grow crops and trap carbon dioxide from the atmosphere. The researchers mapped the lands at field-level resolution, providing valuable insights into their potential for sustainable energy production.
Researchers at the University of Wisconsin-Madison have developed a novel approach to treating pancreatic cancer using nano-drugs delivered via bacteria. The treatment bypasses the dense collagen barrier surrounding tumors, allowing for more effective delivery of immunotherapies.
Researchers at UW–Madison developed a method using short electric pulses to increase gene therapy material uptake in liver cells, reducing dosage needed. The technique could help treat genetic diseases like cystic fibrosis and sickle-cell disease.
A new nanomaterial has been developed to mimic the behavior of proteins and may lead to effective treatments for Alzheimer's and other neurodegenerative diseases. The nanomaterial alters the interaction between two key proteins in brain cells, potentially providing a powerful therapeutic effect.
Researchers mapped over 1,000 yeast species to understand their genetic blueprints and evolutionary history. The results suggest that internal factors are the primary drivers of variation in a yeast's ability to eat different foods.
Researchers mapped the evolution of a specific regulatory protein over millennia, revealing a novel pattern where function gain and loss occur rapidly. This study may reveal similar patterns in other regulatory proteins, enabling new discoveries in biomedical and biotechnological applications.
Researchers developed a new tool to study adult neural stem cells, identifying their dormant state and behavior. By analyzing autofluorescence signatures, they can study the aging process and neurological diseases.
The sequencing of the blue whale and Etruscan shrew genomes has provided significant insights into developmental biology, with the largest mammal showing a surprisingly slow developmental clock. The study also sheds light on metabolism, with the tiny shrew serving as a model for understanding high-energy demands.
Scientists have developed a new model to accurately understand methane emissions in the region, finding that wetlands are producing more methane over time. This is due to the warming of these biomes, causing the stored carbon to be released into the atmosphere as methane, contributing to global warming.
A new study reveals that walleye are struggling to survive in warming waters of the Midwestern United States and Canada. Climate change is disrupting the historical pairing of ice-off and walleye spawning, which threatens the persistence of walleye populations across the Upper Midwest.
Researchers at UW-Madison have developed a groundbreaking method for 3D printing functional human brain tissue, which can grow and function like typical brain tissue. The printed cells form connections, send signals, and interact with each other through neurotransmitters, mimicking the complexity of human brains.
Researchers found that participants who were initially skeptical or disagreed with climate change or BLM became more supportive after conversing with GPT-3. The chatbot's response styles differed between topics, with more justification for human-caused climate change.
A recent study from the University of Wisconsin School of Veterinary Medicine has uncovered new information about orofacial development in mice that researchers believe could one day help reduce the risk of these birth defects in humans. DNA methylation is a process where molecules are added to DNA that change gene expression without a...
A study published in Applied Animal Behaviour Science found that dogs are most engaged when watching videos featuring other animals, with content featuring other dogs being the most popular. The research aims to improve the assessment of canine vision and support a healthier life for dogs as they age.
Scientists have discovered an Earth-sized planet in our solar backyard that may be similar to early Earth due to its proximity to the Sun and crowded system. The newly discovered planet was identified using the Transiting Exoplanet Survey Satellite (TESS) and is part of a young star system called the Ursa Major Moving Group.
Researchers used cell imaging and genome editing technology to study the Coat Protein Complex II, a critical group of proteins that transport proteins within cells. They discovered that Sec23 helps restore COPII's function after disruption, with potential implications for diseases like cancer and Type 2 diabetes.
Researchers developed a new lightweight foam material that can dissipate an enormous amount of rotational kinetic energy from an impact, potentially preventing traumatic brain injuries. The material is 30 times better at absorbing shear strain than current foams used in military combat helmet liners.
Scientists are finding that risk factors for autism spectrum disorder boil down to a couple of core pathways in early human brain development, according to researchers using technologies like RosetteArray. This new understanding is helping identify potential targets for treatments.
Researchers engineered bacteria to produce zeaxanthin and PDC simultaneously from underutilized plant fiber, offering a promising solution for sustainable biofuels. The discovery could lead to lower greenhouse gas emissions and improved economics in the production process.
Researchers have developed a mineral coating that maintains mRNA activity for up to six months at room temperature. This breakthrough enables the storage of mRNA therapeutics like COVID-19 vaccines on medical shelves, bridging the gap between rich and poor communities.
Researchers at UW-Madison created a new material that can absorb and trap hydrogen particles, protecting fusion reactor walls from damage. The cold spray coating technology uses tantalum to create a surface that can regenerate itself by expelling trapped hydrogen.
Researchers at UW-Madison have developed a new electrochemical method to extract ammonia and potassium from livestock manure, reducing pollution and producing valuable fertilizers. The technique shows promise in scaling up beyond proof-of-concept stage.
A new study from the University of Wisconsin-Madison found that individuals born in dry counties due to Prohibition-era laws lived longer, with an average additional lifespan of approximately 1.7 years. This increase in longevity is equivalent to nearly 15% of the overall life expectancy improvements for those born between 1900-1930.
Researchers analyzed Antarctic sediment records to understand past ice sheet behavior, finding frequent and rapid growth and recession cycles over thousands of years. The study suggests that climate factors beyond Earth's orbit may trigger these changes, potentially leading to unexpected ice sheet dynamics in the coming centuries.
A new study found that COVID-19 caused a significant spike in premature births, but vaccines played a crucial role in reducing the risk of preterm birth to pre-pandemic levels. The research analyzed California birth records and found that maternal COVID infection increased the risk of preterm births by 1.2 percentage points.
A study found that children with unpredictable parental support tend to avoid exploratory risks, even in games designed to encourage them. This self-imposed limit on risk is not related to stress or anxiety levels, but rather a brain response to uncertainty, where familiar options are preferred over potentially uncertain outcomes.
A new study from the University of Wisconsin-Madison suggests that reducing isoleucine intake can extend lifespan and improve health outcomes. Mice on a low-isoleucine diet lived 33% longer and showed better health markers than those on a balanced diet.
Two new UW–Madison-led studies examine the growth of carbon removal technologies, finding that they need to scale faster to meet policy targets. The research analyzes historical data and modeling scenarios to inform the required rate of adoption for novel carbon removal methods.
Researchers at the University of Wisconsin-Madison have successfully generated human norepinephrine neurons from stem cells using a key protein called ACTIVIN-A. These LC-NE neurons may serve as models for disease in humans, enabling scientists to screen drugs and answer questions about neurodegeneration.
A study from the University of Wisconsin-Madison and Academia Sinica of Taiwan has successfully combined lab-grown cardiomyocytes with stem-cell-derived endothelial cells to regenerate damaged heart muscle after a heart attack. This combination therapy holds promise for tackling arrhythmia and could lead to improved clinical applications.
New study reveals that microtubule poisons effectively treat cancer by causing abnormal cell division, leading to tumor cell death. The findings contradict decades-long assumptions about the mechanism of action of these drugs.
Researchers analyzed DNA from 200-year-old fruit flies collected in Europe, revealing their surprising genetic similarity to modern flies. The study identified key genes that helped the flies adapt to changing environments, including a gene resistant to DDT pesticide.
A recent study from University of Wisconsin-Madison researcher Max Besbris found that non-Spanish speaking Americans perceive Spanish housing ads as indicative of less desirable housing options, leading to racial segregation. The study suggests that language in online rental housing advertisements shapes people's perceptions of their p...
Researchers at UW-Madison discovered that FMRP regulates mitochondrial function in human brain cells even before birth, leading to a potential treatment for FXS. The study suggests that FMRP plays a critical role in prenatal development and may be linked to autism spectrum disorder.
Researchers have discovered that midbody remnants, thought to be cellular trash, contain working genetic material that can change the fate of other cells, including turning them into cancer. The study suggests that these remnants may play a key role in spreading cancer throughout the body.
A machine learning algorithm identified patterns in citations to prioritize important contributions, revealing NIH-funded basic science accounts for 30% of substantive research. Federal funding for basic research is crucial for stimulating clinical research, according to the analysis.
A team at UW–Madison has compiled 270 combinations of molecules with the potential for sustained autocatalysis, focusing on comproportionation reactions. This cookbook-like approach may help identify conditions for life elsewhere in the universe, guiding future research.
Researchers at UW–Madison and Stanford University developed a new approach to increase donor and recipient biocompatibility, inducing tolerance in transplanted kidneys. Two monkeys with just one match among key protein strings maintained chimeric immune systems for over four years without rejection or graft-versus-host disease.
Rivers and streams worldwide emit substantial amounts of methane, with human activity playing a primary role in controlling these emissions. The study's findings suggest that conservation and restoration efforts could reduce methane production, improving climate change dynamics.
University of Wisconsin-Madison researchers have developed a new approach to manufacturing ingredients for pharmaceuticals by combining hydrogen with electricity. This process is more sustainable than traditional methods, which use large quantities of zinc metal, generating environmentally unfriendly waste.