A recent study from Baylor College of Medicine describes an elaborate gene network that functions in causing mutations during DNA repair in stressed cells. The network, composed of 93 genes, regulates the production of mutations in response to environmental challenges such as starvation or antibiotics.
A Michigan State University research team discovered that doctors who listen carefully to their patients have happier patients with better health outcomes. The study found that patient-centered relationships reduce brain activity in the anterior insula, a region responsible for pain perception, and lead to lower self-reported pain levels.
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A new study reveals that time-of-day specific treatment with a synthetic glucocorticoid can shift the circadian rhythms of atria samples, but with different effects on the direction of shifts compared to the liver. The study highlights the sensitivity of the heart's circadian clock to glucocorticoid signaling.
Researchers at Kansas State University are using the new mass spectrometer to analyze plant responses to heat, cold, and other stresses. By studying Arabidopsis thaliana, a model plant species, they aim to improve crop plants' ability to withstand environmental stress.
A new study suggests that social contact can lower pain responses and inflammation in mice with nerve damage. The study found that paired mice showed reduced signs of inflammation and allodynia behavior compared to isolated mice.
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Researchers found that women who read negative news had higher cortisol levels after a psychological stress test compared to men. Women also showed stronger emotional responses to the negative news they had viewed previously, suggesting a gender difference in how we react to negative news in the media.
About 30% of blacks retain as much salt as eating fries when stressed, leading to elevated blood pressure and increased cardiovascular disease risk. A low-salt diet may be beneficial for these individuals.
Dr. Margaret A. Goodell is awarded the 2012 William Dameshek Prize for her groundbreaking work on hematopoietic stem cells and their role in regulating the immune response.
In uncertain environments, organisms use molecular processes to make guesses about the future, according to a study. Genetic identical individuals exhibit variation in stress responses due to random decisions, which is beneficial as it reduces metabolic costs without compromising overall benefits.
A study by Penn State researchers has found that exposure to violence among adolescents can have lasting physical stress response effects up to a year after the exposure. Cortisol levels were found to be lower in males with higher exposure to violence, suggesting an evolutionary adaptation to suppress cortisol levels.
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Researchers found that severe sleep loss affects white blood cell counts, particularly granulocytes, which react immediately to physical stress and mirror the body's stress response. The study suggests implications for clinical practice and professions associated with long-term sleep loss.
A Stanford-led study found that short-term stress stimulates immune activity, mobilizing key cells to fight infections and wounds. The research offers hope for developing new treatments to improve recovery from surgery or vaccines.
Researchers found that rats exposed to vinclozolin as fetuses showed increased anxiety, sensitivity to stress, and altered brain activity in their third-generation offspring. This study suggests epigenetic transgenerational inheritance may play a role in the development of post-traumatic stress syndrome and other mental disorders.
A pioneering study found that increased maternal choline intake during pregnancy can decrease children's chances of developing hypertension and diabetes. The researchers believe choline alters gene expression patterns involved in cortisol production, potentially reducing stress-related diseases.
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A new study offers a fresh perspective on the immune system's acute-phase response, which creates systemic stress that can harm both healthy cells and pathogens. By viewing this response as 'immune brinksmanship,' researchers argue that it may be beneficial for natural selection.
A study using integrative Personal Omics Profiling (iPOP) combines genome sequencing, disease risk analysis, and molecular measures to capture changes in human biology. The researchers observe tens of thousands of components over two years, revealing dynamic molecular-level changes that provide meaningful physiological information.
A study found that referees' stress tolerance is not linked to their physical condition but rather to the state of their nervous system. Researchers observed significant stress levels in referees both before and after matches, including during sleep hours.
A study shows that unemployment stress is more closely tied to local green space than age, income, or deprivation. The presence of parks and woodland in economically deprived areas can help people cope with job losses and reduce cortisol levels.
A new clinical trial combines two medications to address anxiety and physiological stress before, during, and after surgery. This approach aims to increase long-term survival rates by up to 300 percent in cancer patients.
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Researchers found that unhealthy narcissism is more than twice as large a predictor of cortisol in males as in females, indicating chronic HPA axis activation. The study suggests that societal definitions of masculinity may contribute to the physiological effects of narcissism on men.
Researchers develop novel approach to enhance plant stress response, increasing crop yield under drought conditions. By modifying abscisic acid receptors, the team achieves prolonged activation of stress response pathways, paving the way for breeding more resilient crops.
Researchers at Tufts University have discovered a novel mechanism regulating stress response in the brain, involving neurosteroids and specific receptors. Blocking these receptors may lead to new approaches for managing stress-related disorders such as depression, epilepsy, and obesity.
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A study led by Dr. Charles Marmar found that police recruits with higher cortisol awakening responses were more likely to experience acute stress symptoms in response to trauma years later. The study suggests that measuring cortisol levels could be a potential indicator for identifying those at high risk for PTSD.
Researchers at Caltech found that bacterial cells respond to stress by continuously flipping genes on and off, similar to a heater switching on and off. This pulsating mechanism, triggered by molecular fluctuations, could drive other cellular processes and reveal more about how life works.
A study from the University of Rochester found that chronic stress disrupts a mother's natural stress response, leading to problematic parenting behaviors. Mothers with higher depressive symptoms exhibited hyperactive stress responses, resulting in harsh and reactive parenting.
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Researchers discovered that stress induces a re-wiring in the brain, impairing endocannabinoids' ability to regulate food intake and contributing to enhanced food drive. Blocking stress hormones prevented this effect, suggesting a potential therapeutic target for manipulating food intake.
A new study found that acute stress can increase alcohol consumption by altering its effects, while chronic stress may prolong recovery from a stressful event. The study's results suggest that using alcohol to cope with stress may actually make a person's response to stress worse.
Scientists at Buck Institute discover that inhibiting an mRNA translation factor increases stress response genes and extends lifespan in C. elegans. The study highlights the importance of mRNA translation in aging and may lead to the development of therapeutics to slow age-related diseases.
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Researchers are using computational approaches to analyze and unify data on plant responses to environmental stresses, aiming to improve crop stress adaptation abilities. The Beacon database will facilitate the curation and archiving of signaling pathways for abiotic stress responses.
A study published in the Journal of Neuroscience reveals that social stress can increase inflammation among brain cells, leading to anxiety-like behaviors. The researchers found that immune cells migrated to the brain in response to social stress, triggering an inflammatory response and a specific activation pattern of neurons.
Researchers at ISU have discovered a new pathway that allows plants to activate a response to environmental stress, leading to reduced yields. Understanding this pathway could lead to the development of crops that can tolerate stress and maintain high productivity.
A history of childhood abuse increases adolescent depression risk by altering neuroendocrine response to stress. Cortisol levels build up over time, increasing risk for severe endocrine impairment and depression.
New research from the University of Cincinnati shows that elevated levels of sodium can suppress social anxiety by inhibiting stress hormones in the body. The study found that rats exposed to high sodium levels responded less to stress and displayed reduced cardiovascular responses.
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Researchers found cortisol levels increase when behavior problems first appear, then decrease if issues persist. Interventions should start as soon as behavioral problems emerge to address mental and physical health concerns.
The study found that three urocortin proteins play a central role in regulating stress responses and shutting down the stress response. Genetically engineered mice lacking these proteins showed impaired recovery from stress, highlighting their importance in returning to normal behavior.
High-throughput DNA sequencing of gut bacteria confirmed that antibiotic treatment disrupts bacterial patterns, which precedes VRE colonization and bloodstream invasion. Monitoring fecal bacteria content could identify patients at high risk of life-threatening infections.
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University of Cincinnati researchers found that pleasurable activities like tasty foods and sex can reduce stress by weakening anxiety responses in the brain. The findings suggest a long-term benefit and could potentially provide strategies for intervening in metabolic disorders.
Healthy adults who experienced childhood abuse or neglect may have an elevated inflammatory response to stress, increasing their risk of depression and anxiety disorders. A study found that adults with adverse childhood experiences had higher levels of inflammatory markers, such as interleukin-6, in their blood.
A diet rich in walnuts and walnut oil may improve blood pressure responses to stress by lowering resting blood pressure and inflammation. The study found that adding flaxseed oil did not further lower blood pressure.
A new study by USC researchers found that stressed men have diminished brain activity in regions responsible for understanding others' feelings, whereas stressed women show increased coordination. This sex difference is linked to the effects of stress on social behavior and empathy.
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Toxoplasma gondii parasite triggers stress response mechanism to survive outside host cells, enabling it to find new hosts and infect them. Researchers identify critical pathway that helps the parasite overcome environmental stresses, offering potential new treatments for toxoplasmosis infection.
Researchers at the Buck Institute discovered that insulin signaling affects cell survival and metabolism through translation. The study found that lower insulin signaling is associated with increased tolerance to stress, suggesting a new avenue for disease intervention.
A new study published in The Journal of General Physiology reveals that HCN channels play a crucial role in regulating heart rate during stress. The research provides insight into the mechanisms behind the 'flight-or-fight' response, offering new understanding of this complex physiological process.
Research by Tracy Langkilde reveals that stress hormones increase energy mobilization in lizards, enabling them to flee from fire ants. Elevated glucocorticoid levels in affected species facilitate adaptive responses, improving survival rates and reproductive success.
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A Tufts University study sheds light on how marine animals like Galapagos iguanas survive stress, revealing the crucial role of negative feedback in coping with 'fight or flight' responses. The research also has implications for understanding wildlife responses to environmental disasters and oil spills.
Researchers have developed a non-invasive Respiratory Stress Response (RSR) test that can accurately measure the presence of significant coronary artery disease, with a sensitivity and specificity of 83% and 70%, respectively. The test uses a Pulse Oximeter to measure blood flow in response to paced breathing.
Researchers have discovered a link between stress, anxiety, and metabolic changes that can lead to type 2 diabetes. The study found that increasing the activity of a single gene in the brain causes mice to exhibit anxious behavior and develop symptoms associated with type 2 diabetes.
A recent study reveals that women with premenstrual dysphoric disorder (PMDD) have distinct biological responses to stress and pain, differing from those with major depression. The findings suggest that PMDD is a separate entity from depression, warranting more precise treatments.
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A University of Montreal study found that men and women respond differently to stress, with high blood pressure and heart rate in women who are more defensive. Older men with low defensive reactions have higher cardiovascular rates. The study suggests that socialization and maintaining self-esteem contribute to these responses.
Researchers found patients with significant coronary artery disease had a significantly lower cardiac respiratory stress response compared to those without the condition. The test uses a Pulse Oximeter to measure blood flow in response to paced breathing, with high accuracy and sensitivity.
Elena Baena-González will investigate how plants respond to stress and allocate energy stores, aiming to improve crop yields. Her research focuses on the SnRK1 protein, which is conserved across species, including mammals.
Researchers found that patients with high immune response during surgery recovered faster and had better knee function. Men were more likely to mount the beneficial stress response, leading to full recovery. The study suggests simple blood tests could predict patient recovery months after surgery.
A study published in BMC Medicine found a correlation between severe stress and an increased risk of stroke, particularly among patients with cerebral infarction due to atherosclerosis or blood clots. The study suggests that further research is needed to understand the role of stress in developing certain types of strokes.
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Researchers found that short-term stress enhances anti-tumor activity in mice, with fewer developing skin cancer and lower tumor burden. The stressed mice showed increased levels of immune-activating genes, suggesting a longer-term enhancement of immunity.
Researchers have identified genes in yeast that enable it to respond to stress and are investigating ways to improve its performance by modifying its stress response mechanism. By manipulating these genes, they found a family of enzymes called sirtuins plays an important role in controlling wine yeast lifespan.
Researchers at the University of Texas at San Antonio have published an 11-minute video in JoVE to demonstrate their novel hormone extraction technique. The video provides a clear format for communicating complex scientific experiments and has received nearly 3,000 views since its publication.
A study found that even low levels of lead in children's blood can increase vascular resistance and decrease aldosterone levels, which may predispose them to hypertension. The researchers also discovered increased sympathetic nervous system activity during rest and a paradoxical depression of this response during stressful tasks.
Researchers found that genetic variants impact stress response differently in men and women. Women carrying the BDNF Val/Met genotype were shown to have a lower cortisol response than men with the same genotype, while men with the Val/Val variant exhibited higher cortisol levels.
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Researchers at University of Iowa discovered that calcium/calmodulin-dependent protein kinase II (CaM kinase II) activation can increase heart rates, contrary to traditional beta-adrenergic receptor stimulation understanding. This finding suggests inhibiting CaM kinase II function could help control heart rate problems in people with a...
Arizona State University researchers investigated strategies for resolving stressful interactions, finding that a more limited approach may be healthier. The study involved role-playing a stressful task with an uncooperative 'neighbor' and found that individuals who used fewer negotiation strategies had lower cortisol levels and less i...