Research on what raises a person's risk of disease and injury. Covers cardiovascular and aneurysm risk, medication in pregnancy, youth behavior, and suicide risk.
A new automated screening tool can accurately identify patients at high risk of developing progressive scarring of the lungs, a condition called idiopathic pulmonary fibrosis (IPF). The tool uses machine-learning algorithms to analyze patient electronic health records and detects IPF risk automatically.
A study from UniSA researchers found associations between metabolic profiles and adverse brain findings, including lower hippocampal and grey matter volumes. People with metabolic profiles linked to obesity were more likely to have higher accumulation of iron in the brain.
A Brazilian study of 26,616 tree falls in São Paulo found that building height and neighborhood age are key factors influencing the risk of tree failure. Sidewalk width and tree height were also found to be significant variables. The research provides valuable insights for urban planning and tree management in the city.
A new study finds that high blood pressure speeds up cognitive decline in both Hispanic and non-Hispanic white adults. However, differences in blood pressure control do not fully explain the higher risk of dementia in Hispanic adults.
A recent study found that 38% of people with cardiovascular disease were food insecure in 2017-2018, more than doubling from two decades earlier. Food insecurity exacerbates existing racial and ethnic health disparities and can lead to increased risk for cardiometabolic risk factors.
A cohort study of nearly 200,000 people found that intentional weight loss reduces the risk of type 2 diabetes for those who are overweight or obese. However, for lean individuals, weight loss attempts are associated with longer-term weight gain and higher risks of type 2 diabetes.
Research found a 74% higher risk of hypertensive disorders in pregnancy among women who received frozen embryo transfers compared to those with fresh embryo transfers or natural conception. The study suggests that IVF treatment factors may be involved, but more research is needed to identify the specific risks.
New research shows that COVID-19 infections can lead to a range of neurological complications in the first year after infection, including strokes, cognitive decline, depression, anxiety, and migraine headaches. The study analyzed over 14 million medical records and found that COVID-19 survivors were at increased risk of developing the...
A recent study reveals that anthropogenic air pollution contributes significantly to poor air quality and climate change in the Middle East. The research found that hazardous fine particulate matter from human activities accounts for around 53% of aerosol visible optical depth, posing a significant health risk.
Women with a history of gestational diabetes are at substantially higher risk of cardiovascular and cerebrovascular diseases, including coronary artery disease, heart attack, and stroke. Continuous monitoring is crucial to mitigate these risks.
A study published in The BMJ found that adopting a healthy lifestyle can reduce the risk of type 2 diabetes by up to 90% in women with a history of gestational diabetes. Women who adhered to five key lifestyle factors had a significantly lower risk of developing type 2 diabetes, regardless of their weight or genetic risk.
Research found that people with HIV who also have untreated hepatitis C virus have a higher risk of heart attack as they age. The study analyzed health data from 23,361 people with HIV and found that those co-infected with hepatitis C had a significantly increased risk of heart attack compared to those with HIV alone.
Women who underwent a hysterectomy before age 45 have a 52% increased risk of developing incident type 2 diabetes, according to a study of over 83,000 French women. The risk remains even if ovaries are not removed and is unrelated to diet and physical activity.
A mutation in the SHMOOSE protein is associated with a 20-50% higher risk of Alzheimer's disease across four cohorts. The researchers suggest that targeting SHMOOSE may prove beneficial in neurodegenerative and other diseases of aging.
A Brazilian study analyzed risk factors for heart attacks and found that high blood sugar had the most significant impact on mortality. Reducing smoking prevented most deaths from cardiovascular disease, while lowering diabetes incidence could have saved up to 5,000 lives over a decade.
The study found that nearly 9% of Americans aged 12 or older experienced a past-year major depressive episode. Depression was particularly common among adolescents (16.9%) and young adults (17%), with increased prevalence among various demographic groups, yet low help-seeking rates remained consistently low.
A study found that many people with health insurance still struggle with medical debt, which can lead to evictions, foreclosures, and food insecurity. The analysis of survey data suggests a significant association between medical debt and worsening social determinants of health.
A new genomic test can predict a patient's risk of developing severe COVID-19, according to research from the University of Virginia Health System. The test, called CovGENE, analyzes genes expressed in a person's blood to determine if they may experience a severe disease course with increased risk of death.
Researchers found associations between financial hardship, food insecurity, housing instability, and transportation difficulties with increased mortality risk among adults with new cancer diagnosis. The study highlights the importance of addressing social determinants of health for improving patient outcomes.
Two UC Riverside-led studies found 30% of Native Hawaiian/Pacific Islanders diagnosed with COVID-19 and nearly 1 in 5 reported a close family member's death due to the virus. The research also highlighted high levels of substance use, depression, anxiety, and unmet treatment need among NH/PIs during COVID-19.
The September issue of CHEST journal features 40 articles on clinically relevant topics, including disparities in rural populations with idiopathic pulmonary fibrosis. The journal also offers complementary web and multimedia activities to expand its reach.
Researchers found that 12% of cancer survivors lived in poverty, experiencing negative effects on physical and mental health. Financial burden of cancer care persists years after diagnosis, leading to poor health outcomes and increased mortality.
A new study published in PLOS Medicine found that people with hospital-treated infections in early- and mid-life had a higher risk of developing Alzheimer's disease (AD) and Parkinson's disease (PD). The research analyzed data on over 291,000 cases and matched controls to identify the association between infections and neurodegenerativ...
The Regional Transition Navigator program aims to connect youth and young adults aged 14-25 with needed resources, emphasizing those at risk of homelessness, human trafficking or substance use disorders. The program's long-term goal is to teach problem-solving skills and provide support for a healthier transition into adulthood.
A UC San Diego study found that cancer patients experiencing housing instability had a significantly increased risk of mortality. The research suggests that integrating health and social care can improve patient outcomes by identifying and addressing underlying social risk factors.
A New York City-based study analyzed over 600,000 household contacts to determine the risks of acquiring SARS-CoV-2 infection after exposure. The research found specific risk factors associated with a higher likelihood of developing COVID-19
A new study published in the Journal of the American Heart Association found that individuals with autoimmune diseases are at a higher risk of complications after a heart attack. The research emphasizes the importance of controlling cardiovascular disease risk factors and developing personalized treatment plans for this population.
Researchers are developing a serious game, Simulation for Environmental Exposure Education (SE3), to improve middle-school age youth's environmental health literacy. The game focuses on exposure to environmental toxins in the home and aims to increase knowledge and understanding of risks, as well as promote action to reduce them.
New research estimates the overall disease burden of genetic risk factors on healthy life years lost, prioritizing interventions using genetic information. The study found that common genetic variants for cardio-vascular diseases and Alzheimer’s disease have a substantial population-level impact.
Researchers used data from over 400,000 individuals to model genetic and environmental factors influencing common neuropsychiatric disorders. Gene-environment interactions accounted for a significant proportion of variability in some disorders, while others showed more substantial contributions.
Researchers found that men who received positive fortune telling outcomes were more likely to take financial risks, while the effect was weaker in women. This study suggests that superstition can influence behavior, even among those who claim not to be superstitious.
A study published in Neurology suggests that getting an annual flu shot may be associated with a lower risk of stroke. Researchers found that those who received the flu shot were 12% less likely to have a stroke than those who did not, after adjusting for other factors.
A survey study of a large professional society meeting during the Omicron surge found low COVID-19 positivity rates among both in-person and virtual attendees. The study suggests that cautious strategies to mitigate transmission were effective, with no greater risk associated with in-person attendance.
Researchers studied over 500,000 children born between 1987 and 2010, finding no causal link between maternal infection and autism. However, they did find a weaker link for intellectual disability, suggesting other factors may be at play.
Researchers at Harvard T.H. Chan School of Public Health found that psychological distress before COVID-19 infection was associated with a 32%-46% increased risk of developing long COVID and 15%–51% greater daily life impairment due to long COVID.
A study published in the Journal of Bone and Mineral Research found that adults with osteoporosis are at a higher risk of developing cardiovascular disease. The research identified several key risk factors, including older age, smoking, and use of anti-hypertensive medications.
A large study found that obstructive sleep apnea is independently associated with an increased risk of cancer. Patients with more severe OSA were also at a greater risk of developing blood clots. Additionally, a second study linked OSA to a decline in mental processing powers, particularly in the elderly.
A study by researchers at Washington University School of Medicine found that low testosterone levels are an independent risk factor for COVID-19 hospitalization in men. Men with chronically low testosterone who developed COVID-19 were 2.4 times more likely to require hospitalization than those with normal testosterone levels.
Research suggests that arterial stiffness increases blood pressure in adolescents due to insulin resistance, not body fat. Healthy lifestyle choices like exercise and a balanced diet may help lower blood pressure in this age group.
A new study finds that COVID-19 orphanhood is significantly higher in poorer countries due to pre-existing health and vaccine coverage inequity. The risk is driven by factors like poverty prevalence, lower GDP per capita, and non-communicable diseases.
A new study published in the Journal of the American Heart Association found that low physical function after age 65 is associated with a greater risk of developing heart attack, heart failure, and stroke. The study used the Short Physical Performance Battery (SPPB) test to assess physical function in 5,570 adults over 75 years old.
A study found that genetic testing before pregnancy can detect the risk of severe developmental disorders in 44% of cases if parents are related. However, non-hereditary mutations play a larger role in children of non-consanguineous couples, and many genes remain undetected.
A 21% relative risk reduction in reported high-risk HIV behavior was found for single mothers with a State-level Earned Income Tax Credit (SEITC) of 10% or above the Federal EITC. A 10 percentage-point increase in SEITC was also linked to a 38% relative reduction in high-risk behavior.
A study published in Circulation found that moderate or vigorous physical activity can lower the risk of developing heart failure. The research, which analyzed data from over 94,000 adults, suggests that increasing physical activity duration and intensity may provide greater protection against heart failure.
A study of 22 million patients found that those with autoimmune disorders have a substantially higher risk of developing cardiovascular disease. The excess risk is similar to that of type 2 diabetes and affects the entire cardiovascular disease spectrum.
Research finds that a single dose of alcohol permanently changes brain structure and function, leading to increased risk of addiction. The study used fruit flies and mice models to show that ethanol-induced changes in mitochondrial dynamics and synapse balance contribute to long-lasting behavioral changes.
Research finds that liver transplant recipients with a BMI of 30 or higher and those who drank heavily have a high risk of needing a second surgery within 48 hours. Coagulopathy, or decreased blood clotting, is also linked to this risk. The study aims to reduce the number of return-to-operating-room cases by mitigating these factors.
Public health researchers developed a global vaccine risk index (VRI) to predict vaccine coverage lapses worldwide. The VRI considers factors like measles incidence, vaccine confidence, climate change, education, and income, revealing countries at high risk of disease outbreaks.
A recent study published in the Journal of Aging and Physical Activity found that higher levels of light physical activity and moderate-to-vigorous physical activity were associated with lower risk of death. In contrast, higher sedentary time was linked to increased mortality risk, regardless of genetic predisposition for longevity.
A new study identified five socio-economic and health risk profiles among mothers of young children that may lead to food insecurity. The study found that these risk profiles can help pediatricians identify families at risk for food insecurity, who may be reluctant to disclose their struggles due to fear of child removal.
A recent study published in JAMA found that despite overall improvements in cholesterol levels since 2008, sex, racial, and ethnic disparities persist in lipid control. The research team analyzed data from over 33,000 US adults and discovered significant variations in trends by race and ethnicity.
Research on mice reveals that older fathers produce pups with reduced vocal complexity and lower body weights, similar to children with neurodevelopmental disorders. The study provides evidence for the risk factor of advanced paternal age on infant development.
Research suggests that regular physical activity is linked to a lower risk of COVID-19 infection and severity, including hospital admission and death. Adults who engaged in at least 500 MET minutes per week had a significant reduction in risk, with the highest protective effect observed at this threshold.
Researchers at Michigan Medicine have discovered a molecular mechanism that drives the disease-causing effects of the most common genetic risk factor for lupus. The study suggests that targeting this new pathway could lead to the development of safe and effective treatments for SLE, an autoimmune disease that affects millions worldwide.
A systematic review and meta-analysis of 26 studies involving over 100,000 women found that mothers with a family history of psychiatric disorders are at almost twice the risk of developing postpartum depression. The findings suggest that family history may be a significant risk factor for postpartum depression.
Researchers at Florida International University discover that DDT causes an increase in toxic amyloid beta, a characteristic of Alzheimer's disease. By blocking sodium channels with tetrodotoxin, the production of toxic amyloid-beta species is prevented.
A study by CNIC scientists has identified a key role for the MKK3/6–p38γ/δ signaling pathway in cardiac hypertrophy. Inhibition of p38α promotes an unexpected activation of the other branch of the pathway, consisting of the proteins MKK3, p38γ, and p38δ. This activation induces another key pathway in cardiac hypertrophy, the mTOR pathway.
A West Virginia University study explores the link between pregnancy, sedentary behavior, and cardiovascular disease risk in women. The research aims to investigate whether physical activity can reduce or eliminate this accelerated risk development in women.
A new gene variant, MFGE8, has been discovered that protects against coronary heart disease, with carriers experiencing a one-fifth lower risk. The variant is located in the MFGE8 gene and inhibits the function of lactadherin protein, which affects arterial stiffness.
A study of over 1.2 million people in 76 low- and middle-income countries found that hypertension prevalence is high among the least educated and poorest individuals, despite common assumptions. The findings highlight the need for targeted interventions to lower blood pressure in these regions.