Articles tagged with Diabetes
Studies examine how depleted food budgets can increase risk of hypoglycemia among low-income individuals with diabetes. Additionally, researchers find that workers with diabetes are more likely to retire earlier in countries worldwide.
Researchers have found that fructosamine and glycated albumin are strongly associated with retinopathy and kidney disease in patients with diabetes. These tests could potentially replace the standard Hemoglobin A1c test, which is not valid for some patients.
Panel members of the Institute of Medicine's Eighth Joint National Committee opposed relaxing systolic blood pressure targets to 150 mmHg, citing insufficient evidence. The decision may reduce antihypertensive treatment intensity, potentially reversing declines in cardiovascular disease mortality rates.
A study by researchers at the Medical College of Georgia has identified two players that must work together to destroy vision in patients with diabetes. The findings suggest that blocking the production of reactive oxygen species by either retinal cells or white blood cells may be a viable strategy for intervention.
Research by the University of Exeter Medical School reveals two new genetic causes of neonatal diabetes, providing insights into how insulin-producing beta cells are formed in the pancreas. This discovery increases the number of known genetic causes of neonatal diabetes, offering hope for improved treatment and potential therapies.
Elevated tyrosine levels in obese individuals are linked to a higher risk of developing diabetes. Researchers propose that tyrosine may directly affect insulin signaling, leading to increased blood sugar levels.
Researchers found that patients with congenital arrhythmia produce twice the amount of insulin after consuming sugar, leading to drastically low blood sugar levels. The discovery could have significant implications for treatment of diabetes and management of hypoglycaemia.
Researchers have made a breakthrough in packaging insulin into tiny sacs that can be absorbed through the gut, overcoming digestive enzyme hurdles. The new delivery system has shown promising results in rats, with blood glucose levels lowered almost as much as injected insulin.
The new guideline provides evidence-based recommendations for treating high blood pressure in adults, with a focus on reducing disease burden and improving health outcomes. The report recommends specific treatment thresholds and medication choices based on age, diabetes status, and kidney function.
A new study by Uppsala University reveals a strong association between high levels of perfluorinated compounds and the development of diabetes. High levels of perfluorononanoic acid (PFNA) and perfluorooctanoic acid (PFOA) were found to be linked to increased diabetes risk in elderly men and women.
Researchers found that HCV antiviral therapy reduces risks of kidney disease, stroke, and cardiovascular diseases in diabetic patients. The study also linked diabetes with chronic HCV infection, suggesting a potential association between the two conditions.
A new study has found a significant association between diabetes and an increased risk of developing hepatocellular carcinoma, also known as liver cancer, in various ethnic groups. The study revealed that people with diabetes have a two- to threefold higher risk for liver cancer compared to those without the condition.
A newly discovered human peptide called humanin may become a new treatment for diabetes by increasing insulin secretion and improving glucose metabolism in beta cells. Humanin levels naturally decline with age, suggesting potential benefits for patients with other conditions like stroke, heart disease, and Alzheimer's.
Research suggests that age-adjusted rates of dementia have declined for people born later, particularly those at higher risk. Lifestyle factors such as exercise and diet are being studied as potential contributors to this trend.
A Kaiser Permanente study of 17,217 adult members with diabetes found that those using mail order pharmacies had significantly fewer emergency room visits for any cause. The study suggests that mail order pharmacy may improve patient safety and utilization without compromising patient outcomes.
A recent study published in Stem Cells has identified brown fat stem cells in adult humans, which may lead to new treatments for heart and endocrine disorders. The discovery could help increase the body's own ability to make brown fat or find novel ways to directly implant the cells into patients.
Research found that obese people who are metabolically healthy still face an increased risk of developing diabetes and cardiovascular disease. The study analyzed data from over 5,700 participants and found that normal weight individuals with multiple metabolic abnormalities also faced a higher risk of cardiovascular disease.
A study found that younger Hispanic and black women have a higher risk of in-hospital death after a heart attack compared to white men. Additionally, they are more likely to suffer from diabetes and have limited access to treatment options such as percutaneous coronary interventions or coronary artery bypass surgery.
Swedish researchers have found a way to study glucose regulation by transplanting pancreas cells into the eye, allowing for monitoring of insulin-producing beta-cells and identification of new drug substances. This innovative method could lead to personalized treatment principles and diagnosis of pancreatic problems.
Researchers identified key factors facilitating or hindering the adoption of shared medical appointments (SMAs) in three physician offices. Successful SMA implementation requires careful planning and effective communication among healthcare providers.
A study published in Annals of Emergency Medicine found that diabetic patients treated in the emergency department who received automated daily text messages improved their blood glucose levels and self-reported medication adherence. The program reduced the need for emergency department visits and was well-received by participants.
African Americans with APOL1 gene variant experience faster chronic kidney disease progression and increased risk of kidney failure compared to those without the variant. The study found that APOL1 risk variants increase CKD progression in African Americans, regardless of their diabetes status.
African-American patients with chronic kidney disease have a faster decline in kidney function due to genetic variations, particularly the APOL1 gene variant. The study suggests that reducing the effect of this gene could lead to a significant decrease in progressive kidney and end-stage kidney disease in blacks.
Researchers at UTMB have discovered that PKC activation leads to alternative splicing events in the heart, causing developmental shift and preventing correct functioning. This finding could help lead to prevention and treatment of heart failure in diabetics.
Researchers at UCSF advocate empowering all team members to care for a large number of patients based on their training and abilities. They recommend expanding the scope of practice for registered nurses, pharmacists, physical therapists, and medical assistants to provide care for uncomplicated medical problems.
Three years after bariatric surgery, patients experienced significant weight loss, particularly in the first year. The study found that while there was variability in weight loss outcomes, many patients achieved substantial improvements in diabetes, blood pressure, and lipid profiles.
Severely obese patients who underwent gastric bypass or laparoscopic adjustable gastric banding surgical procedures experienced substantial weight loss, with most of the change occurring in the first year. The study also found significant improvements in obesity-related complications, including diabetes, hypertension, and high choleste...
A recent study of diabetic patients who underwent revascularization for multi-vessel coronary artery disease found that insulin-treated patients experienced higher rates of major adverse cardiovascular events, including death, stroke, and myocardial infarction. CABG was found to reduce mortality and myocardial infarction rates compared...
A new study by University of Iowa researchers found that staph bacteria superantigens trigger pro-inflammatory molecules in fat cells, amplifying inflammation and potentially leading to diabetes. Chronic exposure to these toxins creates a 'perfect storm' for inflammation, worsening the risk of developing diabetes.
Researchers from Albert Einstein College of Medicine are leading panels on various aspects of geroscience at the NIH symposium. The event aims to understand the biological processes underlying aging and its impact on chronic diseases such as cancer, cardiovascular disease, and diabetes.
Researchers found a fat recycling system within pancreatic beta cells that regulates insulin production, providing a promising target for future diabetes treatments. By preventing this system from breaking down unwanted fats, scientists were able to increase insulin secretion.
Researchers found that diabetic mice showed reduced reactive oxygen species production in their kidneys, linked to lower AMPK activity. This decrease was associated with lowered kidney damage and improved symptoms.
A study led by Dr. Pasinetti found that diabetes alters gene expression in the brain, reducing important molecules critical for learning and memory. This epigenetic change increases the risk of developing Alzheimer's disease.
A new study found that people with lower blood sugar levels performed better on memory tests, even within the normal range. Higher blood sugar levels were associated with smaller brain volumes and poor memory performance.
A Yale School of Medicine study found that immune sensor Nlrp3 inflammasome triggers age-related inflammation, leading to loss of function and frailty. Reducing Nlrp3 activation may help delay or prevent chronic diseases.
A study at a Hamilton subsidized housing complex found that paramedics' regular visits resulted in a 32% reduction in EMS calls. The program, which included healthy lifestyle reviews and risk assessments, was well-attended by residents, with many referrals made to community resources.
A study found that combining high-intensity interval training with Mediterranean diet counselling significantly improves body fat mass, cholesterol levels, blood pressure, and weight loss in obese individuals. The intervention also resulted in improved aerobic fitness, reduced waist circumference, and better control of blood sugar levels.
A study found that high blood pressure during pregnancy may increase a woman's lifetime risk of stroke by as much as 40 percent. Women with pre-eclampsia, a more severe form of high blood pressure, are at even higher risk. Monitoring blood pressure after pregnancy is crucial to avoid longer-term risks.
A study found that stroke patients who participated in cardiac rehabilitation programs for six months showed significant improvements in walking function, with average gains of 21% in limb strength, 19% in walking speed, and 16% in walking distance. Early referral to the program was crucial for better results.
A new study reveals that body mass index (BMI) is not an effective predictor of mortality in bariatric surgery patients. Researchers found that sex, smoking status, and diabetes are better indicators of risk. The study suggests that the current practice of prioritizing bariatric surgery for obese women may be misguided, as men who are ...
A team of researchers at the University of Copenhagen has developed a new 3D method to efficiently expand pancreatic cells, allowing for the growth of miniature human pancreas models. These models can be used to test new drugs and therapies for diabetes without the need for animal models.
A new study published in Diabetologia found associations between lifestyle factors and mortality risk differ less between individuals with and without diabetes. Those with diabetes may benefit more from healthy diet but recommendations are likely to be similar
Researchers identified 13 metabolites that are significantly different in patients with diabetes and chronic kidney disease compared to healthy controls. Twelve of the metabolites are linked to mitochondrial function, suggesting suppressed mitochondria as a fundamental characteristic of diabetic kidney disease.
Researchers identified the subunit where binding took place and showed that a known activator fully activates AMPK through biochemical communication with other subunits. This discovery confirms the activation site and enables the modeling of potential drugs.
A TGen-led study has identified genetic loci associated with total bilirubin levels, steatosis, and mild fibrosis in nonalcoholic fatty liver disease. The study found evidence for new genetic factors that may help identify patients at risk of developing severe forms of fatty-liver disease.
People with poorly controlled diabetes are at risk of experiencing hypothermia, frostbite, and dehydration when traveling to high altitudes. Insulin needs may also increase or decrease due to environmental extremes, exercise, and dietary changes.
A recent study published in Nature reveals that high blood sugar levels can cause irregular heartbeats, or cardiac arrhythmia, by activating a protein called CaMKII. The researchers found that O-GlcNAc, a sugar molecule, attaches to CaMKII and causes it to become overactive, leading to pathological changes in the heart's calcium signal...
A meta-analysis found that diabetic patients have an increased risk of developing both breast and colon cancer. The study also showed that diabetic patients are at a higher risk of dying from these cancers, with a 23% increased risk for breast cancer and a 38% increased risk for colon cancer compared to non-diabetic patients.
A study found that dextrose gel treatment can almost halve the likelihood of hypoglycaemia treatment failure in at-risk babies. Babies treated with dextrose gel were less likely to be admitted to intensive care and formula fed, reducing hospital admissions and costs.
A team from IRB Barcelona discovered Mitofusin 2 plays a crucial role in measuring cellular stress levels. Removing Mfn2 leads to disrupted stress response pathways, reducing the capacity of cells to overcome stress.
A study of 3044 civil servants found that chronic exposure to high interleukin-6 levels was associated with a lower likelihood of healthy aging, including impaired musculoskeletal functioning and diabetes. Maintaining low interleukin-6 levels may facilitate successful aging by reducing the risk of these age-related diseases.
Stanford researchers have identified a molecular pathway involved in diabetes development and found an approved cancer drug that can regulate it. The drug, aflibercept, works by blocking the growth of blood vessels into tumors and starving them of oxygen, which has beneficial effects on blood glucose levels.
A recent study published in The Lancet Diabetes and Endocrinology found that people with diabetes have a 30% lower risk of dying if they undergo coronary artery bypass surgery (CABG) rather than angioplasty and inserting a stent (PCI). This significant finding has public health implications due to the large difference in outcomes.
A study published in the Journal of the American Medical Association found that electronic health records were associated with a decrease in emergency room visits and hospitalizations for patients with diabetes. The use of EHRs improved the quality of care, resulting in fewer negative events.
A study found that using electronic health records (EHRs) for patients with diabetes resulted in a modest reduction in emergency department visits and hospitalizations. However, EHR implementation did not affect office visit rates.
A new study published in Radiology found that whole-body MRI can accurately predict the risk of heart attack and stroke in diabetic patients. The study revealed that patients with detectable vascular changes on whole-body MRI faced a cumulative risk rate of 20% at three years, increasing to 35% at six years.
A recent study at Le Bonheur Children's Hospital found that Pedi-Flite improved outcomes for pediatric diabetic patients, reducing the need for hospital admissions. The system also saved over $760,000 by avoiding 439 ED visits and 115 admissions.
A study of 98,658 Chinese adults found nearly 12% had diabetes and 50% were at risk for prediabetes. The prevalence varied by age, sex, urban vs. rural residence, and economic development.
The study found that diabetic patients who received reperfusion therapy and secondary prevention medications had a lower ischemic stroke rate over time. Despite this improvement, diabetic patients were less likely to receive these treatments compared to non-diabetic patients.
A University of Maryland research team identified a cell signaling pathway that contributes to developmental defects in babies of women with diabetes. The study suggests that reducing ASK1 activity may prevent these defects and proposes the use of a naturally occurring antioxidant, thioredoxin, as a potential therapeutic target.