Mount Sinai researchers have found that testosterone treatment is safer than previously reported, with a smaller degree of change in hematocrit levels. The study, involving over 6,670 transmasculine patients, suggests that providers can feel more comfortable prescribing testosterone as part of gender-affirming hormone therapy.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalThe Journal of Clinical Endocrinology and Metabolism·DateNov 27, 2023
Researchers identified a correlation between the HSD3B1 biomarker and resistance to combined hormone therapy and radiotherapy in men with prostate cancer. The study found that high levels of the enzyme led to increased testosterone production, promoting resistance to treatment.
SourceCleveland Clinic·JournalJournal of Clinical Investigation·DateNov 20, 2023
Jenny Wilkerson receives $1.94 million grant to develop novel models and investigate antinociceptive profiles of basal sex hormone alterations in patients with chronic post-op pain. The study aims to answer questions about the impact of altered sex hormone levels on recovery times, drug effectiveness, and long-term health.
SourceTexas Tech University Health Sciences Center·DateNov 13, 2023
Researchers investigated the role of estrogen receptor beta-positive neurons in the medial amygdala, a region involved in social information processing. They found that MeA-ERβ+ neurons exhibit different roles for receptivity-based and sex-based preferences.
SourceUniversity of Tsukuba·JournalProceedings of the National Academy of Sciences·DateOct 15, 2023
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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A worldwide audit of testosterone deficiency in men with type 2 diabetes found that testosterone replacement therapy improves glycaemic control for up to 2 years. The study suggests that the ongoing effect of testosterone on insulin resistance and fat reduction contributes to the improvement in blood sugar levels.
A study found that severe erythrocytosis, where hematocrit is over 54%, is a rare outcome of testosterone therapy in adults. Researchers recommend reevaluating the need for frequent lab screenings to minimize unnecessary draws among patients who prefer not to undergo regular checks.
SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateSep 25, 2023
UTHSC researchers are studying the role of balanced sex hormones in DNA repair in human melanocytes to determine if hormonal imbalances contribute to melanoma risk. The study aims to find novel prevention methods to decrease melanoma cases and potentially save lives.
SourceUniversity of Tennessee Health Science Center·DateSep 20, 2023
A randomized clinical trial found immediate testosterone therapy significantly reduced gender dysphoria, depression, and suicidality in transgender and gender-diverse individuals. The study included 64 participants and compared immediate testosterone therapy to no treatment.
SourceJAMA Network·JournalJAMA Network Open·DateSep 7, 2023
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Women with polycystic ovary syndrome (PCOS) who follow a keto diet for at least 45 days may experience significant weight loss and improvements in reproductive hormone levels. Lower testosterone levels can also help reduce excess hair growth and other symptoms associated with PCOS.
SourceThe Endocrine Society·JournalJournal of the Endocrine Society·DateSep 7, 2023
A USC Stem Cell-led mouse study reveals that lowering testosterone can improve the resilience of male kidneys by reducing their vulnerability to disease. The researchers also found that three months of calorie restriction has a similar effect, suggesting new potential treatments for kidney diseases.
SourceKeck School of Medicine of USC·JournalDevelopmental Cell·TypeExperimental study·DateSep 5, 2023
The study found that rising testosterone levels trigger full song development and territorial behavior in thrush nightingales. Full songsters were never found to settle close to each other, while plastic songsters settled close to both full and plastic songsters, indicating a connection between song and territoriality.
SourceMax-Planck-Gesellschaft·JournalProceedings of the Royal Society B Biological Sciences·TypeObservational study·DateAug 30, 2023
Two studies demonstrate that artificial intelligence in colonoscopy can increase adenoma detection rates and reduce miss rates, but also lead to increased removal of non-neoplastic polyps. The findings suggest the need for additional research on more defined detection parameters before AI can be integrated into routine clinical care.
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeNews article·DateAug 28, 2023
New study finds that men who suffered from mild COVID-19 have lower sperm concentrations and motility even three months after recovery. The researchers believe that the virus may cause permanent damage to male fertility, leading to long-term decline in semen quality.
SourceEuropean Society of Human Reproduction and Embryology·TypeObservational study·DateJun 26, 2023
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AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Higher testosterone levels during adolescence enhance emotion control, but decrease in young adulthood; the study suggests a shift in testosterone's role across developmental periods. The findings may be related to mood disorders that arise during adolescence.
A randomized clinical trial found that rapid access to testosterone therapy significantly reduced feelings of gender dysphoria and depression among transgender adults. The study also showed a 50% reduction in suicidal ideation compared to those on a standard waiting list.
Research in mice suggests that prostate cancer cells adapt to testosterone-deprivation therapy by producing cholesterol and generating their own testosterone. Treating aggressive tumors with inhibitors slows tumor growth. The study also points to a possible drug combination and sheds light on racial disparities in prostate cancer.
SourceWashU Medicine·JournalNature Communications·DateJun 9, 2023
Sons of women with PCOS are two times more likely to develop obesity and have high levels of male hormones, leading to insulin resistance and type 2 diabetes. A mouse study confirms these findings, showing fat tissue and metabolism problems in the offspring despite a healthy diet.
SourceKarolinska Institutet·JournalCell Reports Medicine·DateMay 5, 2023
ENZAMET, a new drug combination, has shown significant improvement in survival rates for men with advanced prostate cancer. After five years, the treatment led to a 67% survival rate, compared to 57% for standard therapy.
SourceUniversity of Adelaide·JournalThe Lancet Oncology·TypeRandomized controlled/clinical trial·DateMar 27, 2023
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Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
A new study published in Evolutionary Psychology examines the relationship between parental income and the sexual behavior of their adult children. The research found that children from low-income families had higher frequencies of same-sex attraction, while those from high-income families had lower frequencies.
SourceSwansea University·JournalEvolutionary Psychology·TypeObservational study·DateDec 16, 2022
A Northwestern Medicine study found that online platforms are offering therapies to men who don't meet guidelines for testosterone deficiency, while failing to convey the risks and benefits of therapy. The study recommends seeing a provider with expertise in hypogonadism for accurate care.
SourceNorthwestern Memorial HealthCare·JournalJAMA Internal Medicine·DateDec 5, 2022
A recent meta-analysis published in Human Reproduction Update reveals a significant worldwide decline in sperm counts of over 50% in the past 46 years. The study also shows an accelerated post-2000 decline in sperm counts globally.
SourceThe Hebrew University of Jerusalem·JournalHuman Reproduction Update·TypeMeta-analysis·DateNov 15, 2022
Experts found that large differences in finger length between left and right hands are associated with COVID-19 severity. The study may help identify those at greatest risk of hospitalization across age groups.
SourceSwansea University·JournalFrontiers in Public Health·TypeRandomized controlled/clinical trial·DateNov 2, 2022
A study analyzing nearly 1,500 young men found that standard cutoff points for low testosterone levels may not be accurate. Age-specific thresholds ranged from 409 ng/dL at 20-24 years to 350 ng/dL at 40-44 years, indicating the need for a more personalized approach to diagnosing testosterone deficiency in younger men.
SourceWolters Kluwer Health·JournalThe Journal of Urology·DateOct 28, 2022
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GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Recruitment of tumor-fighting macrophages depends on testosterone. Administering testosterone to females increases macrophage ability to eradicate tumor cells.
A study of 15 transgender women found they exceeded the cardiopulmonary capacity and muscle strength of their cisgender peers even after years of hormone therapy. However, their performance was lower than that of cisgender men. The findings could inform policy on transgender women's sports participation.
SourceBMJ Group·JournalBritish Journal of Sports Medicine·TypeObservational study·DateOct 4, 2022
A randomized phase III trial found that combination hormonal therapy, delivered for a finite treatment interval of 12 months, more durably suppresses PSA levels compared to hormone injections alone. The treatment approach improved disease progression in patients with high-risk biochemically relapsed prostate cancer.
SourceAlliance for Clinical Trials in Oncology·DateSep 9, 2022
Research by Saint Louis University School of Medicine and Washington University School of Medicine found that low testosterone levels are associated with an increased risk of hospitalization from COVID-19. Men with low testosterone were twice more likely to require hospitalization than those with normal levels.
SourceSaint Louis University·JournalJAMA Network Open·DateSep 2, 2022
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
A study by researchers at Washington University School of Medicine found that low testosterone levels are an independent risk factor for COVID-19 hospitalization in men. Men with chronically low testosterone who developed COVID-19 were 2.4 times more likely to require hospitalization than those with normal testosterone levels.
SourceWashU Medicine·JournalJAMA Network Open·TypeObservational study·DateSep 2, 2022
A new animal study finds that testosterone can foster friendly, prosocial behavior in males, in addition to aggression. The hormone appears to help animals rapidly pivot between prosocial and antisocial responses as the social world changes.
SourceEmory University·JournalProceedings of the Royal Society B Biological Sciences·TypeExperimental study·DateAug 11, 2022
A new study explores relationships between domestic cats' hormone levels, gut microbiomes, and social behaviors in cohabitating groups. The research found that low testosterone and cortisol concentrations enabled cats to share space, while high oxytocin levels were associated with less affiliative behavior.
SourcePLOS·JournalPLOS ONE·TypeObservational study·DateJul 27, 2022
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers found higher AR signaling and better response rates for female patients treated with BRAF/MEK inhibitors. Blocking the AR improved response to BRAF/MEK targeted therapy in both males and females.
SourceUniversity of Texas M. D. Anderson Cancer Center·JournalNature·DateJun 15, 2022
A mouse study suggests that active testosterone therapy can lead to fewer and less developed eggs retrieved during IVF. Discontinuing testosterone therapy appears to have no significant impact on reproductive capacity, however.
SourceThe Endocrine Society·JournalJournal of the Endocrine Society·DateJun 13, 2022
A randomized controlled trial shows significant improvements in testosterone replacement therapy for men with poorly-controlled type 2 diabetes and hypogonadism. The treatment improved symptoms, libido, and quality of life, as well as delayed verbal recall, a potential early sign of dementia.
SourceThe Endocrine Society·JournalJournal of the Endocrine Society·DateJun 11, 2022
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Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Two experimental male contraceptive pills, DMAU and 11β-MNTDC, have shown promising results in lowering testosterone levels without unacceptable side effects. The study found that 75% of men who took the active drug were willing to use it in the future, compared to 46.4% of those taking a placebo.
SourceThe Endocrine Society·JournalJournal of the Endocrine Society·DateJun 11, 2022
A comprehensive analysis of testosterone replacement therapy found no increased risk of heart attack, stroke, and other cardiovascular events in the short-to-medium term. Testosterone treatment was also found to reduce serum cholesterol levels, but no significant differences were observed in blood pressure or glycaemic parameters.
SourceThe Lancet·JournalThe Lancet Healthy Longevity·TypeSystematic review·DateJun 8, 2022
Research finds no significant increase in cardiovascular events among men with low testosterone undergoing testosterone treatment. Testosterone was found to reduce serum total cholesterol and triglycerides, but no significant differences were seen in other parameters.
SourceThe Endocrine Society·JournalThe Lancet Healthy Longevity·TypeMeta-analysis·DateJun 8, 2022
Patients with lower levels of sex hormones are more likely to undergo surgery for rotator cuff tears, according to a study published in The Journal of Bone & Joint Surgery. Estrogen deficiency was associated with a 48% higher incidence of rotator cuff repair in women, while testosterone deficiency was linked to an 89% higher rate in men.
SourceWolters Kluwer Health·JournalJournal of Bone and Joint Surgery·DateApr 13, 2022
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
A study found that strength training activates androgen receptors to protect against muscle pain in mice. Resistance training also alleviated pain only in male mice, while females did not show similar benefits. The findings suggest exercise may be a useful treatment for chronic musculoskeletal pain.
A study published in Scientific Reports found that patients with 'feminized' short fingers tend to experience severe Covid-19 symptoms, while those with large right-hand-left hand differences have elevated probabilities of hospitalization. The research suggests a link between low testosterone and high oestrogen levels and Covid severity.
SourceSwansea University·JournalScientific Reports·TypeRandomized controlled/clinical trial·DateMar 25, 2022
In meerkat societies, testosterone-driven aggression enables cooperative breeding by creating a hierarchy where subordinates help raise the matriarch's pups. Researchers found that matriarchs' high testosterone levels drive their aggressive behavior, which maintains group structure.
SourceDuke University·JournalNature Communications·TypeObservational study·DateDec 17, 2021
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Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
Scientists at Kobe University have successfully generated testosterone-producing Leydig cells from human iPS cells, a significant step towards developing a regenerative medicine treatment for late-onset hypogonadism. The induced cells expressed genes specific to Leydig cells and produced functional testosterone.
SourceKobe University·JournalJournal of Endocrinology·TypeExperimental study·DateNov 28, 2021
A study published in The Journal of Sex Research found that higher testosterone levels are associated with having multiple partners in men and solitary sexual activity in women. The research, which analyzed data from nearly 4,000 adults, highlights the complex relationship between hormones and human sexuality.
SourceTaylor & Francis Group·JournalThe Journal of Sex Research·DateOct 11, 2021
A study found that early weight loss in obese boys can improve reproductive function and reverse alterations in Leydig cell function, which could help prevent future fertility problems. The research suggests that managing childhood obesity may be necessary to prevent reproductive issues and lower the risk of other diseases.
SourceEuropean Society for Paediatric Endocrinology·JournalHormone Research in Paediatrics·TypeObservational study·DateSep 23, 2021
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Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Researchers found that UVB phototherapy increases levels of romantic passion and aggression in both men and women. Exposure to sunlight affects the endocrine system's regulation of sexual hormones.
SourceTel-Aviv University·JournalCell Reports·DateAug 25, 2021
A case study reports success in restoring hormone balance to a castrated dog, improving mobility, reducing anxiety, and alleviating various health issues. The treatment involved testosterone and GnRH agonist therapy, resulting in significant health improvements.
SourceParsemus Foundation·JournalTopics in Companion Animal Medicine·TypeCase study·DateAug 20, 2021
A University of Houston researcher is using cutting-edge techniques to study how testosterone affects the brain and social behavior. Using genetically modified African cichlid fish, Beau Alward aims to identify the specific genes and neurons involved in these processes.
A new study found that higher testosterone levels are linked to socioeconomic position in men but not women. In contrast, lower testosterone was associated with poorer health and risk-taking behavior in women. The research suggests that testosterone may be less important than previously thought in determining success.
SourceUniversity of Bristol·JournalScience Advances·DateJul 28, 2021
A new study found that supplementing testosterone significantly reduces heart attacks and strokes in men with unnaturally low hormone levels. The 10-year study involved over 800 men from Germany and Qatar, showing a 25% reduction in risk for those under 55 and a 15% reduction for those over 60.
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CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Research shows that men with symptomatic Covid-19 and low testosterone are more likely to become severely ill and die. The lower the testosterone levels, the higher the likelihood of severe illness and death, according to a study presented at the European Association of Urology congress.
A study found that wildfires alter male red-backed fairywrens' plumage, making them less attractive to females, while also lowering circulating testosterone. This suggests an evolved response to minimize breeding during unfavorable environmental conditions.
SourceWashington State University·JournalJournal of Avian Biology·DateJun 30, 2021
A two-year study found that testosterone therapy normalised testosterone levels, reduced NAFLD, and suppressed symptoms of hypogonadism in obese men. Testosterone therapy may help obese men with functional hypogonadism and type-2 diabetes reduce the prevalence of non-alcoholic fatty liver disease.
A new study from Washington University School of Medicine found that low testosterone levels in men are linked to more severe disease. Men with low testosterone had a higher risk of requiring intensive care or dying from COVID-19, while those with higher testosterone levels were less likely to experience severe symptoms.
SourceWashU Medicine·JournalJAMA Network Open·DateMay 25, 2021
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Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
A low-calorie ketogenic diet has been found to increase total testosterone and sex hormone (SHBG) levels in overweight men. After four weeks on the diet, body weight, fat mass, and BMI decreased significantly, while testosterone and SHBG levels substantially increased.
A diet high in pro-inflammatory foods may be associated with increased odds of developing testosterone deficiency among men. Men who consume refined carbohydrates and sugar, as well as polyunsaturated fats, are more likely to experience low libido, decreased energy, and depression.
SourceWolters Kluwer Health·JournalThe Journal of Urology·DateApr 21, 2021
A study by The Endocrine Society finds oral testosterone therapy undecanoate (TU) is an effective treatment for men with low testosterone levels, with a safety profile consistent with non-oral products. TU has minimal effects on cholesterol levels and no liver toxicity was reported.
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Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
A new marker of testicular cell capacity identified as a promising biological marker, INSL3, shows suppressed levels in former steroid users compared to never-users. Long-lasting impaired gonadal capacity found in previous anabolic steroid users, increasing risk of hypogonadism later in life.
SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology & Metabolism·DateMar 9, 2021
A new study published in Hypertension Journal Report found that a structured exercise program improved artery health and function in middle-aged and older men with low-to-normal testosterone levels. The study showed no benefits from testosterone therapy on artery health.
A study published by The Endocrine Society found that testosterone therapy increases the risk of blood clots, heart attack, and stroke in transgender men. Over 11% of participants developed erythrocytosis, a condition characterized by excessive red blood cells.
SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology & Metabolism·DateFeb 18, 2021
Research suggests that lower testosterone during puberty increases the brain's sensitivity to it in adulthood. Men with lower testosterone levels throughout puberty showed greater brain activity in areas sensitive to faces when exposed to high levels of testosterone.
Research suggests that high-income mothers tend to produce higher levels of testosterone, leading to a more masculinized fetus, while low-income mothers produce lower levels of testosterone, resulting in a more feminized fetus. This phenomenon has been linked to increased disease risk, including cardiovascular disease and mortality.
SourceSwansea University·JournalJournal of Biosocial Science·DateFeb 9, 2021
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