Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
A new study by University of Iowa researchers found that staph bacteria superantigens trigger pro-inflammatory molecules in fat cells, amplifying inflammation and potentially leading to diabetes. Chronic exposure to these toxins creates a 'perfect storm' for inflammation, worsening the risk of developing diabetes.
Researchers from Albert Einstein College of Medicine are leading panels on various aspects of geroscience at the NIH symposium. The event aims to understand the biological processes underlying aging and its impact on chronic diseases such as cancer, cardiovascular disease, and diabetes.
Researchers found a fat recycling system within pancreatic beta cells that regulates insulin production, providing a promising target for future diabetes treatments. By preventing this system from breaking down unwanted fats, scientists were able to increase insulin secretion.
Researchers found that diabetic mice showed reduced reactive oxygen species production in their kidneys, linked to lower AMPK activity. This decrease was associated with lowered kidney damage and improved symptoms.
A study led by Dr. Pasinetti found that diabetes alters gene expression in the brain, reducing important molecules critical for learning and memory. This epigenetic change increases the risk of developing Alzheimer's disease.
A new study found that people with lower blood sugar levels performed better on memory tests, even within the normal range. Higher blood sugar levels were associated with smaller brain volumes and poor memory performance.
A Yale School of Medicine study found that immune sensor Nlrp3 inflammasome triggers age-related inflammation, leading to loss of function and frailty. Reducing Nlrp3 activation may help delay or prevent chronic diseases.
A study at a Hamilton subsidized housing complex found that paramedics' regular visits resulted in a 32% reduction in EMS calls. The program, which included healthy lifestyle reviews and risk assessments, was well-attended by residents, with many referrals made to community resources.
A study found that combining high-intensity interval training with Mediterranean diet counselling significantly improves body fat mass, cholesterol levels, blood pressure, and weight loss in obese individuals. The intervention also resulted in improved aerobic fitness, reduced waist circumference, and better control of blood sugar levels.
A study found that high blood pressure during pregnancy may increase a woman's lifetime risk of stroke by as much as 40 percent. Women with pre-eclampsia, a more severe form of high blood pressure, are at even higher risk. Monitoring blood pressure after pregnancy is crucial to avoid longer-term risks.
A study found that stroke patients who participated in cardiac rehabilitation programs for six months showed significant improvements in walking function, with average gains of 21% in limb strength, 19% in walking speed, and 16% in walking distance. Early referral to the program was crucial for better results.
A new study reveals that body mass index (BMI) is not an effective predictor of mortality in bariatric surgery patients. Researchers found that sex, smoking status, and diabetes are better indicators of risk. The study suggests that the current practice of prioritizing bariatric surgery for obese women may be misguided, as men who are ...
A team of researchers at the University of Copenhagen has developed a new 3D method to efficiently expand pancreatic cells, allowing for the growth of miniature human pancreas models. These models can be used to test new drugs and therapies for diabetes without the need for animal models.
A new study published in Diabetologia found associations between lifestyle factors and mortality risk differ less between individuals with and without diabetes. Those with diabetes may benefit more from healthy diet but recommendations are likely to be similar
Researchers identified 13 metabolites that are significantly different in patients with diabetes and chronic kidney disease compared to healthy controls. Twelve of the metabolites are linked to mitochondrial function, suggesting suppressed mitochondria as a fundamental characteristic of diabetic kidney disease.
Researchers identified the subunit where binding took place and showed that a known activator fully activates AMPK through biochemical communication with other subunits. This discovery confirms the activation site and enables the modeling of potential drugs.
A TGen-led study has identified genetic loci associated with total bilirubin levels, steatosis, and mild fibrosis in nonalcoholic fatty liver disease. The study found evidence for new genetic factors that may help identify patients at risk of developing severe forms of fatty-liver disease.
People with poorly controlled diabetes are at risk of experiencing hypothermia, frostbite, and dehydration when traveling to high altitudes. Insulin needs may also increase or decrease due to environmental extremes, exercise, and dietary changes.
A recent study published in Nature reveals that high blood sugar levels can cause irregular heartbeats, or cardiac arrhythmia, by activating a protein called CaMKII. The researchers found that O-GlcNAc, a sugar molecule, attaches to CaMKII and causes it to become overactive, leading to pathological changes in the heart's calcium signal...
A meta-analysis found that diabetic patients have an increased risk of developing both breast and colon cancer. The study also showed that diabetic patients are at a higher risk of dying from these cancers, with a 23% increased risk for breast cancer and a 38% increased risk for colon cancer compared to non-diabetic patients.
A study found that dextrose gel treatment can almost halve the likelihood of hypoglycaemia treatment failure in at-risk babies. Babies treated with dextrose gel were less likely to be admitted to intensive care and formula fed, reducing hospital admissions and costs.
A team from IRB Barcelona discovered Mitofusin 2 plays a crucial role in measuring cellular stress levels. Removing Mfn2 leads to disrupted stress response pathways, reducing the capacity of cells to overcome stress.
A study of 3044 civil servants found that chronic exposure to high interleukin-6 levels was associated with a lower likelihood of healthy aging, including impaired musculoskeletal functioning and diabetes. Maintaining low interleukin-6 levels may facilitate successful aging by reducing the risk of these age-related diseases.
Stanford researchers have identified a molecular pathway involved in diabetes development and found an approved cancer drug that can regulate it. The drug, aflibercept, works by blocking the growth of blood vessels into tumors and starving them of oxygen, which has beneficial effects on blood glucose levels.
A recent study published in The Lancet Diabetes and Endocrinology found that people with diabetes have a 30% lower risk of dying if they undergo coronary artery bypass surgery (CABG) rather than angioplasty and inserting a stent (PCI). This significant finding has public health implications due to the large difference in outcomes.
A study published in the Journal of the American Medical Association found that electronic health records were associated with a decrease in emergency room visits and hospitalizations for patients with diabetes. The use of EHRs improved the quality of care, resulting in fewer negative events.
A study found that using electronic health records (EHRs) for patients with diabetes resulted in a modest reduction in emergency department visits and hospitalizations. However, EHR implementation did not affect office visit rates.
A new study published in Radiology found that whole-body MRI can accurately predict the risk of heart attack and stroke in diabetic patients. The study revealed that patients with detectable vascular changes on whole-body MRI faced a cumulative risk rate of 20% at three years, increasing to 35% at six years.
A study of 98,658 Chinese adults found nearly 12% had diabetes and 50% were at risk for prediabetes. The prevalence varied by age, sex, urban vs. rural residence, and economic development.
A recent study at Le Bonheur Children's Hospital found that Pedi-Flite improved outcomes for pediatric diabetic patients, reducing the need for hospital admissions. The system also saved over $760,000 by avoiding 439 ED visits and 115 admissions.
The study found that diabetic patients who received reperfusion therapy and secondary prevention medications had a lower ischemic stroke rate over time. Despite this improvement, diabetic patients were less likely to receive these treatments compared to non-diabetic patients.
A University of Maryland research team identified a cell signaling pathway that contributes to developmental defects in babies of women with diabetes. The study suggests that reducing ASK1 activity may prevent these defects and proposes the use of a naturally occurring antioxidant, thioredoxin, as a potential therapeutic target.
A recent study found that intensive lifestyle changes and metformin treatment reduced cholesterol levels and improved triglyceride profiles, lowering the risk of heart disease. The Diabetes Prevention Program analyzed over 1,600 participants, showing positive changes in blood particle distribution.
A recent study found a strong association between gestational diabetes and sleep apnea in pregnant women. Women with gestational diabetes lost an hour of sleep each night, increasing their risk for stroke, cardiovascular disease and heart attacks.
A new study from the University of Michigan researchers found that children with higher BPA levels had a higher odds of obesity and adverse levels of body fat. The study measured BPA levels in children's urine and found an association between high BPA levels and abnormal waist circumference-to-height ratio.
A study of over 2,000 patients aged 65+ found a strong association between higher blood sugar levels and increased dementia risk. Higher glucose levels were linked to a 40% increased risk in people with diabetes.
A new study published in the American Journal of Preventive Medicine found that walking to work cuts the risk of diabetes and high blood pressure by 40% compared to driving. People who walk or cycle to work are also less likely to be overweight, with cyclists being half as likely to have diabetes as drivers.
Contemplating reasons for seeking or avoiding health information increases willingness to follow up with the doctor, particularly for treatable conditions. This effect was found in two studies investigating participants' motivations and risk calculators.
Talking on a cellphone while driving raises the risk of collision by four to six times. Physicians can educate patients through open dialogue about the hazards of talking while behind the wheel, and offer advice such as turning off cellphones or pulling over to make important calls.
A new study published in the journal Stroke found that regularly exercising to break a sweat lowers stroke risk. The study of over 27,000 participants showed that those who exercised four or more times a week had a 20% lower risk of stroke compared to those who were inactive.
A new study reveals that nearly half of Mexican American children aged 6-17 show signs of metabolic syndrome, a cluster of warning signs for diabetes and heart disease. Early screening is critical to identify risk factors and intervene before chronic health problems develop.
Israel's unique blend of medical innovation, universal accessibility and patient compliance leads to significant reduction in preventable blindness rates. The country's success in preventing avoidable blindness has emerged as a world leader, making it an attractive model for other nations.
The University of Illinois Chicago will lead a $15.3 million NIH project to follow up with all Chicago participants in the Hispanic Community Health Study/Study of Latinos, a large-scale study of Hispanic/Latino health. The study aims to investigate chronic diseases and risk factors in this population.
A new study conducted by Indiana University found that postmenopausal women who quit smoking reduced their risk of heart disease, with benefits starting to show within years. The study analyzed data from 104,391 women ages 50-79 and found a significant drop in heart disease risk among those who quit smoking, regardless of diabetes status.
Researchers found that smoking cessation lowered the risk of coronary heart disease among postmenopausal women with and without diabetes. However, weight gain after quitting weakened this association, particularly for women who gained 11 lbs or more, according to a study using data from the Women's Health Initiative.
A study found that pregnant women with pre-pregnancy diabetes are more than three times as likely to become infected with MRSA before hospital discharge. Researchers also found no association between gestational diabetes and MRSA infection.
A scientist is working to bolster the body's natural antioxidant system to interrupt a vicious cycle of inflammation and free radicals that cause vision loss in diabetes. The goal is to use a selenium supplement to improve the thioredoxin system, which helps neutralize excess free radicals.
Diabetes-related mortality in UK and Canada has declined significantly since the mid-1990s, with a narrowing of the gap in mortality risk between those with and without diabetes. The excess risk of mortality for diabetic patients decreased over time, with notable reductions in all age groups.
Studies explore the benefits of behavioral interventions for managing diabetes, as well as the impact of insulin pump therapy and fetal outcomes in diabetic women. Researchers from Montefiore Medical Center and Albert Einstein College of Medicine present their findings on these topics at the American Diabetes Association meeting.
A study found that low-income uninsured adults are less likely to have chronic conditions like hypertension, diabetes, and hypercholesterolemia. However, those with these conditions are more likely to be undiagnosed or uncontrolled.
A new study from MIT reveals that a gene called SIRT1, previously shown to protect against diseases of aging, plays a key role in controlling circadian rhythms. The researchers found that boosting SIRT1 levels in the brain could prevent age-related decline in circadian function and potentially lead to health benefits.
Researchers found significant declines in diabetes-related mortality in the UK and Canada since the mid-1990s. The excess risk of mortality for diabetic patients decreased by 25%-40% across all age groups, with the greatest reductions seen among younger individuals.
Dr. Graeme Bell has been awarded the 2013 Banting Medal for his pioneering work in understanding the role of genetics in diagnosing and treating diabetes. His research focuses on the biology of insulin-secreting pancreatic beta-cells and the use of genetics to personalize treatment.
A study found that combining metformin and liraglutide results in greater weight loss and improvements in body mass index and waist circumference for women with polycystic ovary syndrome. This combination therapy also leads to higher chances of conception, improved pregnancy outcomes and improved metabolic profile.
A recent study found that postmenopausal women who experience depression or take antidepressant medication have a higher risk of developing diabetes and cardiovascular disease. The study, led by Dr. Yunsheng Ma, found associations between elevated depressive symptoms, increased insulin levels, and higher waist circumference.
A nanofiber sensor developed by researchers at KAIST can detect acetone levels associated with diabetes and toluene levels linked to lung cancer. The sensor offers a highly sensitive detection of these biomarkers, which is important for accurate diagnosis.
People in India who walk or cycle to work are less likely to be overweight or obese, have diabetes or high blood pressure. The study found similar patterns for rates of high blood pressure and diabetes, highlighting the importance of active modes of transport.
Researchers at the University of Pittsburgh have developed a sensor technology that can detect and monitor diabetes through breath analysis alone. The sensor uses a combination of titanium dioxide and carbon nanotubes to measure acetone vapors in breath, offering a potential alternative to current blood glucose monitoring methods.
The US Preventive Services Task Force found primary care interventions for preventing child maltreatment to be ineffective due to limited evidence. In contrast, diabetes patients on Medicare are two to three times more likely to use brand-name drugs than VA patients, at an added annual cost of $1 billion.
Researchers found hospitalization for severe hypoglycemia doubled dementia risk, while dementia patients experienced twice as likely severe hypoglycemic events. Cognitive impairment may lead to poor diabetes management and worse health.