Articles tagged with Diabetes
Researchers identified a molecular 'switch' controlling skin cell migration necessary for wound closure and healing. The discovery may hold the key to developing therapeutics that reduce or prevent chronic wounds.
Researchers at BUSM found that cognitive behavioral therapy (CBT) can relieve pain for people with painful diabetic neuropathies. CBT, a psychological treatment approach, was compared to treatment as usual in a study of veterans with type II diabetes.
A Harvard T.H. Chan School of Public Health study found significant public support for government actions to address obesity and noncommunicable diseases, particularly those promoting healthy choices. Support was highest for menu labeling requirements and lower for penalizing certain behaviors or health conditions.
A Kaiser Permanente study of over 40,000 patients found no significant increase in surgical complications for those with diabetes. Despite previous findings suggesting a higher risk, researchers discovered better glycemic control among study participants reduced the impact of diabetes on surgery outcomes.
A recent review of 400 patients with Wolfram syndrome reveals that 15% do not meet current diagnostic criteria, highlighting the need for revision. The study proposes expanding the diagnostic criteria to identify two of four clinical features, which would diagnose up to 98% of patients.
A study of over 40,000 Kaiser Permanente patients found no increased risk of infection or complications following total knee replacement (TKR) for those with diabetes. However, patients with uncontrolled diabetes were more likely to be obese and have severe comorbidities.
A large epidemiological study found that increased sugar availability was linked to higher diabetes rates, independent of obesity. The researchers analyzed data from 175 countries and found a 1% increase in diabetes prevalence for every additional 150 calories of sugar per person per day.
A recent study published in the BMJ found that home-based telehealth had no effect on quality of life, anxiety, or depressive symptoms for patients with chronic conditions. The study, which involved over 1,500 participants, suggests that concerns about telehealth's potential benefits are unfounded.
A unique study highlights the importance of universal newborn screening for congenital adrenal hyperplasia (CAH), a life-threatening disorder affecting cortisol production. Screening improves survival in both boys and girls, contradicting previous beliefs that boys were at higher risk of delayed diagnosis.
A study published in Population Health Management found that eliminating co-payments for diabetes-related medications and supplies improved patient self-management of their condition. Nearly 90% of participants reported better disease management after the program's initiation.
A study published in the International Journal of Behavioral Nutrition and Physical Activity found that sitting time was significantly associated with an increased risk of chronic diseases. The study, which included 63,048 middle-aged Australian males, showed a steady increase in risk as sitting time increased.
A new University of Iowa study suggests that diabetes may be linked to an increased risk of death from heart attacks due to the over-activation of a key enzyme. In diabetic mice, this enzyme's activation led to abnormal heart rhythms and an elevated risk of sudden death.
Diabetic patients are more likely to die from a heart attack, and high levels of ox-CaMKII may be the key. Researchers found that reducing CamKII oxidation could help treat diabetic patients with cardiovascular disease.
Researchers at Queen's University Belfast are developing a novel approach to repair damaged blood vessels in the retina using adult stem cells. This innovative therapy has the potential to prevent and/or reverse diabetic retinopathy, reducing the risk of vision loss.
The Gulf region is expected to experience a massive wave of cardiovascular disease in the next 10-15 years, driven by high obesity rates and diabetes prevalence. Prevention services are lacking, but experts call for a public health strategy to promote physical activity and healthy diets.
Researchers at Boston Children's Hospital used a social networking approach to investigate the magnitude of hypoglycemia and promote healthy behaviors among participants with diabetes. The study showed that engaging patients in research through social media can help augment traditional surveillance methods and lead to meaningful behavi...
A team of researchers at the University of Michigan's Life Sciences Institute has found that amlexanox, an off-patent drug, can reverse obesity, diabetes, and fatty liver in mice. The study suggests that the drug works by inhibiting two genes involved in metabolic balance, leading to increased metabolism and weight loss.
A recent study found that nearly 8% of stroke survivors in the US contemplate suicide, with risk factors including depression, age, and socioeconomic status. Regular screening for suicidal ideation is recommended to address this often-overlooked concern.
Researchers found that late eaters lost significantly less weight and had a slower rate of weight-loss, suggesting the timing of large meals is an important factor. However, the timing of smaller meals did not play a role in weight loss success.
A Kaiser Permanente study of 26,000 patients with diabetes found that controlling blood pressure and cholesterol is crucial in preventing heart disease. Patients who met guidelines for all three risk factors had a significantly lower rate of hospitalization for heart attack or stroke.
Researchers found a protective association between beta carotene and type-2 diabetes risk in individuals carrying a common genetic predisposition. In contrast, gamma tocopherol was linked to an increased risk of the disease. The study suggests that protein SLC30A4 may play a crucial role in insulin regulation.
Researchers at Umeå University have developed a new imaging method using optical projection tomography (OPT) in the near-infrared spectrum to study insulin-producing cells in diabetes. This technology allows for the examination of larger organs, including the rat pancreas, and can track specific cell types simultaneously.
Researchers discover that belly and thigh fat differ significantly in gene expression, with unique homeobox genes influencing fat cell behavior. This finding may lead to targeted treatments for obesity, shifting focus from belly fat to hip and thigh fat.
Researchers found abnormal proteins in gluteal fat, which secretes chemerin and reduces omentin-1 levels. These proteins correlate with increased inflammation, insulin resistance, and heart disease risk. The study dispels the myth that pear-shaped bodies are healthier than apple-shaped ones.
A team of researchers from Case Western Reserve University School of Medicine has discovered the definitive answer to how insulin binds to cells. This breakthrough could lead to dramatic improvements in treating diabetes, including alternative oral medications and fewer injections per day.
NYU's Strauss is awarded NIH grant to develop a novel approach using oral blood to screen patients with periodontal disease for diabetes in general dental practices. The study aims to assess the accuracy, acceptability, and feasibility of this approach.
A new study found that adults with diabetes in Ontario are getting significantly fewer government-funded eye exams than they were a decade ago. The decrease is an unintended consequence of the provincial government's decision in 2004 to delist routine eye exams from the Ontario Health Insurance Plan for healthy adults under age 65.
A recent study by UCSF researchers found that patients who receive high-quality communication from their doctors are more likely to fill their prescriptions. The study of 9,377 patients showed that effective communication leads to better medication adherence rates, with a 4-6% lower rate for those who felt heard and trusted.
Researchers identified three genetic variants associated with abnormal insulin production, increasing the risk of developing diabetes. The study's exome array genotyping analysis revealed the involvement of genes TBC1D30, KANK1, and PAM in insulin processing and secretion.
Researchers found that combining insulin and an EGF inhibitor preserved vascular integrity in diabetic mice, limiting vision damage from diabetic macular edema. The study suggests a potential therapeutic combination to prevent DME in people with diabetes.
Researchers develop method to reprogram T-cells involved in autoimmune diseases by attaching pancreatic protein to red blood cells, eliminating symptoms of type I diabetes in mice. The approach aims to minimize risks and side effects while targeting specific immune cells involved in the disease.
Researchers discovered that paroxetine protects endothelial cells from damage caused by high sugar levels in diabetes, preventing hyperglycemia-initiated reactive oxygen species damage. The drug also restores blood vessel function in animals with diabetes, suggesting potential as a new therapy for diabetic complications.
A large study finds that post-menopausal breast cancer survivors are more likely to develop diabetes, with a significant association observed after chemotherapy. The risk increases over time, suggesting the need for closer monitoring and screening of these patients.
University of Notre Dame biochemist Anthony S. Serianni's research provides new perspectives on sugar breakdown in the human body, particularly for diabetic patients. The study discovered an unexpected reaction pathway involving a novel rearrangement of the carbon backbone, undermining prevailing assumptions about sugar degradation.
Researchers found that primary care physicians provide higher quality care to diabetes patients by altering medications and offering lifestyle counseling more frequently. This study highlights the importance of a consistent primary care physician in managing chronic conditions like diabetes.
A new clinical study from Stanford University School of Medicine and Palo Alto Medical Foundation Research Institute found that pre-diabetic patients respond to self-directed lifestyle interventions, such as a take-home DVD, with similar effectiveness to coach-led programs. The study offers a practical way for primary care physicians t...
Researchers performed brown fat transplants in mice to treat obesity, finding significant reductions in body weight and improvements in glucose metabolism. The transplanted brown fat secreted hormones that mediated metabolic effects throughout the body.
A new study by RAND Corporation reveals that recent Mexican immigrants to the US have a significant amount of undiagnosed disease, including diabetes and high blood pressure. Despite this, they are still generally healthier than native-born residents after accounting for undiagnosed disease.
Researchers at Karolinska Institutet have discovered that glucagon stimulates its own synthesis, activating a self-reinforcing cycle of hormone production. This finding has significant implications for understanding the regulation of hormone secretion and may hold the key to studying defects in diabetes.
A new study published in The American Journal of Pathology found that topical application of simvastatin significantly accelerates wound healing in diabetic mice by increasing angiogenesis and lymphangiogenesis. This is attributed to the increased number of infiltrating macrophages producing VEGF-C, suggesting a simple strategy with po...
A new process of creating islet cell clusters has been successfully developed to improve pancreatic transplantation. The clusters were engineered to overcome challenges such as hypoxic conditions and immune reactions, resulting in higher viability rates and potential cure for type I diabetes.
The Decker School of Nursing at Binghamton University has received a $757,000 grant from the US Department of Health and Human Services to provide financial support for graduate students. Funded students receive tuition waivers and stipends, enabling them to focus on their studies without financial burden.
A study of 292 Brazilian women aged 45-72 found that daily step count is a strong predictor of health outcomes, with active women less likely to be obese or develop metabolic syndrome. The study supports the importance of incorporating physical activity into daily life for midlife women's overall health.
Researchers created a culturally relevant guidebook to improve Hispanic health and behaviors, focusing on physical activity and nutrition. The guidebook was well-received by community residents and addressed the Latino Paradox, highlighting the shift in healthy eating habits when immigrants arrive in the US.
A new study found that baby boomers' interest in health issues peaks in the early 50s and again near age 65. Health professionals are encouraged to target this generation with health messages at these times, as they are most receptive to hearing them.
A new study found that diabetic patients have a higher risk of hearing impairment, which is independent of aging or environmental factors. The study's findings suggest that diabetic patients should be screened for hearing impairment at an earlier age to prevent related health problems.
A new set of policy considerations was released by the Alliance to Reduce Disparities in Diabetes to address systemic barriers and structural barriers that hinder effective diabetes care. The document proposes concepts to realign financial incentives, enhance patient self-management, and optimize healthcare systems.
Researchers found that limiting carbohydrates to dinner reduced hunger scores, improved anthropometric outcomes, and lowered inflammatory markers in obese individuals. The innovative dietary pattern led to changes in hormonal secretion patterns favoring satiety and reducing metabolic risks.
Researchers found that children need at least seven minutes a day of intense physical activity to prevent weight gain and obesity. The study tracked over 600 kids aged 9-17 and showed that vigorous activity reduced the risk of unhealthy weight, while sedentary behavior was common.
A recent study published in The New England Journal of Medicine found that cardiac bypass surgery is superior to percutaneous coronary intervention (PCI) for adults with diabetes and multi-vessel coronary heart disease. After five years, the CABG group had fewer adverse events and better survival rates than the PCI group.
Recent studies suggest that hypertension and diabetes are more prevalent in black versus white donors, but the risk attributable to donation remains unknown. Individuals with prediabetes can safely donate kidneys without increasing their risk of developing diabetes or kidney failure.
The UMSOM dean and co-author argue that changes to diagnostic criteria could dramatically increase the number of women identified with gestational diabetes, placing a burden on healthcare systems. They advise caution before revising guidelines due to potential risks and costs.
A Mayo Clinic study found that a gene linked to Alzheimer's, heart disease, and diabetes becomes less important to quality of life once people reach their 90s. Researchers discovered that good friends, a positive attitude, and social connectedness have a bigger impact on well-being than the gene in question.
Research highlights the potential impact of airport security scanners on diabetes devices, including insulin pumps and continuous glucose monitoring systems. The Editorial calls for more research to understand and potentially repair this issue affecting hundreds of thousands of people worldwide who use insulin pump therapy.
A University of Illinois study found that consuming foods with advanced glycation end products (AGEs) can increase cardiovascular complications in people with diabetes. Foods like grilled meats and crispy fried foods contain AGEs, which are associated with plaque formation and heart disease.
Diabetic patients with gastroparesis can benefit from chronic electrical stimulation at specific acupuncture points, improving symptoms such as nausea and vomiting. The treatment is home-based, non-invasive, and has low side effects.
Bariatric surgery radically reduces risk factors for heart disease and stroke, with an average reduction of excess weight by 54%. Cardiovascular risks such as high blood pressure, diabetes, and unfavourable blood fats improve or resolve completely after the procedure.
A Johns Hopkins analysis found that three in 10 kidney transplant recipients require hospital readmission within 30 days. The study highlights the need for better outpatient management systems to prevent costly and potentially preventable return visits.
A systematic review and meta-analysis of 27 studies found a strong correlation between psoriasis and an increased risk of developing diabetes. Patients with severe psoriasis are nearly twice as likely to have diabetes compared to the general population.
A study combining 18 research studies found that sitting for extended periods doubles the risk of developing diabetes, heart disease and mortality. Even those meeting physical activity guidelines may still be compromised if they spend too much time sitting.