A study found that the drug everolimus protects ovaries from cyclophosphamide, a common chemotherapy used against breast cancer, which depletes egg cells needed to achieve pregnancy. Female mice treated with everolimus and chemotherapy had more than twice as many offspring as those treated with chemotherapy alone.
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalProceedings of the National Academy of Sciences·DateMar 6, 2017
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Scientists have identified a metabolic weakness in triple-negative breast cancer cells that may be exploited to quell their resistance to chemotherapy. Targeting this pathway could lead to increased cancer cell death and improved treatment outcomes.
SourceLudwig Institute for Cancer Research·JournalCancer Discovery·DateMar 2, 2017
Researchers at Beth Israel Deaconess Medical Center have discovered a vulnerability in triple-negative breast cancer cells that can be exploited by blocking pyrimidine production. This finding provides a new strategy to combat the disease, which currently has limited treatment options.
SourceBeth Israel Deaconess Medical Center·JournalCancer Discovery·DateMar 2, 2017
A Phase III clinical trial revealed that blinatumomab significantly increased overall survival and remission rates compared to standard chemotherapy in patients with advanced acute lymphoblastic leukemia. The study showed a median survival of 7.7 months for those treated with blinatumomab versus four months for those on chemotherapy.
SourceUniversity of Texas M. D. Anderson Cancer Center·JournalNew England Journal of Medicine·DateMar 1, 2017
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Researchers developed a new treatment combining chemotherapy and immunotherapy to slow liver tumor growth in mice, with tumors growing 11 times smaller than in control groups. The study suggests that this approach could be translated to benefit patients with hepatocellular cancer, potentially extending and improving their quality of life.
SourceUniversity of Missouri-Columbia·JournalJournal of Hepatology·DateFeb 28, 2017
Researchers have shed new light on the molecular pump MRP1, which expels cancer drugs from cells. The pump's unique structure features two-part pocket allowing it to accommodate various substances.
Researchers found that nicotinamide riboside supplementation prevented nerve pain in rats treated with chemotherapy, which could lead to improved outcomes for patients. The supplement increased levels of NAD+, a cell metabolite that protects against nerve damage.
SourceUniversity of Iowa Health Care·JournalPain·DateFeb 23, 2017
Researchers at Johns Hopkins Medicine have identified a chain reaction that shields breast cancer stem cells from chemotherapy, making them resistant to treatment. The discovery could lead to the development of drugs that block this pathway, improving chemotherapy effectiveness.
SourceJohns Hopkins Medicine·JournalCell Reports·DateFeb 22, 2017
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A tool developed at UNC Lineberger Comprehensive Cancer Center can help doctors identify patients at high risk for toxic side effects from chemotherapy. Researchers found that low measures of muscle quality and quantity are linked to serious side effects, including hospitalizations.
SourceUNC Lineberger Comprehensive Cancer Center·JournalClinical Cancer Research·DateFeb 22, 2017
Researchers developed nanostraws that can sample a single cell at a time without damaging it, allowing for long-term non-destructive monitoring of cellular processes. This technique could inform cancer treatments and help develop patient-specific organs by understanding how stem cells evolve.
SourceStanford University·JournalProceedings of the National Academy of Sciences·DateFeb 21, 2017
A type of autologous hematopoietic stem cell transplantation (AHSCT) has been shown to slow or stop MS disease progression for up to five years in nearly half of patients, with significant benefits seen in younger patients and those with relapsing-remitting MS. However, the treatment carries a small risk of death and is not suitable fo...
SourceImperial College London·JournalJAMA Neurology·DateFeb 20, 2017
An international team of scientists has discovered the critical role of FtsZ filament motion in bacterial cell division, revealing a novel mechanism for building the cell wall. The study provides insights into the process and potential targets for new antibiotics.
A retrospective analysis of 1,424 patients found that those with an intermediate risk recurrence score (RS) had similar outcomes whether they received chemotherapy or not. The study suggests that less is more for women with early-stage disease, potentially leading to a shift away from aggressive treatment protocols.
SourceUniversity of Texas M. D. Anderson Cancer Center·JournalCancer·DateFeb 15, 2017
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A multicenter study found that scalp cooling reduced hair loss in certain breast cancer patients undergoing non-anthracycline adjuvant chemotherapy. The study, published in JAMA, showed that 67% of patients retained half or more of their hair after treatment.
Researchers at the University of British Columbia have developed a magnetic drug implant that can deliver precise doses of medication on demand. The device uses a magnet to trigger the release of drugs into surrounding tissue, offering a potential alternative to traditional pill or injection-based treatments.
SourceUniversity of British Columbia·JournalAdvanced Functional Materials·DateFeb 14, 2017
Two studies found that scalp cooling devices can significantly reduce hair loss in women with breast cancer undergoing chemotherapy. In one study, patients who received scalp cooling had an average of 51% hair preservation compared to 0% in the control group. The other study also showed promising results, with 67% of patients experienc...
A new UTSA study has found a potential link between a medication used to prevent infections in cancer patients and the regeneration of sperm from stem cells. Researchers discovered that G-CSF, a drug commonly used to recover from chemotherapy and radiation treatments, can also help restore male fertility.
SourceUniversity of Texas at San Antonio·JournalReproductive Biology and Endocrinology·DateFeb 13, 2017
In a groundbreaking study, 16 patients with severe aplastic anemia were successfully treated using partially matched bone marrow transplants followed by chemotherapy. After stopping immunosuppressive drugs over a year after their transplants, all patients showed no evidence of the disease.
SourceJohns Hopkins Medicine·JournalBiology of Blood and Marrow Transplantation·DateFeb 7, 2017
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
A new mathematical model reveals that metronomic chemotherapy's benefits rely on the normalization of tumor blood vessels, improving drug delivery and immune cell activity. The approach aims to alleviate abnormal tumor blood vessel structure and function, reducing proliferation of stem-like cancer cells.
SourceMassachusetts General Hospital·JournalProceedings of the National Academy of Sciences·DateFeb 6, 2017
Researchers have discovered a novel combination therapy that successfully treats infections caused by a pernicious form of antibiotic resistance. The treatment regimen, which includes ceftazidime/avibactam and aztreonam, overcomes the resistance caused by metallo-ß-lactamases, a growing global public health problem.
SourceAmerican Society for Microbiology·JournalAntimicrobial Agents and Chemotherapy·DateFeb 6, 2017
A new study found that 84% of patients with acute lymphocytic leukemia or their parents over-reported adherence to a regimen of 6-mercaptopurine, an oral maintenance therapy. Forgetfulness was the primary reason for non-adherence, and parental involvement improved adherence rates.
SourceAmerican Society of Hematology·JournalBlood·DateFeb 2, 2017
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
A new treatment approach uses a single dose of chemotherapy to select patients for chemo-radiation or surgery, resulting in near-80% survival rates. This method tailors treatments to individual tumor biology and patient characteristics, improving quality of life and reducing complications.
SourceMichigan Medicine - University of Michigan·DateFeb 2, 2017
Researchers have documented epigenetic changes in sperm of men who underwent chemotherapy in their teens, potentially affecting tissue health in subsequent generations. The study suggests that preserving sperm before undergoing chemotherapy may be necessary to mitigate these effects.
SourceWashington State University·JournalPLOS ONE·DateFeb 1, 2017
Researchers at SLU are working on a potential cure for hepatitis B, building on recent advances and partnering with experts in medicinal chemistry. The goal is to develop a new drug that can kill the virus, reducing levels to zero to cure patients.
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Researchers found a naturally occurring hormone, Mullerian Inhibiting Substance (MIS), can halt the development of ovarian follicles, protecting them from chemotherapy-induced damage. This reversible contraceptive method preserves the ovarian reserve and could be applied to modern fertility treatments.
SourceMassachusetts General Hospital·JournalProceedings of the National Academy of Sciences·DateJan 30, 2017
A new immunotherapy, pembrolizumab, has shown significant activity against mucosal melanoma tumors and prolonged survival in patients with bladder cancer. The treatment demonstrated a response rate of 16% and improved overall survival rates compared to chemotherapy.
SourceECCO-the European CanCer Organisation·DateJan 28, 2017
Younger patients with colon cancer are nearly 2 to 8 times more likely to receive postoperative chemotherapy than older patients, yet no added survival benefit is seen for these patients. The study's findings suggest overtreatment of young and middle-aged adults with colon cancer.
A UK-led clinical trial has successfully prolonged survival for pancreatic cancer patients by at least five years using a combination of chemotherapy drugs. The study found that patients who received this treatment had a 29% five-year survival rate compared to 16% for those on standard treatment.
SourceUniversity of Liverpool·JournalThe Lancet·DateJan 24, 2017
Inflammation in mice brains and spleens differed depending on when chemotherapy drugs were administered, according to Ohio State University researchers. The study's findings could lead to more effective treatment strategies and reduced side effects for cancer patients.
SourceOhio State University·JournalScientific Reports·DateJan 24, 2017
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Researchers found that African-American breast cancer patients who receive chemotherapy prior to surgery exhibit reduced regional and distant tumor recurrence rates. Early-stage patients with African-American ancestry display higher tumor recurrence rates compared to European-Americans.
SourceGeorgia State University·JournalPLOS ONE·DateJan 19, 2017
Researchers have identified multiple targets for Chagas disease chemotherapy, including ergosterol biosynthesis pathway and cruzipain, a key cysteine protease. Novel synthesized anti-T.cruzi compounds with specific single or multi-target assigned have also been described, highlighting potential for effective treatment.
SourceBentham Science Publishers·JournalRecent Patents on Anti-Infective Drug Discovery·DateJan 16, 2017
Researchers at the Buck Institute found that chemotherapy induces widespread cellular senescence, contributing to persistent inflammation and cancer recurrence. Eliminating senescent cells reduced side effects, including fatigue, bone marrow suppression, and toxicity, in mice treated with common chemotherapy drugs.
SourceBuck Institute for Research on Aging·JournalCancer Discovery·DateJan 16, 2017
Researchers from Goethe University Frankfurt discovered a novel biomarker, SAMHD1, that enables accurate prediction of therapy responders and non-responders in acute myeloid leukaemia (AML) patients. This biomarker can guide cytarabine-based chemotherapies to only those patients likely to respond, sparing others from toxic side effects.
SourceGoethe University Frankfurt·JournalNature Medicine·DateJan 10, 2017
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Scientists found that models with only two variables work best in combining drugs, reducing the risk of overfitting. The algorithm can be used to optimize various types of drug combinations, including those with multiple biological molecules.
SourceChinese Association of Automation·JournalIEEE/CAA Journal of Automatica Sinica·DateJan 10, 2017
A new Yale study suggests that delaying chemotherapy after lung cancer surgery can lead to similar outcomes and lower risk of death. The research found that initiation between 57-127 days post-surgery had a similar impact as traditional timing, indicating a potential benefit for patients.
SourceYale University·JournalJAMA Oncology·DateJan 5, 2017
A recent study published in JAMA Oncology suggests that chemotherapy can still benefit patients with non-small-cell lung cancer who recover slowly from surgery. The study found that delaying chemotherapy by up to four months did not increase the risk of death and may even lower it compared to earlier treatment.
SourceJAMA Network·JournalJAMA Oncology·DateJan 5, 2017
Researchers at UNC-Chapel Hill have developed a breakthrough technique that uses light to activate a drug stored in circulating red blood cells. This method could drastically reduce the amount of a drug needed to treat disease and thus side effects.
SourceUniversity of North Carolina at Chapel Hill·JournalAngewandte Chemie·DateJan 4, 2017
Researchers at Stanford University School of Medicine found that a subgroup of glioblastoma patients with highly vascularized tumors benefited from anti-angiogenic therapies, living an average of one year longer than those without. The study highlights the importance of properly categorizing tumors to personalize treatment.
SourceStanford Medicine·JournalNeuro-Oncology·DateDec 22, 2016
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Researchers found that localized chemotherapy delivered directly to the brain improved survival rates in mice with glioblastoma when combined with immunotherapy. The study suggests that systemic chemotherapy weakens the immune system and may hinder its ability to fight tumors.
SourceJohns Hopkins Medicine·JournalScience Translational Medicine·DateDec 22, 2016
Researchers developed a blood test to predict ovarian cancer patients' response to chemotherapy using tumour DNA levels. The test identified patients whose tumour DNA count dropped by more than half after one cycle of chemotherapy as those likely to respond well to treatment.
SourceCancer Research UK·JournalPLOS Medicine·DateDec 20, 2016
A routine blood test can predict how long cancer patients in palliative care will survive, researchers report. The Six Adaptable Prognostic models use three laboratory measurements to estimate death within 1-6 months, allowing physicians to re-evaluate prognosis at any time point.
SourceEuropean Society for Medical Oncology·DateDec 17, 2016
A study found that cancer patients with depression have lower levels of brain-derived neurotrophic factor (BDNF), making them less responsive to chemotherapy. Low BDNF levels are associated with reduced treatment tolerance and poorer outcomes.
SourceEuropean Society for Medical Oncology·DateDec 17, 2016
Researchers present first data on rare sarcomas in Asian patients, showing poor overall survival rates. Chemotherapy improves survival in advanced cases, but treatment rates remain low, with physician-related factors possibly at play.
SourceEuropean Society for Medical Oncology·DateDec 16, 2016
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers have identified a new way of blocking cancer cell invasion using calcium channel blockers, which can stop breast and pancreatic cancer from spreading. The team discovered that these drugs target the sticky finger-like structures on cancer cells, rendering them inactive.
SourceUniversity of Turku·JournalNature Communications·DateDec 16, 2016
A University of Alberta study found that proton pump inhibitors (PPIs) decrease capecitabine's effectiveness in gastric cancer treatment, reducing progression-free survival by over a month and overall survival by two months. PPIs can also affect colorectal cancer treatment efficacy.
SourceUniversity of Alberta Faculty of Medicine & Dentistry·JournalJAMA Oncology·DateDec 15, 2016
A new study from Lund University found that women with a high expression of the ER-beta estrogen receptor in their tumours had better outcomes after undergoing chemotherapy. The research could lead to more frequent check-ups and additional treatment for high-risk patients.
SourceLund University·JournalClinical Cancer Research·DateDec 15, 2016
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers have developed a lab device that enables early assessment of drug effects against cancer tumors, speeding up the adoption of therapeutically effective treatments. The microfluidic system allows for real-time monitoring of cell responses to drugs in a more accurate 3D model than traditional 2D cells.
SourceUniversity of Huddersfield·JournalScientific Reports·DateDec 15, 2016
Researchers review newly discovered anticancer molecules and their interactions with DNA, aiming to improve chemotherapy efficiency. New cancer treatment strategies also emerge, targeting tumor cell cycles and promoting apoptosis.
SourceBentham Science Publishers·JournalMedicinal Chemistry·DateDec 14, 2016
Patients with advanced non-small-cell lung cancer survived four months longer on immunotherapy drug atezolizumab compared to chemotherapy, with atezolizumab also having fewer side effects. The trial found that the drug worked best for patients with high levels of PD-L1 protein, doubling their survival.
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
The technology platform, Phenotypic Personalized Medicine, uses visual representations to identify optimal drug and dose combinations for patients with acute lymphoblastic leukemia. This approach reduces side effects while maintaining or enhancing efficacy, offering a game-changer for cancer treatment.
SourceUniversity of California - Los Angeles·JournalSLAS TECHNOLOGY·DateDec 12, 2016
A study presented at EuroEcho-Imaging 2016 found that chemotherapy caused heart damage in cancer patients with diabetes, leading to a higher risk of heart failure. The researchers also discovered that patients with diabetes experienced a significant decrease in global longitudinal strain, an early predictor of heart failure.
A new study at SABCS finds EndoPredict, a second-generation test, superior to Oncotype Dx in predicting breast cancer recurrence. The test accurately identified patients with low risk of recurrence, allowing them to forgo chemotherapy.
Supportive care, including pain relief and medication to prevent side effects, remains insufficient for many cancer patients, especially those on government-funded schemes in India. This can lead to delayed treatment cycles and poor quality of life. Researchers emphasize the need for better policies and access to effective treatments.
SourceEuropean Society for Medical Oncology·DateDec 7, 2016
Researchers at UNC Lineberger Comprehensive Cancer Center developed a model that can predict which triple negative breast cancer patients will respond to chemotherapy. The model was moderately successful, accurately predicting response in 68% of cases with pathologic complete response.
SourceUNC Lineberger Comprehensive Cancer Center·DateDec 7, 2016
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Patients with large breast tumors and no axillary lymph node signs before chemotherapy showed low risk of recurrence with SLNB. Follow-up data revealed high disease-free survival rates comparable to ALND, suggesting SLNB as a safe alternative.
SourceAmerican Association for Cancer Research·DateDec 7, 2016
The study found no difference in progression-free survival among patients receiving standard care, additional chemotherapy, or a second round of autoHCT. Researchers suggest that adding new therapies to the standard treatment may not provide significant benefits for patients with multiple myeloma.
A combination therapy of thioguanine and decitabine has shown promising results in a small Phase I clinical trial for patients with relapsed or refractory acute myeloid leukemia. Eight out of 12 patients responded to the treatment, including six who achieved complete remission.
SourceColumbia University Irving Medical Center·DateDec 5, 2016
A combination of brentuximab vedotin and nivolumab has been found to be safe and effective in treating recurrent Hodgkin lymphoma, with 64% of patients experiencing significant tumor reduction. The therapy has manageable side effects and shows promise as an alternative curative regimen for relapsed disease.
SourceNYU Langone Health / NYU Grossman School of Medicine·DateDec 5, 2016
Sky & Telescope Pocket Sky Atlas, 2nd Edition
Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
A Phase IB/II study found that combining nivolumab with azacitidine improved response rates (34%) and overall survival (9.3 months) in patients with acute myeloid leukemia, compared to a historic response rate of 12-15% with azacitidine alone.
SourceUniversity of Texas M. D. Anderson Cancer Center·DateDec 5, 2016
A proposed biosimilar drug has shown equivalent results to trastuzumab in treating metastatic breast cancer. The study's findings suggest that a biosimilar treatment option could increase global access to biologic cancer therapies, particularly for women in non-high-income countries.