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SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Protein Sirtuin 7 suppresses heat production in brown adipose tissue

Researchers found that Sirtuin 7 regulates brown adipose tissue functions, leading to suppressed energy expenditure and thermogenesis. The study reveals a molecular pathway involving protein deacylation and mRNA binding, which will have implications for treating hypermetabolic conditions like cancer and obesity.

AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Discovering sirtuin longevity proteins in early branches of animal life

A study from University of California, Davis, and Harvard Medical School reveals multiple new sirtuins in early branching animals like jellyfish, sea sponges, and sea anemones. These proteins are involved in metabolism and DNA repair, playing a crucial role in the unique longevity strategies of these animals.

Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Biologists find a way to boost intestinal stem cell populations

Researchers found that aging contributes to a decline in intestinal stem cells, which can lead to disorders of the gastrointestinal tract. Boosting these cells with a compound called nicotinamide riboside (NR) reverses this effect and provides protection against age-related damage.

New health benefits discovered in berry pigment

A study from the University of Eastern Finland has found that anthocyanins in berries increase SIRT6 enzyme levels and decrease cancer genes in human cells. The findings suggest a potential role for anthocyanins in preventing cancer growth, paving the way for new drug development.

Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

Feast-and-famine diet could extend life, study shows

Researchers found that an intermittent feast-and-famine diet increased sirtuin proteins, which promote longevity and protect against age-related diseases. The diet also decreased insulin levels, potentially having an anti-diabetic effect.

A fattening gene

Researchers have identified a key gene in energy metabolism, revealing its crucial role in regulating fat storage. The Sirt7 gene plays a central role in the process, enabling mice to maintain normal weight despite high-fat diets, suggesting new therapeutic approaches for obesity and metabolic disorders.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

SIRT5 regulation has dramatic effect on mitochondrial metabolism

Researchers have identified widespread regulation of proteins involved in metabolism by the mitochondrial sirtuin, SIRT5. This study found that SIRT5 selectively removes specific sites of succinyl modifications in over 140 different proteins, leading to disruptions in metabolic pathways.

Study finds mechanism that turns white fat into energy-burning brown fat

Researchers at Columbia University Medical Center have identified a mechanism that can give energy-storing white fat some of the beneficial characteristics of energy-burning brown fat. By activating a cell receptor called ppar-gamma, scientists found that sirtuins boost metabolism by promoting the browning of white fat.

More evidence for longevity pathway

New research confirms resveratrol's role in prolonging lifespan and health through SIRT1-activated mitochondrial function. Studies using mouse models show that without SIRT1, resveratrol has no beneficial effect on energy production.

NIH study uncovers probable mechanism underlying resveratrol activity

A new NIH study reveals that resveratrol's health benefits come from inhibiting phosphodiesterases (PDEs), not directly activating sirtuin 1. This finding may pave the way for resveratrol-based medicines and offer alternative treatments for diseases like type 2 diabetes, Alzheimer's disease, and heart disease.

Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

Scientists ferret out a key pathway for aging

A study by University of Wisconsin-Madison scientists identifies Sirt3 as a crucial enzyme in the aging process, which helps to slow down aging by reducing free radicals produced by mitochondria. The findings provide a rational basis for devising interventions to retard aging and improve health in old age.

SIRT1 gene important for memory

A study led by the University of Southern California found that SIRT1 protein is essential for recall in mice, but over-expression did not improve performance; instead, it raised questions about supplementing with sirtuin activators.

Study strengthens link between sirtuins and life extension

Researchers strengthen the connection between sirtuins and calorie restriction's life-extending effects by targeting a brain system controlling growth and lifespan length. The findings suggest that drugs boosting sirtuin production could help fight diseases of aging, improving health in later life.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Future diabetes treatment may use resveratrol to target the brain

A new study found that resveratrol improves diabetes by targeting the brain, potentially leading to orally-delivered medications. Activating sirtuins in the brain mediates resveratrol's beneficial effects, which could lead to more effective targeted diabetes treatments.

'SIRT'ain security: the protein SIRT3 protects the heart

A new study reveals that Sirt3 helps protect the mouse heart by blocking cardiac hypertrophic response through Foxo3a-dependent antioxidant defense mechanisms. Mice lacking Sirt3 developed enlarged hearts, while those overexpressing Sirt3 were protected from cardiac hypertrophy under similar conditions.

Researchers identify a potentially universal mechanism of aging

Scientists have discovered that DNA damage can lead to a decrease in gene regulation, contributing to aging. A specific sirtuin protein helps regulate gene expression and maintain DNA repair, but its dysfunction can result in chronic gene activation and aging phenotypes.

GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Does a component of niacin point the way to anti-aging drugs?

A new study from The Wistar Institute suggests that a component of the common vitamin B3, nicotinamide, binds to sirtuin molecules and inhibits their activity. Activating these enzymes could have anti-aging effects and help counteract age-related health problems like obesity and type II diabetes.

Researchers find new clues to biochemistry of 'anti-aging'

Sirtuins have been implicated in the health benefits of calorie restriction, which is known to lengthen life span. The discovery reveals that sirtuins directly control specific metabolic enzymes called AceCSs, transforming them into a form that allows the body to utilize acetate as an energy source.

SIRT7

Researchers at Cold Spring Harbor Laboratory have identified SIRT7 as a key regulator of cellular metabolism and longevity. The study reveals that SIRT7 promotes the activity of key enzymes involved in glucose and lipid metabolism, leading to improved energy balance and lifespan.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

New insights on sirtuins, involved in gene expression and aging

Scientists at The Wistar Institute discovered a binding site that, if blocked, could activate the protein to promote genomic stability and decrease cancer. By analyzing the molecular details of how sirtuins work, researchers identified potential activators using virtual libraries of molecules.

Molecules discovered that extend life in yeast, human cells

A group of polyphenols found in red wine and vegetables have been shown to activate sirtuins, enzymes that help cells survive environmental stresses and may promote longevity. These molecules, called STACs, were found to stimulate human sirtuin SIRT1, increasing cell survival rates.

Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.