The new guidelines recommend a diet rich in carbohydrates or monounsaturated fats, with an emphasis on whole grains, fruits, vegetables, and low-fat milk. Increasing fiber intake from foods like grains, fruits, and vegetables is also recommended to improve diabetes control.
Researchers will study the effects of aging on the heart and evaluate an endurance exercise-training program's ability to improve diastolic function and serve as a therapy for congestive heart failure. The study aims to identify the precise dose of exercise necessary to restore normal diastolic function.
Researchers at UT Southwestern Medical Center have made significant progress in understanding the function of two proteins involved in neurotransmitter release. The study found that RIM1a is essential for long-term plasticity, a process critical for learning and memory. This breakthrough has broad implications for the development of dr...
Astronauts experience orthostatic intolerance after space flight, characterized by lightheadedness and dizziness. UT Southwestern researchers found that heart shrinking and becoming stiff is the primary cause, contrary to previous research suggesting a malfunction of the sympathetic nervous system.
Researchers at UT Southwestern Medical Center found that hyper-oxygen transmissible contact lenses reduce bacterial binding and promote tear exchange, leading to decreased bacterial growth. The study suggests these new lens materials will be a breakthrough in reducing the risk of eye infections.
Researchers at UT Southwestern Medical Center have developed a new procedure for delivering vaccines by manipulating dendritic cells in the skin, reducing production time from 10 days to just 24 hours. This breakthrough could lead to more effective cancer treatments and broader clinical applications.
Researchers have determined the three-dimensional structures of Eph and Ephrin proteins, which mediate bidirectional signaling between cells. This discovery holds promise for developing new cancer therapies by inhibiting or altering these protein interactions.
A study led by Suppes is investigating whether supplementing bipolar patients' medications with acupuncture can help reduce medication use. The research aims to explore the potential benefits of acupuncture in treating depressive symptoms associated with bipolar disorder.
Researchers found that two statins, atorvastatin and simvastatin, significantly reduced remnant lipoprotein (RLP) cholesterol levels, while pravastatin had no effect. This suggests that these drugs may have additional mechanisms for reducing cardiovascular risk beyond just lowering LDL cholesterol.
Dr. Scott Cameron, a renowned pediatric oncologist and molecular biologist, will lead research on cell growth and cancer at UT Southwestern Medical Center. The Children's Cancer Fund provided a $525,000 grant to support his four-year research program.
UT Southwestern researchers say automated external defibrillators (AEDs) can be used by anyone with minimal training, and are becoming increasingly widespread. Studies have shown that early defibrillation can dramatically improve survival rates for cardiac arrest victims.
UT Southwestern Medical Center has been awarded $3.6 million in funding to support 19 research projects across various disciplines. The largest grant will go towards developing a cancer-detecting blood test, which has already shown promising results in clinical trials.
Researchers found that abnormal alpha-interferon secretion in lupus patients leads to hyperactivation of dendritic cells, causing the immune system to attack healthy cells. This abnormal reaction can result in chronic inflammation affecting various organs, including the skin, kidneys, and joints.
Researchers at UT Southwestern discovered that traumatic brain injuries trigger a rapid and prolonged regeneration of neurons in mice, with long-term effects even in distant areas. This study suggests the potential to develop new treatments using adult stem cells to enhance injured brain capabilities.
A 42-month study published in Archives of Internal Medicine found that sustained-release sodium fluoride safely reduces the risk for vertebral fractures and increases spinal bone mass in older women with osteoporosis. The treatment combination also reduced bone resorption when adequate calcium and vitamin D were provided.
Researchers will study 12 astronaut crew members before, during and after space missions to assess cardiac mass, compliance and relaxation. Findings may help prevent cardiac atrophy and arrhythmias in individuals confined to long-term bed rest or with conditions associated with cardiac stiffness.
Researchers found that brain natriuretic peptide (BNP) levels are better at predicting adverse outcomes compared to traditional methods. Elevated BNP levels identified patients at high risk of dying or developing heart failure, even in those with no detectable heart damage.
A recent study by UT Southwestern Medical Center has identified a significant number of undiagnosed hypertension and diabetes cases in the Dallas County population. The project aims to reduce death and disability from coronary heart disease through analysis of collected data.
Neurons use Eph receptors and ephrin ligands to guide nerve fiber growth and form connections in the developing brain, a process called axon pathfinding. This research may ultimately lead to understanding how to coax nerves to regrow and regenerate.
UT Southwestern Medical Center has acquired a custom-crafted cryo-electron microscope to propel its cell-research capabilities. The new technology enables the analysis of sub-cell structures at sites in the cell where processes take place, providing valuable insights into cellular biology and disease mechanisms.
Researchers have found that combining amphetamines with speech therapy can significantly improve speech and language skills in patients with aphasia caused by stroke. The study suggests that the drug works by releasing noradrenaline, which may help brain cells wake up and become more responsive.
A clinical study found that children with severe hemophilia have a high risk of developing deep venous thrombosis linked to long-term catheter implants. Eight out of 15 boys in the study developed blood clots in the veins near their hearts.
Researchers found that patients with either a third heart sound or elevated jugular venous pressure were more likely to have progressive heart failure and subsequent hospital visits due to heart failure. The study highlights the importance of physical examinations in predicting outcomes for heart failure patients.
Mutations of the Lkb1 gene cause Peutz-Jeghers syndrome, a disorder characterized by polyps in the intestines and increased risk for cancerous tumors. Researchers found that Lkb1 regulates the formation of heart and blood vessels in embryos.
Young adults experiencing nontraumatic chest pains may have cocaine use, researchers say. Effective treatments include nitroglycerin or calcium blockers for constricted blood vessels.
The study identifies the carbohydrate response element-binding protein (ChREBP) as a key player in transforming excess glucose into fat. ChREBP binds to specific genes, activating enzymes that catalyze the transformation of excess glucose into fat, which can lead to weight gain.
Researchers at UT Southwestern Medical Center have identified a protein called myocardin, which is crucial for heart development in embryos. The study found that myocardin is necessary for the formation of cardiac genes and could potentially be used to convert non-cardiac cells into heart cells.
A study published in Neuron found that ephrin-B3 plays a key role in the connection between the brain and spinal cord, which is essential for forming motor connections. The research provides new insights into mirror movement disorder, a rare condition characterized by involuntary symmetrical movements of limbs.
A recent UT Southwestern Medical Center study found that substituting regular margarine for butter can lower LDL cholesterol levels by up to 11% in adults and 9% in children. The study also confirmed that a margarine-based diet is healthier than a butter-based diet, reducing heart-disease risk.
Researchers at UT Southwestern will advance genomic research on heart disorders to identify genes contributing to the condition and develop individualized drug therapies. The project will also provide free access to genome information and training for other scientists, complementing existing studies on heart disease prevention.
Researchers at UT Southwestern Medical Center found that automated external defibrillators (AEDs) can save the lives of sudden cardiac arrest victims aboard aircraft, with a survival rate of 40% in a two-year study. The smaller, automated device requires less training to use safely and is approved for airline use.
A study by Drs. Rebecca Sue Broyles and Jon Tyson found that comprehensive care reduced life-threatening illnesses and intensive care days by 48% and 42%, respectively. Comprehensive care also saved an average of $6,265 per infant compared to routine care.
Researchers at UT Southwestern Medical Center outline a method for securely collecting sensitive medical research data via the Internet. This approach enables faster and cheaper data collection with the same level of security as traditional methods.
The NIH-funded program will bring together researchers from the Center for Biomedical Inventions and the Touchstone Diabetes Center to develop novel therapies for type II diabetes. Researchers aim to translate basic science into medical therapy, exploring new approaches in treatment and delivery methods.
Researchers at UT Southwestern Medical Center found a strong link between brain cell loss in Gulf War veterans and abnormal over-production of dopamine, a neurotransmitter chemical important in degenerative brain diseases. The study suggests that the brain damage may be having a real effect on these veterans' brain function.
Researchers at UT Southwestern Medical Center discovered a new protein, SMAC, which promotes apoptosis and is responsible for cell death. The study found that only seven amino acids are necessary to induce cell death, making it possible to design drugs based on these amino acids.
A $10 million-per-year project allows researchers worldwide to collaborate on studying cell signaling, with the goal of developing a 'virtual cell' for testing new drugs. The Alliance for Cellular Signaling (AFCS) will help understand the global properties of cellular signaling, leading to breakthroughs in medical research.
UT Southwestern researchers identified a specific protein in sensory nerves that contribute to cyclosporine-induced hypertension. The study found that mice lacking this protein experienced no increase in blood pressure when administered cyclosporine.
A UT Southwestern study shows that vitamin E can help reduce inflammation caused by white blood cells, which is a significant factor in diabetic vascular disease. The study found that increasing vitamin E intake reduced monocyte activity and promoted less inflammation and free radicals in type II diabetics.
A study published in Radiology found that Gulf War veterans experienced significant brain-cell loss, particularly in the brain stem, right basal ganglia, and left basal ganglia. The loss of functioning brain cells was linked to various symptoms, including joint pain, fatigue, dizziness, and mental confusion.
Researchers at UT Southwestern Medical Center have developed an easy and inexpensive index to measure the severity of Alzheimer's disease. The index correlates a simple lab test determining platelet Alzheimer's plaque protein (APP) in blood with cognitive decline, as measured by the Mini-Mental State Exam.
A national study found that 85% of chronically depressed patients improved after three months of treatment combining antidepressant Serzone with Cognitive Behavioral Analysis System of Psychotherapy (CBASP). The combination therapy was more effective than either medication or psychotherapy alone for treating chronic depression.
A study published in The New England Journal of Medicine found that a high-fiber diet can lower blood glucose levels and decrease insulin levels in patients with type II diabetes. Patients who consumed 50 grams of fiber per day showed a 10% reduction in glucose levels, compared to the recommended 24 grams of fiber per day.
A recent UT Southwestern Medical Center study found that 20% of women with lower urinary-tract symptoms, including incontinence, had undiagnosed bladder obstructions. The researchers used urodynamics testing to identify the subset of women who would benefit from more specialized treatment.
A new study will investigate whether cognitive therapy can prevent relapses and recurrences of major depression as effectively as standard antidepressant medication. The study, funded by a $1.6 million NIMH grant, aims to help patients who suffer from recurring episodes of major depression.
Researchers at UT Southwestern Medical Center have found evidence of brain-stem damage in Gulf War veterans who experience dizziness, suggesting that the symptoms are caused by chemical and nerve agent exposure. The study also highlights a higher risk of death in motor vehicle accidents among these veterans.
A study published in the Journal of Applied Physiology reveals that a specific pathway controls the breakdown of proteins regulating muscle type. The ubiquitin/proteasome pathway determines which proteins are degraded, allowing for the switching of muscle type during exercise training or constant contraction.
A study of genetically obese rats revealed that an overabundance of fat can collect in heart cells and cause them to die, leading to heart failure. The researchers found that a diabetes drug prevents this damage by oxidizing the fat so it burns up rather than accumulating and causing heart-cell death.
Researchers at UT Southwestern Medical Center found that higher PSA levels are associated with faster prostate growth, allowing doctors to predict and potentially slow growth through treatment. This study provides critical information for planning a treatment, emphasizing the importance of annual PSA tests for men over age 50.
Researchers at UT Southwestern Medical Center found that protein gelsolin plays a crucial role in disassembling the inner skeleton of cells, which can lead to cancer development. By understanding how gelsolin works, scientists hope to develop new cancer-fighting drugs by stimulating or blocking its activation.