Articles tagged with Cancer Treatments
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A study published in The Journal of Nuclear Medicine found that imaging progesterone receptor (PR) status can identify responders and nonresponders to endocrine therapy in early stages. PR imaging with F-18-FFNP PET may help distinguish between patients who will benefit from hormone-based therapies.
Rheumatoid arthritis patients face significant challenges including disability, life expectancy drops, heart attack risk, and joint destruction. Mayo Clinic researchers offer guidance on diagnosis, treatment, and management to improve outcomes for patients.
A study published in Cancer Research found that increasing coffee consumption is inversely associated with the risk of developing basal cell carcinoma, the most common form of skin cancer. The study's results suggest that caffeine may be responsible for this decreased risk.
Researchers found that inhibiting a key immune response early on can shorten TB treatment time and prevent relapse. In a study, mice treated with standard TB medication plus a TNF-alpha inhibitor had a significantly lower bacterial burden than those receiving only the standard treatment.
A new study found that the federal government made $13 billion in duplicative payments to provide health-care services to veterans enrolled in Medicare Advantage plans. The researchers analyzed over 1 million veteran records and found that 61% used both VA and Medicare Advantage coverage.
A new animal study finds that oxytocin helps regulate food intake and energy metabolism without causing adverse effects. Oxytocin administered through daily injections or implanted mini pumps reduced food consumption, body weight, and liver fat, improving glucose tolerance and reducing abdominal fat.
Scientists have identified genetic heart conditions as a possible cause of unexplained stillbirths, with up to 8% of cases attributed to cardiac channelopathies. The research, led by Ms Alice Ghidoni, used molecular screening to detect disease-causing variants in stillborn fetuses.
A study in Nature Medicine reveals that boosting a protein pathway in the body's blood-making system can protect against radiation poisoning. The researchers found that pharmacologic enhancement of the Thbd-aPC pathway can accelerate recovery of hematopoietic progenitor cell activity and reduce harmful effects in mice.
The American Association for Thoracic Surgery task force recommends expanded lung cancer screening guidelines using low-dose computed tomography (LDCT) for high-risk individuals. The new guidelines increase the recommended age range to 79 and expand eligibility to smokers and former smokers with specific risk factors.
A molecule believed to suppress tumor growth is found to accelerate anaplastic thyroid cancer cell growth when active. Researchers discovered a potential therapeutic target by identifying a gene promoting growth in cancer cells.
A study by Steffen Torp and colleagues found that long-term cancer survivors take significantly more sick leave than their non-cancer counterparts. Socio-demographic factors, such as education level and family status, were key predictors of sick leave, rather than the type or severity of cancer.
The number of Americans with a history of cancer is expected to reach 18 million by 2022, with 45% of survivors aged 70 or older. Improved cancer survival rates have led to the growth in survivor prevalence despite decreasing cancer incidence rates.
Researchers at Johns Hopkins University have developed a lab-on-chip platform that can sort microscopic particles and bits of biological matter using gravity or simple forces. The device, similar to speed bumps on a road, separates particles based on weight, size or other factors, holding promise for early cancer detection.
Researchers identified a molecular marker that quickly distinguishes between fast- and slow-progressing forms of chronic leukemia. The finding enables patients with aggressive disease to start treatment sooner.
A joint research project between Aarhus University and the Danish Cancer Society shows that mindfulness-based psychological therapy helps reduce anxiety and depression in cancer patients. Mindfulness teaches patients to be more conscious of life as it happens, reducing negative thoughts and worries.
Researchers found African-American survivors have unmet needs in dealing with fears of recurrence, while spouses report concerns about stress and anxiety. The study highlights the importance of culturally appropriate interventions, including improved communication and symptom management for better outcomes.
Researchers have identified new therapeutic targets for cancer treatment by studying the interaction between natural killer cells and tumor cells. A study found that targeting JAK1 and JAK2 kinases may aid in eradicating tumors resistant to NK cell killing. Additionally, another study revealed that periostin plays a crucial role in chr...
A new analysis found that many adolescent and young adult cancer survivors experience chronic medical conditions, poor quality of life, and barriers to healthcare access. The study suggests that these negative behaviors are potentially modifiable through proper follow-up care and promotion of healthy habits.
Researchers at UT Southwestern Medical Center have mapped the atomic-level architecture of the CLOCK complex, a key component of the body's circadian rhythm. The study provides insights into how this protein works and may lead to better treatments for insomnia, diabetes, and cancer.
A Mayo Clinic-led study found that high doses of American ginseng reduced cancer-related fatigue in patients more effectively than a placebo. The herb showed significant improvement in general exhaustion at eight weeks, with no apparent side effects.
Fox Chase researchers found that patients' socioeconomic status influences their treatment choices, with those having higher incomes opting for more effective but expensive treatments. This study highlights the need for policymakers to consider cost sensitivity in cancer care.
Researchers at the University of New South Wales have discovered a potential new way to regulate the immune response, increasing good regulating cells to treat autoimmune diseases. The treatment involves injecting cell-signalling proteins called cytokines, which boost the body's immune system without causing overdrive.
A randomized controlled trial found that using mobile technology, remote coaching, and financial incentives improved patients' diet and activity levels. The study's interventions leveraged handheld technology to make self-monitoring more convenient and extend decision support into life contexts.
Researchers at Ohio State University Comprehensive Cancer Center discovered a small inherited change in DNA responsible for overactivating the BAALC gene, which is associated with poor treatment response in acute leukemia. The study found that high levels of RUNX1 protein are linked to high BAALC gene expression.
Researchers developed a new method to identify vaccine targets for Streptococcus pneumoniae, the most common cause of bacterial meningitis. Gene therapy has shown promise in treating adenosine deaminase deficiency by correcting B cell tolerance problems and supporting treatment options for patients with severe combined immunodeficiency.
Researchers developed a stapled BIM BH3 peptide that competitively binds to anti-apoptotic proteins, leading to enhanced apoptosis in cancer cells. The compound suppresses tumor growth in mice and works synergistically with other pharmaceutical agents.
Mayo Clinic researchers present studies on adjuvant hormonal therapy for prostate cancer patients, finding no negative impact on overall survival. They also release results of a study on safe intervals for PSA screening in young men.
Research in Psychological Science explores public reaction to task force recommendations, citing factors such as anecdotes and perception of medical treatments. The study suggests that changing the public's view on prostate-cancer screenings may require pictorial displays to help evaluate data more effectively.
Researchers compared chest tube drainage and talc slurry for pleurodesis to indwelling pleural catheters in treating lung effusions. The study found no significant difference in dyspnea between the two treatments, but IPCs reduced hospital time despite increasing adverse events.
The American Gastroenterological Association will showcase innovative data and advancements in treating gastrointestinal (GI) disorders during the Digestive Disease Week 2012. The presentation of exciting, cutting-edge information will help physicians diagnose and treat GI disorders more effectively.
A nurse practitioner-driven consultation improved cancer patients' emotional health and quality of life, with a significant improvement in those who received the intervention. The study suggests that incorporating palliative care discussions into oncology practices can lead to better patient outcomes.
Researchers investigated whether preoperative imaging differed between black and white women with breast cancer. They found no disparity in the use of imaging, contrary to some earlier studies. However, they did note that women from more educated areas were more likely to receive certain types of imaging.
A meta-analysis confirms statins reduce major vascular events by 21% in those with low risk of vascular disease. Statin therapy outweighs known side effects, suggesting current guidelines may need revision.
A recent study from Fox Chase Cancer Center found that nearly half of the research presented at ASCO's annual meeting came from researchers with industry ties. The study suggests a growing dependence on industry funding for cancer research, highlighting the need to investigate potential conflicts of interest.
A new study found that safer partial nephrectomy surgery is less common among older, sicker, and poorer patients who rely on Medicare or Medicaid for care. This disparity may be due to limited access to care or lower proficiency in performing the advanced surgical technique.
A new study by Henry Ford Hospital urologists finds that robot-assisted partial nephrectomy (RAPD) offers fewer complications than laparoscopic partial nephrectomy (LPN), but notes limitations due to data availability on surgical expertise and cancer complexity. The procedure has become the standard treatment for kidney cancer, with co...
Researchers at Ohio State University Comprehensive Cancer Center identified microRNA-3151 as a new independent prognostic marker in certain patients with acute leukemia. The study found that overexpression of miR-3151 leads to poor treatment responses and shorter survival periods, independent of other gene mutations.
Researchers at CNIO successfully test first gene therapy to combat aging, extending mouse lifespan up to 24 percent and improving health. The therapy delivers a 'rejuvenating' effect using telomerase enzyme, repairing or delaying DNA damage.
Researchers at Rutgers University have discovered a new way to stimulate the activity of immune cell opiate receptors, leading to efficient tumor cell clearance. The study builds upon previous research showing that replenishing endorphins can prevent stress and immune problems in fetal alcohol-exposed test subjects.
A UNC-led team discovers that lung cancer molecular subtypes correlate with distinct genetic alterations and patient response to therapy. The study refines their previous report on three molecular subtypes of non-small cell lung cancer, suggesting new avenues for targeted treatment.
Scientists at NC State University developed a method to turn gene expression on and off using light-activated molecules. This technique enables precise control over gene function, potentially leading to targeted therapies for diseases like cancer.
A recent study published in the Journal of the National Cancer Institute found that physical activity is associated with reduced mortality in breast and colon cancer patients. The research suggests that exercise may provide benefits such as improved insulin levels, reduced inflammation, and enhanced immunity for cancer survivors.
Heidelberg University Hospital's Breast Center reports excellent treatment results for breast cancer patients in Germany. Eighty-six percent of patients survived the first five years after onset of treatment and 80% remained disease-free during this period.
Researchers identified a genetic pathway that influences the spread of cancer cells, which could lead to new treatment avenues. The study found that changes in genetics affect DNA methylation, causing cells to divide uncontrollably.
A new study finds that differences in screening account for 42% of the observed disparity in colorectal cancer incidence and 19% of disparity in mortality between blacks and whites. Equal access to care could substantially reduce racial disparities in colorectal cancer rates.
Researchers at Joslin Diabetes Center have identified a critical mechanism involving the TOR protein kinase and master gene regulator proteins SKN-1 and DAF-16, which can increase stress resistance and longevity in various species.
Researchers at St. Jude Children's Research Hospital found no significant difference in survival rates between African-American and white children treated for virtually all cancers during a 15-year period. The study suggests equal access to comprehensive treatment translates into equally good outcomes, closing the racial survival gap.
Researchers at Moffitt Cancer Center found that adolescents newly diagnosed with cancer have strong concerns about their ability to have children as cancer survivors. Parents often inaccurately relayed their child's reproductive concerns and underestimated their daughters' desires for future parenthood.
Researchers have found that adding boron-nitride nanotubes to cancer cells can increase the effectiveness of a minimally invasive treatment for soft tissue tumors. The treatment, known as Irreversible Electroporation, has been shown to kill twice as many cancer cells when BNNTs are present on the cell surface.
Girls who start puberty prematurely are at risk of psychological problems, including adolescent behavior issues, and may face increased risks of sexual abuse and early pregnancy. Treatment options, such as hormone therapy, can help manage symptoms and improve outcomes.
A study confirms that prostate cancer screening is widely ignored in men aged 75 or older, defying 2008 guidelines. Nearly half of men in this age group continue to receive screenings, highlighting the need for selective screening.
A Canadian study found opioids significantly improved the quality of life and relief from shortness of breath for advanced COPD patients. However, physicians were hesitant due to lack of guidance, fear of respiratory suppression, and concerns about censure. Innovative educational initiatives may help bridge this gap in care.
Researchers at Bascom Palmer Eye Institute have developed a novel gene therapy to treat Leber Hereditary Optic Neuropathy (LHON), an inherited genetic defect that causes rapid vision loss. The treatment successfully replaces mutated genes with healthy ones, restoring visual function in experimental models.
A team led by Martin Friedlander at Scripps Research Institute has received a $10.2 million grant to develop a new treatment strategy for diabetic retinopathy, macular degeneration, and other vision disorders. The approach targets a strand of micro-RNA that promotes abnormal blood vessel growth.
Researchers found that early treatment can significantly improve outcomes for a rare and often undiagnosed form of encephalitis. The study analyzed 565 cases of Anti-NMDA Receptor Encephalitis and determined that second-line therapy improves outcomes compared to repeating treatments or no additional treatments.
Three large studies from India, China, and the Middle East expose a consistent pattern of inadequate treatment for women with acute coronary syndrome (ACS), resulting in poorer outcomes. Women tend to be admitted later, have more comorbid disease, and receive less aggressive treatment than men.
A Scripps Research Institute scientist has been awarded a $1 million grant to develop new tests for stress-associated diseases, including atherosclerosis, Alzheimer's disease, and Parkinson's disease. The goal is to identify drug leads that can prevent oxidative damage in zebrafish.
A study published in Archives of Otolaryngology – Head & Neck Surgery suggests that targeted swallowing exercises can alleviate debilitating side effects in people undergoing chemoradiation therapy for head and neck cancer. Patients who performed five targeted swallowing exercises throughout their CRT showed significantly better scores...
A study found the diagnostic yield of colonoscopy for melena after a nondiagnostic upper endoscopy to be 4.8 percent, significantly lower than previously reported. The rate of therapeutic intervention was also very low at 1.7 percent, suggesting that most procedures are diagnostic-only and can be performed on an elective basis.
The Prospective Surveillance Model is a novel approach to managing pathological conditions resulting from cancer treatment by promoting early identification and treatment of known side effects. The goal of the model is to identify impairment at the earliest onset, alleviate impairment, or prevent it from progressing.