Articles tagged with Lesions
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Researchers expand the ABCD rule to recognize changing characteristics of early melanomas, especially nodular melanomas. The new guideline aims to improve detection and diagnosis of this aggressive form of skin cancer.
A new magnetic-assisted intervention system has shown a high success rate in navigating tortuous coronary arteries, making it easier to treat patients with difficult lesions. The system, developed by Stereotaxis, Inc., uses two permanent magnets to generate a magnetic field and guide wires through the heart.
A US study found that most low-grade cervical lesions (LSIL) in young women will regress spontaneously, lending support for monitoring these cytological lesions. Follow-up HPV status was a strong predictor of regression, but persistent multiple HPV types slowed rates of regression.
A recent study published in the American Journal of Roentgenology found that virtual colonoscopy is equally effective for detecting both flat and non-flat types of lesions. The study detected 80% of flat lesions and 81% of non-flat lesions, with no diminutive flat lesions showing histological advanced lesions.
Researchers found that the temporoammonic (TA) projection is crucial for the dialog between the hippocampus and cortex after learning, suggesting a window of vulnerability for memory consolidation. The study opens up new avenues for exploring the role of sleep in memory formation.
Researchers found that combining 308-nm excimer laser therapy with topical tacrolimus ointment resulted in 100% repigmentation in group A lesions and 85% in group B. The treatment was well tolerated, with an average of 10-12 sessions needed to see improvement.
Optical colonoscopy may miss between 10-14% of polyps, highlighting the need for virtual colonoscopy. Meanwhile, a study on West Nile fever reveals more serious symptoms and longer recovery times than previously thought. Resynchronization of heart function after a heart attack can improve quality of life but is not cost-effective.
Immune cells that get trapped in atherosclerotic plaques attract more immune cells, setting up a cycle that leads to continued progression of the disease. Monocytes take up permanent residence in plaques due to altered differentiation factors.
Researchers have identified a potential molecular target to halt the spread of human papillomavirus (HPV), a common cause of cervical cancer. By targeting specific RNA molecules that produce proteins driving cellular proliferation, HPV-infected cells may be eradicated, offering new treatment options.
Researchers tested angiostatic therapy on mice with endometriosis lesions, finding it inhibited new blood vessel growth and reduced existing lesion size. The most effective compound was endostatin, which also showed no side effects in animal trials.
A recent study using diffusion weighted imaging found small brain lesions appearing on MRI scans of amnesiac patients within hours and days of onset. The lesions were all located in the hippocampus, a key area for memory functions, suggesting a possible cause for transient global amnesia.
Researchers use 18F-FDDNP-PET to measure tangles and plaques in brain, providing valuable information on disease status. The technique accurately separates AD patients from control subjects, offering opportunities for early diagnosis and monitoring treatment effects.
Research suggests that telomere dysfunction may be a key component in the development of many epithelial cancers. Telomere length abnormalities were observed in 97% of precancerous lesions, with abnormally short telomeres found in 88%.
A new study found that MRI is more effective than PET in detecting small liver metastases, with an accuracy rate of 75.5%, compared to PET's 64.1%. The study used a custom liver-specific contrast agent, which improved image resolution and detection of smaller lesions.
A study found that women with core breast biopsy results showing minimal abnormal cells were still at risk of having cancer when surgical excision was performed. The study suggests that these women should undergo surgical excision to ensure accurate cancer detection.
A new CAD system has shown promise as an adjunct to breast MRI in identifying benign lesions. The study found that the CAD system could help reduce biopsy rates by 18% if proven effective in larger studies.
Researchers found that a blood pressure-lowering regimen in stroke patients can stop or delay further ischemic brain damage. The study showed that patients who received the medication had significantly fewer new white matter lesions compared to those who took placebo.
A study published in JAMA found that computed tomographic colonography (CTC) had lower sensitivity rates compared to conventional colonoscopy for detecting colorectal tumors, raising concerns about its readiness for widespread clinical use.
Researchers found that a new MVA vaccine was effective in protecting monkeys from both smallpox and monkeypox. The vaccine elicited similar immune responses as the current Dryvax vaccine, with all immunized animals surviving a lethal monkeypox infection and showing no clinical signs of disease.
A new vaccine has been shown to halt HER-2/neu preneoplastic breast cancer lesions through both morphologic and gene expression data. The findings suggest a potential breakthrough in the treatment of this type of cancer, according to a recent study published in JCI Journals.
A new study found that moderate alcohol intake may promote brain atrophy, which can lead to lower cognition and reduced extremity function. The research, published by the American Heart Association, used magnetic resonance imaging (MRI) to assess brain abnormalities in middle-aged adults.
A new study at Dana-Farber Cancer Institute finds that surgery alone is not sufficient to treat DCIS, a common type of breast lesion. Recurrence rates were higher than expected, with 13 patients experiencing repeated DCIS lesions and four diagnosed with invasive breast cancer.
A study of 1,036 women with ductal carcinoma in situ (DCIS) diagnosed at age 40 or older found that those with high-nuclear-grade lesions had a higher risk of invasive cancer recurrence. Women treated by lumpectomy alone who experienced initial palpation-detected lesions also faced a greater risk of recurrence.
A new treatment using 15% azelaic acid gel has been shown to be more effective than metronidazole gel in reducing rosacea symptoms. Patients who used the azelaic acid gel experienced a greater reduction in redness and lesion count compared to those who used metronidazole gel.
A study published in BRAIN found that frontal lobe damage can lead to inconsistent performance, even on simple tasks, with effects varying across brain regions. The researchers identified specific areas of the frontal lobes responsible for increased variability, shedding light on the mechanisms underlying this phenomenon.
A study found that chronic alcoholism can cause damage to both the prefrontal cortex and cerebellum, leading to deficits in executive functioning and balance. The research suggests that lesions in the frontocerebellar circuitry may compound their effects on these functions.
The American Academy of Neurology has introduced a new guideline that suggests MRI scans can be used to predict the development of multiple sclerosis in individuals who have had a single occurrence of MS symptoms. This allows for earlier diagnosis and treatment, which can help reduce disease activity and severity.
Researchers have created a triple-transgenic mouse that exhibits both plaque and tangle lesions, allowing them to study the relationship between the two and develop drugs targeting both. This model could lead to a single class of drugs for treating both inherited and sporadic forms of Alzheimer's disease.
Researchers found that HPV16 is less associated with immune status than other HPV types, suggesting it can skirt the immune system. This discovery raises hypotheses about why cervical cancer rates are only moderately increased in HIV/AIDS-affected women.
A new study found that repair enzymes can 'distinguish' between various positions on the DNA strand, varying in effectiveness depending on their orientation relative to the nucleosome. This discovery has significant implications for our understanding of DNA repair and its role in preventing diseases like cancer and Alzheimer's.
The study showed that FDHT-PET detected osseous lesions in patients with advanced metastatic prostate cancer, confirming its utility in evaluating prostate cancer patients. The test also revealed the presence of additional lymph node lesions not identified by CT scans, suggesting its potential to predict response to hormone therapy.
A new study suggests that the area where carcinogens settle may play a key role in developing lung cancer. The research found that cells located at carinal ridges can receive massive doses of toxic particulate matter, potentially leading to impaired mucociliary clearance and increased risk of neoplastic lesions.
A new study found that Gleevec significantly reduced Kaposi's sarcoma lesions in five HIV-positive patients, with one patient experiencing a 90% regression. The therapy targets cancer cells and eliminates debilitating side effects associated with chemotherapy.
Researchers found that 3D mammography (TOMO) outperforms traditional mammography in detecting breast lesions, including masses and architectural distortions. The technique has the potential to reduce anxiety for patients by providing a more accurate diagnosis upfront.
A new low-dose CT colonography technique reduces radiation risk for non-invasive colon cancer screening. However, it may limit subtle differentiation of extracolonic soft tissues. The study suggests that this technique is suitable for asymptomatic screening but may require a standard dose for symptomatic patients.
A new MR-guided breast biopsy method has been developed and tested on 35 patients, achieving high technical success rates. The method uses a stainless steel core biopsy needle with an MR-compatible coaxial device, allowing for accurate targeting of lesions and improved patient outcomes.
A study of 33 patients found MR imaging to be more effective than ultrasound in diagnosing large lesions and precisely localizing paratesticular lesions. The use of MR imaging as a follow-up to sonography can reduce costs and recovery time associated with unnecessary biopsies or surgical intervention.
A Wake Forest researcher has identified a syndrome that causes brain malformations, leading to death in premature infants. The malformations were found using ultrasound and MRI scans during autopsies of premature infants who died soon after birth.
Researchers studied adults whose cognitive abilities were first tested at 11 and found that brain white-matter abnormalities made a significant contribution to general cognitive ability differences in old age. Early IQ scores also played a role, but independently of each other.
A study of 664 patients with moderate papulopustular facial rosacea found that azelaic acid 15% gel significantly reduced redness and the number of inflammatory lesions. The treatment also showed promise for improving overall quality of life, with patients reporting comfort and satisfaction with the product.
A new study examines the incidence of breast cancer among postmenopausal women with 'probably benign' mammographic findings. The research suggests that short-interval follow-up may not be necessary, and a 1-year follow-up may be as effective as a 6-month follow-up in identifying early-stage breast cancers.
Researchers analyzed data from NHANES III to find that serious periodontal disease doubles the risk of pre-cancerous lesions and quadruples the risk of oral tumors. The study suggests a potential link between gum disease and oral cancer, with implications for early detection and prevention.
A study published in The Lancet found that same-day testing and treatment led to high rates of compliance with recommended treatment, with 83.2% returning for a follow-up visit. The 'one-stop' approach also improved patient satisfaction, with nearly 98% saying the treatment was equal to or better than expected.
Researchers at Beth Israel Deaconess Medical Center found that administering small doses of carbon monoxide before a 'balloon-like injury' to mouse carotid vessels reduced arteriosclerotic lesions by 60-80 percent. This suggests potential benefits for patients undergoing angioplasty or heart transplant procedures.
The new digital tomosynthesis system provides high-resolution cross-section images with reduced structure overlap, making lesions easier to detect. This technology has the potential to revolutionize breast cancer detection and diagnosis, allowing for earlier interventions.
Researchers found that active brain lesions are key predictors of seizure recurrence in patients with neurocysticercosis. The study suggests that anti-epileptic drugs should be continued until lesions are resolved, and further research on antihelminthic drug therapy is recommended.
A UC Riverside study of 2,055 brown recluse spiders in a Kansas home found no bites on occupants. The study suggests that many skin lesions misdiagnosed as 'brown recluse spider bites' are actually caused by other factors like infections or bug bites.
A Norwegian study demonstrates that COX-2 inhibitors (coxibs) can be effective in preventing oral cancer by targeting high-risk individuals. The study's results suggest that coxibs may be a promising approach to chemoprevention, particularly for head and neck cancer patients.
Researchers discovered that telomere shortening is a common feature in high-grade prostatic intraepithelial neoplasia (HGPIN), the precursor to prostate cancer. Shortened telomeres were found in 93% of HGPIN lesions, suggesting their role as potential biomarkers for early detection and prevention.
Researchers found that more frequent ivermectin treatment reduced the number of female worms responsible for the disease by one third. Higher doses or frequency did not provide additional benefits, but were associated with some visual disturbances in patients.
The new high-resolution breast-specific gamma camera has been shown to detect more breast cancers than standard gamma cameras, with a sensitivity increase of 20% in lesions <1cm. The study used 50 women with 58 lesions and found that the new scanner detected 3 additional lesions not visible on mammography.
University of Pittsburgh researchers found combined PET/CT scans to be a valuable tool for staging and re-staging patients with difficult-to-track cancers. The technology identified additional cancerous lesions in 80% of ovarian carcinoma patients and 45% of cervical carcinoma patients, leading to changes in treatment plans.
A recent study published in the Pediatric Academic Societies found that low-grade cervical lesions (LSILs) tend to clear up on their own in adolescent women. The study of 187 adolescents aged 13-22 years showed that only 4% had persistent LSILs after three years, and most regressed within three months.
Researchers analyzed seasonal changes in immune system activity among 28 MS patients, finding more activated T-cells during autumn months. However, no significant variation was detected in lesions or relapse rates, challenging previous theories on the topic.
A new ultrasound technique called Acoustic Radiation Force Impulse (ARFI) imaging can detect and characterize breast abnormalities that are deeper and smaller than previously thought. The method uses high-frequency sound pulses to 'feel' the tissues, revealing differences in stiffness and mechanical properties.
Researchers successfully implanted nerve cells in rats with partial hemisection spinal cord damage, showing partial recovery of walking abilities. In contrast, complete transection and ventral root avulsion models showed limited or no regrowth of damaged motor neurons.
A recent study suggests that users of the former Viadent formulation are eight to 11 times more likely to develop oral leukoplakia than those who have never used the product. Leukoplakia can sometimes lead to oral cancer, and patients with this condition should be alert for symptoms.
Researchers suggest a new approach to managing abnormal cervical smears, recommending a 'wait and see' period of at least 6 months for women infected with high-risk human papillomavirus. This strategy aims to prevent overtreatment by allowing the virus to clear before further action is taken.
Researchers developed a new outpatient treatment for snoring that uses radiofrequency energy to create multiple lesions in the soft palate, reducing vibrations and improving effectiveness. The study showed significant reduction in snoring and increased success rates compared to single lesion methods.
Researchers found upper airway sensory impairment in snorers and OSA patients, increasing the risk of obstructive breathing episodes. The study also showed partial reversibility of sensory changes with continuous positive airway pressure treatment.