Articles tagged with Cancer Treatments
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Treating chronic hepatitis C with antiviral drugs could reduce liver cancer risk by half, according to a meta-analysis of published research. In some cases, treatment can even prevent the development of hepatocellular carcinoma, the most common form of liver cancer worldwide.
A randomized trial of over 14,000 male physicians found that long-term daily multivitamin use resulted in a modest but statistically significant reduction in cancer incidence. The study suggests that multivitamins may have a greater benefit on more clinically relevant cancer diagnoses.
Achieving and maintaining a healthy body weight, staying physically active, and following a healthy diet significantly reduced mortality in elderly female cancer survivors. Researchers found that adherence to lifestyle guidelines resulted in an almost 40% lower risk for death compared to those who did not follow these recommendations.
Scientists have identified a new type of stem cell that can generate new blood vessels, offering new possibilities for treating cardiovascular disease and cancer. The discovery could lead to the development of new therapeutics to prevent or stimulate neoangiogenesis.
A new study found that EMR before RFA is a safe and effective treatment option for patients with nodular Barrett's esophagus and advanced neoplasia. The performance of EMR before RFA was not associated with a diminished likelihood of success or increased stricture rate compared to RFA alone.
A common birth control device has been shown to be effective in treating early-stage endometrial cancer, particularly in morbidly obese and high-risk patients. The intrauterine device releases progestin levonorgestrel, successfully used as a contraceptive for the past decade, and successfully reversed abnormal cell growth in all patients.
A study published in the Journal of Thoracic Oncology found that fit elderly patients with non-small cell lung cancer can benefit from salvage targeted therapy without increased toxicity. The study analyzed data from 255 patients and showed no difference in response rates or progression-free survival between age groups.
Researchers at the University of Sheffield have found an antibody treatment that not only stops PAH from worsening but also reverses the condition in mice and rats. The discovery offers new hope for patients suffering from this devastating disease.
Researchers at UMass Amherst have found a way to deliver bio-active cargo such as proteins and synthetic molecules into naïve T cells using a new synthetic protein transduction domain. This breakthrough enables the study of crucial immune functions and holds great potential for therapeutic applications in the clinic.
A new study by TGen, Mayo Clinic and SHC demonstrated the power of whole genome sequencing in advancing understanding of pancreatic cancer. The research identified 142 cellular genetic coding events, including mutations, insertions and deletions, in three patients with pancreatic adenocarcinoma.
A new report reveals that mental illnesses and addictions have a significant impact on the health of Ontarians, with depression having the highest burden. The report highlights the need for treatment and reduced stigma to address this issue.
A new approach to lung scanning, called parametric response mapping, allows for better distinction between early-stage small airway disease and emphysema in patients with chronic obstructive pulmonary disease (COPD). The technique enables precise diagnosis and treatment planning, as well as tracking COPD progression over time.
Researchers found that B-Raf and C-Raf proteins are crucial for melanocyte stem cell renewal, leading to progressive whitening of fur in mice. The study provides insights into the role of these proteins in cancer development and offers potential new strategies for treating melanoma.
A new gene test has been developed to detect pre-cancerous cells in patients with benign-looking mouth lesions. The test shows a cancer detection rate of 91-94% and could potentially allow at-risk patients to receive earlier treatment, significantly improving their chance of survival.
A set of evidence-based clinical practice guidelines has been established to guide the diagnosis and treatment of low-back pain in the US. The guidelines recommend careful observation, over-the-counter pain medication, and targeted physical activity for most patients, while reserving imaging and surgery for specific cases with red flags.
A new study found that phone therapy is just as effective as in-person therapy for people with mild to moderate depression and anxiety. The research from the University of Cambridge also showed that providing talking therapies over the phone can save the NHS money, with a cost per session 36.2% lower.
Researchers at Karolinska Institutet have made a major breakthrough in type II diabetes treatment by inhibiting VEGF-B. The study shows that VEGF-B inhibition can prevent and treat insulin resistance, which is related to the storage of fat in muscles, blood vessels, and heart.
A nationwide study found that primary-care physicians earn an average of $2.8 million less than their specialist colleagues over a lifetime, potentially discouraging medical students from pursuing primary care. The study's authors recommend reducing pay disparities to ensure adequate access to primary care.
A Baylor University researcher has developed a model likening grief stages to a pinball machine, explaining why grieving is never complete and can be triggered by various events. The study uses the pinball analogy to help individuals in mourning understand their chaotic experience and prepare for future triggers.
A new study reveals that young cancer survivors frequently forego routine medical care because of financial constraints. Despite having health insurance, they face significant cost burdens, which can lead to unmet health needs.
A University of Colorado study shows that bladder cancer patients with high CD24 expression have worse prognoses and may benefit from anti-androgen therapies. CD24 expression depends on androgens, and blocking these hormones may diminish the proliferative and metastatic power of bladder cancer cells.
A new research model estimates that men with low-risk prostate cancer who choose active surveillance may live 6.4 years without treatment, while those who undergo immediate radical prostatectomy may gain an average of 1.8 months of additional life.
Researchers found that high viral load and cancer-specific viral gene expression are key markers for identifying HPV-driven tumors. These findings suggest that HPV DNA positivity alone is a poor predictor of outcome in head and neck cancers.
A new study by the University of Michigan Health System and VA Ann Arbor Healthcare System found a significant link between substance-use disorders and mortality in veterans with PTSD. Younger veterans, including those from Iraq and Afghanistan conflicts, showed a stronger association between substance-use disorders and death.
A significant reduction in the risk of developing diabetes was observed in individuals who underwent bariatric surgery compared to those receiving traditional care. The Swedish Obese Subjects study found that bariatric surgery can reduce the risk of diabetes by over 80% among obese patients.
Researchers found a single HPV protein necessary for cervical cancer and pre-cancer growths to survive. A gene-silencing technique may cripple the protein and eliminate cervical cancer and pre-cancerous growths in mice, offering a potential new treatment option.
Scientists at Uppsala University have successfully cloned a T-cell receptor that binds to an antigen associated with both prostate and breast cancers. This breakthrough enables genetically modified T cells to specifically kill these cancer cells, offering hope for new treatment possibilities.
Chemists at UMass Amherst have developed a sensor array system using gold nanoparticles and proteins that can rapidly detect and identify different cancer types in living tissue. The technology uses a 'nose' strategy similar to how humans recognize odors, allowing for precise detection of metastatic cells with high accuracy.
Researchers at UGA have made a major medical breakthrough by discovering how an oxygen-sensing bacterial protein senses oxygen through reversible structural changes in an iron-sulfur cluster. This mechanism could ultimately lead to a better understanding of the aging process and new treatments for human diseases.
A study published in American Journal of Pathology found that two genetic mutations, beta-catenin and insulin-like growth factor 2 (IGF-2), cooperate to induce adrenal cancer. The research provides new insights into the rare and deadly disease, which affects about 600 Americans annually, and may lead to targeted therapies.
The AAO-HNSF 2012 new poster presentations cover various topics in otolaryngology, including rhinoplasty, facial trauma, and head and neck cancer. The studies aim to improve treatment outcomes and address common challenges in the field.
A review article highlights the role of interleukin-18 (IL-18) in inflammation and its potential as a therapeutic target for pulmonary inflammatory diseases. Therapies blocking IL-18 activity may offer effective treatment options for conditions like bronchial asthma and COPD.
Researchers found that a medication inhibiting inflammation showed promise in treating major depression, especially in individuals with high levels of inflammation. The study employed infliximab, an antibody blocking tumor necrosis factor, and demonstrated improved symptoms in subjects with elevated C-reactive protein levels.
Researchers at Cleveland Clinic's Lerner Research Institute and Anesthesiology Institute have discovered a potential new treatment for Alzheimer's disease. The compound MDA7 has been shown to induce beneficial immune responses that limit the development of the disease, restoring cognition, memory, and synaptic plasticity in animal models.
A specific genetic variation found in people who carry a 'G' instead of an 'A' at a particular spot in their genetic code is associated with a six-fold higher risk of developing certain types of brain tumors. Researchers hope this discovery will lead to better surveillance and diagnosis.
A new study published in The Journal of Urology reports that PSA testing has led to improved survival rates for patients with newly diagnosed prostate cancer that has spread to the bones or other parts of the body. The disparity between African American and Caucasian men has been resolved, with African American men now having a compara...
A study published in European Journal of Epidemiology found that cancer survival rates in Germany have aligned significantly since reunification. While there are still slight differences, they have decreased compared to the pre-reunification era.
Researchers at the University of Strathclyde have developed a new approach to delivering green tea extract, epigallocatechin gallate, directly to tumors. In initial laboratory tests, nearly two-thirds of treated tumors shrank or disappeared within one month with no side effects to normal tissues.
Investigators found that low oxygen levels increase SMN2 exon 7 skipping, reducing survival motor neuron protein levels. Higher oxygen treatment improved motor function and reduced disease severity in a mouse model of severe SMA.
Researchers have successfully integrated RNA switches into viral genetic material to control gene expression, increasing the production of therapeutic genes by ten times. This technology has vast potential for various research and medical applications.
A retrospective study published in Archives of Dermatology found that patients with psoriasis treated with tumor necrosis factor (TNF) inhibitors have a significantly lower risk of heart attack compared to those not treated with TNF inhibitors. The study included 8,845 patients and adjusted for other MI risk factors.
The FastStitch device, developed by Johns Hopkins undergraduates, features a cross between a pliers and a hole-puncher to guide stitch placement and prevent accidental punctures. The device has already received recognition and funding to move forward, aiming to simplify and improve the closure process for surgeons.
Researchers found that B cells from patients with chronic GVHD are more active and resistant to programmed cell death. The study identifies BAFF as a promising target for developing new therapies, such as anti-BAFF agents or small molecule inhibitors.
The University of Delaware is part of a $2.5 million NIH-funded project to create artificial salivary glands. Researchers hope to develop new solutions for Xerostomia, a side effect of radiation treatment for head and neck cancers. The project involves developing hydrogels that can guide salivary cells to form functional glands.
Scientists have discovered that high iron levels can cause bowel cancer in people with a faulty gene, increasing the risk by two to three times. A diet low in iron prevents bowel cancer from developing altogether.
Researchers identified a previously unknown subtype of Ewing sarcoma with genetic factors related to long-term survival. A specific gene change between primary and metastatic stages may lead to better treatment.
Research finds that TRPM7 protein plays a critical role in breast cancer cell metastasis. High levels of TRPM7 expression are associated with poor patient outcomes and increased risk of distant metastases. The study suggests that targeting this protein could block metastasis, offering new therapeutic opportunities.
Researchers found tristetraprolin (TTP/ZFP36) to be a tumor suppressor that impairs lymphoma development and maintenance. The study's findings suggest TTP could be a key target for treating cancers with MYC involvement, including relapsed and refractory tumors.
A recent study in Pakistan found limited awareness of breast cancer among most women, with many unaware of self-breast exams and clinical breast exams. However, willingness to address health issues was high, and the majority of general practitioners understood major risk factors and importance of early detection.
Researchers found that herbal agents can prevent sunburn and limit UV damage, with golden serpent fern and Asian ginseng showing promising photoprotective properties when taken orally. Green tea applied topically also offers photoprotection in sufficient doses.
Researchers at Ohio State University found that liver cancer cells lose the ability to produce glucose due to microRNA-23a overexpression. Suppressing miR-23a might reverse this process and offer a new treatment for hepatocellular carcinoma, the most common form of liver cancer.
Two men with longstanding HIV infections have no detectable traces of HIV after bone marrow transplants, suggesting protection under anti-retroviral therapy. Researchers plan to study additional HIV-positive patients and explore tracing HIV in tissues.
Researchers from the British Columbia Cancer Research Center analyzed lung tumors exposed to arsenic, highlighting genetic and epigenetic changes driving carcinogenesis. These findings may help prevent arsenic-related cancer in regions with low exposure levels.
A meta-analysis of 10 studies found that cognitive behavioral therapy and pharmacologic interventions decrease depressive symptoms in cancer patients. The study also identified effective interventions for different stages of cancer and cultural subpopulations.
Directly targeting microRNA-125b to block androgen receptor activity represents a novel approach for treating castrate-resistant prostate cancer. The study provides new insight into the mechanism of miR-125b regulation of castrate-resistance prostate cancer.
The AACR-Kure It Grant will support innovative kidney cancer research, aiming to improve patient survival and quality of life. The grant recipient will receive $250,000 over two years and recognition at the AACR Annual Meeting.
Researchers at Stanford University have created a collection of compounds called bryologs that can activate latent HIV reservoirs with equal or greater potency than the original substance. The discovery holds promise as a practical way to flush out dormant viruses, offering hope for a cure for AIDS patients.
Researchers at Dana-Farber Cancer Institute have identified a new type of energy-burning fat cell, called 'beige fat,' which may have therapeutic potential for treating obesity and diabetes. Beige fat cells can burn off calories rather than store them, unlike 'white fat' cells.
A national survey of physicians found that patient fears and misinformation are major barriers to treating menopausal symptoms. The Endocrine Society has developed the Menopause Map, an online tool to guide women through treatment options and assess individual risk factors.
Researchers at HZDR demonstrate proton acceleration in the direction of the laser light, achieving unprecedented high energies. This breakthrough enables future cancer therapy applications with ultra-short pulse lasers.