US testosterone prescriptions dropped significantly following reports linking use to cardiovascular events. Between 2013-2016, new users saw a 62% decrease, while established users saw a 48% drop, according to the University of Texas Medical Branch at Galveston study.
SourceUniversity of Texas Medical Branch at Galveston·JournalJAMA·DateJul 10, 2018
A study published in Nature Communications found that testosterone increases men's preference for luxury products associated with high social status, rather than power or quality. The research team tested 243 male participants and found a causal link between testosterone levels and increased liking for status-enhancing goods.
SourceINSEAD·JournalNature Communications·DateJul 3, 2018
A new study led by Gideon Nave found that giving men a single dose of testosterone increased their preference for higher-status goods. The study measured participants' preferences and positive attitudes about products, serving as a foundation for forecasting consumer behavior.
SourceUniversity of Pennsylvania·JournalNature Communications·DateJul 3, 2018
Researchers discovered that men with higher levels of testosterone have a stronger preference for luxury brands, such as Calvin Klein jeans over Levi's. This is because testosterone promotes behaviors associated with status-seeking and status-protecting, similar to animal behaviors like aggression.
SourceCalifornia Institute of Technology·JournalNature Communications·DateJul 3, 2018
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A new study found increased levels of estrogen in men with migraine, as well as symptoms of lower testosterone. Testosterone levels did increase before a migraine in some participants, and symptoms of relative testosterone deficiency were more frequent and severe in men with migraine.
SourceAmerican Academy of Neurology·JournalNeurology·DateJun 27, 2018
A new study from Durham University found that men's testosterone levels are largely determined by their environment during childhood. The research suggests that men who grew up in challenging conditions may have lower testosterone levels in later life.
SourceDurham University·JournalNature Ecology & Evolution·DateJun 25, 2018
Research suggests that children's tendency to share is linked to their social status in the classroom, with those having few interaction partners tending to be more generous. Higher levels of prenatal testosterone are associated with a 'masculinisation effect' leading to less sharing.
SourceUniversity of Vienna·JournalScientific Reports·DateJun 15, 2018
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A new study reveals that testosterone regulates the levels of protein BAFF, which affects B cell production in the spleen. This link has significant implications for understanding and treating autoimmune diseases like lupus.
SourceUniversity of Gothenburg·JournalNature Communications·DateJun 5, 2018
A study of over 2,800 postmenopausal women found that a higher proportion of male to female sex hormones was associated with a significant increase in cardiovascular disease risk. The researchers suggest that having a more male-like hormone profile may affect heart disease risk independent of other risk factors.
SourceJohns Hopkins Medicine·JournalJournal of the American College of Cardiology·DateMay 29, 2018
A higher testosterone to estradiol ratio is associated with an elevated risk of cardiovascular disease, coronary heart disease, and heart failure. Higher total testosterone levels are linked to an increased risk of coronary heart disease and total cardiovascular disease.
SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateMay 28, 2018
A recent study found that rapid weight loss following sleeve gastrectomy can rapidly reverse obesity-related hypogonadism in morbidly obese men, restoring normal levels of testosterone and sex drive. The study showed a significant increase in testosterone levels after one month, while estradiol levels fell.
SourceEuropean Association for the Study of Obesity·DateMay 25, 2018
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A new study found that low total testosterone levels are associated with chronic disease in men of all ages, including those under 40. The research team studied the relationship between testosterone, age, and chronic disease prevalence, using a population sample from the National Health and Nutrition Examination Survey.
SourceMichigan Medicine - University of Michigan·JournalScientific Reports·DateApr 19, 2018
A new male birth control pill called dimethandrolone undecanoate (DMAU) appears to be safe and effective when used daily for a month. The study found that DMAU suppresses levels of testosterone and two hormones required for sperm production, providing consistent contraception.
A study found that sleep restriction leads to insulin resistance in men, which can be mitigated by controlling testosterone and cortisol hormones. This imbalance may explain the increased risk of type 2 diabetes in sleep-deprived men.
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The Endocrine Society has released updated guidelines for testosterone prescribing practices, recommending reserving therapy for men with well-documented hypogonadism. The guidelines also suggest individualizing treatment decisions for older men and avoiding routine testing for healthy men.
SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology & Metabolism·DateMar 17, 2018
A recent study published in Endocrine Practice found that only a quarter of transgender women could lower their testosterone levels within the female range using spironolactone and estrogen therapy. The researchers identified four groups with varying degrees of testosterone suppression, highlighting the need for further studies to unde...
SourceBoston University School of Medicine·JournalEndocrine Practice·DateFeb 20, 2018
A study published in Computers in Human Behavior found no significant changes in testosterone levels among UNLV's esports players during gameplay. The research suggests that familiar environments and competition may not elicit the same hormonal responses as unfamiliar situations and large audiences.
SourceUniversity of Nevada, Las Vegas·JournalComputers in Human Behavior·DateFeb 16, 2018
Researchers identified a guardian molecule triggered by testosterone that protects males from disease. Treatment with the molecule eliminated symptoms in female mice, offering hope for new MS therapies.
SourceNorthwestern University·JournalProceedings of the National Academy of Sciences·DateJan 29, 2018
Researchers found that women with PCOS have less diverse gut bacteria compared to those without the condition. Elevated testosterone levels in PCOS may contribute to these changes, suggesting a potential link between the microbiome and the development of PCOS.
SourceUniversity of California - San Diego·JournalThe Journal of Clinical Endocrinology & Metabolism·DateJan 23, 2018
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A new study found that increasing testosterone levels in young male traders causes them to bid up prices, leading to price bubbles and crashes. The researchers suggest limiting the risk taken by these traders to prevent biased decision-making.
SourceInstitute for Operations Research and the Management Sciences·JournalMarketing Science·DateOct 10, 2017
Researchers found that winning a competition makes people more willing to pay for luxury items and assign greater value to them. Contrary to expectations, testosterone levels were unaffected by winning or losing.
SourceUniversity of Cambridge·JournalScientific Reports·DateSep 19, 2017
A new study found that fathers' testosterone levels after childbirth are linked to their own and partners' depressive symptoms. Low testosterone levels were associated with fewer symptoms of depression in women, while high levels led to more stress and relationship aggression.
SourceUniversity of Southern California·JournalHormones and Behavior·DateSep 5, 2017
Golden-collared manakin males use cleanliness to attract mates and exhibit complex courtship displays. In contrast, females show no motivation to clean their male counterparts' displays, suggesting hormonal influence is specific to males.
SourceSmithsonian Tropical Research Institute·JournalAnimal Behaviour·DateSep 1, 2017
A new study by researchers at the Ivey Business School found that elevated testosterone levels in male traders increased bid prices and asset price bubbles, leading to market instability. The experiment showed that testosterone drove changes in market dynamics by increasing bidding, selling prices, and volume.
SourceUniversity of Western Ontario, Ivey Business School·JournalManagement Science·DateAug 16, 2017
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A new study shows significant improvement in sexual and urinary function as well as quality of life for hypogonadal men undergoing long-term testosterone replacement therapy. Testosterone therapy is found to increase bladder emptying, improve erectile/sexual health and overall quality of life.
SourceBoston University School of Medicine·JournalThe Journal of Urology·DateAug 15, 2017
Research reveals that testosterone plays a crucial role in regulating canary birdsong by targeting specific brain regions involved in singing. The nucleus of the arcopallium (RA) regulates song unit production, while HVC influences syntactical features such as syllable repetition and trill duration.
Researchers found that testosterone reduces the effectiveness of anti-inflammatory drugs in men, increasing prostaglandins and promoting inflammatory reactions. This discovery supports the need for gender-specific medicine, suggesting that treatment may require separate 'his' and 'hers' medicine cabinets.
SourceFriedrich-Schiller-Universitaet Jena·JournalScientific Reports·DateJul 26, 2017
A recent study on California mice found that surges of testosterone before and after aggressive encounters lead to future wins. Winning experiences change the brain's response to testosterone, fueling competitiveness and confidence.
SourceWake Forest University·JournalHormones and Behavior·DateJul 20, 2017
Researchers at Cold Spring Harbor Laboratory have identified the specific hormone receptors and brain regions responsible for masculinization in mice. The study found that estrogen receptor alpha is essential in inhibitory neurons for male sexual and aggressive behaviors to emerge, while deleting it had no impact on excitatory neurons.
SourceCold Spring Harbor Laboratory·JournalHormones and Behavior·DateJul 19, 2017
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A new study highlights the need to improve testosterone prescribing practices in the VA, with variations found in age, experience, specialty, and region. Providers under 40 were more likely to prescribe testosterone, while those over 60 were less likely.
SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology & Metabolism·DateJul 18, 2017
Research reveals that naturally produced testosterone in some elite female athletes gives them a competitive advantage in athletics events that depend on stamina and visuospatial abilities. Women with high levels of free testosterone performed significantly better in certain events, such as the 400m sprint and hammer throw.
SourceBMJ Group·JournalBritish Journal of Sports Medicine·DateJul 3, 2017
A new study from the University of Copenhagen found that paracetamol can reduce sex drive and aggressive behavior in mice by inhibiting testosterone development. The research suggests that pregnant women should exercise caution when taking paracetamol, as it may have unintended effects on their children's masculinity.
SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalReproduction·DateJun 22, 2017
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A study by Australian researchers has found that testosterone suppresses the production of immune cells that trigger allergic asthma. The finding may lead to new, targeted treatments for the disease. Women are two times more likely to develop asthma than men after puberty due to testosterone's protective effects.
SourceWalter and Eliza Hall Institute·JournalJournal of Experimental Medicine·DateMay 8, 2017
A study found that testosterone administration impairs cognitive reflection in men, making them more likely to rely on their gut instincts. The researchers tested the hypothesis that higher levels of testosterone increase the tendency to make intuitive judgments and reduce self-reflection.
SourceCalifornia Institute of Technology·JournalPsychological Science·DateApr 28, 2017
High testosterone levels are associated with competitive, status-seeking social behaviors, while low testosterone is linked to cooperative behaviors. Researchers found that mixed populations with a balance of high and low-testosterone individuals are more likely to form effective social hierarchies.
SourceUniversity of Texas at Austin·JournalHormones and Behavior·DateApr 24, 2017
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The study found that E4 lowered testosterone levels in healthy male volunteers, with decreasing total and free testosterone, FSH, and estradiol levels. The hormone was well-tolerated, with only libido decrease and nipple tenderness reported.
A study found a strong association between TV advertising for testosterone therapies and increased testing, new prescriptions, and treatment initiation. The increase in testosterone use was particularly notable among men without clear indications for treatment.
Direct-to-consumer ads for low-testosterone treatments increase prescriptions but may not improve men's health, according to UC Davis physician Richard Kravitz. The rise in hormone-replacement therapies has led to unnecessary treatments and potential cardiovascular risks.
SourceUniversity of California - Davis Health·JournalJAMA·DateMar 21, 2017
Researchers found that soldiers who exhibited less change in both testosterone and cortisol levels in response to stress were more likely to later show PTSD symptoms. The study suggests future research could investigate preventative interventions targeting those with at-risk hormone profiles.
SourceUniversity of Texas at Austin·JournalPsychoneuroendocrinology·DateMar 7, 2017
Research by Ben-Gurion University finds that men's psychological momentum, driven by testosterone increases after success, leads to exaggerated risk-taking in financial markets. This can create price bubbles. The study suggests that increasing women in financial markets may help stabilize these markets.
SourceAmerican Associates, Ben-Gurion University of the Negev·JournalJournal of Economic Behavior & Organization·DateMar 1, 2017
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A new study published in JAMA and J AMA Internal Medicine found that testosterone therapy improved bone density and strength, as well as reduced anemia in older men with low testosterone levels. However, the therapy had no impact on cognitive function and may worsen plaque in coronary arteries.
Studies published in JAMA and JAMA Internal Medicine found that testosterone treatment was associated with improved bone density and anemia in men with low testosterone. However, the studies also found no significant association between testosterone treatment and improved cognitive function or reduced risk of cardiovascular problems.
Men treated with testosterone replacement therapy had a 33% lower risk of heart attacks and strokes compared to those who didn't receive hormone therapy. Androgen deficiency is characterized by low testosterone levels, which can cause symptoms like erectile dysfunction and hot flashes.
SourceKaiser Permanente·JournalJAMA Internal Medicine·DateFeb 21, 2017
Research found testosterone treatment improved bone density and anemia for men over 65 with low testosterone, while also increasing plaque buildup in coronary arteries. However, cognitive function remained unchanged.
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A new study published in JAMA suggests that testosterone treatments may increase the risk of heart disease in older men. The study found a significant increase in arterial plaque among men aged 65 and older who received testosterone replacement therapy for a year, with a 20% rise in total coronary and noncalcified plaque volumes.
A study published in JAMA and JAMA Internal Medicine found that testosterone treatment improved bone density and anemia, but not cognitive function, in older men with low testosterone. However, it also increased plaque buildup in coronary arteries, raising concerns about cardiac risk.
SourceUniversity of Pennsylvania School of Medicine·JournalJAMA·DateFeb 21, 2017
A new study found that long-term testosterone therapy improves vigor and vitality, while reducing the risk of death due to cardiovascular disease in men with hypogonadism. The research suggests that testosterone therapy is an effective approach for secondary prevention in hypogonadal men with a history of cardiovascular events.
SourceBoston University School of Medicine·JournalJournal of Cardiovascular Pharmacology and Therapeutics·DateFeb 13, 2017
A large study of over 9,000 men has established harmonized reference ranges for total testosterone, enabling clinicians to diagnose hypogonadism correctly. The normal range for testosterone in non-obese European and American men between 19-39 years is 264-916 ng/dL.
SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology & Metabolism·DateJan 10, 2017
Researchers developed a method for generating Leydig cells by directly converting adult skin cells into functional testosterone-producing cells. The approach successfully restored normal testosterone levels in male rodents with hypogonadism, offering a promising alternative to existing therapies.
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Researchers at the University of Illinois found that mice lacking functional copies of the Bco1 gene had lower blood concentrations of testosterone and smaller prostates. The study suggests that Bco1 may also play a role in regulating prostate growth and androgen synthesis, challenging current understanding of carotenoid metabolism.
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·DateDec 7, 2016
Researchers report good results in patients with metastatic prostate cancer using bipolar androgen therapy (BAT), which alternately floods and starves the body of testosterone. The treatment has been safe and effective, with PSA levels falling, tumors shrinking, and some men showing a complete remission.
SourceECCO-the European CanCer Organisation·DateNov 30, 2016
Starting testosterone treatment increases risk of serious blood clots, with the risk peaking within six months and declining gradually thereafter. Although the risks are temporary and low in absolute terms, researchers warn that investigating timing and duration of use may have masked conflicting findings.
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Researchers from the University of Pennsylvania conducted a study to replicate the original power pose study, finding no support for increases in feelings of power or testosterone. The study also suggested that power poses may decrease testosterone levels in individuals who are already perceived as losers.
SourceUniversity of Pennsylvania·JournalHormones and Behavior·DateNov 28, 2016
A randomized clinical trial found that both treatment arms met the primary safety endpoint, with improvements reported in vaginal atrophy and sexual interest for all patients. The study also revealed that 37% of patients had elevated estradiol levels at baseline, which could be attributed to estrogen-containing supplements.
A new study suggests that Zika infection can cause testicular damage, leading to reduced fertility and low testosterone levels in male mice. The virus targets Sertoli cells, which are essential for maintaining the barrier between the bloodstream and the testes.
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Female meerkats can produce up to twice as much testosterone as males, which may lead to a trade-off in their immune system, making them more prone to infections. Dominant females tend to live longer and give birth to more litters than subordinate females.
SourceDuke University·JournalScientific Reports·DateOct 20, 2016
A new study found that resveratrol supplements can lower total testosterone levels by 23.1% in women with polycystic ovary syndrome (PCOS), while also improving diabetes risk factors such as fasting insulin levels. The results suggest resveratrol may be a promising treatment for PCOS and related metabolic problems.
SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology & Metabolism·DateOct 18, 2016
Researchers found that male rats with normal testosterone levels had stronger ACLs than those without it. The study suggests a link between testosterone and ACL injuries, which could lead to new techniques for identifying athletes at high risk of injury.
SourceJohns Hopkins Medicine·JournalThe Knee·DateOct 11, 2016
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A six-month open-label study found that treatment with a 2% testosterone solution improved low sex drive and low energy symptoms in men with hypogonadism. The safety profile was consistent with previous trials, indicating that long-term treatment is safe and effective.
SourceElsevier Health Sciences·JournalThe Journal of Urology·DateAug 17, 2016
Researchers found that a specific gene mutation linked to impulsive behavior also protects carriers from obesity and insulin resistance, which are risk factors for type 2 diabetes. The study suggests that lower testosterone levels in these individuals actually increase insulin sensitivity.
SourceUniversity of Helsinki·JournalJournal of Psychiatric Research·DateAug 10, 2016