A new review found that one-third of children with chronic pain also meet the criteria for an anxiety disorder, while one in eight meets the criteria for a depressive disorder. The study suggests that clinicians should consider screening for mental health issues when treating young patients with chronic pain.
A new study reveals that mindfulness meditation reduces pain intensity and unpleasantness ratings by directly modifying how we experience pain. Unlike the placebo cream, which only affects brain activity patterns associated with the placebo effect, mindfulness meditation employs a separate neural pathway to alleviate pain.
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Researchers at the University of Utah developed Diadem, a noninvasive device that stimulates deep brain regions to disrupt faulty signals causing chronic pain. In a recent clinical trial, participants experienced significant pain relief after just one treatment session.
A new UBC Okanagan study emphasizes the importance of identifying and managing neuropathic pain in high-performance athletes with spinal cord injuries. The research stresses the need for sports medicine clinicians and trainers to use standardized assessment tools, including symptom-based questionnaires, to better understand and communi...
A randomized clinical trial tested the effectiveness of two eight-week telehealth mindfulness-based interventions, finding they improved pain and overall well-being among veterans with chronic pain. The scalable format made it accessible for patients, suggesting a potential solution to accelerate non-medication pain treatment.
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Scalable telehealth mindfulness-based interventions show promise in treating chronic pain by improving function and reducing symptoms. The low-resource approach could accelerate the adoption of nonpharmacological pain treatment in healthcare systems.
A review of 148 studies found nearly one in ten patients experience opioid dependence or disorder, while nearly one in three show symptoms. The study emphasizes the need for accurate estimates to develop effective interventions and manage the problem.
Mark Lumley, a distinguished professor at Wayne State University, received the 2024 Nathan W. Perry Jr. Award for Career Service to Health Psychology. He was recognized for his decades-long contributions to the field of health psychology, particularly in chronic pain disorders.
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A new study uses artificial intelligence to predict which breast cancer patients are most at risk for developing chronic pain, with anxiety and depression being leading factors. The AI model was built with detailed data on over 1,000 breast cancer patients and correctly predicted chronic pain more than 80% of the time.
Researchers found that adults with chronic pain experience higher rates of anxiety and depression but access mental health care at lower rates. Only 44.4% of those with chronic pain received adequate treatment for their symptoms, compared to 71.5% without chronic pain.
Researchers identified a viable path to developing a novel therapy that would make opioids more effective and safer as a treatment for chronic pain. The study found that selective Hsp90 inhibitors amplified the pain-relieving effects of morphine, reducing tolerance and side effects.
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A cross-sectional study of CTE patients found that years of contact sports participation are linked to substantia nigra pathology, leading to parkinsonism. The study suggests that repetitive head impacts may trigger neuropathologic processes in individuals with CTE.
Researchers found that a specific gene variation in women with chronic pelvic pain makes them more likely to respond to the medication gabapentin. The study could lead to tailored treatment and minimize adverse effects for millions of women worldwide.
A new study found that surgical weight loss significantly reduces widespread pain in Black and Hispanic patients, with the greatest benefit seen within the first three months after surgery. However, disparities persist, with these groups still experiencing a higher pain burden than the general population.
A team of researchers has identified the PIEZO2 protein as a critical mediator of sensory signals that maintain chronic pain. The study found that gain-of-function mutations in the PIEZO2 gene can mimic the effects of chronic pain in C-fibers, suggesting a new target for pain medication.
A new study reveals that military women and female family members face significantly higher risks of chronic pain, with those serving during periods of heightened combat deployments facing a 53% higher likelihood of developing the condition. The study also found associations between chronic pain, mental health, and socioeconomic status.
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A study led by UCLA Health found that emotional awareness and expression therapy (EAET) significantly reduces chronic pain among older adults compared to cognitive behavioral therapy. EAET helps patients confront and release traumatic emotions, leading to a clinically significant reduction in pain symptoms.
A study by the University of Toronto found that 43% of Canadians with a history of bipolar disorder were symptom-free and 23.5% had achieved complete mental health. Factors contributing to psychological flourishing included having a trusted confidant, using spirituality as coping mechanisms, and absence of disabling chronic pain.
A recent study published in BRAIN found that males and females differ in their experience of pain due to functional sex differences in nociceptors. The findings support the implementation of a precision medicine-based approach considering patient sex as fundamental to treatment choices.
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A case report describes the successful use of thoracic paravertebral blocking to manage severe chronic pain associated with post-herpetic neuralgia. The procedure, involving repeated injections of levobupivacaine and dexamethasone, resulted in significant pain subsidence and reduced medication needs.
Researchers found that five cannabis terpenes reduced chronic neuropathic pain levels comparable to morphine. The combination of terpenes and morphine enhanced pain relief without negative side effects. Terpenes offer an alternative to opioids for pain management with a better side effect profile.
A team of visionaries at the Carney Institute developed 3D-printed brain and spinal cord implants, revolutionizing surgical implantations and optical access. Bioluminescence imaging overcomes limitations of traditional fluorescent microscopy, providing unprecedented observation of neural and vascular activity.
A recent study in Brazil found that over 27% of children and adolescents suffer from musculoskeletal pain, with back and leg pain being the most common complaints. The study highlights the need for better understanding and planning of public health policy regarding treatment of chronic pain in adults.
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Researchers developed tiny, flexible devices that can wrap around individual nerve fibers without damaging them. The robotic nerve cuffs are sensitive enough to grasp delicate nerves and only require tiny voltages to change shape.
A new study establishes official climate divisions in Hawaii, improving climate research and forecasting. Chronic pain sufferers who spend time outdoors experience stronger weather-based effects, while lightning-initiated wildfires are responsible for more than half the acres burned in the contiguous United States.
A new study found that people from lower socioeconomic backgrounds are twice as likely to develop chronic musculoskeletal pain following an injury. The researchers identified several factors, including smoking, fear of movement, and poorer support networks, that contribute to the development of chronic pain.
A study of 1,470 adults with chronic low back pain found that physician empathy was associated with improved outcomes over 12 months. Greater efforts to cultivate and improve physician empathy are warranted.
Researchers at the University of Alabama at Birmingham found that blocking Tiam1 activity in spinal neurons abrogates morphine tolerance and hyperalgesia in a mouse model. Prolonged morphine treatment increased activated Tiam1 levels, leading to dendritic spine morphological changes.
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A study of over 10,000 adults found that physical activity is associated with a lower risk of chronic pain and reduced severe pain severity. Higher activity levels are linked to increased pain tolerance, which explains the protective effect.
A recent study published in The Journal of Pain has found that CBD products are ineffective in reducing chronic pain and may pose health risks. The research, led by the University of Bath, examined existing studies on CBD and concluded that there is no quality evidence to support its use as a pain reliever.
Researchers at Xi'an Jiaotong-Liverpool University developed a new method that enables the efficient production of cysteine-rich peptides and microproteins in their naturally folded 3D structure. The approach uses organic solvents to mimic nature's oxidative folding process, resulting in speeds of over 100,000 times faster than aqueous...
A two-question survey identifies patients at risk of poor pain outcomes, who are then steered to holistic services with significant reductions in morphine dose. Holistic interventions, including pain management and behavioral health programs, lead to better outcomes than traditional chronic pain management approaches.
A study of 1,156 individuals aged 50+ found that those with more musculoskeletal pain complaints tended to retire earlier than pain-free participants. Chronic pain was also linked to a higher risk of ceasing work sooner, even after controlling for other factors.
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A new study from the University of Portsmouth found that people with musculoskeletal pain complaints tend to retire earlier compared to pain-free participants. Participants suffering from musculoskeletal pain were also 1.25 times more likely to cease work sooner, whether or not they described themselves as retired.
A new study by UArizona Health Sciences researchers found that sleep disturbances increase the vulnerability to migraine attacks. Improving sleep health may decrease the likelihood of migraine attacks in people with migraine. The study used preclinical mouse models and found no link between migraine-like pain and disrupted sleep.
A new study led by Worcester Polytechnic Institute aims to determine whether AI can help doctors predict which patients will benefit from mindfulness-based stress reduction in managing chronic lower back pain. The research uses machine learning and physiological data from fitness sensors to detect patterns that may not be apparent to d...
A recent article recommends measuring meaningful outcomes such as pain interference, self-efficacy, and physical functioning to improve the evidence-base for music therapy within sickle cell disease populations. Music therapists can play an important role in chronic pain management by addressing stress, depressed mood, and loneliness.
A recent survey of Norwegian adults found that one in eight individuals who underwent cosmetic surgery experienced chronic post-operative pain. The study highlights the increasing popularity of cosmetic procedures and the need for better awareness about potential complications, including chronic pain.
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Researchers investigate the effectiveness and safety of the Angel Touch device (AT-04) in managing endometriosis-related pain. The study, led by Associate Professor Hiroshi Ishikawa at Chiba University, aims to assess the device's ability to alleviate pain and improve quality of life for women with the condition.
Researchers at Virginia Tech's Fralin Biomedical Research Institute found applying low-intensity focused ultrasound to the brain can reduce pain perception, brain activity, and cardiac responses. The non-invasive technique may provide a new therapeutic option for chronic pain treatment.
Researchers at University Hospitals Cleveland Medical Center developed a quality improvement project using routine pain screening, revealing 32.7% of patients reported persistent or chronic pain, with music therapy and art therapy preferred for managing pain.
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Researchers used low-intensity focused ultrasound to target the insula, a brain region associated with pain processing. The study found that participants experienced an average reduction in pain of three-fourths of a point, as well as decreased physical responses to pain-induced stress.
Researchers found that the brain's pain modulatory system changes with age and gender, making females more sensitive to moderate pain as they get older. The study used fMRI scans to examine brain responses in men and women aged 30-86 and identified a key role for the descending pain modulatory system.
A recent study found disparities in access to integrative health and medicine, as well as nonpharmacologic therapies, among vulnerable populations with chronic pain. These findings highlight the need for policy changes to promote equitable access to these evidence-based modalities.
Gabapentinoid usage has continued to rise in the US, increasing from 4.0% in 2015 to 4.7% in 2021, according to a recent report. The study found that users continue to take these medications despite FDA warnings against combining them with other sedating medications.
A new Northwestern Medicine study found that opioid prescription limits are effective in reducing prescription length when set according to the type of doctor visit. The study, which analyzed data from West Virginia from 2017-2019, showed a significant reduction in prescription lengths for patients in hospital and outpatient settings.
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A clinical trial found that trazodone and cognitive behavioral therapy for insomnia were no more effective than placebo in improving insomnia symptoms among long-term dialysis patients. Serious adverse events also occurred more frequently with trazodone use. More trials are needed to investigate additional therapies for this condition.
A recent study from the University of Georgia found that over 70% of respondents with chronic pain would alter their daily plans based on weather-based pain forecasts. The study suggests that developing a reliable pain-based weather forecast could help individuals take preventative measures to manage their pain levels.
A nationwide Danish study found a slightly increased risk of arrhythmia in patients taking medical cannabis for chronic pain. The risk was more than twice that of those not receiving cannabis, with the largest increases observed in older adults and those with pre-existing cardiovascular conditions.
Research from Michigan Medicine found that widespread pain with nociplastic features can make physical activity challenging for patients with multiple sclerosis. The study suggests tailoring exercise plans to individual needs by considering underlying pain mechanisms, aiming to maintain functional independence and reduce pain intensity.
A new study published in The Journal of Head Trauma Rehabilitation found that approximately 60% of people living with traumatic brain injury (TBI) experience chronic pain, even up to 30 years after injury. Chronic pain can significantly worsen outcomes for individuals with TBI, and medications are often the most frequently used treatment.
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A systematic review and meta-analysis found that individuals exposed to childhood trauma are at an increased risk of experiencing chronic pain and pain-related disability in adulthood. The study highlights the urgent need for targeted interventions to address adverse childhood experiences.
Researchers have developed a spinal cord stimulation technology that restores sensation, improves function, and reduces phantom limb pain after trans-tibial amputation. The study showed significant improvements in balance control and gait stability, with an average 70% reduction in phantom limb pain.
A new U-M study found that 72% of adults in the US have heard of CBD, while fewer are aware of other hemp-derived cannabinoids like delta-8-THC and CBG. The products' lack of regulation and inadequate safety testing pose health risks to consumers, especially young people.
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A randomized clinical trial found that Mindfulness-Oriented Recovery Enhancement (MORE) plus usual care significantly decreased drug use, pain, and depression in individuals with opioid use disorder and chronic pain. Participants who received MORE also showed increased methadone treatment retention and adherence.
A study of over 20,000 middle-aged US adults found lower income status linked to increased hypertension risk. Higher-income adults faced rising rates of diabetes and obesity. Targeted public health initiatives are needed to address growing cardiovascular mortality among middle-aged adults.
A new study highlights the need for increased awareness and vigilance among medical professionals in addressing chronic pain dependency. Patients describe feeling ignored and misunderstood, leading to feelings of shame and guilt.
Researchers have identified a small molecule that reverses four types of chronic pain in animal studies without troublesome side effects. The compound, CBD3063, binds to the inner region of a calcium channel, indirectly regulating its activity and reducing neurotransmitter release.
A recent study found that transient inflammatory pain causes persistent mitochondrial and metabolic disturbances in sensory neurons, leading to failure in pain resolution. Targeting the cellular redox balance prevents and treats chronic inflammatory pain in rodents.
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A new study will test a two-step music therapy intervention to reduce pain, anxiety, and depression in veteran patients. The research aims to assess the cost-effectiveness of step 1 music listening and step 2 music imagery interventions.