Articles tagged with Cancer Treatments
A set of evidence-based clinical practice guidelines has been established to guide the diagnosis and treatment of low-back pain in the US. The guidelines recommend careful observation, over-the-counter pain medication, and targeted physical activity for most patients, while reserving imaging and surgery for specific cases with red flags.
A new study found that phone therapy is just as effective as in-person therapy for people with mild to moderate depression and anxiety. The research from the University of Cambridge also showed that providing talking therapies over the phone can save the NHS money, with a cost per session 36.2% lower.
Researchers at Karolinska Institutet have made a major breakthrough in type II diabetes treatment by inhibiting VEGF-B. The study shows that VEGF-B inhibition can prevent and treat insulin resistance, which is related to the storage of fat in muscles, blood vessels, and heart.
A nationwide study found that primary-care physicians earn an average of $2.8 million less than their specialist colleagues over a lifetime, potentially discouraging medical students from pursuing primary care. The study's authors recommend reducing pay disparities to ensure adequate access to primary care.
A Baylor University researcher has developed a model likening grief stages to a pinball machine, explaining why grieving is never complete and can be triggered by various events. The study uses the pinball analogy to help individuals in mourning understand their chaotic experience and prepare for future triggers.
A new study reveals that young cancer survivors frequently forego routine medical care because of financial constraints. Despite having health insurance, they face significant cost burdens, which can lead to unmet health needs.
A University of Colorado study shows that bladder cancer patients with high CD24 expression have worse prognoses and may benefit from anti-androgen therapies. CD24 expression depends on androgens, and blocking these hormones may diminish the proliferative and metastatic power of bladder cancer cells.
A new research model estimates that men with low-risk prostate cancer who choose active surveillance may live 6.4 years without treatment, while those who undergo immediate radical prostatectomy may gain an average of 1.8 months of additional life.
Researchers found that high viral load and cancer-specific viral gene expression are key markers for identifying HPV-driven tumors. These findings suggest that HPV DNA positivity alone is a poor predictor of outcome in head and neck cancers.
A new study by the University of Michigan Health System and VA Ann Arbor Healthcare System found a significant link between substance-use disorders and mortality in veterans with PTSD. Younger veterans, including those from Iraq and Afghanistan conflicts, showed a stronger association between substance-use disorders and death.
A significant reduction in the risk of developing diabetes was observed in individuals who underwent bariatric surgery compared to those receiving traditional care. The Swedish Obese Subjects study found that bariatric surgery can reduce the risk of diabetes by over 80% among obese patients.
Researchers found a single HPV protein necessary for cervical cancer and pre-cancer growths to survive. A gene-silencing technique may cripple the protein and eliminate cervical cancer and pre-cancerous growths in mice, offering a potential new treatment option.
Scientists at Uppsala University have successfully cloned a T-cell receptor that binds to an antigen associated with both prostate and breast cancers. This breakthrough enables genetically modified T cells to specifically kill these cancer cells, offering hope for new treatment possibilities.
Chemists at UMass Amherst have developed a sensor array system using gold nanoparticles and proteins that can rapidly detect and identify different cancer types in living tissue. The technology uses a 'nose' strategy similar to how humans recognize odors, allowing for precise detection of metastatic cells with high accuracy.
Researchers at UGA have made a major medical breakthrough by discovering how an oxygen-sensing bacterial protein senses oxygen through reversible structural changes in an iron-sulfur cluster. This mechanism could ultimately lead to a better understanding of the aging process and new treatments for human diseases.
A study published in American Journal of Pathology found that two genetic mutations, beta-catenin and insulin-like growth factor 2 (IGF-2), cooperate to induce adrenal cancer. The research provides new insights into the rare and deadly disease, which affects about 600 Americans annually, and may lead to targeted therapies.
The AAO-HNSF 2012 new poster presentations cover various topics in otolaryngology, including rhinoplasty, facial trauma, and head and neck cancer. The studies aim to improve treatment outcomes and address common challenges in the field.
A review article highlights the role of interleukin-18 (IL-18) in inflammation and its potential as a therapeutic target for pulmonary inflammatory diseases. Therapies blocking IL-18 activity may offer effective treatment options for conditions like bronchial asthma and COPD.
Researchers found that a medication inhibiting inflammation showed promise in treating major depression, especially in individuals with high levels of inflammation. The study employed infliximab, an antibody blocking tumor necrosis factor, and demonstrated improved symptoms in subjects with elevated C-reactive protein levels.
Researchers at Cleveland Clinic's Lerner Research Institute and Anesthesiology Institute have discovered a potential new treatment for Alzheimer's disease. The compound MDA7 has been shown to induce beneficial immune responses that limit the development of the disease, restoring cognition, memory, and synaptic plasticity in animal models.
A specific genetic variation found in people who carry a 'G' instead of an 'A' at a particular spot in their genetic code is associated with a six-fold higher risk of developing certain types of brain tumors. Researchers hope this discovery will lead to better surveillance and diagnosis.
A new study published in The Journal of Urology reports that PSA testing has led to improved survival rates for patients with newly diagnosed prostate cancer that has spread to the bones or other parts of the body. The disparity between African American and Caucasian men has been resolved, with African American men now having a compara...
A study published in European Journal of Epidemiology found that cancer survival rates in Germany have aligned significantly since reunification. While there are still slight differences, they have decreased compared to the pre-reunification era.
Researchers at the University of Strathclyde have developed a new approach to delivering green tea extract, epigallocatechin gallate, directly to tumors. In initial laboratory tests, nearly two-thirds of treated tumors shrank or disappeared within one month with no side effects to normal tissues.
Investigators found that low oxygen levels increase SMN2 exon 7 skipping, reducing survival motor neuron protein levels. Higher oxygen treatment improved motor function and reduced disease severity in a mouse model of severe SMA.
Researchers have successfully integrated RNA switches into viral genetic material to control gene expression, increasing the production of therapeutic genes by ten times. This technology has vast potential for various research and medical applications.
A retrospective study published in Archives of Dermatology found that patients with psoriasis treated with tumor necrosis factor (TNF) inhibitors have a significantly lower risk of heart attack compared to those not treated with TNF inhibitors. The study included 8,845 patients and adjusted for other MI risk factors.
The FastStitch device, developed by Johns Hopkins undergraduates, features a cross between a pliers and a hole-puncher to guide stitch placement and prevent accidental punctures. The device has already received recognition and funding to move forward, aiming to simplify and improve the closure process for surgeons.
Researchers found that B cells from patients with chronic GVHD are more active and resistant to programmed cell death. The study identifies BAFF as a promising target for developing new therapies, such as anti-BAFF agents or small molecule inhibitors.
The University of Delaware is part of a $2.5 million NIH-funded project to create artificial salivary glands. Researchers hope to develop new solutions for Xerostomia, a side effect of radiation treatment for head and neck cancers. The project involves developing hydrogels that can guide salivary cells to form functional glands.
Scientists have discovered that high iron levels can cause bowel cancer in people with a faulty gene, increasing the risk by two to three times. A diet low in iron prevents bowel cancer from developing altogether.
Researchers identified a previously unknown subtype of Ewing sarcoma with genetic factors related to long-term survival. A specific gene change between primary and metastatic stages may lead to better treatment.
Research finds that TRPM7 protein plays a critical role in breast cancer cell metastasis. High levels of TRPM7 expression are associated with poor patient outcomes and increased risk of distant metastases. The study suggests that targeting this protein could block metastasis, offering new therapeutic opportunities.
Researchers found tristetraprolin (TTP/ZFP36) to be a tumor suppressor that impairs lymphoma development and maintenance. The study's findings suggest TTP could be a key target for treating cancers with MYC involvement, including relapsed and refractory tumors.
A recent study in Pakistan found limited awareness of breast cancer among most women, with many unaware of self-breast exams and clinical breast exams. However, willingness to address health issues was high, and the majority of general practitioners understood major risk factors and importance of early detection.
Researchers found that herbal agents can prevent sunburn and limit UV damage, with golden serpent fern and Asian ginseng showing promising photoprotective properties when taken orally. Green tea applied topically also offers photoprotection in sufficient doses.
Researchers at Ohio State University found that liver cancer cells lose the ability to produce glucose due to microRNA-23a overexpression. Suppressing miR-23a might reverse this process and offer a new treatment for hepatocellular carcinoma, the most common form of liver cancer.
Two men with longstanding HIV infections have no detectable traces of HIV after bone marrow transplants, suggesting protection under anti-retroviral therapy. Researchers plan to study additional HIV-positive patients and explore tracing HIV in tissues.
Researchers from the British Columbia Cancer Research Center analyzed lung tumors exposed to arsenic, highlighting genetic and epigenetic changes driving carcinogenesis. These findings may help prevent arsenic-related cancer in regions with low exposure levels.
A meta-analysis of 10 studies found that cognitive behavioral therapy and pharmacologic interventions decrease depressive symptoms in cancer patients. The study also identified effective interventions for different stages of cancer and cultural subpopulations.
Directly targeting microRNA-125b to block androgen receptor activity represents a novel approach for treating castrate-resistant prostate cancer. The study provides new insight into the mechanism of miR-125b regulation of castrate-resistance prostate cancer.
The AACR-Kure It Grant will support innovative kidney cancer research, aiming to improve patient survival and quality of life. The grant recipient will receive $250,000 over two years and recognition at the AACR Annual Meeting.
Researchers at Stanford University have created a collection of compounds called bryologs that can activate latent HIV reservoirs with equal or greater potency than the original substance. The discovery holds promise as a practical way to flush out dormant viruses, offering hope for a cure for AIDS patients.
Researchers at Dana-Farber Cancer Institute have identified a new type of energy-burning fat cell, called 'beige fat,' which may have therapeutic potential for treating obesity and diabetes. Beige fat cells can burn off calories rather than store them, unlike 'white fat' cells.
A national survey of physicians found that patient fears and misinformation are major barriers to treating menopausal symptoms. The Endocrine Society has developed the Menopause Map, an online tool to guide women through treatment options and assess individual risk factors.
Researchers at HZDR demonstrate proton acceleration in the direction of the laser light, achieving unprecedented high energies. This breakthrough enables future cancer therapy applications with ultra-short pulse lasers.
A study published in The Journal of Nuclear Medicine found that imaging progesterone receptor (PR) status can identify responders and nonresponders to endocrine therapy in early stages. PR imaging with F-18-FFNP PET may help distinguish between patients who will benefit from hormone-based therapies.
Rheumatoid arthritis patients face significant challenges including disability, life expectancy drops, heart attack risk, and joint destruction. Mayo Clinic researchers offer guidance on diagnosis, treatment, and management to improve outcomes for patients.
A study published in Cancer Research found that increasing coffee consumption is inversely associated with the risk of developing basal cell carcinoma, the most common form of skin cancer. The study's results suggest that caffeine may be responsible for this decreased risk.
Researchers found that inhibiting a key immune response early on can shorten TB treatment time and prevent relapse. In a study, mice treated with standard TB medication plus a TNF-alpha inhibitor had a significantly lower bacterial burden than those receiving only the standard treatment.
A new study found that the federal government made $13 billion in duplicative payments to provide health-care services to veterans enrolled in Medicare Advantage plans. The researchers analyzed over 1 million veteran records and found that 61% used both VA and Medicare Advantage coverage.
A new animal study finds that oxytocin helps regulate food intake and energy metabolism without causing adverse effects. Oxytocin administered through daily injections or implanted mini pumps reduced food consumption, body weight, and liver fat, improving glucose tolerance and reducing abdominal fat.
Scientists have identified genetic heart conditions as a possible cause of unexplained stillbirths, with up to 8% of cases attributed to cardiac channelopathies. The research, led by Ms Alice Ghidoni, used molecular screening to detect disease-causing variants in stillborn fetuses.
A study in Nature Medicine reveals that boosting a protein pathway in the body's blood-making system can protect against radiation poisoning. The researchers found that pharmacologic enhancement of the Thbd-aPC pathway can accelerate recovery of hematopoietic progenitor cell activity and reduce harmful effects in mice.
The American Association for Thoracic Surgery task force recommends expanded lung cancer screening guidelines using low-dose computed tomography (LDCT) for high-risk individuals. The new guidelines increase the recommended age range to 79 and expand eligibility to smokers and former smokers with specific risk factors.
A molecule believed to suppress tumor growth is found to accelerate anaplastic thyroid cancer cell growth when active. Researchers discovered a potential therapeutic target by identifying a gene promoting growth in cancer cells.
A study by Steffen Torp and colleagues found that long-term cancer survivors take significantly more sick leave than their non-cancer counterparts. Socio-demographic factors, such as education level and family status, were key predictors of sick leave, rather than the type or severity of cancer.
The number of Americans with a history of cancer is expected to reach 18 million by 2022, with 45% of survivors aged 70 or older. Improved cancer survival rates have led to the growth in survivor prevalence despite decreasing cancer incidence rates.
Researchers at Johns Hopkins University have developed a lab-on-chip platform that can sort microscopic particles and bits of biological matter using gravity or simple forces. The device, similar to speed bumps on a road, separates particles based on weight, size or other factors, holding promise for early cancer detection.
Researchers identified a molecular marker that quickly distinguishes between fast- and slow-progressing forms of chronic leukemia. The finding enables patients with aggressive disease to start treatment sooner.