Articles tagged with Eukaryotic Genomes
A new study reveals that linker histone H1 initially flits around inside a cell without a clear aim, until a chaperone protein escorts it to its target, the nucleosome. This finding sheds light on how H1 regulates gene expression and compacts DNA, and could lead to new therapies for diseases.
A study led by Dr. Toni Gabaldón rewrites the origin of the first eukaryotes, suggesting a gradual and collaborative process involving multiple bacterial groups and giant viruses. The research provides new insights into the emergence of complex cells in animals, plants, fungi, and protists.
Researchers used long-read sequencing to analyze the nuclear genome of Amorphochlora amoebiformis, revealing an extremely high proportion of introns (74%) compared to other eukaryotic genomes. The study provides important insights into the evolutionary dynamics and potential functional roles of introns in eukaryotic genomes.
The Earth BioGenome Project aims to create a digital library of DNA sequences to preserve and protect life on Earth. The project has revealed a refined strategy to scale up the sequencing of 150,000 species, accelerating biodiversity research and global conservation.
The Universitat Autònoma de Barcelona is part of the international Tree of Sex project, aiming to create a comprehensive database on reproduction in eukaryotes. The UAB will contribute genomic, transcriptomic, and ecological data to expand upon the original initiative.
A team of researchers has comprehensively predicted the location of non-B DNA structures in great apes using newly available telomere-to-telomere genomes. The study suggests that non-B DNA is enriched in these segments and may play a role in genetic diseases and cancer, with potential new functions discovered.
The study reveals that eukaryogenesis occurred abruptly at a critical gene length of 1,500 nucleotides, marking the emergence of the eukaryotic cell. This phase transition was algorithmic, driven by the tension between increasing gene length and protein complexity.
A joint research group clarifies a key mechanism of how retrotransposons preferentially insert in the centromere. The findings reveal strong integration biases for certain genetic elements, shedding light on rapid genome evolution.
Researchers analyzed genome of Oikopleura dioica, finding it has wildly different languages despite identical physical characteristics. The 'scrambling' phenomenon suggests genes are regulated differently, challenging assumptions about species identity.
Researchers, led by Elizabeth King, aim to develop a knowledge base on complex genetic traits using fruit fly models. The project seeks to address the scientific knowledge gap in this field by focusing on interconnectedness among multiple factors.
A new study challenges a popular scenario explaining the origin of eukaryotes, suggesting that cells can grow to considerable volume without acquiring mitochondria. Researchers explore energy requirements and genome arrangement in prokaryotes and eukaryotes, revealing overlap between cell types rather than a hard boundary line.
Researchers have discovered an alternative way of organizing genes in coral symbiont dinoflagellates, with alternating unidirectional blocks and a 3D chromosome structure dependent on transcriptional activity. This unique genome organization challenges traditional understanding of eukaryotic genetics.
The Earth BioGenome Project is a 10-year scientific grand challenge to document life on Earth. The project's challenges include international coordination and governance, economic benefits, and biodiversity conservation.
The American Society for Cell Biology announced the winners of the 2015 Kaluza Prizes, recognizing outstanding graduate student bioscience research. Ten young scientists received cash and travel awards for their contributions to cell biology.
LitInspector is a powerful literature and pathway mining system that offers quick and easy retrieval of pathways, genes, gene functions, and gene-gene interactions. The system utilizes cutting-edge text mining technology and leverages the largest gene synonym table available to provide comprehensive results.
Researchers used Genomatix tools to identify novel cancer-associated genes in a colon cancer model. The study validated the findings using siRNA knock-down and RT-PCR, confirming the importance of these genes in cell proliferation.
Genomatix Software GmbH has won a $1.6 million BioChance grant to research RNAi mediated regulatory networks. The two-year project will expand its competence in this field, complemented by academic partners from LMU Munich and DKFZ Heidelberg.
Genomatix Software GmbH has appointed a distributor in China, Beijing ZGZ Science and Technology Development Co., Ltd., to expand its market presence. This partnership is significant for Genomatix, with over 1,800 researchers in China subscribed to its free services.