Articles tagged with Pediatrics
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Researchers have developed an antibody that can identify Campylobacter jejuni and inhibit its growth, reducing pathogenicity. The antibody targets a multiprotein complex essential for the bacteria's energy production, making it a potential target for therapy and vaccination.
Children with medical complexity from rural areas are more likely to receive care at non-pediatric hospitals. The study emphasizes the importance of ensuring all hospitals can provide adequate care for these patients.
The University of Colorado Anschutz Medical Campus has identified key opportunities to strengthen climate education for healthcare professionals. The authors propose a developmental learning model with six interconnected domains that build on foundational skills in communication and collaboration.
This study suggests that gamified digital mental health interventions can be an effective treatment option for youth with ADHD or depressive disorders. The findings provide new information for pediatricians and healthcare professionals seeking innovative solutions for pediatric mental health care.
The American Academy of Pediatrics will host its 2024 National Conference & Exhibition in Orlando, Florida, featuring cutting-edge research and educational seminars on key pediatric health issues. The conference will address topics such as suicide prevention, mental health, and the impact of gun laws on child health outcomes.
Neighborhood food access in early life is strongly associated with child BMI and obesity trajectories. Residence in low-income areas with limited access to healthy food options increases the risk of severe obesity.
Exposure to negative news media about LGBTQ+ topics increases suicidal ideation intensity in the hours following, according to a longitudinal study. The findings have implications for research and intervention in sociopolitical and geographic contexts.
A nationwide multi-cohort study found that residence in low-income-low-food-access neighborhoods during pregnancy or early childhood significantly raises the risk of obesity and severe obesity from childhood to adolescence. The study underscores the importance of early-life neighborhood environments in shaping child health outcomes.
A new study reveals that inpatient food insecurity among caregivers during pediatric hospitalizations is associated with longer hospital admissions and increased odds of readmission. Caregivers experiencing food insecurity were found to have a 2.4 day longer length of stay and 1.8 times higher odds of readmission within 30 days.
The Advisory Committee on Immunization Practices (ACIP) has been instrumental in responding to the COVID-19 pandemic by providing transparent decision-making and prioritizing equitable access to vaccines. The committee's virtual meetings enabled timely discussions and evidence review, allowing for rapid approval of COVID-19 vaccines. H...
A new study finds that excessive social media use is associated with a higher risk of eating disorder symptoms in 9-14-year-olds, including binge eating and distress over weight gain. Problematic screen use may contribute to unhealthy behaviors and addictive tendencies.
Researchers at UCSF identified signals in the metabolic system of infants who died from Sudden Infant Death Syndrome (SIDS), finding associations between lower C-3 levels and elevated C-14OH. Elevated biomarkers also led to reduced risk of SIDS, but further research is needed to validate these findings.
A case-control study found an association between abnormal birth metabolic analytes and sudden infant death syndrome, suggesting potential early risk identification. The study's findings could inform future research and clinical efforts focused on monitoring and preventing SIDS.
Parents who practice proper firearm handling and teach their children to shoot are more likely to store firearms unlocked and loaded, highlighting a potential association between responsible behavior and decreased risk of injury. This study underscores the importance of secure storage practices in reducing firearm-related risks.
A study found that ChatGPT performed better than trainee doctors in assessing complex cases of respiratory disease in areas such as cystic fibrosis and asthma. The chatbot's responses were also scored higher for being human-like, while Google's Bard and Microsoft's Bing performed similarly to or worse than trainees.
A study published by the European Respiratory Society found that hypertonic saline nasal drops reduced the length of the common cold in children by an average of two days. The treatment also reduced the need for medicines during illness and decreased family members catching a cold.
A new AI tool called CAR-E is being developed to provide personalized coaching conversations for medical students and residents, encouraging reflective practice and enhancing their skills. The web-based tool will use a coaching approach to prompt students to think back on their clinical encounters and knowledge gaps.
A study found that pediatricians were more likely to deliver a secure gun storage program when receiving a 'nudge' or extra staff support, resulting in a significant increase from 2% to 49% of doctors. The findings suggest that even minimal resources can be effective in promoting this critical conversation.
A study by the Michigan Child Health Equity Collaborative found significant inaccuracies in racial and ethnic designations in children's medical records, ranging from 22% to 59% for race and 5% to 35% for ethnicity. These errors may undermine efforts to identify health inequities and disparities.
Researchers found that the presence of clinics had the greatest effect on rural children's access to pediatric subspecialists, reducing median driving times by 5-46 minutes. The study suggests expanding outreach clinics can boost access and improve outcomes for children in need.
Researchers developed a tool to identify high-risk children and adolescents with pediatric postacute sequelae of SARS-CoV-2 infection (PASC), also known as long COVID. The study found that symptoms differed by age group, with some similarities but distinct patterns across childhood ages.
Pediatric functional gastrointestinal disorders are complex conditions with a significant impact on children's health and quality of life. The ROME IV criteria facilitate earlier and more accurate diagnosis, while a multidisciplinary approach to management offers hope for improved outcomes.
A recent review by Imperial College London suggests that Nigeria's high infant mortality rate could be addressed through the adoption of existing scientific breakthroughs and technological advancements. The review highlights several low-cost advances in neonatal care developed by Nigerian clinicians and researchers, including adaptive ...
Researchers found that approximately 60% of genetic changes driving T-ALL cancer cells are non-coding changes, significantly altering the understanding of disease biology. This leads to innovative treatments, including new immunotherapies developed at CHOP and St. Jude.
A new screening tool, DuMAND Checklist, has shown promise for assessing neurobehavioral difficulties in children with Duchenne muscular dystrophy and improving quality of life. The checklist covers a range of issues including behavior, psychiatric disorders, and cognitive deficits.
A study by Children's Hospital of Philadelphia researchers found discrepancies between crash reports and hospital data, suggesting incomplete or inaccurate pictures of child passenger safety. The findings emphasize the importance of enhancing injury data quality to assess transportation safety strategies.
A nationwide children's hospital implemented an automated Caring Contacts texting system to provide ongoing care and support to youth at risk for suicide. The intervention helped patients feel hopeful and supported, with 83% reporting feeling moderately to very hopeful and 88% feeling moderately to very supported.
A recent study found that water beads have more than doubled the number of emergency department visits by children in the US from 2021 to 2022. The increase in ED visits is alarming, with over 8,000 cases reported between 2007 and 2022.
A study of nearly 30,000 US caregivers found that comprehensive mental health coverage laws reduced difficulties in accessing care for children. Caregivers from diverse backgrounds faced more challenges, highlighting the need for culturally sensitive services.
Researchers discovered novel genetic variations that influence relapse risk in children with standard-risk B-cell acute lymphoblastic leukemia (SR B-ALL). The study highlights the importance of genomic profiling in accurately determining patient risk and tailoring treatment intensity.
Child tablet use at age 3.5 years was associated with more expressions of anger and frustration by the age of 4.5 years, suggesting a potential cycle deleterious for emotional regulation. Later, child proneness to anger/frustration at age 4.5 years was linked to increased tablet use by age 5.5 years.
Researchers found that children's immune systems attacked their own tissues after latching onto a coronavirus protein resembling one found in multiple organs. Early intervention was crucial to prevent death in these cases, and the study has implications for understanding other autoimmune diseases.
A recent study published in JAMA Network Open demonstrated the effectiveness of AI in detecting myopia, strabismus, and ptosis using smartphone images. This technology has the potential to facilitate early detection of pediatric eye diseases in a convenient and accessible manner.
This study highlights small to moderate effect sizes of early childhood screen use on cognition and social skills, emphasizing the importance of considering context when making recommendations; intentional and productive screen use, age-appropriate content, and co-use with caregivers are key factors.
A cross-sectional study of 13,000 pediatric emergency department visits found that school reopening after a COVID-19 disruption was associated with an increase in acute psychiatric emergencies. School stress may be a significant factor in youth mental health, highlighting the need for further investigation into mediating factors.
A new study has shown that a drug developed for pancreatic cancer is effective in treating the most aggressive form of medulloblastoma, a childhood brain tumor. The drug, Minnelide, reduced tumor growth and increased the efficacy of chemotherapy, offering hope for improved survival rates for children with this disease.
The St. Jude gene panel is a cost-effective test that categorizes childhood malignancies and guides patient treatment by sequencing 0.15% of the human genome. The panel outperforms existing cancer gene panels, providing 90% coverage of pediatric cancer driver genes.
Infants born to mothers with obesity are at higher risk of SUID due to a dose-dependent association between increasing maternal BMI and SUID risk. Research suggests that maternal obesity should be added to the list of known risk factors for SUID.
A new study published in the journal Brain Connectivity reveals how psychological resilience can aid children's recovery from concussions. The research found that building resilience through supportive family environments and effective coping strategies may help young patients heal faster.
Researchers found a significant association between the KIT M541L variant and mastocytosis diagnosis in patients with systemic and cutaneous mastocytosis. The variant was identified in 19 individuals, mostly diagnosed with systemic mastocytosis, but without significant differences in symptomatology.
Researchers evaluated the implementation of a virtual driving assessment in primary care settings, resulting in promising initial results with over 75% of teens recommending the assessment to friends. The tool measures driving skills in common serious crash scenarios, providing personalized feedback to families on areas for improvement.
A new national study found that leaving phone notifications on leads to less sleep compared to turning the phone off or keeping it outside the bedroom. Adolescents are highly sensitive to phone notifications, which can disrupt their sleep patterns.
A Cleveland Clinic-led study found that maternal Zika virus infections can reprogram fetal immune development, leading to long-term consequences in children's immunity. The changes occur even in children born without physical or neurological symptoms of congenital Zika syndrome, suggesting a broader impact.
A recent study published in JAMA Pediatrics highlights the critical role of family support in maintaining the mental health of transgender youth following gender identity milestones. Without a supportive family environment, these young individuals are at a higher risk of attempting suicide or running away from home.
A study published in BMJ Public Health found that children living in deprived areas have a three times higher risk of needing dental extractions under general anaesthesia. This highlights the need for targeted interventions and improved access to preventive dental services to address socioeconomic and ethnic inequalities in oral health.
A study from Children's Hospital of Philadelphia found that LGBTQ+ youth are more likely to experience depression and suicidal thoughts compared to their non-LGBTQ+ peers. However, those who reported parental support showed significantly reduced rates of these symptoms.
A study found that 1 in 6 youths fill an opioid prescription prior to surgery and 3% continue using them three to six months later. Persistent opioid use among adolescents is a concern due to genetic, neurobiological, and social vulnerabilities.
Despite overall improvement, US children's diets remain suboptimal, with total dietary quality scores below the 5-point threshold. The study analyzed data from 2005-2020 and found that the increase remained lower than expected.
A study published by Nemours Children's Health and Endeavor Health found that states with high COVID-19 vaccination rates saw a significant decrease in pediatric asthma symptoms, with the largest decline seen in the highest quarter of vaccination rates.
A recent study investigated COVID-19 vaccine exposure in the first trimester and its potential impact on major structural birth defects. The results indicate that mRNA COVID-19 vaccine exposure during this period is not associated with an increased risk for selected birth defects among live births.
Researchers found that frequent respiratory infections in children may have elevated their innate immune activity, protecting them from severe COVID-19 symptoms. The study suggests that childhood exposure to common cold viruses and bacteria boosted the kids' immune systems, allowing them to better fight off SARS-CoV-2.
Nearly 20,000 US youth deaths could be avoided if US infant mortality rates matched those of 16 comparison countries. The study highlights the need for improved healthcare and interventions to reduce US youth mortality rates.
Research by a University of Virginia undergraduate may help explain recurrent Crohn’s disease in children and open the door to new ways to treat or even cure the devastating condition. Children with relapsing Crohn’s had persistent disruptions of their microbiomes even after inflammation was successfully controlled.
The policy statement offers guidelines for institutions and medical professionals to weigh benefits and risks of imaging in emergency departments. It includes recommendations for deferring imaging in children transferred to pediatric referral centers and using shared decision-making strategies when multiple reasonable choices exist. Th...
New research suggests that neighborhoods with more educational and socioeconomic opportunities can improve infants' brain activity and cognitive development. Infants in such neighborhoods show greater brain function at six months of age and better cognition at 12 months old.
A study by Children's Hospital of Philadelphia researchers found that elementary age children are more likely to experience concussions during recreation and other non-sport activities. These injuries often lead to longer recovery times due to delayed specialist care. The findings highlight the need for education and awareness about co...
A survey of pediatric bariatric surgeons found significant variation in the use of weight loss medications, particularly GLP-1As, in young patients. Most respondents prescribe GLP-1As for patients considering MBS, but preoperative and postoperative practices vary widely.
Researchers from Children's Hospital of Philadelphia found that two assessments, Leiter-3 and Vineland Adaptive Behavior Scale, can help measure cognitive function in children with Aicardi Goutières Syndrome. The study revealed that a subset of patients scored within a normal IQ range, paving the way for future clinical trial design.
Researchers found that starting resuscitation with high concentrations of oxygen (90% or greater) can increase survival chances for premature babies. The study examined over 1,000 premature babies and found a significant reduction in mortality rates by using higher oxygen levels.
A new study found that Texas' 2021 ban on abortion in early pregnancy was associated with unexpected increases in infant and neonatal deaths in Texas between 2021 and 2022. Congenital anomalies also surged in Texas, but not elsewhere in the US.