Articles tagged with Lesions
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Researchers demonstrate feasibility and safety of magnetic-anchor-guided endoscopic submucosal dissection (MAG-ESD) for large early gastric cancer in humans. The technique facilitates en bloc removal of lesions by providing retraction capability using magnets, simplifying the procedure.
A study published in the Journal of the National Cancer Institute found that HPV18 DNA levels are not associated with the likelihood of progressing to advanced precancerous lesions of the cervix. The study suggests that testing for high levels of HPV18 DNA is not clinically useful.
A new study reveals a consistent pattern of brain injury to the frontal lobe and right hemisphere causes delusions. The overcompensation of the left hemisphere leads to the creation of false narratives that cannot be edited, resulting in pathologic beliefs.
A study published in the American Journal of Roentgenology found that MR arthrography was more accurate than conventional MRI in diagnosing shoulder tears. The procedure improved detection rates for various types of tears, including labral and supraspinatus tendon tears.
A new screening test using barium meal follow through with pneumocolon has been proposed for chronic abdominal pain of luminal origin. The test can detect both small and large bowel lesions, reducing the need for separate colonoscopy procedures.
A new computer-aided screening technique has been developed to diagnose enteric lesions in capsule endoscopy, reducing the reading time from 5 hours to 1 hour on average. The technique uses image processing to screen out normal images, allowing for accurate diagnosis with high sensitivity rates.
A Canadian study found colonoscopy is associated with lower death rates from colorectal cancer, but raises concerns about detection of lesions on the right side of the colon. Patients are urged to seek a qualified gastrointestinal endoscopist to perform a thorough colonoscopy.
A new breast imaging technology, BSGI, has been shown to detect additional lesions in women with suspicious mammography results. The study found that BSGI identified an additional suspicious lesion in 29% of women and 36% of those who underwent biopsy as cancerous.
A new statistical model, developed by researchers at the Seattle Cancer Care Alliance, uses three key characteristics to predict malignancy in breast lesions. The model identifies patients and lesions that are highly likely to be benign, allowing for reduced unnecessary biopsies.
A laparoscopic approach was used to successfully treat two cases of retrorectal cysts, a rare developmental lesion. The procedure allowed for perfect visualization of deep structures in the presacral space, minimizing surgical trauma.
A randomized trial found that indigo naturalis ointment significantly improved scaling, erythema, and induration in patients with treatment-resistant psoriasis. After 12 weeks, the treated plaques showed an 81% improvement compared to a 26% improvement for non-medicated ointment-treated lesions.
A study published by researchers in Japan found that Double Balloon Endoscopy (DBE) was effective in diagnosing small intestinal lesions in patients with obscure GI bleeding, with a sensitivity of 92.7%. DBE also showed therapeutic benefits for most patients, and the technique was more sensitive than capsule endoscopy in certain cases.
A phase II trial of oral fumarate (BG00012) showed a 69% reduction in new gadolinium enhancing lesions and a 32% decrease in annual relapse rate. Longer-term studies are underway to confirm these findings and establish its place in multiple sclerosis treatment.
A study published in The Lancet predicts John McCain's mortality rate due to melanoma, with a 10-year survival rate of 24%. The author suggests that McCain's risk improves if his cancer has not spread, reducing the annual mortality rate to 6% per year.
Phase IIb data show that BG-12 significantly reduced brain lesions in patients with relapsing-remitting multiple sclerosis, with a 53% reduction in T1-hypointense lesions. The treatment also demonstrated favorable safety and potential neuroprotective benefits.
Drinking more than moderate amounts of alcohol is associated with reduced total brain volume and larger white matter lesions. This finding suggests that heavy drinking may not have the protective effect on brain health previously thought, contrary to its effects on cardiovascular disease risk.
Three new devices are being showcased to reduce blockages in peripheral and coronary arteries, providing cardiac support. The AngioSculpt device optimizes stenting of complex lesions with a low rate of complications.
Research studies and clinical registry data suggest that triple antiplatelet therapy achieves greater platelet inhibition than conventional dual antiplatelet therapy in patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stents. This leads to reduced early mortality and major adverse cardiac events without in...
Two studies presented at the American College of Gastroenterology's Annual Scientific Meeting highlight new technologies that improve the detection of colorectal polyps and flat lesions. The Retroscope device was found to significantly increase polyp detection, while narrow band imaging improved detection of flat or depressed lesions.
Researchers found that women who smoked fewer pack years had a higher risk of developing significant colorectal neoplasia. Smoking also increased the risk of pancreatic cancer precursor lesions in at-risk patients with a family history of pancreatic cancer.
A new study found that severe esophageal damage is rare in asymptomatic children after caustic ingestion. The study concluded that an endoscopy should be performed in all symptomatic patients to predict esophageal lesions and prevent complications.
The study found that rebamipide enema therapy significantly reduced mean fasting period and duration of hospitalization compared to conventional therapy. The degree of ulcer healing also showed a favorable trend, although not statistically significant.
Researchers found that HPV testing with P16INK4A expression increases sensitivity for detecting high-grade precancerous cervical lesions compared to conventional cytology. This improvement comes without increasing referral to colposcopy. The study suggests using triage by P16INK4A immunostaining in HPV-positive women.
Merging multiple CT images simplifies probe repositioning during radiofrequency ablation treatments, according to a recent study. The summation method allows for rapid and accurate visualization of treated areas, increasing the effectiveness of the treatment.
The LEADERS study demonstrated that Biosensors DES is non-inferior to Cypher DES in terms of clinical events, stent thrombosis rates and angiographic follow-up data. The trial included a broad range of patients with symptomatic coronary disease, reflecting routine clinical practice.
A new MRI contrast medium, Gadofluorine M, has been developed to visualize inflammatory tissue damage in multiple sclerosis (MS). The study found that this medium enabled the detection of more inflammatory lesions in MS patients compared to conventional MRI images and contrast media.
Multidetector CT with virtual gastroscopy and post-contrast enhanced multiplanar reformation images help differentiate cancerous lesions from benign ulcer lesions. The study found high specificity in diagnosing malignant gastric ulcers, potentially improving survival rates.
A UNC study found a consistent association between six-month to one-year persistent HPV infections and high-grade cervical lesions or cervical cancer. The study suggests that measuring HPV persistence could optimize screening for cervical cancer by increasing sensitivity while maintaining specificity.
Researchers at Mayo Clinic have developed a high-resolution confocal endomicroscopy probe system that can accurately identify benign colon polyps without removal. The technology was tested in 37 patients and showed an accuracy rate of 98% in flagging non-cancerous polyps.
A large study found incidental adrenal masses on abdominal CT scans to be almost always benign and require no imaging follow-up in low-risk patients. Most lesions were adenomas or myelolipomas, with myelolipomas being more common than previously thought.
A new study emphasizes that six-month short-interval follow-up examinations can accurately detect cancers in patients with 'probably benign' breast lesions, resulting in high sensitivity. This approach avoids unnecessary biopsies and ensures timely cancer detection.
Larger skin lesions are more likely to be melanomas than smaller moles, according to a new study by NYU researchers. The study confirms that an important warning sign of melanoma - moles larger than 6 millimeters - is still valid.
A study published in Archives of Dermatology found that larger skin lesions (over 6mm) are more likely to be melanoma. The findings support the use of diameter guidelines for screening, but also suggest that smaller lesions can still be malignant.
Researchers found that calorie restriction hinders development of pancreatic cancer by reducing levels of IGF-1 and inflammatory signaling proteins. Only 7.5% of mice on the calorie-restricted diet developed lesions, compared to 45% and 57.5% in overweight and obese groups.
A study by Baystate Health found that using mammography and sonography together can exclude breast cancer in 98% of patients. However, some cases may remain undiagnosed due to dense tissue or late detection.
A recent study found that MDCT is accurate in detecting stenosis in small and moderate-sized calcified coronary artery plaque, with a high concordance rate with cardiac catheterization. However, overestimation of stenosis occurred in large and heavily calcified lesions, highlighting the need for caution when interpreting MDCT results.
The Cox-Maze procedure has been enhanced to include an additional ablation, known as the box lesion, which improves patient outcomes by reducing atrial flutter and fibrillation. This new technique also leads to shorter hospital stays and lower use of antiarrhythmic drugs.
Researchers found a three-to-four-fold higher overall prevalence of cerebral microbleeds compared to other studies. The presence of cerebral microbleeds is associated with an increased risk of cerebrovascular problems and may reflect underlying cerebrovascular pathology.
The ABSORB clinical trial demonstrated no stent thrombosis and a low rate of major adverse cardiac events (MACE) in patients with coronary artery disease. The bioabsorbable everolimus eluting stent was shown to be safe and effective, with successful deployment and high device success rates.
Researchers found non-polypoid (flat) colon lesions are relatively common and more likely to contain cancerous tissue than polypoid lesions. The study estimated the prevalence of NP-CRNs to be 9.35% and found that depressed-type NP-CRNs had a higher risk of containing cancer.
A study analyzed eyes of 2520 individuals, finding larger drusen and abnormal blood vessel growth more common in whites. Whites were also more likely to develop advanced AMD and geographic atrophy, with black individuals showing potential protection against AMD.
A recent study by the Hadassah-Hebrew University Medical Center found that only one out of 63 patients with complex fibroadenomas had a malignancy. The researchers concluded that these lesions can be treated similarly to simple fibroadenomas, allowing for non-surgical follow-up.
A study published in Dermatologic Surgery found that chemical peels using alpha-hydroxy acid or beta-hydroxy acid are highly effective in reducing facial acne lesions. Both types of treatments yielded similar results, with BHA having slightly fewer side effects and longer-lasting results.
Researchers found that self-expanding plastic stents (SEPSs) resulted in frequent stent migration, with over 60% of patients experiencing this issue. Long-term symptom improvement was also limited, with only six percent of procedures resulting in long-term resolution.
A study found that melanomas can appear noticeably different from other moles, with 85% of participants identifying them as distinct. The 'ugly duckling' sign may prove a useful screening strategy for primary health care providers and skin self-examination.
A study found that neutralizing IL-22 prevents psoriasis-like disease in mice by reducing skin thickening and inflammatory responses. Administering IL-22 into normal mice induced psoriasis-like skin lesions, supporting the role of IL-22 in the disease.
A study by Yale School of Medicine identified a genetic mutation that expands lesions in the aorta and promotes coronary atherosclerosis. The researchers found that mice lacking the Akt1 gene developed more severe aortic atherosclerosis, highlighting the importance of this gene in regulating endothelial cell development
Research presents findings on plant-derived cancer medicines, highlighting the potential of black raspberry gel in preventing or slowing the growth of oral premalignant tumors. The study demonstrates that the gel slows or reduces lesion progression in about two-thirds of study participants, with no reported side effects.
A recent study found that 318 of 321 benign-appearing adrenal masses were confirmed to be clinically insignificant. The study showed no malignant adrenal lesions, even among patients with other malignancies elsewhere.
A new radiological diagnostic tool called stereo mammography reduces false-positive findings by 49% and missed lesions by 40%. The technology cuts the number of women recalled for additional tests in half, eliminating anxiety for patients and their loved ones.
Stereo mammography has been shown to reduce false positives by 49% compared to standard digital mammography, potentially cutting the number of women recalled for additional tests. The technology produces three-dimensional views of breast tissue, allowing radiologists to better interpret images and detect cancer earlier.
Research at the University of Alabama at Birmingham found that mice exposed to cigarette smoke and fed a liquid diet containing ethanol had a 4.7-fold increase in artery lesions, compared to those breathing filtered air and eating a normal solid diet.
Researchers found that narrow band imaging (NBI) colonoscopy can identify flat dysplastic lesions in ulcerative colitis patients, with a higher positive rate in the tortuous pattern. The study suggests NBI as an alternative to magnifying chromoscopy for cancer surveillance in these patients.
A study published in the Journal of Cancer Epidemiology, Biomarkers, and Prevention found that pre-malignant mammary lesions in dogs and humans display similar characteristics. The research, conducted by Purdue University scientists, could lead to better understanding of breast cancer progression and prevention for both people and pets.
A case of a giant submucosal lipoma located in the descending colon is presented, highlighting key findings such as abdominal pain, bleeding per rectum, and change in bowel habits. The study suggests that colonic malignancy should not be ruled out in patients with significant symptoms.
Dendritic cells help trigger angiogenesis in a mouse model of endometriosis, promoting the growth of tumors and lesions. Targeting dendritic cells may prove to be a promising strategy for treating conditions dependent on angiogenesis.
African-Americans have a higher incidence of colorectal cancer, with advanced polyps on the right side of the colon more common. Latin Americans also show similar high-risk findings to African-Americans in colonoscopy screenings.
A new study found that HPV DNA testing can detect clinically relevant cervical lesions earlier than conventional cytological techniques. This allows for the potential extension of the screening interval by at least one year. Earlier detection reduces the lifetime number of screening tests and referrals, benefiting women.
Researchers aim to improve breast cancer screening by developing new anatomical imaging methods, including MRI and PET, and sensitive histopathologic detection techniques. The goal is to identify precancerous lesions and map their extent for precise surgery.
A study using MR spectroscopy with MRI has successfully identified breast cancers in non-mass enhancing lesions without invasive biopsies. By measuring choline compounds, MR spectroscopy provides specific and sensitive results, reducing the need for unnecessary biopsies.