Add BrightSurf on Google Email

University of Zurich


Global warming harms lakes

Research by the University of Zurich reveals that global warming is compromising successful lake clean-ups by reducing water turnover and promoting harmful algal blooms. The warmer temperatures are particularly affecting large lakes in Central Europe, where overfertilization has led to cyanobacteria growth.

SourceUniversity of Zurich·JournalNature Climate Change·DateJul 16, 2012

A small cut with a big impact

Researchers discovered how ARTD1's DNA recruitment is regulated during inflammation, influencing gene expression and inflammation. The protein is cleaved by caspase 7 into two pieces that can no longer bind to DNA, leading to more efficient gene expression.

SourceUniversity of Zurich·JournalMolecular Cell·DateMay 2, 2012

Chimpanzees have policemen, too

In a study published in PLOS ONE, researchers observed chimpanzee groups and found that high-ranking individuals intervene in conflicts to ensure group stability. This behavior is driven by a community concern interest, with more parties to a conflict resulting in greater policing.

SourceUniversity of Zurich·JournalPLOS ONE·DateMar 7, 2012

How chemotherapy becomes more effective

Cancer cells use an 'emergency brake' to protect themselves from chemotherapy drugs, which can be rendered inoperative by targeting a specific enzyme pathway. The study identifies PARP inhibition as a promising therapeutic approach to improve chemotherapy effectiveness.

SourceUniversity of Zurich·JournalNature Structural & Molecular Biology·DateMar 5, 2012

Tell me how you are -- and I know how long you will live

A 30-year study by University of Zurich researchers reveals a strong correlation between self-rated health and mortality risk, even after controlling for various factors. The study suggests that people with excellent health ratings have better chances of survival, indicating the importance of holistic approaches to healthcare.

SourceUniversity of Zurich·JournalPLOS ONE·DateFeb 9, 2012

Arm in plaster changes brain in 16 days

A new study by University of Zurich researchers found that brain areas responsible for the left hand adapt to compensate for an immobile right arm. The study suggests using the undamaged arm to strengthen the affected one through therapy, offering a potential treatment approach for stroke patients.

SourceUniversity of Zurich·JournalNeurology·DateJan 17, 2012

Oxidative DNA damage repair

The study reveals a DNA repair mechanism that can mitigate oxidative damage, which is linked to various diseases including cancer and Alzheimer's. This discovery holds promise for developing less invasive cancer therapies and early detection tests.

SourceUniversity of Zurich·JournalProceedings of the National Academy of Sciences·DateDec 27, 2011

Visualization of DNA synthesis in vivo

A new substance, F-ara-Edu, labels DNA with little to no impact on genome function, allowing for the visualization of DNA synthesis in vivo. This approach enables the identification of virus infection and cancerous growth sites due to abundant DNA replication in these tissues.

SourceUniversity of Zurich·JournalProceedings of the National Academy of Sciences·DateDec 13, 2011

Blossom end rot: Transport protein identified

A team of researchers has identified a protein that facilitates the radial transport of calcium ions from the root to the shoot, resolving a long-standing mystery. This breakthrough could lead to new strategies for preventing blossom end rot and other nutrient deficiencies in crops.

SourceUniversity of Zurich·JournalProceedings of the National Academy of Sciences·DateNov 23, 2011

Molecular corkscrew

Researchers have discovered that the protein p97/VCP aids DNA repair by unwinding proteins at damaged sites. This mechanism holds potential for improving radio- and chemotherapy effects on cancer cells.

SourceUniversity of Zurich·JournalNature Cell Biology·DateNov 8, 2011

Culture in humans and apes has the same evolutionary roots

A new study by researchers at the University of Zurich has found that humans and great apes share a common evolutionary origin for their cultural behaviors. The research, which analyzed data from over 100,000 hours of orangutan behavior, suggests that genetic factors and environmental influences play a significant role in shaping behav...

SourceUniversity of Zurich·JournalCurrent Biology·DateOct 20, 2011

How fair sanctions are orchestrated in the brain

A study published in Nature Neuroscience reveals that fair sanctions are orchestrated by the interaction between two frontal brain regions: the dorsolateral prefrontal cortex and the ventromedial prefrontal cortex. This communication is crucial for punishing norm violations at one's own expense.

SourceUniversity of Zurich·JournalNature Neuroscience·DateOct 6, 2011

Stomach bacterium damages human DNA

Research reveals that Helicobacter pylori causes DNA breaks in gastric mucosa cells, triggering genetic mutations and cell death. The study's findings suggest that prolonged infections can lead to exhaustion of the cell's repair response, exacerbating gastric carcinogenesis.

SourceUniversity of Zurich·JournalProceedings of the National Academy of Sciences·DateSep 5, 2011

Scavenger cells accomplices to viruses

Cell biologists from the University of Zurich have identified the infection mechanism for type-5 adenoviruses, revealing that viruses use scavenger cells to trigger an immune response and expose shielded receptors on lung epithelial cells. This discovery has implications for both gene therapy and cancer treatment.

SourceUniversity of Zurich·JournalNature Communications·DateJul 21, 2011

Similarities cause protein misfolding

Studies using single-molecule fluorescence reveal that neighboring protein domains with similar amino acid sequences are more prone to misfold, potentially leading to neurodegenerative diseases. This finding suggests that proteins have evolved to limit similarity between domains to prevent misfolding and maintain functionality.

SourceUniversity of Zurich·JournalNature·DateMay 31, 2011

The peculiar feeding mechanism of the first vertebrates

A team of researchers analyzed new conodont fossils and developed a 3D model of their feeding mechanism, revealing that these ancient vertebrates used teeth on upper lips and tongue to grasp food. The findings confirm the primitive nature of conodonts and suggest a common ancestor with lampreys.

SourceUniversity of Zurich·JournalProceedings of the National Academy of Sciences·DateMay 19, 2011

How TRIM5 fights HIV

Researchers have discovered TRIM5's mechanism of preventing HIV multiplication, which opens up new prospects for fighting the virus in humans. The protein triggers an immune response and stimulates the production of signal molecules to eliminate infected cells.

SourceUniversity of Zurich·JournalNature·DateApr 20, 2011

BSE pathogens can be transmitted by air

Researchers found that inhalation of prion-tainted aerosols induced disease with frightening efficiency in mice, infecting all within a single minute. This discovery challenges the widely held view that prions are not airborne and suggests precautionary measures for scientific labs, slaughterhouses, and animal feed plants.

SourceUniversity of Zurich·JournalPLOS Pathogens·DateJan 13, 2011