Research on what raises a person's risk of disease and injury. Covers cardiovascular and aneurysm risk, medication in pregnancy, youth behavior, and suicide risk.
A recent study found that middle-aged individuals with more psychological symptoms are at a higher risk of developing dementia later in life. The study, which included data from over 68,000 Finns, suggests that symptoms of depression, exhaustion, and nervousness can increase the risk of dementia even as early as age 45.
Researchers from prominent institutions discuss hepatocellular carcinoma's pathogenesis, genomic heterogeneity, and targeted therapy options. The review aims to characterize HCC's complexities and develop clinically relevant biomarkers for better management.
Adults with higher serum sodium levels were more likely to develop chronic conditions, show signs of advanced biological aging, and die at a younger age. Optimal hydration may be associated with slower aging and reduced risk of chronic diseases.
A study found nearly one-fourth of breast cancer patients experience reconstructive burnout, characterized by incomplete or abandoned breast reconstruction. Risk factors include radiation therapy, higher body mass index, and tissue expander complications.
A Mediterranean diet has been associated with a reduced risk of adverse pregnancy outcomes. The study found a dose-response relationship between the intake of Mediterranean diet and lower risk of such outcomes.
A new study found that living in neighborhoods with higher opportunity or lower vulnerability can lead to lower mean BMI trajectory and lower risk of obesity in children. The study suggests that investing in neighborhood environments could help mitigate future chronic disease risk, particularly for marginalized communities.
A study of 5,308 participants aged 50-64 found significant correlations between sedentary behavior and low fitness levels. Highly uneven fitness distribution was observed among groups at higher risk, including older adults, foreign-born individuals, and those with poor health and lifestyle habits.
A comprehensive analysis of over 100,000 colorectal cancer cases identified 100 new genetic risk factors strongly linked with the disease. These findings could help clinicians determine who's at highest risk for early detection and potentially identify candidates for preventive treatments.
A Rutgers study found that Hispanic and Latino young men with higher education who were born in the US and speak mostly English at home are more likely to use e-cigarettes. The study analyzed data from 11,275 adult participants and found a high use of e-cigarettes among those under 45 years of age.
A recent University of Galway-led study found that psychosocial stress increases the risk of stroke by 17%, with severe work stress being a significant contributor. The research also revealed that individuals who reported feeling more in control had lower stroke risks.
Researchers at Cleveland Clinic found that elevated levels of phenylacetylglutamine, a byproduct of gut microbiome breakdown, increase heart failure risk and severity. This discovery suggests potential approaches to modify PAG-associated risks through diet and beta blocker use.
Researchers identified several characteristics increasing risk of infection, while others decreased it. Strict adherence to mask-wearing and vitamin D consumption provided significant protection against COVID-19.
A large Finnish study of 5.5 million residents found no evidence of an increased risk of sudden sensorineural hearing loss following COVID-19 vaccination. The study controlled for previous disease and other potential confounding factors, providing reassurance about the safety of COVID-19 vaccines.
A recent study discovered a link between soluble urokinase plasminogen activator receptor (suPAR) and the development of atherosclerosis, a hardening of arteries that affects over a billion people worldwide. SuPAR was found to cause inflammation in blood vessels, leading to cardiovascular events and increasing risk of heart disease.
A new study found that a machine learning-based blood test can accurately predict an individual's entire diet over 19 food groups, outperforming traditional methods. The test, which uses molecular profiling, also identifies who is more likely to develop diabetes and cardiovascular disease based on each food group.
Researchers found that participants who lived alone and reported strong cohesion with their neighbors had a similar risk of death compared to those living with others. Living alone is associated with various poor health outcomes, including depression, cardiovascular disease, dementia, and premature death.
A new study published in Hypertension suggests that lipoprotein(a) cholesterol may affect the relationship between hypertension and cardiovascular disease risk. The study found that people with high levels of lipoprotein(a) and hypertension had a 24% higher risk of cardiovascular disease compared to those without hypertension.
A new study identifies anti-Müllerian hormone (AMH) as a key factor in regulating cholesterol levels during the menopause transition. High AMH levels are associated with lower HDL-C, or good cholesterol, which may indicate cardiovascular risk despite its traditionally protective effects.
A new study found that extreme temperatures are linked to a higher risk of cardiovascular death, particularly heart failure, which was the leading cause of death globally. The research analyzed data from 32 million cardiovascular deaths in 567 cities across 27 countries between 1979 and 2019.
The latest report tracks global trends in cardiovascular health, revealing high blood pressure, high cholesterol, and air pollution as leading causes of cardiovascular disease worldwide. The study estimates that over 80% of cardiovascular disease is preventable.
A unique clinical trial has achieved a remarkable 97% induction survival rate in patients with acute promyelocytic leukemia (APL) by providing a simplified treatment regimen and 24/7 support from APL experts. This collaborative care model, known as EA9131, significantly reduced early deaths and improved overall survival rates.
A large longitudinal study found that weight-loss surgery significantly reduces urinary incontinence episode frequency in adults with severe obesity. After seven years, improvements persist despite some weight regain, offering a durable benefit to patients.
Dr. Urbut's award-winning research explores a new framework to predict coronary artery disease throughout an individual's lifespan, incorporating genomic and nongenomic risk factors. The American Heart Association recognized her innovative work in improving cardiovascular disease prevention.
The study analyzed 23,000 symptomatic individuals in King County, Washington, from June 2020 to July 2022. It found shifts in reported symptoms between SARS-CoV-2 variants and persistent racial and sociodemographic disparities in rhinovirus infection.
A Cedars-Sinai study found that even subtle forms of liver disease directly impact heart health, with elevated FIB-4 scores associated with abnormalities in heart function and vascular dimension. Cardiac MRI scans revealed that nearly 86% of patients had at least one heart abnormality.
A study found that antibodies to common antibiotic gentamicin are associated with an increased risk of progression to type 1 diabetes in children already genetically at risk. The researchers also identified an association between the FUT2 gene and the production of these antibodies, which may be compounding risks for type 1 diabetes.
Global rates of type 2 diabetes in adolescents and young adults have increased significantly between 1990 and 2019, with countries with lower socioeconomic development and women under 30 showing the largest increases. High body mass index is the main contributing factor to this trend.
A large international study found that adopting and maintaining a healthy lifestyle may prevent up to 60% of Crohn's disease and ulcerative colitis cases. The study analyzed data from over 300,000 participants and estimated that a low risk score for inflammatory bowel disease could have prevented a significant proportion of cases if an...
Scientists developed a first model to predict canopy water content during drought and heat waves. The model could enable fire danger forecasting models that include vegetation in their calculations, making it easier to predict the spread of fires.
A study of over one million Medicaid beneficiaries found that more than half experienced significant lapses in coverage, with only 25% continuously enrolled throughout the period. The authors recommend increasing investments to improve long-term health outcomes.
Research highlights importance of long-term screening and healthy lifestyle behaviors in reducing cardiovascular disease risk among young cancer survivors. Factors such as sociodemographic status, income, education, smoking status, and physical activity levels are associated with increased or decreased CVD risk.
A new study published in JAMA Neurology found that using hearing aids can decrease the risk of cognitive decline by 20%. The study, conducted by researchers at NUS Medicine, analyzed data from over 130,000 participants and found a significant association between hearing aid use and reduced cognitive decline. The findings suggest that t...
Researchers investigated neuronal response to excessive iron accumulation associated with age-related neurodegenerative diseases. They identified two genes, CLU and HERPUD1, that responded to aging-related iron accumulation, highlighting potential preventative strategies.
Researchers link loot box purchasing to problem gambling, with 28% of adults who bought loot boxes reporting past-year gambling. The study suggests that loot boxes may prime people to gamble and increase susceptibility to problem gambling.
A study of over 1000 Australian adults found that people with trouble sleeping were more likely to have indicators of poor cardiometabolic health, including inflammatory markers, cholesterol, and body weight. Prioritizing a good night's sleep is crucial for maintaining good health, according to researcher Dr Lisa Matricciani.
A study found that all types of alcoholic beverages increase cancer risk, with higher awareness for liquor than wine or beer. The researchers suggest educating the public about alcohol's link to cancer to prevent excessive use and related health issues.
A lower frequency of adding salt to foods is associated with a reduced risk of heart disease, regardless of lifestyle factors and pre-existing disease. Combining a DASH-style diet with low salt usage further improves heart health.
A long-term study found that eating more than 100 micrograms of vitamin K1 daily reduced the risk of fractures and hospitalizations by 31-49%. Dark leafy vegetables and one-to-two serves of vegetables are recommended for optimal benefits. Vitamin K1 has been shown to enhance cardiovascular health and promote bone health.
Recent studies from the University of Eastern Finland found that lower education levels and previous traumatic brain injuries may increase the risk of frontotemporal dementia (FTD). FTD patients were more likely to have cardiac disease and develop the condition earlier if they had a history of head injury.
Researchers found that individuals with persistent asthma have higher levels of inflammation and artery plaque, which may increase heart attack or stroke risk. The study also highlights the importance of addressing risk factors for cardiovascular disease in people with persistent asthma.
A study published in Oncotarget found that APOE genotype is associated with the presence and severity of cancer treatment-related side effects and symptoms, as well as the response to exercise-based interventions in cancer survivors. ApoE4 carriers showed a lower fall rate after exercise intervention compared to non-carriers.
A recent study found that benzodiazepine treatment for sleep disorders is associated with an increased risk of drug overdose among young people aged 10-29, particularly those with recent opioid prescriptions. This highlights the importance of considering alternative pharmacologic treatments to minimize safety risks.
Research findings suggest that skewed X chromosome inactivation may indicate increased risk of developing chronic diseases, including cardiovascular disease and cancer. XCI-skew is a measure of how many cells in a tissue inactivate the same parental X chromosome.
A study found that South Asian women with genes associated with type 2 diabetes are at a higher risk of developing gestational diabetes during pregnancy. The researchers identified genetic signatures linked with type 2 diabetes risk as strongly and independently associated with gestational diabetes in this population.
Doctors in the UK are urging the government to raise the legal drinking age for kids from 5 to lower their risk of future alcohol-related problems. Preliminary research suggests that introducing children to alcohol may sensitize their brain's addiction centers, and delaying first exposure may reduce problem drinking later on.
A study found that lower levels of HDL cholesterol increased the risk of heart attacks in white but not Black adults. Higher levels of HDL cholesterol did not provide protective benefits for either group. The research tested long-held assumptions about the role of HDL in cardiovascular health.
Research published in General Psychiatry finds a significant causal relationship between diastolic blood pressure and neuroticism, while systolic blood pressure has no association. Controlling high diastolic blood pressure may help reduce neurotic behaviors, anxiety, and cardiovascular diseases.
A large observational study found that women diagnosed with benign breast disease through screening are at a higher risk of developing breast cancer in the long term. The risk persisted for at least two decades and was found to be significantly higher among women with benign breast disease compared to those without.
Researchers identified key risk factors for intimate partner violence in pregnant women, including head injuries, multiple contusions, and certain injury patterns. The study highlights the importance of screening for IPV in pregnant trauma patients to prevent poor outcomes such as premature birth and low birth weight.
A new study found that people with a higher sense of purpose in life have a lower risk of death from any cause, regardless of race or gender. The association was strongest among women, who may benefit more from the health-protective effects of purpose.
A new model predicts individual breast cancer risk based on ten known risk factors, allowing for tailored screening strategies. The study found that the risk of developing breast cancer ranges from 0.22% to 7.43%, with some factors, such as exercise, having a greater impact than previously thought.
A new calculator will assess an individual's risk and benefit of taking bisphosphonates for osteoporosis, considering factors such as fracture history and comorbid conditions. The calculator aims to provide personalized guidance on whether a drug holiday is beneficial or not.
Researchers found that higher levels of polybrominated diphenyl ethers (PBDEs) in pregnant women were associated with increased anxiety scores in their children at age 12. The study suggests that exposure to flame retardants during early brain development may be a risk factor for developing anxiety symptoms in early adolescence.
The American Heart Association statement highlights telehealth's benefits in managing cardiovascular disease, including cost-effectiveness and improved rehabilitation. However, challenges like access to broadband internet and privacy security concerns hinder widespread adoption.
A large study found that children who experienced adversity, including serious family illness or death, poverty, neglect, or dysfunctional relationships, are at increased risk of developing cardiovascular disease in early adulthood. The study, published in the European Heart Journal, followed nearly 1.3 million children and found a 60%...
A randomized controlled trial found that both total ankle replacement and ankle fusion improve quality of life and have similar clinical scores in patients with end-stage ankle osteoarthritis. However, TAR is associated with greater wound-healing complications and nerve injuries, while AF is linked to more blood clots and nonunion of t...
A decades-long effort to lower the US stillbirth rate has stalled, with no progress made in reducing disparities between Black and White women. Despite advances in prenatal care and maternal health, excess stillbirths experienced by Black women have remained unchanged since the mid-2000s.
A study of over 111,000 veterans found that prescription of anti-SARS-CoV-2 pharmacotherapies was underused, particularly among those with risk factors for severe COVID-19 and minority groups. Veterans with limited outpatient access to these treatments were also less likely to receive them.
A new study of 200,000 patients found that those who smoke cigarettes and drink heavily are more likely to experience post-surgical complications. However, talking to a health coach about drinking-related risks before surgery can help patients cut their alcohol use in half and reduce the likelihood of surgical issues.
Researchers at Michigan Medicine found a strong association between lower grip strength and accelerated biological aging in middle-aged and older adults. This study provides evidence that maintaining muscle strength across the lifespan may help protect against age-related diseases.