Research on what raises a person's risk of disease and injury. Covers cardiovascular and aneurysm risk, medication in pregnancy, youth behavior, and suicide risk.
The ENIGMA Initiative aims to bridge knowledge gaps on brain aging factors in developing countries, particularly in India. The study will collect comprehensive data on risk and protective factors through clinical interviews, bloodwork, and brain MRI to identify universal and population-specific predictors of dementia.
Researchers at Gladstone Institutes found that ApoE4 from neurons plays a critical role in Alzheimer's disease, contrary to previous focus on glial cells. The study shows that deleting ApoE4 from neurons reduces brain changes resembling Alzheimer's disease, offering new possibilities for treatment.
Researchers found that a combination of symptom and high-level viral rebound after untreated COVID-19 infection is rare, occurring in only 3 percent of study participants. This suggests that accounting for underlying rates of symptom relapse is crucial when evaluating antiviral treatment effects.
A new study from Trinity College Dublin identifies groups most at risk of vitamin D deficiency, including those with dark skin and low intakes. The research highlights the need for better awareness and promotion of adequate vitamin D intake through foods and supplements.
A recent study finds a strong association between hypertensive disorders of pregnancy and an increased risk of coronary artery disease and stroke. The study suggests that hypertensive disorders in pregnancy can be classified as risk factors for cardiovascular disease, highlighting the importance of prenatal care.
A 20-year study by Swansea University researchers found that mothers with a history of substance misuse, smoking, or mental health conditions are at higher risk of having low-birth-weight babies. The study analyzed data from over 693,000 children born in Wales between 1998 and 2018.
A large international study suggests that social and economic disadvantage may explain the higher risk of dementia in women. Women, particularly in low- to lower-middle income countries, have a higher likelihood of developing dementia due to factors such as limited education and occupational opportunities.
Researchers discovered that aircraft noise exposure up to 4 days can cause pro-inflammatory aortic gene expression and increased vascular dysfunction in mice. In humans, noise exposure was linked to elevated C-reactive protein and worse left ventricular function after myocardial infarction.
A study published in eLife has linked infection with the bacterium Fusobacterium nucleatum to an increased risk of cardiovascular disease. The researchers found that individuals with high genetic risk scores for coronary heart disease were at elevated risk for cardiovascular events.
A University of Gothenburg study found that wheelchair users had significantly lower rates of fractures compared to ambulatory older adults. The study, which included 55,442 wheelchair users in Sweden, showed that wheelchair use was associated with a reduced risk of fractures, particularly osteoporotic and hip fractures.
A recent study published in JAMA Network Open found that COVID-19 vaccination significantly reduces the risk of developing new-onset diabetes following an infection. The research suggests a notable benefit of vaccination in protecting against this complication.
Researchers have developed a novel prognostic index to predict survival outcomes in gastric cancer patients. The inflammation-combined prognostic index (ICPI) combines three biomarkers - lymphocyte-to-monocyte ratio, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio - to provide a personalized prognosis for each patient.
A study analyzing 11,167 patients found a 30% lower risk of cardiovascular complications in women compared to men. The researchers argue that other factors contribute to the observed 'male disadvantage' in COVID-19 severity.
A recent clinical study reveals a correlation between low intracranial pressure and impaired patient visibility, especially in the nasal zone. Higher translaminar pressure difference is estimated as a risk factor for normal tension glaucoma development.
Researchers found Paxlovid to be effective in preventing severe COVID-19 and reducing all-cause mortality in adults over 70 years old with mild disease. The study concluded that testing for SARS-CoV-2 and access to Paxlovid are crucial for those at risk of severe infection.
A recent study found that about 1 in 5 people who survived an ischemic stroke had irregular heart rhythms, atrial fibrillation, due to atherosclerosis. The study suggests that these patients are at increased risk of recurrent strokes and highlights the need for continuous cardiac monitoring to detect unsuspected atrial fibrillation.
A recent study by St. Jude Children's Research Hospital found that socioeconomic deprivation and frailty are independently associated with increased late mortality in childhood cancer survivors. The research highlights the importance of policies to improve local environments and access to interventions that may improve health conditions.
A study at Radboud University Medical Center found that pre-hospital troponin measurements can safely identify low-risk patients with chest pain, reducing the need for hospital visits. The results show a small risk of major adverse cardiac events, but also significant cost savings.
A comprehensive registry study found that infants whose mothers used snus during pregnancy were three times more likely to experience sudden infant death. Quitting snus early on lowered the risk, highlighting the need for women to avoid all types of nicotine products during pregnancy.
A Texas A&M University study found that an intervention program increased physical activity in older rural women, leading to improved quality of life and reduced health risks. The Strong Hearts, Healthy Communities 2.0 program was successful in increasing exercise levels at both 12 and 24 weeks.
A study published in eLife found that one in two cancer patients developed long COVID-19 symptoms persisting beyond six months after initial infection. Female cancer patients were more likely to experience long COVID-19 compared to men, and most cases could be managed as outpatients.
Researchers conducted an experiment with nearly 700 people in three countries to gauge the public's perception of relative risk factors. The results suggest a major health-risk public-communications failure in terms of how behaviors compare in relative risk.
Women who followed most aspects of a healthy lifestyle had about half the risk of long COVID compared to those without any healthy lifestyle factors. Maintaining a healthy body weight and adequate sleep were strongly associated with lower risk of long COVID.
Researchers analyzed electronic health record data from over 7.1 million children to identify risk factors associated with a faster decline in kidney function, including disease origin, proteinuria, hypertension, and younger age. The study found that certain attributes are linked to a more rapid decline in kidney function, providing va...
Research suggests that poor oral health may contribute to declines in brain function and cognitive abilities. A recent study analyzed the relationship between oral health and brain health among approximately 40,000 adults and found a potential link between gum disease and white matter hyperintensities.
A new lifestyle-related biomarker, gluconic acid, is associated with high blood pressure and ischemic stroke in Black adults. The study suggests that a blood test measuring metabolites may help determine if diet and exercise are effective in lowering stroke risk.
Adults living in neighborhoods with dense fast food and unhealthy food environments, known as
A recent study found that recurrent stroke risk has declined over the past 20 years, with a greater decrease observed among women compared to men in South Texas. The study analyzed data from nearly 6,000 first-time ischemic stroke survivors and found that lifestyle changes and medication can help prevent recurrent strokes.
A $1.1 million Department of Defense grant supports Augusta University research linking prostate cancer and cardiovascular diseases. Dr. Avirup Guha's research aims to investigate the aging process, exploring the role of nicotinamide adenine dinucleotide in this connection.
A Rutgers researcher has analyzed data from Mexico's Ministry of Health to identify dengue fever hotspots, highlighting areas where severe outbreaks occur. The study found that lower socioeconomic status increases risk of dengue fever and that DENV-2 is the deadliest serotype.
Women who experience five major pregnancy complications face an increased risk of ischemic heart disease up to 46 years after delivery. The study found that all major adverse pregnancy outcomes should be recognized as lifelong risk factors for heart disease.
Researchers discovered a strong association between loneliness, lack of social support, and various dementia risk factors. The study found that modifiable lifestyle factors, such as physical activity and smoking habits, can impact social isolation and ADRD risk.
A UK study using data from over 150,000 hospitalized patients found that immunocompromised individuals had a 44% higher risk of death compared to those with normal immune systems. The gap in mortality rates widened for immunocompromised patients over time, highlighting the need for targeted interventions such as antiviral treatments an...
A new study found that sleep medications increase the risk of dementia in white adults. However, the relationship between sleep medications and dementia risk varies by medication type and socio-economic status. The study suggests that patients with poor sleep should consider alternative solutions before taking medications.
A new study found that women with pre-pregnancy migraine had greater risks of preterm delivery, gestational hypertension, and preeclampsia. Migraine with aura was associated with a higher risk of preeclampsia than without aura.
An international task force led by UNIGE and HUG has developed a preventive protocol to address the growing number of people affected by Alzheimer's disease. The guidelines focus on four pillars: risk assessment, risk communication, risk reduction, and cognitive enhancement.
Characteristics of a patient's neighborhood and hospital where they received treatment are both associated with risk of death after inpatient surgical procedures. Efforts should include improving hospital quality and addressing drivers of neighborhood deprivation to reduce postoperative mortality.
A study found that people with coeliac disease have a 27% increased risk of cardiovascular disease compared to those without the condition. Despite this, they tend to have lower BMI and blood pressure, which are traditional cardiovascular risk factors.
A recent large study suggests that being divorced or single increases the risk of dementia. However, researchers found a surprising result: having children reduced the risk of dementia by 60% among unmarried people.
The number of cardiovascular disease-related deaths in the US rose significantly between 2019 and 2020, with Asian, Black and Hispanic populations most affected. The largest single-year increase since 2015 was seen in CVD deaths among these populations, highlighting structural and societal disparities.
A study published in JAMA Cardiology found that rurality is associated with a higher risk of heart failure among predominantly low-income individuals in the southeastern United States. The inequity highlights the need for targeted primary prevention efforts for rural populations.
A higher rate of sudden infant death syndrome (SIDS) was observed among siblings of children who died of SIDS compared to the general population. Shared genetic and/or environmental factors may contribute to this clustering of SIDS, warranting consideration of family history in clinical assessments.
A study found that nearly one in three public health workers experienced nonphysical workplace violence, including threats and bullying, leading to increased risks of depression, anxiety, PTSD, and suicidal thoughts. The more severe the violence, the greater the impact on mental health.
Insufficient sleep during teenage years is linked to a higher risk of developing multiple sclerosis (MS). Short sleep duration and poor sleep quality are associated with a 40% and 50% increased risk, respectively. The study suggests that sufficient restorative sleep may be an important preventive factor against MS.
A study of women ages 40 to 76 found that family history was the greatest perceived risk factor for breast cancer, with few considering breast density a risk. Comprehensive education is needed to address these misconceptions and reduce breast cancer risk.
A new study led by Mayo Clinic researchers found that women carrying specific genetic changes, such as BRCA1 and BRCA2, have a twofold increased risk of developing contralateral breast cancer. Premenopausal women with these mutations are more likely to develop cancer in both breasts.
A new American Heart Association scientific statement emphasizes the importance of rapid evaluation for TIA, which can lead to full-blown stroke. The statement offers a standardized approach to evaluating people with suspected TIA, including guidance for hospitals in rural areas with limited resources.
A new study found that risk factors for stroke, such as high blood pressure and diabetes, become less significant with age, while others remain unchanged. Researchers discovered varying risks associated with these factors across different age groups, highlighting the need for tailored approaches to managing stroke risk.
A six-year study published in the Journal of the American Heart Association found that reducing overall calorie intake was a stronger determinant of weight change than meal timing. The research suggests that limiting total eating window during the day may not be as effective for controlling weight as previously thought.
A UCSF study suggests people who identify as lesbian, gay, bisexual, transgender, or non-binary may have a higher risk of stroke at a younger age. Non-traditional stroke risks include HIV and syphilis infections.
Pakistan's health challenges have been compounded by natural disasters, including the 2022 floods, which affected over 33 million people. The country is experiencing a slowdown in reducing maternal and child mortality, high fertility rates, and persistent gender disparities.
A new AI tool called Sybil has been developed to predict the risk of lung cancer for individuals with or without a significant smoking history. It uses deep-learning models to analyze low-dose chest computed tomography (LDCT) scans and provides accurate predictions for up to six years.
A new twin study by Karolinska Institutet suggests that the same genes may be behind both cardiometabolic diseases and dementia. The study found that individuals with multiple cardiometabolic conditions had a significantly increased risk of developing dementia.
Researchers found that socially isolated older adults are at higher risk of developing dementia, with technology use shown to lower this risk. The studies suggest that relatively simple efforts to increase social support, such as texting and email use, may reduce the risk of dementia in older adults.
A new study reveals that falls are nearly 50% among older Americans with dementia, emphasizing the importance of addressing environmental and health-related risk factors. Key findings highlight the need for tailored screening and prevention interventions specifically designed for this high-risk population.
A new study led by UCL researchers found small causal effects of childhood maltreatment on internalising and externalising disorders, including depression, anxiety, and psychosis. The study analysed 34 quasi-experimental studies involving over 54,000 people and suggests that preventing eight cases of child maltreatment could prevent on...
A new study found that teenagers who reported feeling optimistic, happy, and loved had better cardiometabolic health outcomes in adulthood. Despite this, racial disparities remained apparent, with Black teens facing increased health risks due to structural racism.
A Canadian study reveals that obesity reprograms immune system cells, making them destructive to the eye as it ages. The research sheds light on the molecular mechanism behind AMD and may lead to tailored treatments in the future.
A new study uses machine learning to predict poor glycemic control in patients with type 2 diabetes, identifying key factors such as prior glucose levels and anti-diabetic medicines. The findings suggest that data routinely collected for diabetes monitoring can reliably identify patients at risk of hyperglycemia.
Research suggests that frequent antibiotic use may heighten the risk of inflammatory bowel disease among older adults. The study found a cumulative risk, with the highest risk observed 1-2 years after antibiotic exposure, particularly for those targeting gut infections.