Articles tagged with Type 2 Diabetes
Scientists have discovered a potential new treatment approach for non-alcoholic fatty liver disease by targeting a receptor called Adgrf1. Overexpressing Adgrf1 improved insulin sensitivity and reduced lipid accumulation in liver cells, suggesting its role in fat metabolism.
Researchers have identified four metabolism-related biomarkers linked to an increased risk of metastatic prostate cancer in Black men. These biomarkers could lead to improved testing and treatments for this high-risk population, who are more than twice as likely to die from the disease.
A new study found that intensive lifestyle intervention, including weekly counseling on diet and exercise, is associated with increased employment among people with type 2 diabetes. Study participants without a college degree had even larger employment gains from lifestyle changes recommended by specialists.
An intensive lifestyle intervention was associated with increased employment rates and improved labor market outcomes. The study suggests that such interventions can positively impact individuals with type 2 diabetes, highlighting the importance of considering labor market productivity in disease management.
Researchers at West Virginia University are tracing the cause of diabetic heart disease using diabetic animal models to examine mitochondrial function. They hope to understand how faulty protein import affects the mitochondria and explore potential treatments to improve energy production and reduce cardiovascular risk.
A study found that longer duration of type 2 diabetes is associated with decreased brain structure and increased white matter hyperintensities. Despite this, cognition was not affected, highlighting the need for early screening for cognitive disorders in diabetic patients.
A Hong Kong study of 1.5 million people found that young-onset type 2 diabetes is associated with higher rates of hospital stays for mental health disorders. The study suggests that addressing mental health needs may be crucial in reducing hospitalization rates for young adults with type 2 diabetes.
A study published in Stroke found significant disparities in stroke risk factors between Black and non-Black adults. However, after one year of intensive medical intervention, some risk factors were reduced in Black adults.
The American College of Physicians recommends starting colorectal cancer screening at age 50 for asymptomatic adults with average risk. The guideline aims to balance benefits and harms of screening in this population. Screening in younger adults may not offer significant net benefit due to lower incidence rates.
A world-first study from the University of South Australia exposes the real weight gains of everyday Australians, finding that weight fluctuates throughout the year. The study highlights the importance of targeting temporal hot spots to curb unhealthy weight fluctuations and prevent unwanted weight gain.
Researchers found a genetic link that explains how certain individuals store fat at the abdomen but remain protected from type 2 diabetes. This discovery could pave the way for personalized medicine, tailoring treatments to individual genetic variations.
A study by I.R.C.C.S. Neuromed found that high consumption of ultra-processed foods significantly increases mortality risk among people with type 2 diabetes. Even those following a Mediterranean diet are at increased risk if ultra-processed foods account for a large share of their diet.
A new study found that snacking on high-quality foods can improve blood fat and insulin responses, while late-night snacking may have unfavorable effects. The researchers analyzed data from over 1,000 people in the UK and found no association between snack frequency or calories consumed and health measures.
A randomized controlled study found that participants who restricted their daily eating to between noon and 8 p.m. lost more weight and showed similar improvements in blood sugar levels compared to those on a calorie-restricted diet.
A program integrated community health workers into patient outreach to improve health, doubling annual visits to older adults with type 2 diabetes and dementia. The program resulted in a 17% reduction in hospital admissions and an 11% decline in emergency room visits among homebound patients.
A combination of Lactobacillus acidophilus and Lacticaseibacillus rhamnosus strains successfully inhibited the production of superantigens causing toxic shock syndrome. Probiotics may also prevent growth of Staphylococcus aureus, a virulent strain that produces proteins triggering the disease.
A study of over 100,000 participants found that eating breakfast late may increase the risk of developing type 2 diabetes. The research suggests that a first meal before 8 am and an early dinner may help reduce this risk.
A comprehensive review of biochemical markers for bone fragility in diabetes identifies low bone turnover and alterations in bone quality as key factors. The study suggests that glycemic control, AGEs, and serum IGF-1 may have predictive value for fracture risk in patients with diabetes.
A team of researchers has discovered a plant molecule that acts in the brain and improves blood sugar regulation. The dahlia extract was shown to considerably improve blood sugar regulation in preclinical trials and clinical studies, offering new hope for people with prediabetes or type 2 diabetes.
Researchers at UC Berkeley discovered that deep-sleep brain waves can regulate the body's sensitivity to insulin, improving blood sugar control. The study found that synchronized brain waves during deep sleep predict next-day glucose control, even after controlling for other factors.
Researchers found that aerobic exercise combined with weightlifting, afternoon exercise, and post-meal exercise can provide better glucose control; no weight loss required to see benefits. More movement is generally better for insulin sensitivity.
A large study published in the Journal of Clinical Endocrinology & Metabolism has found that moderate to light alcohol consumption does not protect against obesity and type 2 diabetes. The research, which analyzed data from over 408,000 participants, confirmed that heavy drinking increases measures of obesity and risk of type 2 diabetes.
A 12-year study by Pennington Biomedical researchers found that metabolic surgery provides better results, less regression, compared to medical or lifestyle intervention for patients with class 1 obesity. The study showed significant improvements in glycemic control and weight loss, with high rates of diabetes remission.
A new study found that higher doses of oral semaglutide improved regulation of blood sugar levels and weight loss compared to lower doses. Participants who received the 25mg and 50mg doses lost an average of 17.5 pounds, nearly twice as much weight loss as those who took the lowest dose.
Once-weekly Icodec demonstrated superior HbA1c reduction compared to once-daily Degludec after 26 weeks, but no difference was found in weight change. However, Icodec showed a higher rate of combined level two or three hypoglycemic events
The global diabetes crisis is accelerating due to widening inequity, with structural racism and geographic disparities exacerbating the problem. The new Series projects that over 1.3 billion people will live with diabetes by 2050, with marginalized communities facing reduced access to care and worse health outcomes.
A recent review article highlights how metformin increases miRNA let-7 levels in the liver, reducing hepatic glucose production. Additionally, it activates glucose conversion to lactate and acetate in the intestine, establishing a crosstalk between gut and liver that contributes to its antidiabetic effects.
The global prevalence of diabetes is expected to more than double from 6.1% to 12.8% by 2050, with every country experiencing an increase. The study found that high body mass index and dietary risks are primary contributors to type 2 diabetes.
A case series study demonstrated that a whole-food, plant-predominant dietary pattern and standard medical treatment can successfully achieve type 2 diabetes remission in 37 percent of patients. The study contributes novel information on the feasibility of achieving remission simply by eating healthy food.
A study found that people with a history of gestational diabetes are more likely to develop type 2 diabetes within nine years after delivery, particularly in Black and Hispanic women. Regular diabetes screenings in the early postpartum period can alter disease progression and improve control.
Researchers have found a hidden mechanism connecting cancer and diabetes, where cancer cells don't respond well to insulin, leading to faster cancer growth. Insulin resistance can also cause muscle loss and strength decline in cancer patients.
A new study suggests that eating more calories earlier in the day may improve metabolic health by reducing blood sugar fluctuations and inflammation. The study found that participants who followed an early time-restricted feeding pattern experienced a decrease in time above normal blood glucose levels, thereby improving metabolic health.
A review of studies found that reducing meal frequency and cutting out late-night snacks can improve insulin resistance, brain health, and glycemic control. This approach may also help regulate appetite hormones and reduce calorie intake, ultimately staving off obesity and metabolic disorders.
Researchers have identified a number of candidate genes that may drive the development of conditions like Type 2 Diabetes. The study found that proteins such as PCSK1, SUR1 and GLUT2 play a role in calcium ion dynamics and insulin secretion.
Studies found that low birthweight is independently linked to an increased risk of type 2 diabetes, with younger age at diagnosis and fewer comorbidities. Lower birthweight was also associated with a higher use of diabetes drugs and more severe hypertension.
Recent studies show that continuous glucose monitoring (CGM) is effective in improving glycemic control, reducing hypoglycemia risk, and increasing access to diabetes technologies. The technology has the potential to replace self-monitoring of blood glucose for insulin-requiring patients and become a standard for managing Type 2 Diabetes.
Researchers identified 10 genomic regions associated with insulin resistance after a meal, including a gene that affects glucose transport into cells. The study suggests targeted interventions may be possible in preventing type 2 diabetes.
A new study published in Nature Genetics sheds light on how humans maintain healthy blood sugar levels after meals and how the process goes wrong in type 2 diabetes. The findings could help inform future treatments of the condition, which affects over 460 million people worldwide.
A study of over 55,000 people identified new genetic variants associated with insulin resistance after eating, which may help inform future treatments of type 2 diabetes. The discovery highlights the importance of understanding how glucose regulation works in the body, particularly in the fed state.
The new scientific statement highlights the importance of identifying the root cause of pediatric cardiomyopathy to develop effective treatment strategies. Genetic testing is recommended for all children with cardiomyopathy, which may lead to financial and emotional cost savings.
A new randomized controlled trial found that taking metformin after testing positive for SARS-CoV-2 reduces the risk of developing long COVID by 40%. The study, published in The Lancet Infectious Diseases, involved over 1,100 patients and showed metformin prevented over 40% of cases of long COVID over a 10-month follow-up period.
Researchers in Austria found that one in three patients with Type 2 diabetes stopped treatment and monitoring for at least a year, resulting in higher mortality rates. This group had a significantly higher mortality rate compared to those who regularly accessed care.
A large-scale registry study found that older autistic adults have a significantly higher risk of injury, especially self-inflicted, and physical conditions such as type 2 diabetes and anaemia. Autistic individuals had a seven-fold risk of self-harm compared to non-autistic people.
A new study found that most adults with Type 2 diabetes in Alabama Medicaid did not receive follow-up healthcare within the recommended two-week period after a heart failure hospitalization. African American and Hispanic adults were particularly affected, with worse follow-up care compared to white adults.
Researchers at the University of Gothenburg found that semaglutide, a diabetes medication, significantly reduced alcohol intake and relapse-like drinking in rats. This study suggests that semaglutide may be effective in treating alcohol dependence, particularly for individuals with both obesity and diabetes.
Research shows higher physical activity levels can lower type 2 diabetes risk in people with high genetic risk. Regular exercise, especially moderate- to vigorous-intensity activities, was associated with a 74% lower risk of developing the condition.
Researchers discovered tirzepatide's unique ability to activate both GLP-1 and GIP receptors, leading to increased insulin secretion. This finding validates the potential of multi-receptor agonists for treating metabolic diseases.
Researchers discovered that tirzepatide stimulates insulin secretion in human pancreatic islets through the GIP receptor. This finding contrasts with previous studies in mice, which showed that tirzepatide primarily stimulated insulin secretion via the GLP-1 receptor.
A University of Virginia-led study challenges traditional understanding of associative polymers' behavior, revealing that reversible bonds slow down polymer movement without creating a rubbery network. This discovery has implications for materials used in sustainability, health, and engineering applications.
A new study published in the Journal of the American Heart Association found that elevated levels of two protein biomarkers associated with heart damage were linked to undetected or symptomless cardiovascular disease in adults with Type 2 diabetes. The study analyzed health information and blood samples from over 10,300 adults and foun...
A new American Heart Association scientific statement highlights the disproportionate burden of cardiovascular disease on AI/AN women. The study reveals that more than 60% of these women have suboptimal heart health when pregnant, increasing their risk of heart disease later in life.
Researchers at UBC Okanagan found that a low-carb breakfast can significantly reduce blood sugar swings and improve glucose control. Participants who followed a low-carb breakfast plan showed lower glycemic variability and some were able to reduce their glucose-lowering medication.
Researchers have discovered molecules in 3,000 diabetic patients that could help predict and monitor disease progression. The study identified 20 biomarkers associated with rapid disease progression, including a protein called NogoR.
Researchers found that participants who were physically active in the afternoon had greater reductions in blood sugar than those most active at other times of day. This study suggests timing of activity may be important for managing blood glucose levels.
A new method of analysis flags impaired glucose homeostasis (IGH) in 20% of 'healthy' participants using continuous glucose monitors. This finding has significant implications for early detection and prevention of Type 2 diabetes, with the potential to impact millions worldwide.
A recent study published in Diabetologia found an association between prediabetes and developing dementia in later life. The risk of dementia increases the earlier a person develops type 2 diabetes. Preventing progression from prediabetic state to diabetes diagnosis will lead to a substantial reduction in future dementia cases.
A new study from the University of South Australia shows that the Mediterranean diet is not only good for health but also for your weekly budget. Compared to the typical Australian Western diet, the Mediterranean diet costs less, with a family of four saving $28 per week and nearly $1500 per year
A randomized trial found that very low carbohydrate diets led to greater improvements in systolic blood pressure, glycemic control, and weight compared to the DASH diet. The addition of extra support did not have a statistically significant effect on outcomes.
Researchers have developed biodegradable hollow nanoscavengers that target reactive oxygen species to restore liver function and reverse insulin resistance in human liver cells and diabetic mice. This innovative approach offers a promising pathway toward long-term treatment of type 2 diabetes and other metabolic diseases.
A new study assesses racial bias in type 2 diabetes risk prediction algorithms. It finds significant disparities between US-based risk scores for non-Hispanic Blacks and non-Hispanic Whites.