Research on the medical care of infants and children. Covers pediatric emergencies, blood-pressure thresholds, infectious disease, kidney injury, and developmental health.
A nationwide study reveals that education about firearm safety significantly increases parents' likelihood of asking others about guns in homes their children visit. The research found that caregivers who received information from multiple sources were more likely to ask about firearms, emphasizing the need for ongoing and multifaceted...
A multinational study found that erythropoietin treatment does not prevent death or disability in newborns with critically low levels of oxygen or blood supply to the brain. The research compared outcomes between babies treated with controlled cooling and those receiving both erythropoietin and cooling, but showed no benefit from the a...
A recent study found that children with chronic conditions are hospitalized for respiratory syncytial virus (RSV) at twice the rate as healthy children. Researchers recommend that these children receive immunization against RSV in their first season to increase protection, regardless of maternal vaccination status.
A recent study found that telehealth visits in pediatric primary care significantly reduced antibiotic prescriptions for acute respiratory tract infections. The research analyzed over 540,000 visits and showed that children treated with telehealth were less likely to receive antibiotics than those examined in person.
A new study found that artificial intelligence can better estimate the prevalence of physical abuse in children seen in emergency departments. The AI model correctly identified child abuse in over 35% of cases, outperforming traditional methods that relied solely on diagnostic codes entered by providers or administrative staff.
A new study finds that pregnant women treated with buprenorphine have significantly better health outcomes, including reduced preterm birth rates and lower risk of NICU admission. The research highlights the urgent need for expanded treatment access to vulnerable populations.
The Kosair for Kids Center for Pediatric NeuroRecovery is expanding its facilities to increase treatment capacity by 50%, allowing up to 24 children per day to receive life-changing therapies. The new 12,500-square-foot space will also enhance research collaboration and improve patient care.
A clinical trial found that using EEG to monitor consciousness safely reduced anesthetic use in children, resulting in quicker recovery, reduced delirium, and lower healthcare costs. The study also showed a significant reduction in pediatric anesthesia emergence delirium.
Juvenile-onset recurrent respiratory papillomatosis (JORRP) is a rare disease causing chronic hoarseness and breathing difficulties in children. New clinical guidelines provide actionable recommendations for early recognition, diagnosis, and treatment to improve long-term outcomes.
The Pediatric Academic Societies have awarded 33 Trainee Travel Grants to recognize and support emerging talent in pediatric research. The grants include complimentary registration to the PAS 2025 Meeting and a $500 travel grant to encourage participation.
A large US youth sample shows increased rates of anxiety and depression from 2016 to 2022. In contrast, asthma and severe headaches or migraines decreased in this cohort.
Research from Rutgers Health finds that children exposed to paternal depression at kindergarten entry are more likely to have behavioral difficulties and poor social skills at age 9. Fathers' mental health is crucial in supporting their children's development, and early intervention can help improve well-being for both parents and kids.
A real-world study of 2,147 children with sickle cell disease found that hydroxyurea reduced emergency department visits by 0.36 fewer times per patient-year and hospital stays by 0.84 fewer days per patient-year. Improvements in hemoglobin concentration were seen only in patients who consistently took the medication.
Researchers found that repeated antibiotic use before age 2 is associated with a higher risk for asthma, food allergies, and hay fever later in life. The study suggests that judicious use of antibiotics in children under 2 may impact long-term health outcomes.
The Feihe Pediatric Brain Development Research Initiative at Boston Children's Hospital aims to improve brain development through genetic, nutritional, and environmental factors. The initiative has awarded funding to seven researchers working on projects related to prenatal and postnatal brain development.
Researchers at the University of Missouri's Thompson Center for Autism and Neurodevelopment have found that behavior at 9 months old can indicate a 1-year-old's likelihood of being at risk for autism. Parent surveys reported fussiness, irritability, and difficulty calming down were associated with early signs of autism by 12 months.
Researchers highlight the potential of AI in diagnosing and treating myopia, detecting risk factors and predicting outcomes. However, challenges such as data quality and patient privacy must be addressed to improve widespread clinical application.
The new guideline prioritizes health and quality of life for children and adolescents with obesity, focusing on outcomes such as mental health and cardiovascular risk factors. It recommends a combination of interventions, including nutritional, physical activity, and psychological support, to help manage obesity.
A newly-published Cochrane review found significant gaps in clinical rating scales used to assess pain in newborn babies. The review of 79 studies involving over 7,000 infants across 26 countries revealed that none of the available scales are backed by high-quality evidence.
Eight hospitals, including Oklahoma Children’s Hospital, receive funding to refine discharge processes for mothers and babies with neonatal abstinence syndrome. The program aims to provide continuity of care through prenatally-based education and post-discharge support.
Rutgers Health researchers found that two-thirds of adolescent girls aged 13-17 live in states with abortion bans, restrictive gestational limits, or parental involvement requirements. This leaves them disproportionately impacted without access to abortion care.
Research by Carolyn Drews-Botsch finds that patching after age 4 does not significantly impact vision, but less-aggressive protocols may be suitable for families with distress. Optotype acuity assessments in 4-year-olds can predict visual acuity at age 10.
The Pediatric Long COVID Extension for Community Healthcare Outcomes (ECHO) program has successfully trained nearly 100 healthcare professionals across the US, equipping them to diagnose and manage long COVID in children. The program aims to bridge access gaps and empower community providers.
A new study reveals significant barriers to including non-English speakers in health research, with common reasons including lack of training and budget constraints. Researchers recommend increased access to interpretation and translation services, guidance on budgeting, and methods training to improve inclusion.
A new study found that exosomes from children with pediatric obstructive sleep apnea (OSA) disrupted blood-brain barrier integrity, leading to cognitive impairments. The research suggests a broader impact on barrier function and identifies potential biomarkers for OSA-related neurocognitive dysfunction.
Recent research reveals that avapritinib, a PDGFRA inhibitor, demonstrates potent activity against pediatric high-grade glioma tumors with PDGFRA alterations. Clinical trials in patients showed an initial clinical response and improved survival rates, suggesting the potential for avapritinib as a therapeutic option.
A study using machine learning models found that people with IBD are at risk for premature death when developing other chronic health conditions earlier in life. Chronic conditions like arthritis, hypertension, and mood disorders were common causes of death among those with IBD.
A study found a disproportionate increase in firearm homicide rates among children under 17 and adults over 30 following the COVID-19 pandemic. The peak victimization risk shifted from age 21 to 19, highlighting a change in the association between age and firearm victimization risk.
The Mount Sinai Hospital has launched a new center focused on advancing artificial intelligence (AI) driven outcomes in children's health. The center aims to improve diagnostics, personalize treatments and optimize healthcare delivery for youth and adolescents. Dr. Benjamin S. Glicksberg will lead the Center.
A new study from the University of Colorado Anschutz Medical Campus identified significant mitochondrial dysfunction in lymphoblast cell lines from children with Dravet syndrome, a severe form of epilepsy. The findings suggest that mitochondrial defects play a role in the metabolic dysfunction observed in Dravet syndrome.
Researchers at Dana-Farber Cancer Institute have identified a potential targeted therapy, avapritinib, for pediatric high-grade gliomas. The treatment resulted in tumor reduction and clinical improvement in 3 out of 7 patients with this currently incurable form of brain cancer.
Researchers developed a new diagnostic platform that classifies brain tumors based on the body's cancer-fighting immune response. The approach tailors treatment options to each patient's unique immune profile, offering improved diagnostics and potential for immunotherapies to revolutionize childhood leukemia treatments.
The Chinese Medical Association has released updated guidelines for pediatric mycoplasma pneumoniae infection, emphasizing a multi-faceted diagnostic approach and evidence-based treatment strategies. The guidelines highlight the importance of accurate diagnosis and responsible antibiotic use to combat rising resistance.
The review article examines the relationship between anemia and retinopathy of prematurity, focusing on iron deficiency and underlying molecular mechanisms. Anemia reduces oxygen delivery to the retina, exacerbating hypoxia and promoting pathological neovascularization.
A new approach has been tested, bringing together child health services, specialist care, and the municipality, resulting in faster support for young children with autism. The average age at which children are diagnosed with autism has fallen from three years and eight months to two years and seven months.
A new study found that adenotonsillectomy, a surgical procedure for enlarged tonsils and adenoids, significantly reduces medical office visits and prescription medicine use in children with mild sleep-disordered breathing. The surgery was associated with a 32% reduction in healthcare encounters and a 48% reduction in prescriptions.
A randomized trial found that adenotonsillectomy surgery reduced healthcare utilization in children with mild sleep-disordered breathing by 32% fewer doctor visits and 48% fewer prescriptions. This effective early intervention supports reducing behavioral, neurocognitive, cardiovascular, and cardiometabolic issues.
A recent NIH-supported clinical trial found that adenotonsillectomy significantly reduces medical office visits and prescription medicine use in children with mild sleep-disordered breathing. The surgery was tied to a 32% reduction in health care encounters and a 48% reduction in prescriptions used among participants.
A study by Charité - Universitätsmedizin Berlin and the German Rheumatology Research Center identified the Epstein-Barr virus as the trigger for Multisystem Inflammatory Syndrome in Children (MIS-C). The virus reactivates due to a weakened immune system, leading to an excessive inflammatory response.
A new study found that waist-to-height ratio is more accurate than BMI in estimating body fat in children. The study included 7,600 children and found that 64% of those classified as BMI-overweight had normal fat according to waist-to-height ratio.
A new study reports that Raman spectroscopy, a noninvasive technique, can distinguish between abnormal FCD type II tissue and healthy brain cells with remarkable accuracy. This method could provide real-time guidance for surgeons to more accurately identify and remove affected tissue during surgery.
A responsive parenting intervention demonstrated a significant reduction in child weight outcomes from age 3 to 9 compared to a control group. The intervention's benefits were most pronounced among female participants, and its long-term effects may be sustained with a life-course approach.
A recent study analyzed 44 systematic reviews on pediatric PROMs, highlighting the most recommended tools and identifying gaps in methodological quality. The research underscores the need for more diverse and high-quality studies to improve the selection and application of PROMs in pediatric healthcare.
Researchers develop individualized management strategies for pediatric postural orthostatic tachycardia syndrome (POTS) based on underlying mechanisms like central hypovolemia and hyperadrenergic states. A tailored approach using biomarkers can lead to faster symptom relief, fewer hospital visits, and improved long-term outcomes.
The COVID-19 pandemic has been associated with negative developmental trends in kindergarteners, persisting beyond the pandemic's onset. The study highlights troubling trends in kindergarteners' development before and during the pandemic, underscoring the need for further research.
Researchers at West Virginia University found that babies born to teen mothers weigh less and are smaller for their gestational age. The study highlights the role of social, geographical, and educational factors in teen pregnancy prevention.
The study found that nearly 1-in-3 young people now live with pediatric onset conditions that significantly affect their lives. Young adults are more likely to develop chronic conditions if they have lower socioeconomic status.
Fentanyl poisoning among US children has surged by 924% and 1,506% for teens aged 13-19 over the past eight years. Parents are advised to be vigilant about hidden fentanyl risks and know the signs of overdose symptoms to save their children.
A new study identifies neighborhood amenities, parental mental health, emotional support networks, regular reading routines, and limited screen time as protective factors for improved school readiness. The research highlights the critical role of family routines and parental supports in shaping early child development.
Dr. Sahera Dirajlal-Fargo and Dr. Colleen Fant, both physicians at Lurie Children's Hospital, have been appointed as co-directors of the Center for Global Pediatric Health. The center will focus on collaboration between the Havey Institute for Global Health and Lurie Children's to improve global pediatric health outcomes.
Children who frequently miss school due to abdominal complaints are more likely to have gut-brain axis disorders like IBS, which can be missed by medical tests. The study found that frequent absences were nearly five times more likely to be caused by functional GI disorders than specific illnesses.
The Mount Sinai Parenting Center will expand its marquee programs to educate healthcare providers on social, emotional, and cognitive development during early childhood. The $2.2 million grant will support the training of an additional 30,000 primary care providers through the Keystones of Development Provider Portal.
A community-wide preventive intervention significantly reduced reported cases of both substantiated and unsubstantiated child sexual abuse at the population level. The study's findings suggest that targeted interventions can effectively mitigate child sexual abuse rates.
A recent study found that the NIH provides critical funding for pediatric clinical trials in diseases not prioritized by industry. Pediatric research in asthma and lung diseases has been chronically under-funded, highlighting the need for increased funding.
A new study published in JAMA Pediatrics found that coordinated, community-wide primary prevention efforts can significantly reduce child sexual abuse rates. The study showed a 17% decrease in substantiated cases and a 34% drop in unsubstantiated cases compared to a control group.
Researchers found that omalizumab significantly improved treatment outcomes for multi-food allergy patients compared to oral immunotherapy. A total of 36% of omalizumab recipients could tolerate at least 2 grams of multiple food allergens, while only 19% of oral immunotherapy participants achieved this threshold.
This disorder has diverse etiologies, variable presentations, and different therapeutic responses. The proposed diagnostic algorithm can differentiate pediatric MF subtypes to improve patient outcomes.
Researchers report an increase in adult VZV-related CNS infections, particularly since 2019, with a notable rise in aseptic meningitis cases. The study suggests that universal varicella vaccination may be contributing to the decline in natural immunity, leading to reactivation and CNS complications.
The Global Pediatric Pulmonary Alliance recommends prophylactic mAbs as the best available preventive measure against RSV. A single dose of long-acting mAbs can provide season-long protection to infants, with real-world evidence supporting this strategy.
A recent survey by Northwestern University found that fathers who take at least two weeks of leave are more likely to report their infant being breastfed at eight weeks. Additionally, families where dads took at least two weeks off had a higher rate of continued breastfeeding at eight weeks compared to those with shorter leave.