Researchers found that male rats with normal testosterone levels had stronger ACLs than those without it. The study suggests a link between testosterone and ACL injuries, which could lead to new techniques for identifying athletes at high risk of injury.
A six-month open-label study found that treatment with a 2% testosterone solution improved low sex drive and low energy symptoms in men with hypogonadism. The safety profile was consistent with previous trials, indicating that long-term treatment is safe and effective.
Researchers found that a specific gene mutation linked to impulsive behavior also protects carriers from obesity and insulin resistance, which are risk factors for type 2 diabetes. The study suggests that lower testosterone levels in these individuals actually increase insulin sensitivity.
A large placebo-controlled study found that testosterone therapy significantly improved sexual interest and function in older men with low libido and low testosterone levels. The study, the largest of its kind, showed consistent improvement in most types of sexual activity among those who received testosterone therapy.
A consensus conference of international experts found testosterone therapy to be effective in treating low testosterone levels, regardless of underlying origin. The panel rejected concerns about increased cardiovascular risk, stating that the evidence suggests potential cardio-protective effects.
A systematic review of 40 studies found a weak correlation between signs, symptoms, and testosterone levels in ageing men. The authors suggest that it is difficult to extrapolate the diagnosis of pathologic hypogonadism from younger men to older men with age-related testosterone declines.
Researchers found that the testes of larger, more aggressive dark-eyed juncos produced more testosterone, leading to flashier plumage and other traits influenced by testosterone. The study challenges the prevailing theory that hormonally regulated trait differences are controlled largely by the brain.
A large analysis of medical records in Sweden found that men taking testosterone therapy for over a year had no increased risk of prostate cancer and, in fact, had their risk reduced by 50 percent. The study's findings suggest that balancing testosterone levels within a normal range may be key to protecting against aggressive disease.
A recent study found that testosterone therapy improved erectile function and intercourse satisfaction in men with severe hypogonadism, a condition often associated with type 2 diabetes. The study suggests that trials of testosterone therapy should last at least 6 months for optimal results.
A new study from Wake Forest University found that testosterone influences the evolution of a waving display in male Bornean rock frogs. The research revealed that testosterone increases foot-flagging behavior and changes how hormones act on leg muscles, similar to the change seen in vocal croaks.
Researchers have identified how low testosterone raises diabetes risk by impairing insulin regulation in the pancreas. Testosterone triggers key signaling mechanisms that produce insulin, and its absence leads to glucose intolerance.
Researchers at Johns Hopkins Bloomberg School of Public Health have discovered a way to encourage adult stem cells to proliferate and differentiate into testosterone-producing cells. The findings could lead to the development of transplantable cells that can produce testosterone, avoiding side effects associated with current treatments.
A large-scale population-based study found that older men using testosterone therapy had lower rates of hospital readmissions compared to non-users. The study, published in Mayo Clinic Proceedings, analyzed data from over 6,000 men and showed a 9.8% rate of 30-day hospital readmissions among testosterone users versus 13% for non-users.
A new study from Intermountain Medical Center Heart Institute shows that testosterone supplementation reduced major adverse cardiovascular events in elderly men with low testosterone levels and pre-existing coronary artery disease. The study found that patients receiving testosterone therapy had a lower risk of heart attacks, strokes, ...
In a clinical trial of 100 obese men, researchers found that adding testosterone treatment to calorie restriction resulted in increased fat loss and preserved muscle mass. The study suggests that testosterone treatment may be a useful adjunct to weight loss in obese men with low testosterone levels.
Researchers found testosterone treatment improved all aspects of sexual function, including sexual activity and desire, in men with low testosterone levels. However, the study did not confirm earlier concerns about cardiovascular safety.
A large nationwide study found that testosterone treatment improved sexual desire and function, as well as mood and depressive symptoms, in men with low testosterone levels. The treatment also showed no significant increase in cardiovascular issues.
Researchers found testosterone treatment benefits older men with low testosterone levels, improving sexual function, walking ability, and mood. The treatment also had no significant impact on energy but reduced depressive symptoms.
The Testosterone Trials found that testosterone treatment increased blood testosterone levels and improved all aspects of sexual function, including desire and ability to get an erection. The treatment also showed benefits in mood and depressive symptoms, but not energy or distance walked.
Researchers at Yale University found that testosterone therapy significantly improved sexual function, including sexual activity, desire, and erectile function, in men over age 65. Additionally, testosterone treatment showed modest benefits in terms of improved mood and fewer depressive symptoms.
The TTrials study reveals that testosterone treatment improves sexual function, including increased sexual activity and desire, as well as walking ability and mood. However, the treatment did not significantly improve energy or cognitive function, and its risks remain unclear.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism suggests that high testosterone levels may increase the risk of developing uterine fibroids in midlife women. Women with both high testosterone and estrogen levels faced a greater risk of developing fibroids.
Researchers found that men use cardinal directions more efficiently and the hippocampus less than women, while women rely on local memory. Administering testosterone improved women's navigation skills, but not their performance.
Research found that young men with greater interest in babies showed smaller increases in testosterone in response to sexually explicit stimuli, indicating a 'slow' life-history strategy. In contrast, men who didn't like babies as much were more physiologically aroused by novel sexual stimuli.
A study of medical records found that men taking androgen deprivation therapy for prostate cancer were almost twice as likely to be diagnosed with Alzheimer's disease as those who didn't undergo the therapy. The longer duration of ADT, the greater the risk of Alzheimer's disease.
A study by University at Buffalo researchers found that testosterone replacement therapy increases insulin sensitivity and reduces body fat in Type 2 diabetic men. Testosterone treatment also improved muscle mass and expression of genes that mediate insulin signaling.
The European Menopause and Andropause Society (EMAS) has published a position statement on testosterone replacement therapy in the aging male, highlighting the importance of lifestyle modifications before considering TRT. The statement emphasizes the need for careful risk versus benefit estimation and individual evaluation of co-morbid...
A new study by University of Notre Dame anthropologists found that aging U.S. men with emotionally supportive relationships have lower testosterone levels compared to their less supportive counterparts. This connection may help explain the link between social support and improved overall health.
A new study of 1,472 healthy men found that testosterone supplementation did not increase the risk of heart attack, stroke, or death. Testosterone therapy was shown to reduce these risks compared to non-supplemented individuals.
Researchers at Karolinska Institutet identified a hormonal mechanism explaining why women with PCOS are more likely to develop mental health issues. The study found that excessive testosterone exposure during fetal development can lead to anxiety-like behavior in both male and female offspring.
A new University of Michigan study found that low testosterone in fathers is associated with less sensitive parenting. Men who are more empathetic and have a loving relationship with their infant's mother exhibit nurturing fathering behavior. This can impact young children's social, emotional, and cognitive development positively.
Researchers have discovered that a drug restoring natural testosterone production has no negative effect on sperm count, unlike traditional testosterone replacement therapy. This approach could change the way men are treated for low testosterone, potentially preserving fertility.
A new guideline from the Canadian Men's Health Foundation provides a roadmap for diagnosing and treating testosterone deficiency in men. Key recommendations include conducting thorough patient histories, measuring total testosterone levels, and assessing patient response to treatment.
A new study shows that sleeve gastrectomy can increase testosterone levels in obese men by 43% over a 12-month period, while also lowering BMI and reducing cardiac risk factors. This procedure has been shown to improve sexual quality of life and reduce the risk of sarcopenia.
A new population-based study found no association between testosterone therapy and aggressive prostate cancer risk over a five-year period. The study analyzed data from Medicare linked records and included 52,579 men diagnosed with prostate cancer between 2001-2006.
A study by Dr. Raffaella Leoci and colleagues found that a specific ultrasound treatment regime can permanently sterilize male dogs without affecting testosterone levels. The method involves three applications of ultrasound at 1 MHz, lasting five minutes, and resulted in significant reduction in testicular volume and degeneration.
A unique study found that testosterone therapy induces structural changes in areas of the brain involved in verbal fluency in female-to-male transsexuals. This may suggest that sex hormones play a substantial role in shaping human brain structure, beyond early developmental phases.
A 3-year testosterone supplementation study found no significant association between treatment and atherosclerosis progression. The trial also showed no improvements in sexual function or quality of life, despite increased hematocrit and prostate-specific antigen levels.
A three-year clinical trial found no link between testosterone administration and atherosclerosis progression, sexual function, or quality of life in older men. The study suggests that testosterone should not be used indiscriminately by men, as it may not provide benefits for these outcomes.
A study of over 83,000 veterans found that restoring normal testosterone levels through gels, patches, or injections reduced the risk of heart attack, stroke, and death. Men who achieved normal levels saw significant benefits in cardiovascular health, while those who did not attained normal levels did not experience similar reductions.
Researchers found that candidates with lower-pitched voices generally win elections, particularly against female opponents. However, the preference for leaders with lower voices also correlates with perceptions of strength and competence.
Research suggests that normalization of testosterone levels through TRT is associated with lower mortality and fewer cardiovascular events in men without a previous history of myocardial infarction or stroke. The study used a large cohort of male veterans to establish this link, highlighting the potential benefits of adequate TRT dose
A large-scale study of over 30,000 men found no link between testosterone therapy and venous thromboembolism. The study suggests that testosterone therapy is not associated with an increased risk of blood clots in veins, which is a common cardiovascular illness.
The International Society for Sexual Medicine recommends a clinical and biochemical syndrome definition for testosterone deficiency, characterized by low testosterone levels and symptoms. The new guidelines provide evidence-based guidance on testing, lifestyle modifications, and treatment options for men with testosterone deficiency.
A new study found that testosterone replacement therapy did not improve sexual function in men with ejaculatory disorders and low testosterone levels. Despite a small increase in testosterone levels, the treatment did not show significant benefits in ejaculate volume or orgasmic function.
A study suggests that cortisol and testosterone levels in traders can lead to increased risk-taking behavior, potentially destabilizing financial markets. Researchers found that artificially increasing hormone levels shifted investment towards riskier assets.
A study of 200 adult men found that those with borderline testosterone levels had a 56% rate of depression and depressive symptoms, highlighting the importance of screening for mental health in this population. The researchers also identified high rates of obesity and low physical activity as contributing factors.
Researchers found that finasteride treatment led to a marked decline in erectile function and testosterone levels, while tamsulosin therapy showed no adverse effects. The study highlights the need for careful consideration of sexual side effects when treating benign prostate enlargement with 5α reductase inhibitors.
Research suggests that prolonged paracetamol use during pregnancy may reduce testosterone production in unborn baby boys, potentially linked to reproductive health problems later in life. The study found a 45% decrease in testosterone levels after seven days of exposure.
Researchers found that female lemurs have higher testosterone levels in some species, leading to dominant behavior and challenging traditional gender roles. This discovery suggests that hormones play a role in female dominance in these animals.
A recent study found that health food stores across the US recommended and sold over-the-counter dietary supplements to minors, despite "adults-only" labels. The American Academy of Pediatrics warns against using such products for males and females under 18.
Researchers discovered that birds with complex courtship displays have muscles sensitive to testosterone, enabling them to perform impressive acrobatics. This groundbreaking study sheds light on how hormones control social behavior in birds, paving the way for further research into the evolution of bird brawn.
The study found a strong correlation between men's endurance running ability and prenatal testosterone exposure, with good runners having greater reproductive potential. Researchers suggest that female selection for athletic endurance in males may have been driven by the importance of persistence hunting in hunter-gatherer societies.
A study published in The FASEB Journal found that the androgen receptor confers protection against diet-induced atherosclerosis, obesity, and dyslipidemia in female mice. Researchers discovered this association by comparing female mice with and without the androgen receptor.
The marketing, prescribing, and selling of testosterone and growth hormone as solutions for aging-associated problems is considered disease mongering. The FDA has recently acknowledged that these treatments are not indicated for age-related decline in serum testosterone, with potential risks outweighing benefits.
A study by UC Santa Barbara anthropologists found that Tsimane men's oxytocin levels increase when they come home to their families after a day of hunting, positively correlating with changes in testosterone. This hormonal response may serve as a balance between social bonding and competition.
A new study from Australia found that decreased sexual activity and desire in older men may be a cause, not an effect, of low circulating testosterone levels. Over two years, men with declining serum testosterone were more likely to experience a significant decrease in their sexual activity.
A new testosterone nasal gel has been shown to effectively raise men's low testosterone levels to normal, with minimal side effects. The medication was found to be most effective when administered three times a day, resulting in improved erectile function and mood.
A study by Harvard Medical School found that higher testosterone levels and lower estrogen levels in men worsen cardiovascular risk factors such as insulin resistance and muscle fat. This discovery may help explain why men have a higher risk of heart disease compared to premenopausal women.
A study of 200 adult men with borderline testosterone levels found that 56% had significant depressive symptoms, highlighting the need for clinicians to manage comorbidities like depression and obesity in this population. The researchers also noted a high prevalence of overweight, obesity, and physical inactivity among participants.