Articles tagged with Type 2 Diabetes
Researchers in Austria found that one in three patients with Type 2 diabetes stopped treatment and monitoring for at least a year, resulting in higher mortality rates. This group had a significantly higher mortality rate compared to those who regularly accessed care.
A large-scale registry study found that older autistic adults have a significantly higher risk of injury, especially self-inflicted, and physical conditions such as type 2 diabetes and anaemia. Autistic individuals had a seven-fold risk of self-harm compared to non-autistic people.
A new study found that most adults with Type 2 diabetes in Alabama Medicaid did not receive follow-up healthcare within the recommended two-week period after a heart failure hospitalization. African American and Hispanic adults were particularly affected, with worse follow-up care compared to white adults.
Researchers at the University of Gothenburg found that semaglutide, a diabetes medication, significantly reduced alcohol intake and relapse-like drinking in rats. This study suggests that semaglutide may be effective in treating alcohol dependence, particularly for individuals with both obesity and diabetes.
Research shows higher physical activity levels can lower type 2 diabetes risk in people with high genetic risk. Regular exercise, especially moderate- to vigorous-intensity activities, was associated with a 74% lower risk of developing the condition.
Researchers discovered tirzepatide's unique ability to activate both GLP-1 and GIP receptors, leading to increased insulin secretion. This finding validates the potential of multi-receptor agonists for treating metabolic diseases.
Researchers discovered that tirzepatide stimulates insulin secretion in human pancreatic islets through the GIP receptor. This finding contrasts with previous studies in mice, which showed that tirzepatide primarily stimulated insulin secretion via the GLP-1 receptor.
A University of Virginia-led study challenges traditional understanding of associative polymers' behavior, revealing that reversible bonds slow down polymer movement without creating a rubbery network. This discovery has implications for materials used in sustainability, health, and engineering applications.
A new study published in the Journal of the American Heart Association found that elevated levels of two protein biomarkers associated with heart damage were linked to undetected or symptomless cardiovascular disease in adults with Type 2 diabetes. The study analyzed health information and blood samples from over 10,300 adults and foun...
A new American Heart Association scientific statement highlights the disproportionate burden of cardiovascular disease on AI/AN women. The study reveals that more than 60% of these women have suboptimal heart health when pregnant, increasing their risk of heart disease later in life.
Researchers at UBC Okanagan found that a low-carb breakfast can significantly reduce blood sugar swings and improve glucose control. Participants who followed a low-carb breakfast plan showed lower glycemic variability and some were able to reduce their glucose-lowering medication.
Researchers have discovered molecules in 3,000 diabetic patients that could help predict and monitor disease progression. The study identified 20 biomarkers associated with rapid disease progression, including a protein called NogoR.
Researchers found that participants who were physically active in the afternoon had greater reductions in blood sugar than those most active at other times of day. This study suggests timing of activity may be important for managing blood glucose levels.
A new method of analysis flags impaired glucose homeostasis (IGH) in 20% of 'healthy' participants using continuous glucose monitors. This finding has significant implications for early detection and prevention of Type 2 diabetes, with the potential to impact millions worldwide.
A recent study published in Diabetologia found an association between prediabetes and developing dementia in later life. The risk of dementia increases the earlier a person develops type 2 diabetes. Preventing progression from prediabetic state to diabetes diagnosis will lead to a substantial reduction in future dementia cases.
A randomized trial found that very low carbohydrate diets led to greater improvements in systolic blood pressure, glycemic control, and weight compared to the DASH diet. The addition of extra support did not have a statistically significant effect on outcomes.
A new study from the University of South Australia shows that the Mediterranean diet is not only good for health but also for your weekly budget. Compared to the typical Australian Western diet, the Mediterranean diet costs less, with a family of four saving $28 per week and nearly $1500 per year
Researchers have developed biodegradable hollow nanoscavengers that target reactive oxygen species to restore liver function and reverse insulin resistance in human liver cells and diabetic mice. This innovative approach offers a promising pathway toward long-term treatment of type 2 diabetes and other metabolic diseases.
A new study assesses racial bias in type 2 diabetes risk prediction algorithms. It finds significant disparities between US-based risk scores for non-Hispanic Blacks and non-Hispanic Whites.
Researchers developed a computational approach to predict diabetic kidney disease using DNA methylation markers from a blood sample. The model can use this information to assess current and future kidney function, enabling early detection and prevention of kidney disease in people with type 2 diabetes.
The new FRAXplus beta version offers a more user-friendly platform to refine risk factor information, allowing clinicians to explore the impact on individual patients. The tool provides helpful features such as saved data and export options to facilitate sharing.
A retrospective cohort study of U.S. veterans found that adding a GLP1 receptor agonist to diabetes treatment reduced the risk of major adverse cardiovascular events and heart failure hospitalization by about 20% compared to DPP4 inhibitors. The study's findings will aid clinicians in choosing a diabetes drug regimen for older patients.
A recent study published in PLOS ONE found that patients with Type 2 diabetes who have full chewing function have significantly lower blood glucose levels compared to those with impaired chewing ability. The research highlights the importance of dental care and occlusal function in managing blood sugar levels.
Research highlights unique effects of Asian American subgroups on heart disease and Type 2 diabetes risk. Variations in cardiovascular risk among Asian Americans indicate the need for individual subgroup data to better understand health risks.
A new study published in JMIR Diabetes found that Fitterfly's diabetes digital therapeutics program improved glycemic control and weight management in participants with type 2 diabetes. The 90-day program led to significant reductions in hemoglobin A1c levels and body weight.
Recent cluster analyses identify novel risk stratification concepts to better implement precision medicine in clinical practice. Metabolically unhealthy individuals, regardless of weight, face a higher CVD risk compared to obese, metabolically healthy peers.
A pilot study found that high-dose tadalafil improved metabolic control and reduced hemoglobin A1c levels by 2.50 mmol/mol in patients with well-controlled type 2 diabetes. The treatment also showed increased blood flow, liver values, and metabolism.
Researchers at West Virginia University found that bariatric surgery significantly reduces the risk of major cardiovascular events and death in patients with NAFLD. The study included 9,374 adult patients with NAFLD and obesity, who underwent either Roux-en-Y gastric bypass or sleeve gastrectomy.
Researchers at Lund University have identified five subgroups of type 2 diabetes in India, characterized by genetic differences and varying levels of severity. The study suggests that early life undernutrition may contribute to the development of type 2 diabetes in India, while vitamin B12 deficiency is also a significant factor.
A new endoscopic procedure has shown promising results in eliminating the need for insulin in type 2 diabetes patients. In a preliminary study, 86% of participants maintained good glycemic control without insulin for a year after undergoing the procedure, suggesting it may reverse the body's resistance to its own insulin.
Researchers developed a novel biomarker-based indicator of the Mediterranean diet, which incorporates levels of fatty acids and carotenoids in blood. The study found that those with higher scores had lower risk of developing type 2 diabetes, suggesting a stronger link than self-reported diet adherence.
A new study found that individuals who experienced childhood adversity, such as poverty, illness, or death in the family, are at higher risk of developing type 2 diabetes in early adulthood. The study, conducted on a large population-based cohort, reveals that these adverse experiences can lead to increased inflammation, insulin resist...
Researchers found that women with prediabetes after pregnancy had aberrations in their early pregnancy blood serum metabolomic profile, including higher concentrations of small HDL particles. These metabolic changes predicted prediabetes at postpartum and were associated with increased risk of type 2 diabetes.
Replacing sugary drinks with healthier options like coffee, tea, and plain water is associated with lower rates of early death among adults with type 2 diabetes. The study found that increasing consumption of these beverages was linked to a lower risk of cardiovascular disease-related mortality.
A new study found that high consumption of sugar-sweetened beverages was associated with an elevated risk of premature death and incidence of cardiovascular disease among people with type 2 diabetes. Drinking healthier beverages like coffee, tea, and plain water was linked to lower risk of dying prematurely.
A $4.1 million NIH grant will help Montefiore Einstein researchers identify factors besides obesity that contribute to high rates of type 2 diabetes among children in the Bronx. The study aims to assess biological and social risk factors for youth-onset T2D, including food and housing insecurity.
A new study published in PLOS Medicine found that the sugary drink tax in Oakland reduced purchases by 26.8%, leading to improved health and significant cost savings. The researchers estimated that consuming fewer SSBs added 94 quality-adjusted life-years per 10,000 residents and saved the city over $100,000 in healthcare costs.
A qualitative case series study provides the first published examples of medication deprescribing protocols for patients with type 2 diabetes. The results highlight the importance of de-escalating glucose-lowering medications when patients achieve remission through lifestyle medicine interventions.
A study by Tufts University researchers estimates that poor diet contributed to over 14.1 million cases of type 2 diabetes in 2018, accounting for 70% of new diagnoses globally. The analysis found that diets rich in refined grains and processed meat had the greatest impact on type 2 diabetes incidence.
A new study from Johns Hopkins Bloomberg School of Public Health suggests that chronic health conditions such as type 2 diabetes and asthma are greatly undertreated in the US jail and prison population. The researchers found significant disparities in treatment rates compared to the general US population, with incarcerated individuals ...
Researchers found Tai Chi Chuan improved global cognition and physical markers in individuals with Type 2 diabetes and mild cognitive impairment. After 36 weeks, the Tai Chi Chuan group showed a significant average improvement of 3.29 points on the Montreal Cognitive Assessment score compared to the baseline.
The new American Heart Association scientific statement emphasizes the importance of including non-biological factors and social determinants in CVD risk assessment for women. These factors include economic stability, neighborhood safety, education level, and access to quality healthcare, which disproportionately affect women from dive...
Researchers used DNA methylation data alongside traditional risk factors to improve prediction accuracy for type 2 diabetes. The study, involving over 14,600 participants, found that the new approach correctly predicted an extra 449 individuals, leading to potential preventative measures and reduced health burden.
A fasting diet that focuses on early eating has been shown to reduce the risk markers of type 2 diabetes. Researchers found that participants who followed a time-restricted, intermittent fasting diet experienced greater tolerance to glucose and reduced blood lipids compared to those on a daily, low-calorie diet.
A team of researchers from Ohio University discovered that CIDEC protein improves vascular and metabolic dysfunction, reducing insulin resistance and lipid levels in high-fat diet-induced mice. The study contributes to understanding the role of the vascular endothelium in regulating systemic metabolism.
Researchers aim to understand the allure of highly processed foods, which make up 58% of US calories. By studying their processing and added ingredients, they hope to identify underlying variables driving consumption.
Two new subtypes of insulin-producing beta cells, ß <sub> HI </sub> and ß <sub> LO </sub>, have been identified with distinct characteristics. The study suggests epigenetic dosage as a driving force behind the decision of ß cells to become these subtypes, offering a new target for potential diabetes treatments.
Research highlights that intensive behavioral weight loss programs significantly reduce cardiovascular disease and Type 2 diabetes risk factors, which persist for at least five years. Participants who lost weight through such programs had lower risk factors compared to those in less intensive or no weight loss programs.
A study of 32 Black patients with type 2 diabetes found that humanistic communication, family involvement, and clear medical information are crucial for effective shared decision making. The research team offers recommendations to improve SDM in safety-net primary care settings.
A new study by UC San Francisco found that taxes on sugary drinks lower the risk of gestational diabetes, unhealthy weight gain, and small-for-gestational-age babies. The study analyzed over 5 million pregnant women and found a significant reduction in these health risks.
A new study suggests that age, not weight, should be used to screen for diabetes, capturing the greatest number of people in all racial and ethnic groups. The approach identifies the greatest proportion of adults with prediabetes and diabetes and maximizes equity across racial and ethnic groups.
Exercise training after bariatric surgery alters brain networks associated with food intake and energy regulation. The study found that exercise increased connectivity between the hypothalamus and sensory areas, while decreasing links to the default mode network and salience network.
A study published in Redox Biology found that decreased expression of mitochondrial aminoacyl-tRNA synthetases leads to downregulation of OXPHOS subunits in type 2 diabetic muscle. Nitric oxide production is also increased, which could be used as a method for diagnosing the disease.
The study found that vaccination significantly reduces the risk of long COVID, while factors such as being overweight, female, smoker, or over 40 increase the likelihood of developing the condition. Vaccination halves people's risk of developing long Covid
New research reveals coffee consumption may help reduce the risk of type 2 diabetes by lowering inflammatory biomarkers in the body. A study published in Clinical Nutrition found that a one cup per day increase in coffee consumption was associated with a 4-6% lower risk of T2D.
A new study reveals that the SPUR tool, developed by Kingston University and Observia, can accurately predict hospital admissions and early readmissions in people with Type 2 Diabetes. The tool has been found to be effective in reducing hospital admissions and improving patient outcomes.
A new study by Weill Cornell Medicine investigators found four distinct types of beta cells in the pancreas, with cluster 1 beta cells producing more insulin than others and appearing better able to metabolize sugar. The loss of these high-functioning beta cells may contribute to type 2 diabetes development.
Research suggests that high blood caffeine levels are associated with lower weight and body fat, as well as a reduced risk of type 2 diabetes. The study used Mendelian randomisation to explore the potential effects of caffeine on these outcomes.
A phase two trial found that exenatide significantly reduced brain pressure and monthly headaches in seven patients with Idiopathic Intercranial Hypertension (IIH). The study showed a rapid action of the drug, with results indicating significant reductions in brain pressure and headache days compared to the placebo arm.
A new study suggests that pregnant women who have dimmed lights and screens for three hours before sleep are less likely to develop gestational diabetes. Dim light exposure before bedtime may help regulate glucose levels, reducing the risk of this common pregnancy complication.