Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
A new study found that a third of people with brain abnormalities similar to MS developed the disease within five years. Researchers monitored participants to determine whether they developed symptoms, and 30% had developed MS by average age 5.4 years.
Researchers investigate relationship between diabetes treatment and disordered eating behaviors in children with diabetes. They hope to find a different treatment approach that helps patients gain control over their eating behaviors and treatment without adopting maladaptive weight management strategies.
A new framework proposes national surveillance, monitoring, and research to inform future guideline development in low-income countries. Local data will optimize the management of childhood diseases like malaria, pneumonia, and diarrhoea by capturing country-specific differences.
A rectal application of artesunate may be the key to saving lives from severe malaria in remote areas. The study found that pre-referral rectal artesunate significantly reduced mortality and permanent disability among patients with suspected severe malaria who could not receive oral treatment.
Research finds that progressive lung damage in CF patients can begin as early as infancy, even if lung function is normal shortly after diagnosis. Early intervention in the first six months of life may be key to slowing disease progression.
A new study by researchers at Duke University Medical Center found that over half of fertility patients are against implanting stored embryos in others, highlighting concerns about embryo disposition. The study surveyed over 1,000 patients and revealed previously unexplored concerns about their embryos.
A new method for determining osteoporosis treatment targets has been developed using the WHO's fracture risk assessment tool, FRAX¹. This approach considers both fracture risk and cost-effectiveness to provide more accurate and targeted treatment.
A randomized clinical trial found that CPAP treatment improved cognitive functioning in patients with mild to moderate Alzheimer's disease and obstructive sleep apnea. The study showed significant improvement in neurological test scores after treatment, suggesting clinicians should consider implementing CPAP treatment for these patients.
A study of 387 patients found that 43% developed postthrombotic syndrome, a long-term complication not addressed by traditional treatment approaches. The risk factors identified include age, previous DVT, and larger blood clots at diagnosis.
A Swedish study suggests that test-tube babies can be a profitable investment for states due to increased population and tax revenue. In the long term, the state benefits from subsidizing IVF treatment for involuntarily childless couples, which could potentially help boost population growth.
A new ultrasound-guided technique combined with steroid injection has been shown to be 95% effective in relieving plantar fasciitis symptoms within three weeks. This treatment is a viable option for patients who have tried conservative treatments and are experiencing persistent pain.
Vasovagal syncope is a common emergency situation in dental offices, characterized by loss of consciousness and muscle tone. Patients experiencing symptoms such as dizziness, lightheadedness, or pain may have an underlying cause that can lead to a life-threatening situation.
Telcagepant has shown efficacy in treating moderate to severe migraines, offering a safer alternative to triptans with fewer side effects. The study analyzed 1380 patients and found telcagepant 300mg to be more effective than placebo for freedom from pain and other symptoms.
Researchers found that training individuals to read body language, facial expressions, and voice tone in others resulted in significant gains in emotional perception. This skill is crucial for successful social communication and helps overcome chronic social difficulties or isolation. The training regime, known as self-instruction trai...
A study found that doctors are unsure about the legality of deactivating an implantable cardioverter-defibrillator (ICD) in terminally-ill patients, leading to unnecessary pain. The researchers recommend educating physicians on managing end-of-life care for ICD patients.
Patients with serious anxiety disorders tend to report more intense physiological symptoms than they actually experience, according to a new study. Physiological tests revealed that these patients are often hyporeactive, contradicting their self-reported symptoms.
A new IBS treatment developed at University at Buffalo has received $8.5 million to conduct a seven-year, multi-site clinical trial of the program. The trial will test the long-term effectiveness of a self-administered cognitive behavior therapy program and assess its impact on quality of life.
A study published at the American Heart Association's Scientific Sessions reveals a common genetic variation associated with an increased risk of heart events. The discovery enables better prediction of individual risk and informs more targeted treatment approaches.
Researchers will investigate new ways of developing clinical trials for Alzheimer's disease and Parkinson's disease. The study aims to improve the speed, cost-effectiveness, and relevance of treatments, benefiting patients and their carers.
A meta-analysis of 33 trials found no significant reduction in mortality risk with beta-blockers in non-cardiac surgery patients, but did reduce heart attack and vessel blockage risk; however, it also increased stroke risk. The authors call for reevaluation of guidelines until conclusive evidence is available.
According to a study published in Archives of Neurology, only about half of patients with multiple sclerosis (MS) achieve and maintain a response to interferon beta treatment over three years. Regular MRI evaluations show that many patients experience worsening disease despite treatment.
Despite its biblical origins, leprosy remains a significant public health concern in the US, with approximately 150 cases diagnosed annually. Early treatment with medicine is crucial for full recovery, but misdiagnosis and lack of awareness among physicians lead to delayed treatment and debilitating damage.
A new study reveals that substance abuse disorders (SUDs) and other psychiatric disorders are prevalent among French prisoners. Dual diagnosis (DD), a co-existence of SUD and any Axis I disorder, is a major risk factor for suicide, with mood and anxiety disorders being the most frequent disorders found in DD prisoners.
A study of 110 patients found that brain edema, known as perilesional oedema (PO), is common and associated with seizures in patients with calcified neurocysticercosis. PO may be a preventable cause of seizures in endemic countries, suggesting a unique treatment target.
The International Osteoporosis Foundation backs the National Osteoporosis Society in criticizing NICE guidance on osteoporosis prevention and treatment. Key concerns include women's access to effective treatments, exclusion of high-risk men, and lack of incorporation of the WHO-supported Fracture Risk Assessment Tool.
Research at Mayo Clinic suggests that teaching children to face their fears can improve functioning and complete exercises exposing them to their fears earlier than recommended treatment manuals. In contrast, focusing solely on managing anxieties yields less improvement.
The WVU study demonstrates that CT perfusion imaging can diagnose acute ischemic stroke with high accuracy, particularly for major vessel occlusion strokes. The technology allows for fast and targeted treatment, reducing the risk of life-threatening complications.
A new study explores how men and women perceive online and offline sexual and emotional infidelity, finding that men felt sexual infidelity was more upsetting and women felt emotional infidelity was more upsetting. The results also reveal differences in beliefs about sex and love between men and women.
A new protocol, PAST, reduces pre-hospital delays for stroke patients, increasing those treated with thrombolytic therapy from 4.7% to 21.4%. The protocol could save an estimated $31.2 million annually by enabling more patients to receive brain-saving treatment within the three-hour window.
The Lancet Series on Health System Reform in China discusses the need for an efficacy-driven approach in traditional Chinese medicine (TCM) research. Poor people rely heavily on herbal medicine, but many treatments lack reliable evidence of efficacy, exacerbating healthcare inequity.
A new study found that office-based vision therapy by a trained therapist, along with at-home reinforcement, is more effective in treating convergence insufficiency (CI) in children than traditional home-based therapy. The treatment resulted in reduced symptoms and improved vision in nearly 75% of participants.
The minimally invasive endograft procedure enables doctors to fix the artery without making an incision, reducing blood loss and recovery time. This innovative approach has evolved treatment options for blunt aortic injury, stabilizing the injured artery and offering a life-saving option for patients with multiple traumatic injuries.
New research identifies key factor in treatment delay: flock management philosophy. Early identification and individualized treatment of footrot can reduce lameness incidence by up to 80%. The study suggests farmers have the skills to follow best practices but may need resources to implement them.
A study by Cedars-Sinai cardiologists suggests that evidence-based reimbursement incentives can lead to significant economic savings in healthcare. By prioritizing medical procedures with proven effectiveness, doctors and hospitals can help reduce costs without compromising patient care.
A study found that farmers are skilled at identifying mildly lame sheep, but often neglect to treat them promptly, allowing the disease to spread. The researchers recommend that farmers inspect and treat the first mildly lame sheep in a group within one to three days of it first being lame
The study found that more Americans are living with hypertension, rather than dying from it. Treatment and control rates have improved, especially among men and certain ethnic groups.
Researchers at Northwestern University believe spicy food, including pepperoni pizza, can worsen pelvic pain and urinary frequency in women with interstitial cystitis. A new treatment approach using anesthetic patches or suppositories may provide relief.
A study published in The Lancet Neurology found that patients in a minimally conscious state may experience pain perception similar to healthy individuals. This suggests that these patients could benefit from painkilling treatment, which is currently challenging due to limited awareness of their condition.
The 'Rolling Back Malaria' partnership has announced a comprehensive plan to control and eradicate malaria, targeting short-term reduction of mortality and morbidity by half by 2010 and long-term elimination of transmission. The plan is estimated to save 4.2 million lives in Africa, but requires $62 billion in funding by 2020.
A study found that CT scans changed the initial treatment plans of emergency physicians in over 29% of patients with suspected appendicitis. This alteration was largely due to CT results ruling out appendicitis when surgical consultation was initially recommended, reducing unnecessary surgeries.
Research by Dr. J. Donald Richardson found that deployed peacekeeping veterans with PTSD experience significant impairments in health-related quality of life. The study highlights the importance of assessing quality of life when evaluating veterans for rehabilitation needs.
A new study found that severe esophageal damage is rare in asymptomatic children after caustic ingestion. The study concluded that an endoscopy should be performed in all symptomatic patients to predict esophageal lesions and prevent complications.
A study by Dr. David Spence found that 95% of patients with asymptomatic carotid stenosis can manage without surgery, benefiting from improved medical treatment and lifestyle modifications. Patients with microemboli are the exception, requiring revascularization to reduce stroke risk
The DIRECT studies found that candesartan can reduce the incidence of retinopathy in type 1 diabetes and increase its regression in type 2 diabetes. The treatment also showed a significant reduction in risk of progression by three or more steps on the EDTRS scale.
Bisphosphonate osteonecrosis, a debilitating jaw condition, affects millions of seniors taking osteoporosis treatments. The American Academy of Otolaryngology warns of this risk, which can cause pain, swelling, and loose teeth.
Scientists at National Space Biomedical Research Institute (NSBRI) are developing an interactive, multi-media program to assist astronauts in recognizing and managing depression. The system, part of the Virtual Space Station, provides a straightforward process for problem-solving and goal-setting, with features including graphics, vide...
A new study finds that among seniors with voice and swallowing issues, only 20% actually seek treatment. Researchers call for increased awareness and outreach programs to address these impairments among the elderly, who may experience depression, anxiety, and social withdrawal due to untreated voice and swallowing problems.
Nearly 20% of octogenarians studied had dysphonia, while 14% experienced painful swallowing. Despite expressing interest in treatment, many seniors lacked awareness and received inadequate care from primary care physicians. The study highlights the need for better education to improve quality of life outcomes.
A new study found that measuring exhaled nitric oxide in adolescents with asthma did not improve disease control. Despite initial improvements, participants who received treatment with exhaled NO monitoring had similar asthma symptoms and exacerbations as those without
A novel clinical trial will compare online CBT with face-to-face group therapy for treating bulimia nervosa. The study aims to test the effectiveness of CBT4BN and reduce attrition rates among participants.
Darapladib's Lp-PLA2 inhibition prevents necrotic core expansion and plaque vulnerability in patients with coronary disease. Despite high standard care treatment, placebo-treated patients showed increased necrotic core volume, while daraplidib halted this increase.
Researchers found that depression subtypes differ in cardiotoxicity and response to antidepressive treatment, with somatic and incident depressions associated with poor prognosis. This knowledge could lead to new treatment strategies to prevent future cardiac events.
The study provides an accurate picture of XXYY syndrome, identifying unique medical and psychological characteristics, including cardiac abnormalities, dental problems, and learning disabilities. Treatment recommendations focus on targeted therapies for behaviors, emotional problems, and community services to support independent living.
A survey of trauma professionals and the general public reveals differing opinions on end-of-life care following severe injuries. While both groups prefer palliative care, there are disparities in views on patients' rights to demand care and the role of divine intervention.
Anemia of chronic disease could be an adaptive response to inflammatory illness, rather than a disorder. Researchers suggest treating mild to moderate cases to avoid increased mortality from treatment.
A recent study found significant racial, age and geographic disparities in the use of cardiac resynchronization therapy (CRT), a treatment for heart failure. The research examined nearly 34,000 hospital admissions and discovered that CRT was underutilized in certain populations, such as older patients and those from the Northeast.
A study by Indiana University researchers reveals a significant communication gap between older adults and their surgeons, with only half of concerns discussed during consultations. This mismatch can lead to poorly tailored treatment recommendations, emphasizing the need for effective communication.
Researchers at OHSU discovered males from a strain of mice called MRL/MpJ have the innate ability to repair their own knee cartilage. Cartilage injuries heal poorly in humans, leading to osteoarthritis, which affects one quarter of the adult population by 2020.
Researchers have induced pre-eclampsia in mice by injecting human autoantibodies, demonstrating a potential pathway for the disorder. Blocking these autoantibodies prevented the development of pre-eclampsia in mice, suggesting a new approach to diagnosis and treatment.
The special issue highlights promising therapeutic targets and techniques to measure the effects of disease-modifying therapies on cerebral amyloid β levels. Clinical trials are underway, and several promising drugs are headed towards clinical trials, offering cautious optimism for new AD therapeutics.