Articles tagged with Testosterone
The Endocrine Society recommends a diagnosis of hypogonadism based on low testosterone levels and symptoms. Testosterone replacement therapy (TRT) can improve quality of life for men with appropriately diagnosed hypogonadism, but its long-term safety is uncertain. Standardized testing and monitoring are crucial to minimize risks.
A new study from the University of Georgia suggests that higher levels of change in testosterone during early puberty are linked to increased emotional difficulties in girls between ages 10 and 12. The study found that physical development alone is not enough to predict depression and anxiety symptoms in adolescent girls.
A new study found that prenatal oestrogen levels in mothers are positively related to their newborn's head circumference. The researchers also discovered that this influence is stronger for boys than girls, shedding light on the evolutionary drive for larger brains in humans.
A study published by the Endocrine Society found that testosterone therapy was often prescribed without adequate diagnostic testing, highlighting opportunities for quality-improvement efforts. The research suggests that targeted interventions may be needed to improve guideline-concordant prescribing practices and prevent avoidable risks.
A study found that testosterone alone is not enough to prevent type 2 diabetes in older men; lifestyle interventions are crucial for improving blood sugar control and reducing obesity. Testosterone treatment can improve body composition and sexual desire, but its benefits diminish over time.
A new study by UNIGE and SCAHT reveals that cannabis use is associated with an increase in testosterone levels, particularly in the testes. However, this increase does not appear to have a direct link to fertility, and further research is needed to determine potential long-term effects.
A large-scale Nordic study found a link between PCOS and heart disease, with women at increased risk even in normal weight. The study also highlighted the importance of regular medical screenings for women with PCOS.
The ECE 2026 brings together researchers and clinicians to share the latest endocrine research and developments. Key sessions include Plenaries, Symposia, Awards, Meet the Experts, Debates, and Oral Communications.
Researchers developed an AI-driven wearable skin sensor patch to track reproductive hormones and detect hidden endocrine dysfunction, which can improve conception. The study found that men with normal testosterone levels may still have disrupted hormone rhythms associated with reproductive dysfunction.
A new study finds that testosterone slows the growth of glioblastoma in men, contrary to its usual effect on tumors. Blocking testosterone makes tumors grow faster in both male and female patients.
A NIH-funded study discovered that testosterone may play a key role in limiting brain tumor growth in men by suppressing inflammation and stress hormone production. Analysis of over 1,300 men with glioblastoma found that supplemental testosterone was significantly associated with improved survival rates.
The European Society of Endocrinology organizes World Hormone Day to educate the public about hormone-related health issues. Global endocrine disorders affect millions worldwide, emphasizing the need for proper hormone balance.
A higher testosterone level does not always indicate well-being in men, according to a study at the University of Gothenburg. Muscle health and inflammation are linked to testosterone levels, but symptoms like fatigue and depression have weaker connections.
Researchers at Nagoya University found that a brief spike in testosterone after birth causes muscle-wasting disease to develop decades later. Treating the disease at birth significantly reduced nerve cell breakdown in adult mice.
A study published in Science reveals that microglia and the protein RANK are involved in regulating the hypothalamic-pituitary-gonadal axis, which controls fertility. The research found that suppressing RANK expression led to distorted reproductive function, including reduced sex hormones and hypogonadism.
A study published in American Journal of Physiology-Endocrinology and Metabolism found that low testosterone and high fructose intake synergistically contribute to liver damage in mice. The researchers discovered that changes in gut microbiota led to increased levels of pyruvate, which promotes fat accumulation in the liver.
A study of 225 newborns found that high prenatal oestrogen levels, indicated by long index fingers, are associated with large head circumference and increased brain size in boys. This could provide evidence for the positive influence of prenatal oestrogen on human brain evolution
A new study found that social media influencers are promoting unproven claims about low testosterone in young men, framing common experiences as hormonal deficiencies. The content is linked to the manosphere, encouraging hyper-masculine ideals and positioning testosterone as a way for men to reclaim power and status.
Research shows that infants of stressed mothers have an earlier and faster tooth eruption, with more teeth by six months of age. Cortisol levels during late pregnancy are associated with this accelerated process.
A study by the Gerald P. Murphy Cancer Foundation's Center for Exceptional Longevity Studies found that retaining gonad function can significantly impact frailty mortality risk. Male dogs with shortest testis exposure had high mortality risks, while those with longest gonad exposure showed no consequence of increasing frailty.
The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.
A large-scale study examining the impact of testosterone on economic decision-making has found no significant effects. The study, which involved 1,000 men, used a double-blind trial to test the influence of testosterone on risk-taking, generosity, and competitiveness.
Bentz will investigate how maternal hormones shape behavior across generations in House sparrows, with implications for understanding animal adaptation. The research aims to identify gene networks that respond to early testosterone exposure and track changes from development through adulthood.
A study by Mount Sinai-Duke University identifies specific DNA variants in the DENND1A gene that increase testosterone production in PCOS patients. This finding could lead to new therapies targeting the genetic source of elevated testosterone levels in PCOS, which is a common condition affecting reproductive-age women.
A new study found that anti-obesity medications can normalize testosterone levels in men with obesity or type 2 diabetes. This positive effect on reproductive health was observed after a 10% weight loss, with total and free testosterone levels increasing by 24%.
A long-term study of healthy men found that minimally elevated blood sugar levels can lead to declines in sperm movement and erectile function. The study suggests that lifestyle choices and medical interventions can help preserve or revive reproductive health in aging men.
Researchers found that rats with shorter second digits exhibit stronger sexual behavior, including a preference for female scent and frequent ejaculations. This study reveals the impact of fetal hormone exposure on brain development and highlights the link between body and mind.
A new hypothesis suggests that prenatal sex steroid hormones and placental function played a crucial role in shaping the human brain and its cognitive traits. This may have led to increased brain size and reduced competition among males, allowing for the emergence of large social groups.
A large-scale study published in eClinicalMedicine found that transmasculine and gender-diverse individuals who use testosterone for an average of five years do not have an increased risk of gynecological cancer. The research, which followed 1955 participants, suggests that hormone therapy may be safe for this group.
The EndoCompass project aims to guide future studies and funding programs with a research roadmap for better hormone health in Europe. Manuel Heitor will share his perspective on the future of research in Europe, emphasizing the need for greater investment and coordination.
Research found that boys born to mothers with polycystic ovary syndrome (PCOS) or higher testosterone levels during pregnancy are less physically active at age 7. Girls exposed to similar levels of testosterone had lower muscle strength, highlighting the role of maternal testosterone and PCOS in future development.
A recent study found that women are more metabolically efficient under extreme conditions, closing the performance gap with men. Women's greater fat mass may contribute to this advantage, enabling them to complete longer distances without burning out.
A Rice University statistician has received a $1 million CPRIT award to advance AI-powered precision medicine for prostate cancer. The project aims to identify lethal forms of prostate cancer earlier and improve treatment selection using AI tools and advanced imaging techniques.
A new study found that female professional footballers' lactate levels can be predicted by their finger length and height. Research showed that tall women and those with a long ring finger relative to their index finger produced low levels of lactate during exercise.
A Danish study reveals that testosterone treatment can nearly halve the mortality rate among men with Klinefelter syndrome, reducing cardiovascular disease risk and increasing life expectancy. The treatment also improves quality of life and may have positive effects on metabolism, muscle mass, and bone health.
A study from the University of Gothenburg found that testosterone increases damage following a heart attack by increasing white blood cell release from bone marrow. This affects both men and women, but has a greater impact on male hearts.
Research revealed a single gene drives the production of a super enzyme in male ruff's blood, which rapidly breaks down testosterone. This process regulates sex hormones and influences mating behaviors in non-aggressive males.
Researchers at Simon Fraser University and the Max Planck Institute have identified a single gene controlling testosterone levels in three male morphs of shore birds, also applicable to vertebrates including humans. This super enzyme (HSD17B2) rapidly breaks down testosterone, producing diverse mating behaviors.
The European Society of Endocrinology (ESE) and ESE Foundation will host the first-ever World Hormone Day on April 24, 2025. The campaign aims to raise public awareness of good hormone health and improve national political engagement for better prevention, diagnosis, and treatment of endocrine disease.
A new study by Duke University researchers reveals that pups of dominant female meerkats, exposed to higher levels of testosterone in the womb, tend to carry more gut parasites and have weaker immune systems. Blocking a matriarch's testosterone improved the health of her pups, leading to stronger natural defenses against infection.
Long-term hormone therapy in transgender individuals leads to significant changes in body composition and risk factors for cardiovascular disease. Transgender men experience increased muscle volume and abdominal fat, while women's muscle mass decreases, according to a new study published in the Journal of Internal Medicine.
A new study by Swansea University researchers found a relationship between high alcohol consumption and long ring fingers compared to index fingers. The study used a sample of 258 university students and revealed that high prenatal testosterone relative to oestrogen is linked to high alcohol consumption in men, but not women.
State policies allow law enforcement unfettered access to sensitive medical information without warrants or subpoenas in over half the country, sparking concerns about patient privacy and civil liberties. The lack of regulation puts gender-affirming care patients at risk, amid growing bans on such treatments.
A new study has found that baseline testosterone, age, and duration of ADT are key predictors of testosterone recovery. The researchers developed a nomogram to estimate recovery times based on patient-specific characteristics, providing valuable insights for improving patient outcomes.
Researchers have developed a cost-effective and easily reproducible point-of-care testing device that can accurately measure cortisol levels in the blood. The device uses iridium oxide nanoparticles to improve stability, sensitivity, and selectivity, allowing for commercial use.
A new study reveals critical insights into the challenges faced by women who use anabolic-androgenic steroids (AAS) in Australia, highlighting a significant knowledge gap in sports medicine. The research emphasizes the need for tailored harm-reduction interventions and education on AAS use to mitigate risks associated with counterfeit ...
A new study published in Andrology has found that patients with lower testosterone levels tend to have short little fingers, which is associated with an increased risk of severe Covid-19. The research suggests that testosterone may reduce inflammation in the lungs and other organs, providing a protective effect against severe illness.
Researchers found that women who had their ovaries removed before menopause experience reduced white matter integrity in multiple brain regions. This reduction may contribute to an increased risk of cognitive decline and dementia later in life.
The University of Oklahoma has been awarded a $1.2 million grant to lead a Phase 1B clinical trial for the treatment of prostate cancer when it begins to spread beyond the prostate. The trial combines two existing drugs, relugolix and enzalutamide, which may provide more effective treatments for aggressive prostate cancer patients.
A study found that men who stopped using illicit steroids within the past year experienced lower sexual function scores, depression, and anxiety compared to those currently using steroids. Having a psychiatric diagnosis and lower testosterone levels were associated with greater impairment in these areas.
A study published in Andrology found that testosterone therapy significantly improves body composition in transgender men, with no long-term side effects. Researchers also discovered that higher doses of testosterone may lead to faster results.
A systematic review and meta-analysis found that low testosterone levels are associated with increased risk of all-cause mortality and cardiovascular death. Men with very low testosterone concentrations had a significantly higher risk of cardiovascular death, regardless of other hormone levels.
Research at the Max Planck Institute for Biological Intelligence reveals that zebra finch chicks' first vocalizations play a key role in memorizing adult songs. The chicks' babbling is necessary to initiate the sensory phase of song learning, enabling them to store and recall the learned song.
A third of trans masculine individuals taking testosterone are found to ovulate, according to a study from Amsterdam UMC's Center of Expertise on Gender Dysphoria. This discovery emphasizes the importance of birth control measures and comprehensive care for trans men who may experience unplanned pregnancy.
A new study suggests that finasteride, a common hair loss and prostate drug, may also lower cholesterol levels and reduce cardiovascular disease risk in men. In mice, the researchers found significant correlations between finasteride use and lower cholesterol levels, as well as reduced inflammation and atherosclerosis progression.
A recent study by Swansea University analyzed the link between digit ratio and oxygen consumption in professional football players. The research found that athletes with longer ring digits relative to their index fingers had more efficient oxygen metabolism, reaching high maximal oxygen consumption during a cardiopulmonary test.
A new study has found that anabolic steroid use can increase the risk of atrial fibrillation in individuals with existing genetic predisposition to heart diseases. Researchers discovered that testosterone and other male sex hormones used for muscle building can lead to electrical problems in the heart, particularly in young men.
Researchers found a significant connection between anxiety disorders and the brain receptor TACR3, as well as low testosterone levels. Testing showed that inhibiting TACR3 resulted in increased receptors on the cell surface, blocking long-term synaptic strengthening.
Researchers have documented cannibalism in the mainland dusky antechinus during its breeding period. The behavior is linked to stress-induced death and provides an opportunity for energy gain via eating dead males or females of other species.
Researchers investigated role of estrogen receptors in lateral septum regulating social anxiety in male mice, finding that ERβ plays a crucial role in neural circuitry. Knockdown effects on ERβ gene expression showed increased social anxiety, highlighting its importance in social situations.