Integrating automated smoking cessation interventions into pediatric primary care significantly increased treatment received and reduced cigarettes smoked among parents. The study found that the interventions led to a greater reduction in cigarette use, improved quit rates, and increased health navigator support.
The Gabriella Miller Kids First Pediatric Research Program has released its 36th study, introducing significant new data updates to two existing studies. These advances aim to uncover the genetic foundations of childhood cancers and congenital conditions. With over 110,000 data files available, researchers can explore publicly accessib...
A new study found that the end of COVID-era federal funding led to a significant increase in uninsured children visiting emergency departments in Texas, with 45.2% more visits than before. The share of commercially insured patients also rose 12.5%, while Medicaid-insured visits declined by 11.7%.
A new study from Memorial Sloan Kettering Cancer Center shows the Make-an-IMPACT program improves global access to genomic testing for pediatric cancer patients. The program helps develop an experimental antibody that shows promise against metastatic cancer. Researchers also shed light on the origins of ERG-driven prostate cancer and f...
A new study found that fewer than half of children with sickle cell disease and Medicaid in Michigan received dental services. Dental health is crucial for these children due to the reciprocal relationship between the disease and oral infections.
A study by Professor Chunxiu Gong's team identified the clinical presentation of Cornelia de Lange syndrome (CdLS) and genetic alterations in Chinese pediatric patients. The researchers found that 12 patients presented with classic CdLS, while others showed global developmental delays and growth retardation.
Researchers found neglected children had abnormalities in critical brain regions, including right corticospinal tract and superior longitudinal fasciculus, linked to behavioral difficulties. These findings provide objective markers for identifying children affected by neglect.
A Stanford Medicine-led study found that many young children with ADHD are prescribed medication just after diagnosis, contradicting treatment guidelines. The study highlights a gap in medical care for 4- and 5-year-olds with ADHD, who should try six months of behavior therapy before starting medication.
Researchers discovered that GLP-2 analogs reshape the intestinal environment by expanding villi and crypts, increasing regulatory T cells, and improving nutrient absorption. This breakthrough offers new hope for patients with short bowel syndrome and potentially benefits immunocompromised individuals.
Researchers at Children's Hospital of Philadelphia found that certain lipids in obesity-causing foods cause asthma-like lung inflammation. The study suggests that modifying dietary choices and repurposing existing drugs could help treat this type of asthma, which is more likely to send patients to the hospital.
According to UMass Amherst research, only 16% of US counties offer access to vaginal labor after C-section. Despite the American College of Obstetricians and Gynecologists' guidelines supporting this option, access remains limited due to factors such as hospital availability and provider comfort.
Children living in low-opportunity neighborhoods are more than 20 times likely to be hospitalized for gun injuries compared to those in high-opportunity areas. Unintentional shootings account for the majority of these cases.
A recent study found that large portions of obesity-related conditions in US adolescents and young adults are attributable to obesity. Treating and preventing obesity may reduce these conditions and associated costs. The researchers emphasize the importance of addressing childhood obesity to prevent future health issues.
A study suggests that children's depression may contribute to worsening maternal depression, rather than the other way around. This finding highlights the need for family-centered approaches to mental health care.
The study found a significant reduction in mortality while waiting for a new heart, despite increased waiting times. Technological advances and improved healthcare practices are credited with the improvements.
Researchers from the University of Pennsylvania School of Veterinary Medicine and Children's Hospital of Philadelphia discovered a link between mitochondrial dysfunction in the blood-brain barrier and neuropsychiatric disease in patients with 22qDS. Treatment with bezafibrate, a cholesterol drug, may enhance BBB function and correct so...
A three-year-old girl has been successfully treated with the first-ever FDA-approved gene therapy treatment for AADC deficiency, a rare inherited neurological disorder. The treatment, Kebilidi, is expected to take 2-6 months to show measurable impact and has already shown signs of increased energy and happiness.
The Society for Cardiovascular Angiography & Interventions (SCAI) has published a new position statement providing best-practice guidance for the treatment of patent ductus arteriosus (PDA) in premature infants using transcatheter occlusion. The guidance emphasizes patient selection, pre-procedural planning, and post-procedure follow-u...
Pediatric orthopedic surgeons at Ochsner Children's perform the first robotic-assisted pediatric spine deformity surgery in Louisiana using Globus Medical's ExcelsiusGPS technology. The procedure enables unprecedented surgical precision and accuracy, improving patient outcomes.
Pediatric high-grade glioma tumors have unique genetic patterns that can be targeted by immunotherapy. Researchers identified a specific protein structure, NRCAM, that is essential for cancer cell migration and invasion, making it an attractive target for new treatments.
A prospective study found that better control of inflammation during childhood leads to less stiffening of the esophagus and fewer disease complications. The study suggests that stiffness of blood vessels in the esophagus could be an important biomarker for disease progression, indicating which patients may benefit from current therapies.
A pediatric investigation study reveals that male fetuses prioritize growth while female fetuses focus on placental development under gestational hypertension. The findings support the growth strategy hypothesis and suggest sex-specific differences in fetal responses to prenatal stressors.
A new national survey finds that nearly a third of parents (30%) report their child missed more than a week of school due to fear or anxiety. The Kids Mental Health Foundation offers free resources to help parents and caregivers understand and manage school avoidance.
Key findings show a decline in childhood and adolescent immunization rates in Michigan, with completion rates dropping sharply during the COVID-19 pandemic. The study highlights the need for targeted efforts to increase immunization rates in counties with lower income and higher uninsurance rates.
A new precision genomics initiative is launching to improve pediatric cancer diagnostics and research. The BrightSeq platform aims to deliver actionable genomic findings to care teams while accelerating research through robust sample acquisition.
St. Jude receives its third consecutive Magnet designation and first Magnet Designation with Distinction, recognizing its commitment to exceptional nursing care and patient outcomes. The hospital's nursing programs, including the Nurse Residency Program and Center of Advanced Practice, have contributed to its success.
Researchers conducted a randomized clinical trial to compare low- and high-dose methylprednisolone with azithromycin for treating severe Mycoplasma pneumoniae pneumonia. The study found that lower dose regimen of glucocorticoids is sufficient, equally effective, and safer than the high dose regimen.
A new study by Children's Hospital of Philadelphia researchers has found that eye-tracking metrics can help identify concussion-related vision disorders in patients with persisting post-concussive symptoms. The study used an objective infrared eye tracking device to measure gaze positions and found a significant correlation between the...
A Stanford Medicine-led report found that children with rare flu complications like influenza-associated acute necrotizing encephalopathy (ANE) need prompt treatment to survive. The condition causes brain swelling and a runaway immune response, leading to fatal outcomes if left untreated.
A European study analyzed data from over 30,000 children with brain tumors, providing a clear overview of their survival outcomes. The study found that differences in survival rates between countries are smaller than previously thought, suggesting improved access to similar treatments across Europe.
A combination of technological interventions is required to prevent children from dying in overheated cars, according to a new study. The researchers identified exemplar scenarios that led to pediatric vehicular heatstroke and found that no single technology can prevent all cases.
A new study reveals that infants, toddlers, and preschoolers can exhibit distinct long COVID symptoms, which may be challenging to identify due to their unfamiliarity. The study emphasizes the importance of pediatricians and family physicians considering long COVID in children presenting with similar symptoms.
A $1.1 million grant supports a natural history study for MCHS, collecting vital information about the condition to inform future clinical trials of therapies. The Volāre Study aims to provide baseline developmental trajectory information and establish infrastructure for multicenter clinical trials.
Research reveals that prenatal PFAS exposure can alter infants' developing immune systems, leading to lasting imprints on their ability to fight disease. Exposure to low levels of PFAS was associated with changes in key T-cell populations, including T follicular helper cells and regulatory T cells.
A new report reveals that one in five parents experience potty anxiety during toilet training, while another one in five finds the process harder than expected. Parents cite various reasons for starting potty training, including readiness signs, daycare or preschool requirements, and cost pressures.
ADLM 2025 will tackle urgent topics like clinical AI integration and fake medical news, as well as leveraging genomics for personalized healthcare. The meeting also explores the health threat of plastics and microbiome medicine to combat diseases.
The study found a significant increase in extremely severe obesity among US children and adolescents, leading to severe metabolic and cardiovascular complications. Extremely severe obesity was linked to conditions like metabolic dysfunction-associated steatotic liver disease, prediabetes or diabetes, and metabolic syndrome.
A systematic review found that optimal childhood heart health metrics, including diet, physical activity, and sleep, lead to lower risks of chronic diseases in adulthood. The review highlights the importance of early prevention and suggests that parents can focus on healthy habits and regular check-ups with pediatricians.
This study found that Black and Hispanic children were disproportionately hospitalized for COVID-19 and experienced severe disease compared to white and Asian or Pacific Islander children. Children with underlying medical conditions from these groups also had a higher proportion of hospitalizations.
A study published in Pediatrics reveals a sharp surge in nicotine pouch ingestions among young children, with a 763% increase in rate of reported cases between 2020 and 2023. The ingestion rates for other nicotine products declined during the same period.
A study by The Endocrine Society reveals that children with growth hormone deficiency experience improved overall health and coping mechanisms when their caregivers report reduced stress, anxiety, and depression. Conversely, caregivers' emotional stability is associated with better outcomes for the child.
Researchers developed a non-invasive questionnaire to identify children at risk of maltreatment, highlighting seven behavioral problem areas linked to maltreatment. The study found critical timing patterns and type of abuse matters, offering a more comprehensive approach to support maltreated children.
Recent studies reveal disparities in access to hepatitis C treatment for children and recently pregnant women, with significant racial and geographic disparities. The studies highlight the need for targeted resources to reach these vulnerable populations.
Research found that premature babies who had early skin-to-skin contact with their mother were more likely to be breastfed at discharge and for up to one year. Early contact also promotes bonding, reduces stress, and supports long-term development.
A study using AI language models analyzed sentiments and emotions expressed by almost 400 pediatric patients on social media, finding that 94% of comments were negative, with sadness and fear prevalent. The study highlights the need for integrated care approaches to support vulnerable young patients managing complex medical conditions.
A Northwestern University study finds disparities in peanut allergy prevention guidance, with low-income and minority parents less likely to receive accurate advice. Early peanut introduction cuts allergy risk by over 80%, but guidance is often inadequate for these families.
A new study predicts postoperative complications in children up to three days before formal diagnosis using wearable device data and novel metrics related to circadian rhythms. The results show 91% sensitivity and 74% specificity, indicating potential for facilitating faster treatment and care.
The Center will develop personalized CRISPR on-demand treatments for children with severe inborn errors of immunity and metabolic disease. The initiative aims to make CRISPR cures more affordable and accessible, building on recent clinical success in treating ultra-rare genetic diseases.
A new study by Children's Hospital of Philadelphia researchers found that US children's health is declining across multiple measurements. Chronic illnesses, physical and mental health conditions, and increased mortality rates were observed compared to other high-income nations.
Researchers developed an in-silico meta-analysis tool to determine optimal laser irradiation conditions for treating nevus of Ota. The study found that picosecond laser treatment demonstrated higher efficacy and equivalent safety compared to nanosecond laser treatment.
The study reveals that many people are unaware of two crucial facts that can help reduce SIDS deaths: putting babies on their backs to sleep, and avoiding secondhand smoke in the home. The survey found that only 65% know that a baby should be put to sleep on its back, highlighting a need for increased education and awareness.
The study found a statistically significant increase in hospital admissions due to pediatric clavicular fractures over the 10-year period, suggesting an increase in severity of those injuries. This calls for better injury prevention and management strategies for doctors, parents, and patients.
Researchers developed an innovative FENCY ligation technique combined with preoperative embolization to remove giant plexiform neurofibromas, reducing risk of complications and improving recovery time. The study results in significant functional improvement and high patient satisfaction rates.
A groundbreaking study has uncovered the unique architecture of cells and signals inside the joint as inflammation takes hold in children with arthritis. The research provides a new way forward for understanding this condition, which affects over 10,000 children in the UK.
A new software tool called VR-Omics has the potential to further our understanding of other childhood diseases. The technology can identify previously undetected cell activities of cardiac rhabdomyoma, a type of benign heart tumour that can cause respiratory distress and irregular heartbeat.
A recent study found that 85% of commercially insured deaf children with cochlear implants use spoken language, compared to 33% of Medicaid-eligible children. Family language was not a significant factor in spoken language development.
A scoping review highlights Europe's fragmented efforts in biliary atresia screening, calling for a unified approach that merges effective tools with innovation. The review assesses three major screening strategies: stool color cards, serum bilirubin testing, and biochemical profiling, emphasizing the potential of digital apps and AI-p...
The study found that the stage of normal cell development at which B cells transform into leukemic cells impacts treatment outcomes for pediatric patients with B-cell acute lymphoblastic leukemia (B-ALL). Researchers identified a 'multipotency score' to predict clinical outcomes, providing valuable insights into drug resistance and str...
A Mount Sinai study found a post-pandemic increase in head and shoulder injuries among female and male youth hockey players, with higher rates of hospitalizations and fractures. The research highlights the importance of safer equipment standards, injury prevention strategies, and education to protect young athletes.
A new UVA Health study finds that stocking two twin packs of epinephrine autoinjectors and having campers leave their own at home is the most cost-effective strategy for residential camps. This approach comes with an estimated overall cost of $4.33 per camper.