Articles tagged with Type 2 Diabetes
A new poll found that 83% of older adults believe health insurers should cover medications to help people with obesity manage their weight. Nearly as many, 76%, also believe Medicare should cover these drugs, which are currently not covered under law.
Using metformin plus insulin to treat preexisting type 2 or gestational diabetes diagnosed early in pregnancy did not show a reduction in composite neonatal adverse outcomes. The study suggests that the effect of reducing large-for-gestational-age infant risk after adding metformin to insulin warrants further investigation.
A Northwestern University study found that nearly two-thirds of patients discontinue or change their medication within a year, highlighting the need for better understanding of barriers to treatment adherence. The high discontinuation rate for GLP-1 RAs may be due to gastrointestinal side effects.
A plant-based diet has been shown to reduce the risk of type 2 diabetes by 24%, with benefits attributed to improved metabolism and liver function. Additionally, healthy eating patterns were found to improve organ function, particularly in individuals with genetic predispositions or other risk factors.
A national food choice experiment found that labeling a meat-free and dairy-free food basket as 'vegan' or 'plant-based' leads to lower appeal, whereas labels like 'healthy' or 'sustainable' result in higher preference. This study suggests using these alternative labels can encourage healthier and more environmentally sustainable eatin...
Research shows that Australian children are at risk of excessive weight gain and declining fitness during school holidays. The two-year study found that body fat increased at a faster pace and aerobic fitness declined faster than in-school periods. Promoting physical activities during holidays could help address unhealthy weight gain.
A new study found no increased risk of major congenital malformations in infants exposed to second-line non-insulin antidiabetic medications during pregnancy compared to those treated with insulin. The study examined over 3.5 million pregnancies and provided reassurance on the safety of these medications for fetuses.
A phase 3 trial found that tirzepatide promotes additional weight loss and preserves metabolic health when continued, but discontinuation leads to significant weight regain. Researchers suggest chronic treatment may be necessary for sustained weight loss and improved cardiometabolic risk factors.
Researchers found that GLP-1 RAs significantly reduced the incidence of colorectal cancer in patients with diabetes, compared to those treated with other anti-diabetic drugs. The study's findings support the need for clinical trials to determine whether these medications could prevent one of the deadliest types of cancers.
A comprehensive study has linked a regulatory gene network and functional defects in insulin-producing pancreatic beta cells to Type 2 diabetes. The research provides a template for identifying additional early disease-driving events for Type 2 diabetes.
The UTHealth Houston School of Public Health offers a 12-month lifestyle program combining evidence-based nutrition education with culinary learning to support behavior change. Participants will attend in-person and virtual classes, including hands-on cooking lessons, physical activity guidance, and mindfulness education.
The international consensus report on precision diabetes medicine highlights significant advancements in prevention, diagnosis, treatment, and prognosis. The report also sheds light on knowledge gaps and provides a framework for future research.
According to a new study published in Annals of Internal Medicine, most adults who qualify for statin use for primary prevention are not receiving them. The study found that despite increased overall statin use over time, only 35% of eligible adults were taking statins between 2013 and 2018. The researchers suggest that innovative effo...
A research team led by USC's Abigail Horn used smartphone mobility data to find a strong correlation between location visits and diet-related diseases. The study reveals that physical food environments play a crucial role in shaping people's eating decisions, with environments like fast-food joints contributing to unhealthy choices.
Elevated blood glycerol levels are linked to increased TB disease severity in experimental models with Type 2 diabetes. The study identifies glycerol kinase as a crucial enzyme driving TB disease severity.
A pooled data analysis of 10 studies found that walking speeds above 4 km/hour are associated with a significantly lower risk of type 2 diabetes. For every 1 km increase in speed, the risk drops by 9%. Regular brisk walking may be an effective strategy to stave off the disease.
Researchers found that using doctor- and patient-oriented materials improved conversations about erectile dysfunction (ED) among Asian men with diabetes. The study suggests that these materials can encourage treatment of ED, particularly in cultures where sex is viewed as taboo.
The DAPPER study found that dapagliflozin 5mg daily reduced cardiovascular events, including cardiovascular death or hospitalization, in patients with chronic heart failure and type 2 diabetes. This was the first report to show this effect at a dose of 5mg.
A new hydrogel drug delivery system has been developed that can transform daily injections of diabetes and weight control drugs into once every four months. The system has shown promising potential in laboratory tests and could improve management of Type 2 diabetes, patient drug compliance, and long-term health outcomes.
A simulation study suggests that a soft drink tax in Germany would reduce sugar consumption and illness rates, including type 2 diabetes, resulting in significant financial savings. The estimated economic benefits of introducing such a tax range from 9.5 billion to 16 billion euros over the next two decades.
A tiered tax system incentivizes companies to reduce sugar content, leading to a significant reduction in sugar intake and medical costs. The study predicts that such a tax could prevent over 244,000 cases of type 2 diabetes and save €16.0 billion.
Research finds that poor nutrition contributes to both type 2 diabetes and mental health disorders like depression and anxiety. A balanced diet rich in fruits, vegetables, whole grains, lean protein, and low-fat dairy can reduce the risk of these conditions.
Social determinants like food insecurity and housing issues were linked to lower likelihoods of receiving diabetic retinopathy screening. The study highlights the importance of addressing barriers to care for promoting health equity.
A large Asian cohort study identified systolic blood pressure targets below 130 mmHg and diastolic targets between 80-89 mmHg as key to reducing cardiovascular mortality. The findings underscore the need for cautious blood pressure management in patients with diabetes.
Researchers analyzed FDA and patent records to find that manufacturers extended market exclusivity by filing additional patents after FDA approval and obtaining patents on delivery devices. This resulted in a median of 16 years of protection, surpassing other top-selling small-molecule drugs.
A new USC study identifies two metabolites that may predict which young Latino people are most likely to develop prediabetes. The research found that allylphenol sulfate and caprylic acid were the most predictive of prediabetes when combined with other risk factors.
Researchers are developing a bioengineered pancreas-like tissue using innovative biomaterials and engineered cells. The goal is to implant these cell-laden scaffolds into patients who need help managing their glucose levels.
A study of 54,000 participants found that diabetes was associated with an elevated risk of colorectal cancer. The association was attenuated for those who completed colonoscopies, highlighting the potential benefits of preventative screening.
A new study found that curtailing sleep by 90 minutes for six weeks increased insulin resistance in women, particularly postmenopausal women. Insulin resistance was also linked to an increased risk of developing type 2 diabetes.
Researchers found that people with overweight or obesity who took semaglutide for over 3 years had a 20% lower risk of heart attack, stroke, or death from cardiovascular disease. The study showed significant weight loss and improved cardiovascular outcomes in adults without diabetes.
A drug currently in clinical trials as a cancer therapy can also stimulate pancreatic beta cells to secrete insulin, revealing a new mechanism for insulin regulation in type 2 diabetes. The preclinical discovery provides a new chemical tool for probing the biology of diabetes and could lead to better treatments.
Researchers from Helmholtz Munich discovered that GIP decreases body weight by interacting with specific inhibitory neurons in the brain, offering a revolutionary approach to patients worldwide. The study reveals the underlying molecular mechanisms of GIPR:GLP-1R co-agonists and their potential as next-generation anti-obesity drugs.
A preclinical study by Weill Cornell Medicine researchers reveals that activating a pathway to promote cell division can expand insulin-producing cells without impairing their function. The study's findings support the concept that beta cell mass can be expanded without compromising function.
A large US study found that persistent tobacco use and prediabetes significantly increase the risk of stroke in young adults without other cardiovascular risk factors. Quitting smoking is crucial for preventing stroke and heart disease, especially among those with prediabetes.
Two preliminary studies presented at American Heart Association’s Scientific Sessions 2023 found a potential association between regular marijuana use and an increased risk of heart failure, heart attack, and stroke. Daily marijuana use was associated with incident heart failure in a study involving over 150,000 adults in the US.
Research highlights significantly higher heart attack death rates among American Indian and Alaska Native adults, particularly at younger ages. The study suggests that factors like limited healthcare access, socioeconomic conditions, and restricted health insurance coverage may contribute to these disparities.
A six-month produce prescription program improved hemoglobin A1c levels, indicating better blood sugar control. Participants also showed improved food security and nutrition security.
A new Cochrane review has found that human insulin can be stored at room temperature for up to six months without losing potency. This breakthrough research offers hope to millions of people living with diabetes in low- and middle-income countries, particularly those with limited access to refrigeration or healthcare.
A new study from Tulane University found that frequent salt consumption is associated with a higher risk of developing Type 2 diabetes. The study surveyed over 400,000 adults and found participants who regularly added salt had a 13% to 39% increased risk of developing the disease compared to those who never or rarely used salt.
Researchers at University of British Columbia find a direct link between high insulin levels and pancreatic cancer, highlighting the importance of keeping insulin levels within a healthy range. The study suggests that excessive insulin overstimulates pancreatic acinar cells, leading to inflammation and precancerous cell development.
A new study published in JAMA Network Open found time-restricted eating to be safe and effective for people with Type 2 diabetes, helping them lose weight and control blood sugar levels. Participants who followed the time-restricted eating plan had an easier time sticking to it than those on a calorie-reduced diet.
A six-month randomized clinical trial involving 75 adults with type 2 diabetes found that time-restricted eating was effective for weight loss. This novel dietary approach lowered hemoglobin A1c levels without calorie counting, offering potential for improved blood sugar management and overall health.
A new study published in The American Journal of Clinical Nutrition found that consuming more red meat is associated with a higher risk of developing type 2 diabetes. Replacing red meat with plant-based protein sources like nuts and legumes may reduce this risk.
A large Danish study finds that migrants typically receive inferior care for type 2 diabetes, particularly in monitoring and controlling biomarkers. Migrants from Somalia face the worst care, with elevated risks across all indicators.
A new study by Klick Labs reveals that AI technology can screen for Type 2 diabetes using six to 10 seconds of a person's voice, with high accuracy rates. The research used acoustic features to analyze recordings from over 18,000 participants and identified significant vocal variations between individuals with and without the condition.
New research reveals that disrupted energy production in the kidneys contributes to progressive kidney disease in diabetes. Monitoring urinary lactate levels may help predict prognosis and guide management for diabetic kidney disease.
A new study identifies children at high risk of developing type 2 diabetes and strategies for prevention, including anti-obesity medication and lifestyle changes. Higher levels on certain diabetes screening tests and worsening obesity may better predict diabetes risk in children.
Researchers from the University of Virginia Health System have made significant discoveries about the genetic influences on fatty acid metabolism in diverse populations. The study found broad similarities among groups but also notable differences, highlighting the need for genetic studies in diverse groups.
A new American Heart Association advisory introduces the concept of cardiovascular-kidney-metabolic (CKM) syndrome, which affects nearly every major organ. The approach highlights the importance of screening for CKM-related conditions and addressing social factors to prevent progression.
Research reveals that low muscle mass is associated with a two-fold risk of death from cardiovascular disease in individuals with diabetes. The study found that body composition, not just weight loss, plays a crucial role in managing weight in people with diabetes.
A recent study demonstrated that lasting remission of type 2 diabetes is feasible in the real-world setting through a low-calorie diet and weight loss maintenance. The DiRECT trial showed significant weight loss and remission rates, even after five years, with participants who maintained their weight losing type 2 diabetes permanently.
Researchers analyzed UK data to identify patterns of illnesses in individuals leading up to a type 2 diabetes diagnosis. High blood pressure, respiratory tract infections, heart conditions, and asthma were commonly observed, suggesting earlier diagnosis may be possible.
Researchers found tirzepatide equally effective in treating young-onset and late-onset type 2 diabetes, improving HbA1c levels and weight. The drug also showed similar benefits in cardiometabolic markers such as waist circumference and blood pressure.
A new study has identified commonly prescribed antibiotic, antipsychotic and prokinetic drugs as being associated with a higher risk of sudden cardiac arrest (SCA) in individuals with type 2 diabetes. Low fasting blood sugar levels are also linked to SCA, a leading cause of death.
The Second International Consensus Report on Precision Diabetes Medicine addresses the need for personalized approaches in diabetes care. The report highlights the potential of precision medicine to improve prevention and treatment outcomes by accounting for disease heterogeneity.
A UK study found that emergency department screening for type 2 diabetes could identify tens of thousands of previously undiagnosed cases every year. The study used the glycated haemoglobin test to screen 1,388 patients, yielding an additional 9% of type 2 diabetes cases and 30% of prediabetes cases.
Diagnosed with type 2 diabetes at age 30 can lead to a reduced life expectancy of up to 14 years due to complications such as heart attack, stroke, and cancer. The analysis found that every decade of earlier diagnosis was associated with about four years of reduced life expectancy.
Studies show that people with metabolically healthy obesity (MHO) have a 50% increased risk of coronary heart disease, despite not exhibiting metabolic complications. This raises questions about the validity of the MHO concept.
In a randomized clinical trial, weekly tirzepatide showed greater reductions in HbA1c levels and body weight compared to prandial insulin as an additional treatment in people with inadequately controlled type 2 diabetes. The study also found less hypoglycemia with tirzepatide.
Nick Burton's research aims to identify bacteria that influence insulin production and signaling, with the goal of finding new therapeutic strategies for Type 2 diabetes. Preliminary results from a small-scale pilot study are promising, suggesting that certain bacteria may play a role in regulating insulin levels.