The Endocrine Society has released updated guidelines for testosterone prescribing practices, recommending reserving therapy for men with well-documented hypogonadism. The guidelines also suggest individualizing treatment decisions for older men and avoiding routine testing for healthy men.
A recent study published in Endocrine Practice found that only a quarter of transgender women could lower their testosterone levels within the female range using spironolactone and estrogen therapy. The researchers identified four groups with varying degrees of testosterone suppression, highlighting the need for further studies to unde...
A study published in Computers in Human Behavior found no significant changes in testosterone levels among UNLV's esports players during gameplay. The research suggests that familiar environments and competition may not elicit the same hormonal responses as unfamiliar situations and large audiences.
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Researchers identified a guardian molecule triggered by testosterone that protects males from disease. Treatment with the molecule eliminated symptoms in female mice, offering hope for new MS therapies.
Researchers found that women with PCOS have less diverse gut bacteria compared to those without the condition. Elevated testosterone levels in PCOS may contribute to these changes, suggesting a potential link between the microbiome and the development of PCOS.
A new study found that increasing testosterone levels in young male traders causes them to bid up prices, leading to price bubbles and crashes. The researchers suggest limiting the risk taken by these traders to prevent biased decision-making.
Researchers found that winning a competition makes people more willing to pay for luxury items and assign greater value to them. Contrary to expectations, testosterone levels were unaffected by winning or losing.
A new study found that fathers' testosterone levels after childbirth are linked to their own and partners' depressive symptoms. Low testosterone levels were associated with fewer symptoms of depression in women, while high levels led to more stress and relationship aggression.
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Golden-collared manakin males use cleanliness to attract mates and exhibit complex courtship displays. In contrast, females show no motivation to clean their male counterparts' displays, suggesting hormonal influence is specific to males.
A new study by researchers at the Ivey Business School found that elevated testosterone levels in male traders increased bid prices and asset price bubbles, leading to market instability. The experiment showed that testosterone drove changes in market dynamics by increasing bidding, selling prices, and volume.
A new study shows significant improvement in sexual and urinary function as well as quality of life for hypogonadal men undergoing long-term testosterone replacement therapy. Testosterone therapy is found to increase bladder emptying, improve erectile/sexual health and overall quality of life.
Research reveals that testosterone plays a crucial role in regulating canary birdsong by targeting specific brain regions involved in singing. The nucleus of the arcopallium (RA) regulates song unit production, while HVC influences syntactical features such as syllable repetition and trill duration.
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Researchers found that testosterone reduces the effectiveness of anti-inflammatory drugs in men, increasing prostaglandins and promoting inflammatory reactions. This discovery supports the need for gender-specific medicine, suggesting that treatment may require separate 'his' and 'hers' medicine cabinets.
A recent study on California mice found that surges of testosterone before and after aggressive encounters lead to future wins. Winning experiences change the brain's response to testosterone, fueling competitiveness and confidence.
Researchers at Cold Spring Harbor Laboratory have identified the specific hormone receptors and brain regions responsible for masculinization in mice. The study found that estrogen receptor alpha is essential in inhibitory neurons for male sexual and aggressive behaviors to emerge, while deleting it had no impact on excitatory neurons.
A new study highlights the need to improve testosterone prescribing practices in the VA, with variations found in age, experience, specialty, and region. Providers under 40 were more likely to prescribe testosterone, while those over 60 were less likely.
Research reveals that naturally produced testosterone in some elite female athletes gives them a competitive advantage in athletics events that depend on stamina and visuospatial abilities. Women with high levels of free testosterone performed significantly better in certain events, such as the 400m sprint and hammer throw.
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A new study from the University of Copenhagen found that paracetamol can reduce sex drive and aggressive behavior in mice by inhibiting testosterone development. The research suggests that pregnant women should exercise caution when taking paracetamol, as it may have unintended effects on their children's masculinity.
A study by Australian researchers has found that testosterone suppresses the production of immune cells that trigger allergic asthma. The finding may lead to new, targeted treatments for the disease. Women are two times more likely to develop asthma than men after puberty due to testosterone's protective effects.
A study found that testosterone administration impairs cognitive reflection in men, making them more likely to rely on their gut instincts. The researchers tested the hypothesis that higher levels of testosterone increase the tendency to make intuitive judgments and reduce self-reflection.
High testosterone levels are associated with competitive, status-seeking social behaviors, while low testosterone is linked to cooperative behaviors. Researchers found that mixed populations with a balance of high and low-testosterone individuals are more likely to form effective social hierarchies.
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The study found that E4 lowered testosterone levels in healthy male volunteers, with decreasing total and free testosterone, FSH, and estradiol levels. The hormone was well-tolerated, with only libido decrease and nipple tenderness reported.
Direct-to-consumer ads for low-testosterone treatments increase prescriptions but may not improve men's health, according to UC Davis physician Richard Kravitz. The rise in hormone-replacement therapies has led to unnecessary treatments and potential cardiovascular risks.
A study found a strong association between TV advertising for testosterone therapies and increased testing, new prescriptions, and treatment initiation. The increase in testosterone use was particularly notable among men without clear indications for treatment.
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Researchers found that soldiers who exhibited less change in both testosterone and cortisol levels in response to stress were more likely to later show PTSD symptoms. The study suggests future research could investigate preventative interventions targeting those with at-risk hormone profiles.
Research by Ben-Gurion University finds that men's psychological momentum, driven by testosterone increases after success, leads to exaggerated risk-taking in financial markets. This can create price bubbles. The study suggests that increasing women in financial markets may help stabilize these markets.
Men treated with testosterone replacement therapy had a 33% lower risk of heart attacks and strokes compared to those who didn't receive hormone therapy. Androgen deficiency is characterized by low testosterone levels, which can cause symptoms like erectile dysfunction and hot flashes.
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Research found testosterone treatment improved bone density and anemia for men over 65 with low testosterone, while also increasing plaque buildup in coronary arteries. However, cognitive function remained unchanged.
A new study published in JAMA suggests that testosterone treatments may increase the risk of heart disease in older men. The study found a significant increase in arterial plaque among men aged 65 and older who received testosterone replacement therapy for a year, with a 20% rise in total coronary and noncalcified plaque volumes.
A study published in JAMA and JAMA Internal Medicine found that testosterone treatment improved bone density and anemia, but not cognitive function, in older men with low testosterone. However, it also increased plaque buildup in coronary arteries, raising concerns about cardiac risk.
A new study published in JAMA and J AMA Internal Medicine found that testosterone therapy improved bone density and strength, as well as reduced anemia in older men with low testosterone levels. However, the therapy had no impact on cognitive function and may worsen plaque in coronary arteries.
Studies published in JAMA and JAMA Internal Medicine found that testosterone treatment was associated with improved bone density and anemia in men with low testosterone. However, the studies also found no significant association between testosterone treatment and improved cognitive function or reduced risk of cardiovascular problems.
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A new study found that long-term testosterone therapy improves vigor and vitality, while reducing the risk of death due to cardiovascular disease in men with hypogonadism. The research suggests that testosterone therapy is an effective approach for secondary prevention in hypogonadal men with a history of cardiovascular events.
A large study of over 9,000 men has established harmonized reference ranges for total testosterone, enabling clinicians to diagnose hypogonadism correctly. The normal range for testosterone in non-obese European and American men between 19-39 years is 264-916 ng/dL.
Researchers developed a method for generating Leydig cells by directly converting adult skin cells into functional testosterone-producing cells. The approach successfully restored normal testosterone levels in male rodents with hypogonadism, offering a promising alternative to existing therapies.
Researchers at the University of Illinois found that mice lacking functional copies of the Bco1 gene had lower blood concentrations of testosterone and smaller prostates. The study suggests that Bco1 may also play a role in regulating prostate growth and androgen synthesis, challenging current understanding of carotenoid metabolism.
Researchers report good results in patients with metastatic prostate cancer using bipolar androgen therapy (BAT), which alternately floods and starves the body of testosterone. The treatment has been safe and effective, with PSA levels falling, tumors shrinking, and some men showing a complete remission.
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Starting testosterone treatment increases risk of serious blood clots, with the risk peaking within six months and declining gradually thereafter. Although the risks are temporary and low in absolute terms, researchers warn that investigating timing and duration of use may have masked conflicting findings.
Researchers from the University of Pennsylvania conducted a study to replicate the original power pose study, finding no support for increases in feelings of power or testosterone. The study also suggested that power poses may decrease testosterone levels in individuals who are already perceived as losers.
A randomized clinical trial found that both treatment arms met the primary safety endpoint, with improvements reported in vaginal atrophy and sexual interest for all patients. The study also revealed that 37% of patients had elevated estradiol levels at baseline, which could be attributed to estrogen-containing supplements.
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A new study suggests that Zika infection can cause testicular damage, leading to reduced fertility and low testosterone levels in male mice. The virus targets Sertoli cells, which are essential for maintaining the barrier between the bloodstream and the testes.
Female meerkats can produce up to twice as much testosterone as males, which may lead to a trade-off in their immune system, making them more prone to infections. Dominant females tend to live longer and give birth to more litters than subordinate females.
A new study found that resveratrol supplements can lower total testosterone levels by 23.1% in women with polycystic ovary syndrome (PCOS), while also improving diabetes risk factors such as fasting insulin levels. The results suggest resveratrol may be a promising treatment for PCOS and related metabolic problems.
Researchers found that male rats with normal testosterone levels had stronger ACLs than those without it. The study suggests a link between testosterone and ACL injuries, which could lead to new techniques for identifying athletes at high risk of injury.
A six-month open-label study found that treatment with a 2% testosterone solution improved low sex drive and low energy symptoms in men with hypogonadism. The safety profile was consistent with previous trials, indicating that long-term treatment is safe and effective.
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Researchers found that a specific gene mutation linked to impulsive behavior also protects carriers from obesity and insulin resistance, which are risk factors for type 2 diabetes. The study suggests that lower testosterone levels in these individuals actually increase insulin sensitivity.
A large placebo-controlled study found that testosterone therapy significantly improved sexual interest and function in older men with low libido and low testosterone levels. The study, the largest of its kind, showed consistent improvement in most types of sexual activity among those who received testosterone therapy.
A consensus conference of international experts found testosterone therapy to be effective in treating low testosterone levels, regardless of underlying origin. The panel rejected concerns about increased cardiovascular risk, stating that the evidence suggests potential cardio-protective effects.
A systematic review of 40 studies found a weak correlation between signs, symptoms, and testosterone levels in ageing men. The authors suggest that it is difficult to extrapolate the diagnosis of pathologic hypogonadism from younger men to older men with age-related testosterone declines.
Researchers found that the testes of larger, more aggressive dark-eyed juncos produced more testosterone, leading to flashier plumage and other traits influenced by testosterone. The study challenges the prevailing theory that hormonally regulated trait differences are controlled largely by the brain.
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A large analysis of medical records in Sweden found that men taking testosterone therapy for over a year had no increased risk of prostate cancer and, in fact, had their risk reduced by 50 percent. The study's findings suggest that balancing testosterone levels within a normal range may be key to protecting against aggressive disease.
A recent study found that testosterone therapy improved erectile function and intercourse satisfaction in men with severe hypogonadism, a condition often associated with type 2 diabetes. The study suggests that trials of testosterone therapy should last at least 6 months for optimal results.
A new study from Wake Forest University found that testosterone influences the evolution of a waving display in male Bornean rock frogs. The research revealed that testosterone increases foot-flagging behavior and changes how hormones act on leg muscles, similar to the change seen in vocal croaks.
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Researchers have identified how low testosterone raises diabetes risk by impairing insulin regulation in the pancreas. Testosterone triggers key signaling mechanisms that produce insulin, and its absence leads to glucose intolerance.
Researchers at Johns Hopkins Bloomberg School of Public Health have discovered a way to encourage adult stem cells to proliferate and differentiate into testosterone-producing cells. The findings could lead to the development of transplantable cells that can produce testosterone, avoiding side effects associated with current treatments.
A large-scale population-based study found that older men using testosterone therapy had lower rates of hospital readmissions compared to non-users. The study, published in Mayo Clinic Proceedings, analyzed data from over 6,000 men and showed a 9.8% rate of 30-day hospital readmissions among testosterone users versus 13% for non-users.
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A new study from Intermountain Medical Center Heart Institute shows that testosterone supplementation reduced major adverse cardiovascular events in elderly men with low testosterone levels and pre-existing coronary artery disease. The study found that patients receiving testosterone therapy had a lower risk of heart attacks, strokes, ...
In a clinical trial of 100 obese men, researchers found that adding testosterone treatment to calorie restriction resulted in increased fat loss and preserved muscle mass. The study suggests that testosterone treatment may be a useful adjunct to weight loss in obese men with low testosterone levels.
Researchers found testosterone treatment improved all aspects of sexual function, including sexual activity and desire, in men with low testosterone levels. However, the study did not confirm earlier concerns about cardiovascular safety.
Researchers found testosterone treatment benefits older men with low testosterone levels, improving sexual function, walking ability, and mood. The treatment also had no significant impact on energy but reduced depressive symptoms.
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