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Washington University in St. Louis


A protein key to the next green revolution sits for its portrait

A team at Washington University in St. Louis solved the structure of NolR, a master off-switch for the nodulation process that converts bacteria into nitrogen-fixing organisms. The discovery provides insight into the biological machinery of nitrogen-fixing and may lead to re-engineering crop plants with on-site nitrogen-fixing systems.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·DateApr 29, 2014

Scientists find a molecular clue to the complex mystery of auxin signaling in plants

Researchers at Washington University in St. Louis have identified a key protein in the auxin signaling network that may help understand the entire mechanism. The protein's interaction domain allows it to form chains with other proteins, fine-tuning the response of individual cells to auxin and producing detailed patterns on plant leaves.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·DateMar 24, 2014

Microbes buy low and sell high

A team of researchers found that microbes engage in market-like behaviors, including comparing bids for commodities, hoarding resources, and eliminating competitors. This discovery has implications for understanding microbial interactions and could lead to new approaches in social microbiology.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·DateJan 13, 2014

Odor receptors discovered in lungs

Scientists have found odor receptors in lung tissue that can detect cigarette smoke and other irritants, triggering a response to constrict airways. These receptors, called pulmonary neuroendocrine cells, may be responsible for the chemical hypersensitivity characteristic of respiratory diseases such as COPD.

SourceWashington University in St. Louis·JournalAmerican Journal of Respiratory Cell and Molecular Biology·DateJan 2, 2014

Staying ahead of Huntington's disease

Researchers have discovered that naturally occurring gatekeeper sequences on either side of a key protein mutation in Huntington's disease can prevent the formation of toxic structures. This breakthrough offers new hope for understanding and treating the devastating neurodegenerative disorder.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·DateDec 11, 2013

VIP treatment for jet lag

A study at Washington University in St. Louis found that a small molecule called VIP can temporarily desynchronize brain cells, but also enables them to re-synchronize more quickly to abrupt shifts in daily light-dark schedules. This effect may be useful for travelers and shift workers who struggle with jet lag.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·DateOct 28, 2013

Ignorance is sometimes bliss

Researchers discovered that a lack of information about kinship can lead to increased cooperation and reduced conflict within groups. This phenomenon, known as the veil of ignorance, is observed in both social insects and genes, suggesting its evolutionary advantages.

SourceWashington University in St. Louis·JournalBiology Letters·DateOct 23, 2013

Model organism gone wild

Scientists studying the wild strain of the model organism Dictyostelium discoideum discovered that some clones can farm bacteria and carry defensive symbionts to protect their crops. The researchers isolated wild clones from soil and found that these clones were more complex than previously thought.

SourceWashington University in St. Louis·JournalNature Communications·DateSep 13, 2013

Brain's flexible hub network helps humans adapt

Research from Washington University in St. Louis suggests a 'flexible hub' theory of brain function, where the fronto-parietal network coordinates processing among specialized networks for novel cognitive tasks. This allows for rapid learning and adaptation, enabling humans to switch between different skills learned in different contexts.

SourceWashington University in St. Louis·JournalNature Neuroscience·DateAug 12, 2013

Social amoebae travel with a posse

Scientists have discovered that social amoebae can cultivate two bacterial strains, one edible and the other toxic, which differ by only one key mutation. This mutation altered the expression of genes in the non-food strain, making it edible, while the food strain retained its defense mechanisms.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·DateJul 29, 2013

How rice twice became a crop and twice became a weed -- and what it means for the future

Evolutionary biologist Kenneth Olsen has examined the genetics of hull color in rice, finding that different mutations underlie the emergence of traits in both cultivated and weedy forms. The findings suggest that crops reverted to wild forms by reversing genetic changes, but with a more complex history than initially thought.

SourceWashington University in St. Louis·JournalJournal of Evolutionary Biology·DateJul 17, 2013

Older adult clumsiness linked to brain changes

New research from Washington University in St. Louis suggests that older adults use less effective reference frames to visualize nearby objects, leading to difficulties with daily tasks like dialing phones and grasping objects. This study sheds light on the cognitive changes associated with aging and their impact on hand-eye coordination.

SourceWashington University in St. Louis·JournalPsychological Science·DateJun 4, 2013

Grains of sand from ancient supernova found in meteorites

Researchers found two tiny silica grains in primitive meteorites, with unusual isotopic signatures suggesting they originated from a single core-collapse supernova. This discovery provides clues to the complex nuclear and convective processes operating within stars, shedding new light on stellar evolution and the solar system's formation.

SourceWashington University in St. Louis·JournalThe Astrophysical Journal Letters·DateApr 19, 2013

Wang's technology may answer host of medical questions

Researchers have developed a new technology called photoacoustic flowoxigraphy that allows for the measurement of oxygen in individual red blood cells in real-time. This breakthrough could lead to a better understanding of oxygen delivery to normal and diseased tissues, as well as how different disease therapies impact oxygen levels.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·DateMar 25, 2013

When it rains these days, does it pour?

Researchers analyzed over 70 years of hourly precipitation data from 13 US sites to test the hypothesis that storms are becoming more frequent and intense as the climate warms. They found a significant steady increase in stormy activity on the Olympic Peninsula in Washington State, which is famously prone to drizzle.

SourceWashington University in St. Louis·JournalNature Climate Change·DateMar 17, 2013