Articles tagged with Type 2 Diabetes
Researchers developed a computational approach to predict diabetic kidney disease using DNA methylation markers from a blood sample. The model can use this information to assess current and future kidney function, enabling early detection and prevention of kidney disease in people with type 2 diabetes.
The new FRAXplus beta version offers a more user-friendly platform to refine risk factor information, allowing clinicians to explore the impact on individual patients. The tool provides helpful features such as saved data and export options to facilitate sharing.
A retrospective cohort study of U.S. veterans found that adding a GLP1 receptor agonist to diabetes treatment reduced the risk of major adverse cardiovascular events and heart failure hospitalization by about 20% compared to DPP4 inhibitors. The study's findings will aid clinicians in choosing a diabetes drug regimen for older patients.
A recent study published in PLOS ONE found that patients with Type 2 diabetes who have full chewing function have significantly lower blood glucose levels compared to those with impaired chewing ability. The research highlights the importance of dental care and occlusal function in managing blood sugar levels.
Research highlights unique effects of Asian American subgroups on heart disease and Type 2 diabetes risk. Variations in cardiovascular risk among Asian Americans indicate the need for individual subgroup data to better understand health risks.
A new study published in JMIR Diabetes found that Fitterfly's diabetes digital therapeutics program improved glycemic control and weight management in participants with type 2 diabetes. The 90-day program led to significant reductions in hemoglobin A1c levels and body weight.
Recent cluster analyses identify novel risk stratification concepts to better implement precision medicine in clinical practice. Metabolically unhealthy individuals, regardless of weight, face a higher CVD risk compared to obese, metabolically healthy peers.
A pilot study found that high-dose tadalafil improved metabolic control and reduced hemoglobin A1c levels by 2.50 mmol/mol in patients with well-controlled type 2 diabetes. The treatment also showed increased blood flow, liver values, and metabolism.
Researchers at West Virginia University found that bariatric surgery significantly reduces the risk of major cardiovascular events and death in patients with NAFLD. The study included 9,374 adult patients with NAFLD and obesity, who underwent either Roux-en-Y gastric bypass or sleeve gastrectomy.
Researchers at Lund University have identified five subgroups of type 2 diabetes in India, characterized by genetic differences and varying levels of severity. The study suggests that early life undernutrition may contribute to the development of type 2 diabetes in India, while vitamin B12 deficiency is also a significant factor.
A new endoscopic procedure has shown promising results in eliminating the need for insulin in type 2 diabetes patients. In a preliminary study, 86% of participants maintained good glycemic control without insulin for a year after undergoing the procedure, suggesting it may reverse the body's resistance to its own insulin.
Researchers developed a novel biomarker-based indicator of the Mediterranean diet, which incorporates levels of fatty acids and carotenoids in blood. The study found that those with higher scores had lower risk of developing type 2 diabetes, suggesting a stronger link than self-reported diet adherence.
A new study found that individuals who experienced childhood adversity, such as poverty, illness, or death in the family, are at higher risk of developing type 2 diabetes in early adulthood. The study, conducted on a large population-based cohort, reveals that these adverse experiences can lead to increased inflammation, insulin resist...
Researchers found that women with prediabetes after pregnancy had aberrations in their early pregnancy blood serum metabolomic profile, including higher concentrations of small HDL particles. These metabolic changes predicted prediabetes at postpartum and were associated with increased risk of type 2 diabetes.
Replacing sugary drinks with healthier options like coffee, tea, and plain water is associated with lower rates of early death among adults with type 2 diabetes. The study found that increasing consumption of these beverages was linked to a lower risk of cardiovascular disease-related mortality.
A new study found that high consumption of sugar-sweetened beverages was associated with an elevated risk of premature death and incidence of cardiovascular disease among people with type 2 diabetes. Drinking healthier beverages like coffee, tea, and plain water was linked to lower risk of dying prematurely.
A $4.1 million NIH grant will help Montefiore Einstein researchers identify factors besides obesity that contribute to high rates of type 2 diabetes among children in the Bronx. The study aims to assess biological and social risk factors for youth-onset T2D, including food and housing insecurity.
A new study published in PLOS Medicine found that the sugary drink tax in Oakland reduced purchases by 26.8%, leading to improved health and significant cost savings. The researchers estimated that consuming fewer SSBs added 94 quality-adjusted life-years per 10,000 residents and saved the city over $100,000 in healthcare costs.
A qualitative case series study provides the first published examples of medication deprescribing protocols for patients with type 2 diabetes. The results highlight the importance of de-escalating glucose-lowering medications when patients achieve remission through lifestyle medicine interventions.
A study by Tufts University researchers estimates that poor diet contributed to over 14.1 million cases of type 2 diabetes in 2018, accounting for 70% of new diagnoses globally. The analysis found that diets rich in refined grains and processed meat had the greatest impact on type 2 diabetes incidence.
A new study from Johns Hopkins Bloomberg School of Public Health suggests that chronic health conditions such as type 2 diabetes and asthma are greatly undertreated in the US jail and prison population. The researchers found significant disparities in treatment rates compared to the general US population, with incarcerated individuals ...
Researchers found Tai Chi Chuan improved global cognition and physical markers in individuals with Type 2 diabetes and mild cognitive impairment. After 36 weeks, the Tai Chi Chuan group showed a significant average improvement of 3.29 points on the Montreal Cognitive Assessment score compared to the baseline.
The new American Heart Association scientific statement emphasizes the importance of including non-biological factors and social determinants in CVD risk assessment for women. These factors include economic stability, neighborhood safety, education level, and access to quality healthcare, which disproportionately affect women from dive...
Researchers used DNA methylation data alongside traditional risk factors to improve prediction accuracy for type 2 diabetes. The study, involving over 14,600 participants, found that the new approach correctly predicted an extra 449 individuals, leading to potential preventative measures and reduced health burden.
A fasting diet that focuses on early eating has been shown to reduce the risk markers of type 2 diabetes. Researchers found that participants who followed a time-restricted, intermittent fasting diet experienced greater tolerance to glucose and reduced blood lipids compared to those on a daily, low-calorie diet.
A team of researchers from Ohio University discovered that CIDEC protein improves vascular and metabolic dysfunction, reducing insulin resistance and lipid levels in high-fat diet-induced mice. The study contributes to understanding the role of the vascular endothelium in regulating systemic metabolism.
Researchers aim to understand the allure of highly processed foods, which make up 58% of US calories. By studying their processing and added ingredients, they hope to identify underlying variables driving consumption.
Two new subtypes of insulin-producing beta cells, ß <sub> HI </sub> and ß <sub> LO </sub>, have been identified with distinct characteristics. The study suggests epigenetic dosage as a driving force behind the decision of ß cells to become these subtypes, offering a new target for potential diabetes treatments.
Research highlights that intensive behavioral weight loss programs significantly reduce cardiovascular disease and Type 2 diabetes risk factors, which persist for at least five years. Participants who lost weight through such programs had lower risk factors compared to those in less intensive or no weight loss programs.
A study of 32 Black patients with type 2 diabetes found that humanistic communication, family involvement, and clear medical information are crucial for effective shared decision making. The research team offers recommendations to improve SDM in safety-net primary care settings.
A new study by UC San Francisco found that taxes on sugary drinks lower the risk of gestational diabetes, unhealthy weight gain, and small-for-gestational-age babies. The study analyzed over 5 million pregnant women and found a significant reduction in these health risks.
A new study suggests that age, not weight, should be used to screen for diabetes, capturing the greatest number of people in all racial and ethnic groups. The approach identifies the greatest proportion of adults with prediabetes and diabetes and maximizes equity across racial and ethnic groups.
Exercise training after bariatric surgery alters brain networks associated with food intake and energy regulation. The study found that exercise increased connectivity between the hypothalamus and sensory areas, while decreasing links to the default mode network and salience network.
A study published in Redox Biology found that decreased expression of mitochondrial aminoacyl-tRNA synthetases leads to downregulation of OXPHOS subunits in type 2 diabetic muscle. Nitric oxide production is also increased, which could be used as a method for diagnosing the disease.
The study found that vaccination significantly reduces the risk of long COVID, while factors such as being overweight, female, smoker, or over 40 increase the likelihood of developing the condition. Vaccination halves people's risk of developing long Covid
New research reveals coffee consumption may help reduce the risk of type 2 diabetes by lowering inflammatory biomarkers in the body. A study published in Clinical Nutrition found that a one cup per day increase in coffee consumption was associated with a 4-6% lower risk of T2D.
A new study reveals that the SPUR tool, developed by Kingston University and Observia, can accurately predict hospital admissions and early readmissions in people with Type 2 Diabetes. The tool has been found to be effective in reducing hospital admissions and improving patient outcomes.
A new study by Weill Cornell Medicine investigators found four distinct types of beta cells in the pancreas, with cluster 1 beta cells producing more insulin than others and appearing better able to metabolize sugar. The loss of these high-functioning beta cells may contribute to type 2 diabetes development.
Research suggests that high blood caffeine levels are associated with lower weight and body fat, as well as a reduced risk of type 2 diabetes. The study used Mendelian randomisation to explore the potential effects of caffeine on these outcomes.
A phase two trial found that exenatide significantly reduced brain pressure and monthly headaches in seven patients with Idiopathic Intercranial Hypertension (IIH). The study showed a rapid action of the drug, with results indicating significant reductions in brain pressure and headache days compared to the placebo arm.
A new study suggests that pregnant women who have dimmed lights and screens for three hours before sleep are less likely to develop gestational diabetes. Dim light exposure before bedtime may help regulate glucose levels, reducing the risk of this common pregnancy complication.
A new study by Massachusetts General Hospital found that genetic and socioeconomic factors interact to increase the risk of type 2 diabetes and obesity. The study's findings suggest that interventions to improve socioeconomic deprivation may decrease metabolic diseases at the individual and community levels.
A recent study found that the incidence rates of type 1 and type 2 diabetes continue to rise in children and young adults in the US. Non-Hispanic Black and Hispanic youth were particularly affected, with higher incidence rates compared to non-Hispanic white peers.
Two studies found that adults with high cardiovascular health scores tend to live longer lives free of major chronic diseases. The research highlights the importance of maintaining ideal cardiovascular health to delay onset of age-related diseases, allowing individuals to enjoy life in their years as well as their years in life.
A retrospective cohort study found that sodium-glucose cotransporter 2 inhibitors (SGLT2i) significantly reduced the risk of end-stage renal disease, obstructive airway disease, and pneumonia in patients with type 2 diabetes. SGLT2i may be a better alternative to dipeptidyl peptidase-4 inhibitors for extra-glycaemic protection.
A new study found that a plant-based low-carbohydrate diet is associated with lower all-cause mortality among people with type 2 diabetes. The study, published in Diabetes Care, analyzed data from over 7,000 participants and found that such diets reduced mortality by 24%.
A new study published in Diabetologia found that childhood obesity is associated with a higher risk of four out of the five recently proposed subtypes of adult-onset diabetes. The study used Mendelian randomization to investigate the link between childhood body size and the risk of different diabetes subtypes occurring in adults.
A study found that over 80% of American adults with type 2 diabetes meet the criteria to use GLP-1 RAs or SGLT2is, but only a small percentage are using them. The medications have a substantially higher cost than current first-line treatments, making it difficult for patients to access them.
A smartphone app-based cognitive behavioral therapy program lowered blood sugar levels and improved health behaviors in patients with diabetes. The study found a clear 'dose effect,' where participants completing more lessons saw greater benefits.
A phase 3 clinical trial found that oral empagliflozin provided clinically meaningful and statistically significant improvements in glycemic control in young people with type 2 diabetes. The study demonstrated the safety and efficacy of empagliflozin in this population, while linagliptin did not show significant effects.
A recent study published in the Journal of Clinical Investigation found that PAX5 is strongly associated with impaired insulin secretion in type 2 diabetes. The research team identified 94 previously known genes and discovered many new genes differently expressed in individuals with type 2 diabetes.
A new study found that people with newly diagnosed type 2 diabetes who took pioglitazone were less likely to develop dementia, with reduced risks of 16% and 54% among those with a history of ischemic heart disease or stroke. The benefit increased with longer drug use periods.
Acylated anthocyanins found in purple potatoes, sweet potatoes, and carrots have been shown to reduce type 2 diabetes risk by affecting glucose transporters and enzymes involved in metabolism. These compounds also maintain gut microbiota homeostasis and suppress pro-inflammatory pathways.
Researchers found a significant increase in new-onset diabetes after COVID-19 infection, with vaccination prior to infection showing protective effects. The study suggests that COVID-19 infection could be acting as a disease accelerator, amplifying risk for diabetes diagnosis.
A recent study found that adults with type 1 diabetes are at a high risk of being overweight or obese, but only half receive lifestyle recommendations to manage their weight. The study also highlighted the importance of individualized patient education in improving weight management for these patients.
A new study found that pregnant individuals who give birth to large-for-gestational-age (LGA) babies are at a higher risk of developing prediabetes or Type 2 diabetes 10-14 years after childbirth. Researchers analyzed data from the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study, which revealed a significant association bet...
Researchers discovered microexons, short DNA sequences that play a vital role in insulin secretion and glucose homeostasis. The study found that genetic variants affecting microexon inclusion are linked to type-2 diabetes risk and fasting blood sugar levels.
Scientists have discovered that wrinkles in the cellular nucleus may be involved in common metabolic diseases such as diabetes and fatty liver disease. The new findings suggest that targeting these wrinkles could lead to novel treatments for non-alcoholic fatty liver disease, which affects 40% of people over age 70.
A large-scale genetic analysis identified microRNAs in human pancreatic cells strongly associated with type 2 diabetes. The study found specific microRNAs different in people with the condition, which may chart its course or inform drug therapies.
A new study published in the Proceedings of the National Academy of Sciences has identified 14 pancreatic islet miRNAs associated with human type 2 diabetes. The study used a large sample size of nearly 65 human pancreatic islets to uncover these miRNAs, revealing potential mechanisms for disease development and novel therapeutic targets.