Research on the medical care of infants and children. Covers pediatric emergencies, blood-pressure thresholds, infectious disease, kidney injury, and developmental health.
Research from 2008-2020 shows an increase in emotional/mental health and suicide prevention in schools, but a decrease in substance use prevention, particularly among middle schools. This shift highlights the need for targeted teacher training and resource allocation to address emerging trends in school mental health.
Researchers found that children with primary ciliary dyskinesia (PCD) are 22 times more likely to have asthma compared to those without PCD characteristics. The study suggests that some children diagnosed with asthma may have undiagnosed PCD, particularly if they exhibit unique respiratory symptoms.
Racially and ethnically minoritized US children experience disparities in mean levels and variability of sleep compared to white peers. These findings emphasize the importance of addressing multiple sleep dimensions across diverse racial and ethnic groups to achieve equitable pediatric sleep health.
A new study from the University of Missouri-Columbia found that socioeconomic status and education level are associated with lower odds of children receiving CPR and surviving after experiencing a cardiac arrest. The study analyzed 21,137 data entries across 54 states and territories in the United States.
The study analyzed the high burden of RSV-associated acute respiratory illness among young children in the U.S. and found nirsevimab to be effective against severe cases, highlighting the potential for substantial public health impact through increased prevention coverage.
Researchers developed an interactive screening model called RITA-T, which improved early identification of high-risk toddlers from underserved areas. The study found that toddlers screened via RITA-T had shorter wait times and more accessible diagnostic services compared to those not using the model.
The collaboration aims to develop regulatory science tools, including open-source models and datasets, to facilitate the technical evaluation of pediatric and perinatal medical devices. Children's National will contribute its expertise in research and innovation, particularly in data analytics, to support the development of these tools.
Research reveals transgender and gender-diverse preteens are 15% less physically active than cisgender peers, with 1,394 fewer steps taken daily. This disparity may be due to stigma and discrimination discouraging team sports participation.
This special issue of Calcified Tissue International presents a collection of critical reviews and original research articles on osteogenesis imperfecta (OI), covering essential aspects of the condition, including its nosology, genetics, and clinical presentation. The contributions also discuss treatment strategies for both children an...
Allophone children who attended preschool services show improved cognitive development, social emotional skills, and communication abilities compared to those who did not. Preschool education is a key factor in bridging the language gap for these children.
A study published in the Journal of the American College of Surgeons found that using antibiotics alone to treat children with uncomplicated appendicitis is a cost-effective and safe alternative to surgery. This approach resulted in lower costs and similar quality-of-life scores compared to upfront surgery.
A study published in PLOS ONE found that antimicrobial photodynamic therapy using annatto colorant was effective in treating halitosis in mouth-breathing children. The researchers used a LED light source to target the annatto, which generated reactive oxygen species that killed bacteria on the tongue, leading to improved oral health.
Children's Hospital of Philadelphia researchers discovered a gene signature that identifies patients with T-ALL at high risk of relapse. The study found a potential therapeutic treatment, venetoclax, which targets specific cells associated with poor outcomes.
A new XR simulator has been introduced to equip nursing students with skills needed in caring for children requiring mechanical ventilation and tracheal suctioning. The simulator, Simmar+ESTE-SIM, combines physical equipment with computer programs to provide comprehensive training.
The Greenlight Plus trial found that technological interventions and policies can help prevent childhood obesity at an early age. The study suggests that targeted prevention efforts can reduce the risk of obesity in children, setting a promising foundation for future prevention strategies.
Adolescents who snore frequently exhibit behavior problems like inattention and rule-breaking, but not cognitive decline. The study tracked nearly 12,000 children from age 9-10 to age 15, finding no correlation between snoring and reduced cognitive abilities.
A cohort study found that a prenatal diet aligned with US Dietary Guidelines was linked to slower infant growth rates and lower obesity risk. The study suggests that improving prenatal nutrition may also benefit children's growth trajectory in the long term.
A new North American population-based study found preterm birth associated with higher mortality risks throughout life, especially during infancy and early childhood. Researchers identified a range of causes contributing to the increased mortality risk after preterm birth.
The Heart Institute is celebrated for delivering unparalleled treatment and support to children with heart conditions. It has consistently provided high-quality cardiac care and specialized disease management for all forms of cardiomyopathy.
A brain-based condition causing vision problems in children has been defined by a NIH-led team. The five elements of cerebral (or cortical) visual impairment (CVI) include difficulty visually searching for objects or understanding complex motion.
A new study by Nemours Children's Health researcher finds that caregivers of prenatally exposed infants are twice as likely to be impaired at the time of death. Targeted efforts to prevent SUID in these infants are needed, with clear messages delivered to parents and caregivers emphasizing safe sleep practices and substance use prevent...
Researchers propose a new working definition for CVI, a leading cause of blindness and visual impairment in children. The definition is based on five key elements and includes early detection, neuroplasticity, and functional deficits.
The EMA's orphan designation for G2B-002 marks a significant milestone in the fight against pediatric brain tumors. The innovative product leverages Gate2Brain's proprietary technology to enhance drug delivery across the blood-brain barrier, promising enhanced effectiveness and safety for complex cancer treatments.
Dr. Beth Tarini receives the award for her clinical and research interests in genetic testing in pediatric care, including delivery of care following positive newborn screenings. She is a nationally recognized leader and scholar who supports growing child health research workforce.
Researchers have identified three distinct subtypes of Chiari type-1 malformations with distinct characteristics, enabling physicians to develop treatment protocols for patients. The study used artificial intelligence to analyze data from over 1,200 patients and identified patterns that can inform medical decision making.
Dana Bledsoe joins Ochsner Children's as CEO, bringing extensive leadership experience and a commitment to nurturing children's dreams. With her unique approach to creative problem-solving and advocacy for team development, she aims to build a compassionate and innovative environment.
Global experts and medical professionals gathered in Tashkent to address rare diseases, enhancing patient care. The forum highlighted key findings on diagnosis and treatment of rare genetic disorders in Uzbekistan.
The 2024 Guidelines for First Aid provide critical updates on recognizing and responding to mild, moderate, and life-threatening emergencies. The guidelines offer enhanced guidance on managing opioid overdoses, bleeding, and other conditions, as well as improved recommendations for emergency care involving children.
A new study found that standardized autism screening during pediatric well-child visits identifies more children with high autism likelihood at a younger age. The study used the Modified Checklist for Autism in Toddlers, Revised, with Follow-Up (M-CHAT-R/F) and compared it to usual care.
Researchers discovered artemisinin partial resistance in Ugandan children with complicated malaria linked to the Pfkelch13 A675V genetic variation. This finding also highlights concerns over suboptimal treatment efficacy of parenteral artesunate followed by oral artemether/lumefantrine therapy.
New research shows that routine symptom screening using a validated tool (SSPedi) can reduce symptom burden and support implementing care pathways for improved symptom management. This study found a clinically meaningful decrease in total symptom score, with 12 of 15 symptoms measured showing significant improvement.
A unique COVID-19 and flu vaccine clinic at the UC Davis MIND Institute has shown remarkable success in increasing vaccination rates among individuals with neurodevelopmental disabilities. The clinic's innovative approach, which incorporates community partners and tailored care plans, has resulted in a 99.3% success rate over two years.
The updated guidance reaffirms the importance of CPR with breaths for resuscitating individuals who have drowned. It also highlights the need for prevention, recognition, and safe rescue to improve chances of survival. The recommendations are based on evidence-based practices to restore breathing and blood circulation.
The American Pediatric Society has welcomed 98 new members for 2025, including outstanding advocates, scholars, educators, and clinicians. These individuals have distinguished themselves as child health leaders and are making a significant impact on the lives of children throughout North America and the world.
Children with asthma show lower scores on episodic memory tasks compared to their peers without the condition. Earlier onset and longer duration of asthma also contribute to slower memory development over time.
A cohort study found asthma to be associated with memory difficulties in children, which may impact executive function abilities. Earlier asthma onset is likely to exacerbate these effects.
This study reveals prevalent adverse childhood experiences among children, including abuse and neglect, with notable disparities across demographics. Early identification and community interventions can reduce ACEs and mitigate future health consequences.
A recent study found that over a quarter of new mothers have fallen asleep while feeding their babies, increasing the risk of sudden infant death syndrome (SIDS). Researchers are urging care providers to inform new moms about the potential risks and provide guidance on safe feeding practices.
A longitudinal cohort study found no significant associations between prenatal SARS-CoV-2 infection and child neurodevelopment outcomes in the first two years of life. Follow-up research is needed to determine if these effects persist into later childhood.
A new study published in The Lancet Child & Adolescent Health found that children living in areas with a high burden of tuberculosis have a consistently high annual risk of developing TB infection throughout childhood. By age 10, over 10% of children developed TB disease.
The American Pediatric Society recognizes Dr. Maria Trent's outstanding contributions to advancing child and adolescent health, well-being, and equity through quality improvement, advocacy, practice, or research. Her work has forged many collaborations on various facets of adolescent sexual health across multiple disciplines.
A digital health behavior intervention improved child weight-for-length trajectory and reduced childhood obesity at 24 months. The intervention was effective in a racially and ethnically diverse population, including groups at elevated risk for childhood obesity.
A new study found that improving pediatric emergency care readiness can prevent up to 2,143 child deaths annually with modest financial investment. The research suggests an annual cost of $3 per child can save approximately 30 lives in Oregon.
A study reveals that infant gut microbiota succession is predictable and malleable, allowing for the shaping of gut health through birth mode and feeding practices. This research has significant implications for reducing childhood allergic diseases, overweight, and respiratory infections.
The American Academy of Otolaryngology calls on battery manufacturers to produce safe button or coin cell batteries to mitigate life-threatening risks. Swallowing a battery can cause severe burns, perforations, and damage to the esophagus, trachea, or major vasculature.
A large-scale clinical trial will enroll 644 children across the US to determine if adding acetaminophen or ketorolac to opioid-based pain control reduces pain in critically ill children. The study aims to improve pediatric intensive care worldwide by reducing side effects and increasing long-term patient outcomes.
The project aims to reduce inappropriate antibiotic prescribing rates for children with acute respiratory tract infections, linked to adverse health events and antibiotic resistance. The program will provide tools and education to support providers in using narrow-spectrum antibiotics only when necessary.
Researchers at Children's Hospital of Philadelphia identified disparities in pediatric concussion care, finding that non-Hispanic Black children and those with public insurance are more likely to be seen first for a concussion in the emergency department. This suggests that establishing up-to-date community-level resources could improv...
Dr. Bonnie W. Ramsey is recognized for her significant contributions to advancing child health and the profession of pediatrics. Her work on cystic fibrosis has dramatically improved life expectancy for children with the disease.
A US cohort study found that prenatal cannabis exposure was associated with differences in executive function and aggressive behavior in children at age 5. The study's results may inform clinical recommendations on cannabis use during pregnancy.
Research from Karolinska Institutet finds that abnormal BMI in children can lead to impaired lung function, but normalizing BMI before adulthood may offset this. The study, which followed over 4,000 children, also found a correlation between low BMI and reduced lung growth.
Using state-of-the-art technology, researchers identified specific steps needed for CRISPR to become active and perform its gene editing function. Understanding these mechanisms could lead to improved designs for CRISPR-based gene editing.
Researchers at Nationwide Children's Hospital found prenatal cannabis exposure associated with poorer thinking skills and behaviors like impulse control and aggression in preschool-aged children. The study supports existing clinical recommendations against cannabis use during pregnancy due to potential health risks.
A cohort study of children with vesicoureteral reflux found that glomerular filtration rate changes after urinary tract infections. The study used data from the Children With Vesicoureteral Reflux trial to assess estimated glomerular filtration rate changes in participants with vs without recurrent UTIs.
A survey of 298 parents with children diagnosed with atopic dermatitis found that parents' understanding of the condition and its dietary links significantly influenced their children's diets. The most frequently identified trigger foods were milk, tree nuts/seeds/peanuts, and eggs.
A study found that anxiety related to food allergies increased significantly in children, leading to an average of 2.1 allergens per patient and a 69% incidence of food-related anxiety. Psychology referrals for these patients increased by 50% over four years, with 60% completing at least one appointment.
Researchers have successfully integrated genome sequencing into newborn screening to identify hundreds of rare genetic disorders. This approach allows for earlier diagnosis and treatment, promoting health equity and reducing time to diagnosis.
A pioneering study shows that DNA analysis picks up many more preventable and treatable serious health conditions than standard newborn screening, improving children's medical care. Genome sequencing detects gene variants linked to hundreds of specific diseases, far exceeding the 60 disorders detected by current methods.
Researchers found that brief interventions with core physician teams boosted internal coordination, leading to better learning and productivity among trainees. Team coordination with external roles, such as nurses, also enhanced trainee learning and patient stays were shorter.
Scientists have discovered a long non-coding RNA called CHASERR that regulates the production of the CHD2 gene, which is associated with neurodevelopmental disorders. The study found that patients with a deletion of this RNA had excessive CHD2 protein production, leading to severe intellectual delays and other symptoms.