Testosterone
Articles tagged with Testosterone
The 28th European Congress of Endocrinology (ECE) starts tomorrow
AI-driven wearable patches help identify undetected hormone disruption in unexplained infertility
Study finds cancer location determines how testosterone regulates tumor growth
NIH-funded study suggests that testosterone suppresses brain tumor growth in males
A NIH-funded study discovered that testosterone may play a key role in limiting brain tumor growth in men by suppressing inflammation and stress hormone production. Analysis of over 1,300 men with glioblastoma found that supplemental testosterone was significantly associated with improved survival rates.
World Hormone Day 2026
The European Society of Endocrinology organizes World Hormone Day to educate the public about hormone-related health issues. Global endocrine disorders affect millions worldwide, emphasizing the need for proper hormone balance.
Testosterone level not a given sign of well-being
A higher testosterone level does not always indicate well-being in men, according to a study at the University of Gothenburg. Muscle health and inflammation are linked to testosterone levels, but symptoms like fatigue and depression have weaker connections.
Treating disease at birth: How a brief spike in testosterone sets the trajectory for a disease that appears decades later
Researchers at Nagoya University found that a brief spike in testosterone after birth causes muscle-wasting disease to develop decades later. Treating the disease at birth significantly reduced nerve cell breakdown in adult mice.
CNIO research links fertility with immune cells in the brain
A study published in Science reveals that microglia and the protein RANK are involved in regulating the hypothalamic-pituitary-gonadal axis, which controls fertility. The research found that suppressing RANK expression led to distorted reproductive function, including reduced sex hormones and hypogonadism.
Low testosterone, high fructose: A recipe for liver disaster
A study published in American Journal of Physiology-Endocrinology and Metabolism found that low testosterone and high fructose intake synergistically contribute to liver damage in mice. The researchers discovered that changes in gut microbiota led to increased levels of pyruvate, which promotes fat accumulation in the liver.
Could finger length provide vital clue to understanding human brain evolution?
A study of 225 newborns found that high prenatal oestrogen levels, indicated by long index fingers, are associated with large head circumference and increased brain size in boys. This could provide evidence for the positive influence of prenatal oestrogen on human brain evolution
‘Masculinity crisis’: Influencers on social media promote low testosterone to young men, study finds
A new study found that social media influencers are promoting unproven claims about low testosterone in young men, framing common experiences as hormonal deficiencies. The content is linked to the manosphere, encouraging hyper-masculine ideals and positioning testosterone as a way for men to reclaim power and status.
Teeth of babies of stressed mothers come out earlier, suggests study
Research shows that infants of stressed mothers have an earlier and faster tooth eruption, with more teeth by six months of age. Cortisol levels during late pregnancy are associated with this accelerated process.
Message from the oldest-living dogs to dogs and men: Gonad function fights frailty
A study by the Gerald P. Murphy Cancer Foundation's Center for Exceptional Longevity Studies found that retaining gonad function can significantly impact frailty mortality risk. Male dogs with shortest testis exposure had high mortality risks, while those with longest gonad exposure showed no consequence of increasing frailty.
New EndoCompass Research Roadmap calls for coordinated investment to tackle Europe’s hormone health challenge
The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.
Testosterone doesn’t affect men’s economic decisions, large study shows
A large-scale study examining the impact of testosterone on economic decision-making has found no significant effects. The study, which involved 1,000 men, used a double-blind trial to test the influence of testosterone on risk-taking, generosity, and competitiveness.
A chemical conversation: NSF CAREER award to examine how mothers prime offspring for environmental challenges
Bentz will investigate how maternal hormones shape behavior across generations in House sparrows, with implications for understanding animal adaptation. The research aims to identify gene networks that respond to early testosterone exposure and track changes from development through adulthood.
Mount Sinai-Duke University study identifies DNA variants that increase testosterone production in PCOS patients
A study by Mount Sinai-Duke University identifies specific DNA variants in the DENND1A gene that increase testosterone production in PCOS patients. This finding could lead to new therapies targeting the genetic source of elevated testosterone levels in PCOS, which is a common condition affecting reproductive-age women.
Anti-obesity medications can normalize testosterone levels in men
A new study found that anti-obesity medications can normalize testosterone levels in men with obesity or type 2 diabetes. This positive effect on reproductive health was observed after a 10% weight loss, with total and free testosterone levels increasing by 24%.
High blood sugar may have a negative impact on men’s sexual health
A long-term study of healthy men found that minimally elevated blood sugar levels can lead to declines in sperm movement and erectile function. The study suggests that lifestyle choices and medical interventions can help preserve or revive reproductive health in aging men.
Clues in the claws: finger length may reveal sexual preferences in rats
Researchers found that rats with shorter second digits exhibit stronger sexual behavior, including a preference for female scent and frequent ejaculations. This study reveals the impact of fetal hormone exposure on brain development and highlights the link between body and mind.
Placenta and hormone levels in the womb may have been key driver in human evolution, say researchers
A new hypothesis suggests that prenatal sex steroid hormones and placental function played a crucial role in shaping the human brain and its cognitive traits. This may have led to increased brain size and reduced competition among males, allowing for the emergence of large social groups.
No increased risk of gynecological cancer with testosterone use after five years
A large-scale study published in eClinicalMedicine found that transmasculine and gender-diverse individuals who use testosterone for an average of five years do not have an increased risk of gynecological cancer. The research, which followed 1955 participants, suggests that hormone therapy may be safe for this group.
Manuel Heitor to share perspectives on the future of research in Europe at launch of EndoCompass
The EndoCompass project aims to guide future studies and funding programs with a research roadmap for better hormone health in Europe. Manuel Heitor will share his perspective on the future of research in Europe, emphasizing the need for greater investment and coordination.
Testosterone during pregnancy linked to physical activity and muscle strength in children
Research found that boys born to mothers with polycystic ovary syndrome (PCOS) or higher testosterone levels during pregnancy are less physically active at age 7. Girls exposed to similar levels of testosterone had lower muscle strength, highlighting the role of maternal testosterone and PCOS in future development.
Interview opportunity: Women are overtaking men in the most extreme sports events
A recent study found that women are more metabolically efficient under extreme conditions, closing the performance gap with men. Women's greater fat mass may contribute to this advantage, enabling them to complete longer distances without burning out.
Rice statistician earns $1 million CPRIT award to advance AI-powered precision medicine for prostate cancer
A Rice University statistician has received a $1 million CPRIT award to advance AI-powered precision medicine for prostate cancer. The project aims to identify lethal forms of prostate cancer earlier and improve treatment selection using AI tools and advanced imaging techniques.
How footballers’ fingers and height can predict their exercise performance
A new study found that female professional footballers' lactate levels can be predicted by their finger length and height. Research showed that tall women and those with a long ring finger relative to their index finger produced low levels of lactate during exercise.
Simple treatment can save lives for men with a common chromosomal disorder
A Danish study reveals that testosterone treatment can nearly halve the mortality rate among men with Klinefelter syndrome, reducing cardiovascular disease risk and increasing life expectancy. The treatment also improves quality of life and may have positive effects on metabolism, muscle mass, and bone health.
Testosterone increases damage following a heart attack
A study from the University of Gothenburg found that testosterone increases damage following a heart attack by increasing white blood cell release from bone marrow. This affects both men and women, but has a greater impact on male hearts.
Super enzyme breaks down testosterone
Research revealed a single gene drives the production of a super enzyme in male ruff's blood, which rapidly breaks down testosterone. This process regulates sex hormones and influences mating behaviors in non-aggressive males.
Super enzyme that regulates testosterone levels in males discovered in ‘crazy’ bird species
Researchers at Simon Fraser University and the Max Planck Institute have identified a single gene controlling testosterone levels in three male morphs of shore birds, also applicable to vertebrates including humans. This super enzyme (HSD17B2) rapidly breaks down testosterone, producing diverse mating behaviors.
Save the date: European Society of Endocrinology (ESE) and ESE Foundation announce inaugural World Hormone Day
The European Society of Endocrinology (ESE) and ESE Foundation will host the first-ever World Hormone Day on April 24, 2025. The campaign aims to raise public awareness of good hormone health and improve national political engagement for better prevention, diagnosis, and treatment of endocrine disease.
Pups of powerful meerkat matriarchs pay a price for their mom’s status
A new study by Duke University researchers reveals that pups of dominant female meerkats, exposed to higher levels of testosterone in the womb, tend to carry more gut parasites and have weaker immune systems. Blocking a matriarch's testosterone improved the health of her pups, leading to stronger natural defenses against infection.
Hormone therapy affects the metabolic health of transgender individuals
Long-term hormone therapy in transgender individuals leads to significant changes in body composition and risk factors for cardiovascular disease. Transgender men experience increased muscle volume and abdominal fat, while women's muscle mass decreases, according to a new study published in the Journal of Internal Medicine.
How long ring fingers can point to a love of alcohol
A new study by Swansea University researchers found a relationship between high alcohol consumption and long ring fingers compared to index fingers. The study used a sample of 258 university students and revealed that high prenatal testosterone relative to oestrogen is linked to high alcohol consumption in men, but not women.
State policies regulating law enforcement access to prescription drug monitoring program testosterone prescription data
State policies allow law enforcement unfettered access to sensitive medical information without warrants or subpoenas in over half the country, sparking concerns about patient privacy and civil liberties. The lack of regulation puts gender-affirming care patients at risk, amid growing bans on such treatments.
Study helps predict how long it will take for testosterone to return to normal after prostate cancer treatment
A new study has found that baseline testosterone, age, and duration of ADT are key predictors of testosterone recovery. The researchers developed a nomogram to estimate recovery times based on patient-specific characteristics, providing valuable insights for improving patient outcomes.
How stressed are you? Nanoparticles pave the way for home stress testing
Researchers have developed a cost-effective and easily reproducible point-of-care testing device that can accurately measure cortisol levels in the blood. The device uses iridium oxide nanoparticles to improve stability, sensitivity, and selectivity, allowing for commercial use.
Risks faced by women using anabolic steroids in Australia
A new study reveals critical insights into the challenges faced by women who use anabolic-androgenic steroids (AAS) in Australia, highlighting a significant knowledge gap in sports medicine. The research emphasizes the need for tailored harm-reduction interventions and education on AAS use to mitigate risks associated with counterfeit ...
Experts provide further proof of role testosterone plays in preventing severe Covid
A new study published in Andrology has found that patients with lower testosterone levels tend to have short little fingers, which is associated with an increased risk of severe Covid-19. The research suggests that testosterone may reduce inflammation in the lungs and other organs, providing a protective effect against severe illness.
Removal of ovaries before menopause associated with reduced white matter integrity in brain
Researchers found that women who had their ovaries removed before menopause experience reduced white matter integrity in multiple brain regions. This reduction may contribute to an increased risk of cognitive decline and dementia later in life.
OU one of four funded by NCCN for innovative prostate cancer research
The University of Oklahoma has been awarded a $1.2 million grant to lead a Phase 1B clinical trial for the treatment of prostate cancer when it begins to spread beyond the prostate. The trial combines two existing drugs, relugolix and enzalutamide, which may provide more effective treatments for aggressive prostate cancer patients.
Study finds potentially treatable factors to improve symptoms in men stopping illicit steroids
A study found that men who stopped using illicit steroids within the past year experienced lower sexual function scores, depression, and anxiety compared to those currently using steroids. Having a psychiatric diagnosis and lower testosterone levels were associated with greater impairment in these areas.
Testosterone therapy: A safe and effective gender-affirming hormone therapy for trans men
A study published in Andrology found that testosterone therapy significantly improves body composition in transgender men, with no long-term side effects. Researchers also discovered that higher doses of testosterone may lead to faster results.
Low testosterone in men associated with higher risk for death
A systematic review and meta-analysis found that low testosterone levels are associated with increased risk of all-cause mortality and cardiovascular death. Men with very low testosterone concentrations had a significantly higher risk of cardiovascular death, regardless of other hormone levels.
Zebra finch chicks don't babble for no reason
Research at the Max Planck Institute for Biological Intelligence reveals that zebra finch chicks' first vocalizations play a key role in memorizing adult songs. The chicks' babbling is necessary to initiate the sensory phase of song learning, enabling them to store and recall the learned song.
A third of trans masculine individuals on testosterone ovulate
A third of trans masculine individuals taking testosterone are found to ovulate, according to a study from Amsterdam UMC's Center of Expertise on Gender Dysphoria. This discovery emphasizes the importance of birth control measures and comprehensive care for trans men who may experience unplanned pregnancy.
Common hair loss and prostate drug may also cut heart disease risk in men and mice
A new study suggests that finasteride, a common hair loss and prostate drug, may also lower cholesterol levels and reduce cardiovascular disease risk in men. In mice, the researchers found significant correlations between finasteride use and lower cholesterol levels, as well as reduced inflammation and atherosclerosis progression.
New study analyzes link between digit ratio and oxygen consumption in footballers
A recent study by Swansea University analyzed the link between digit ratio and oxygen consumption in professional football players. The research found that athletes with longer ring digits relative to their index fingers had more efficient oxygen metabolism, reaching high maximal oxygen consumption during a cardiopulmonary test.
Anabolic steroid use can increase heart disease risk
A new study has found that anabolic steroid use can increase the risk of atrial fibrillation in individuals with existing genetic predisposition to heart diseases. Researchers discovered that testosterone and other male sex hormones used for muscle building can lead to electrical problems in the heart, particularly in young men.
Mechanism linking anxiety to testosterone discovered by Ben-Gurion University scientists
Researchers found a significant connection between anxiety disorders and the brain receptor TACR3, as well as low testosterone levels. Testing showed that inhibiting TACR3 resulted in increased receptors on the cell surface, blocking long-term synaptic strengthening.
Mini marsupial goes from sex fests to cannibal feasts
Researchers have documented cannibalism in the mainland dusky antechinus during its breeding period. The behavior is linked to stress-induced death and provides an opportunity for energy gain via eating dead males or females of other species.
Understanding the neuroendocrine basis for social anxiety-like behavior in male mice
Researchers investigated role of estrogen receptors in lateral septum regulating social anxiety in male mice, finding that ERβ plays a crucial role in neural circuitry. Knockdown effects on ERβ gene expression showed increased social anxiety, highlighting its importance in social situations.
Mount Sinai researchers find testosterone hormone therapy for transmasculine individuals is safer than previously thought
Mount Sinai researchers have found that testosterone treatment is safer than previously reported, with a smaller degree of change in hematocrit levels. The study, involving over 6,670 transmasculine patients, suggests that providers can feel more comfortable prescribing testosterone as part of gender-affirming hormone therapy.
Cleveland Clinic research finds correlation between biomarker HSD3B1 and resistance to combined hormone therapy and radiotherapy
Researchers identified a correlation between the HSD3B1 biomarker and resistance to combined hormone therapy and radiotherapy in men with prostate cancer. The study found that high levels of the enzyme led to increased testosterone production, promoting resistance to treatment.
TTUHSC’s Wilkerson to investigate links between pain and basal sex hormone levels
Jenny Wilkerson receives $1.94 million grant to develop novel models and investigate antinociceptive profiles of basal sex hormone alterations in patients with chronic post-op pain. The study aims to answer questions about the impact of altered sex hormone levels on recovery times, drug effectiveness, and long-term health.
Elucidating the neural basis for expression of estrous female odor preference in male mice
Researchers investigated the role of estrogen receptor beta-positive neurons in the medial amygdala, a region involved in social information processing. They found that MeA-ERβ+ neurons exhibit different roles for receptivity-based and sex-based preferences.
Worldwide audit finds testosterone replacement improves blood sugar control in men with type 2 diabetes
A worldwide audit of testosterone deficiency in men with type 2 diabetes found that testosterone replacement therapy improves glycaemic control for up to 2 years. The study suggests that the ongoing effect of testosterone on insulin resistance and fat reduction contributes to the improvement in blood sugar levels.
Research that severe erythrocytosis is rare among people using testosterone for gender-affirming care
A study found that severe erythrocytosis, where hematocrit is over 54%, is a rare outcome of testosterone therapy in adults. Researchers recommend reevaluating the need for frequent lab screenings to minimize unnecessary draws among patients who prefer not to undergo regular checks.