Articles tagged with Type 2 Diabetes
Research shows a significant decline in death rates after a first heart attack for individuals without diabetes and those with type 2 diabetes. However, this trend is absent in people with type 1 diabetes. The study suggests that improved standard care following a heart attack may contribute to the observed differences.
A large study found that people with an evening chronotype were more likely to engage in unhealthy lifestyle behaviors such as smoking, poor sleep, and physical inactivity. These individuals had a 72% higher risk of developing diabetes compared to those with a morning chronotype.
A study by Brigham and Women's Hospital found that evening 'chronotype,' going to bed late and waking up late, is associated with a higher risk of developing diabetes. Participants with later sleep and wake times had less healthy lifestyles and were at greater risk of developing diabetes than those with early-bird sleep habits.
A new genetic study revealed the link between type 2 diabetes, lung disorders, and the gastrointestinal tract. The research suggests that individual responses to GLP-1R agonist drugs depend on DNA variants in the target gene, and high blood sugar levels can directly cause lung complications.
A new study by Columbia University's Mailman School of Public Health reveals substantial racial and ethnic inequities in developing type 2 diabetes after gestational diabetes. The findings show a fourfold increased risk among Black individuals, with 18.5% incidence rate, compared to 5% in White individuals.
Research presented at the EASD Annual Meeting found that low-dose aspirin among older adults aged 65 and older is associated with a 15% lower risk of developing type 2 diabetes. The study also showed a slower rate of increase in fasting plasma glucose levels among those taking aspirin.
Researchers discovered a gut bacteria that helps reduce insulin resistance and protect against diabetes. The study found that a specific bacteria, Alistipes indistinctus, consumed excess monosaccharides in the gut, lowering blood sugar levels and reducing insulin resistance.
A new study found that people who received free produce prescriptions experienced increased fruit and vegetable consumption, leading to improved body mass index, blood sugar, and blood pressure levels. This research suggests that produce prescription programs may be an effective way to address food insecurity and promote health.
Researchers at UC Irvine issue a warning that GLP-1RA's may be dangerous for children due to the risk of nutrient imbalance and abuse. The team notes that children need energy and sufficient calories for growth and development, and any change in their diet and exercise balance can have long-term health consequences.
A new study from the University of Copenhagen reveals that GDF15 improves insulin sensitivity in rodents, particularly in their liver and fatty tissue. This finding raises interesting perspectives for treating type 2 diabetes and high blood pressure, as increased insulin sensitivity is a critical indicator of health.
Patients with type 2 diabetes are at a higher risk of developing cardiovascular disease, and the new guidelines recommend systematic screening, lifestyle changes, and medication to reduce this risk. The guidelines also emphasize the importance of managing heart failure, kidney damage, and atrial fibrillation in these patients.
A recent study published in Preventive Medicine found that erectile dysfunction is associated with a 34% increased risk of developing prediabetes or type 2 diabetes. Additionally, 75% of patients developed prediabetes or type 2 diabetes within a year of ED diagnosis.
Researchers found that urine levels of adenine are predictive and causative biomarkers of looming progressive kidney failure in patients with diabetes. An oral therapeutic drug showed promise in mice by reducing kidney adenine levels and protecting against diabetic kidney disease.
A recent study by Pennington Biomedical Research Center identifies GDF15 as a protein that acts as a cellular signal to enhance insulin secretion. High-intensity exercise training in patients with type 2 diabetes was found to have elevated levels of GDF15, associated with improved glycemic control.
A new study found that a simple blood test can predict the risk of progressive heart and kidney disease in people with Type 2 diabetes. The test measures levels of four biomarkers, which fell after treatment with canagliflozin, a type 2 diabetes medicine.
A new study reveals that being divorced is associated with a two-thirds higher risk of lower limb amputation (LLA) in individuals with diabetes compared to those who are married. Additionally, men have a 57% higher risk of LLA than women. The study also found that obesity has a less-than-half the risk of LLA for people with normal weight.
A new study in the American Journal of Preventive Medicine documents a consistent risk level across race and gender for victims of partner violence and child abuse. The risk is similar among adult males and females and lower income Black and White Americans, increasing by 20-35% compared to those without interpersonal violence.
Chronic disease medications impair the body's ability to regulate core temperature, increasing the risk of heat-related illness in elderly patients. Exercise and improved fitness levels can help mitigate these effects, but bodily impairments from chemotherapy and medications may limit exercise capacity.
Scientists have discovered a potential new treatment approach for non-alcoholic fatty liver disease by targeting a receptor called Adgrf1. Overexpressing Adgrf1 improved insulin sensitivity and reduced lipid accumulation in liver cells, suggesting its role in fat metabolism.
Researchers have identified four metabolism-related biomarkers linked to an increased risk of metastatic prostate cancer in Black men. These biomarkers could lead to improved testing and treatments for this high-risk population, who are more than twice as likely to die from the disease.
A recent study at UC Irvine found that semaglutide medication can lead to significant weight loss and reduce cardiovascular risk in 93 million U.S. adults. The medication may prevent up to 1.5 million heart attacks and strokes over 10 years, resulting in 43 million fewer obese people.
An intensive lifestyle intervention was associated with increased employment rates and improved labor market outcomes. The study suggests that such interventions can positively impact individuals with type 2 diabetes, highlighting the importance of considering labor market productivity in disease management.
A new study found that intensive lifestyle intervention, including weekly counseling on diet and exercise, is associated with increased employment among people with type 2 diabetes. Study participants without a college degree had even larger employment gains from lifestyle changes recommended by specialists.
A study found that longer duration of type 2 diabetes is associated with decreased brain structure and increased white matter hyperintensities. Despite this, cognition was not affected, highlighting the need for early screening for cognitive disorders in diabetic patients.
Researchers at West Virginia University are tracing the cause of diabetic heart disease using diabetic animal models to examine mitochondrial function. They hope to understand how faulty protein import affects the mitochondria and explore potential treatments to improve energy production and reduce cardiovascular risk.
A Hong Kong study of 1.5 million people found that young-onset type 2 diabetes is associated with higher rates of hospital stays for mental health disorders. The study suggests that addressing mental health needs may be crucial in reducing hospitalization rates for young adults with type 2 diabetes.
A study published in Stroke found significant disparities in stroke risk factors between Black and non-Black adults. However, after one year of intensive medical intervention, some risk factors were reduced in Black adults.
The American College of Physicians recommends starting colorectal cancer screening at age 50 for asymptomatic adults with average risk. The guideline aims to balance benefits and harms of screening in this population. Screening in younger adults may not offer significant net benefit due to lower incidence rates.
A world-first study from the University of South Australia exposes the real weight gains of everyday Australians, finding that weight fluctuates throughout the year. The study highlights the importance of targeting temporal hot spots to curb unhealthy weight fluctuations and prevent unwanted weight gain.
Researchers found a genetic link that explains how certain individuals store fat at the abdomen but remain protected from type 2 diabetes. This discovery could pave the way for personalized medicine, tailoring treatments to individual genetic variations.
A study by I.R.C.C.S. Neuromed found that high consumption of ultra-processed foods significantly increases mortality risk among people with type 2 diabetes. Even those following a Mediterranean diet are at increased risk if ultra-processed foods account for a large share of their diet.
A randomized controlled study found that participants who restricted their daily eating to between noon and 8 p.m. lost more weight and showed similar improvements in blood sugar levels compared to those on a calorie-restricted diet.
A program integrated community health workers into patient outreach to improve health, doubling annual visits to older adults with type 2 diabetes and dementia. The program resulted in a 17% reduction in hospital admissions and an 11% decline in emergency room visits among homebound patients.
A new study found that snacking on high-quality foods can improve blood fat and insulin responses, while late-night snacking may have unfavorable effects. The researchers analyzed data from over 1,000 people in the UK and found no association between snack frequency or calories consumed and health measures.
A combination of Lactobacillus acidophilus and Lacticaseibacillus rhamnosus strains successfully inhibited the production of superantigens causing toxic shock syndrome. Probiotics may also prevent growth of Staphylococcus aureus, a virulent strain that produces proteins triggering the disease.
A study of over 100,000 participants found that eating breakfast late may increase the risk of developing type 2 diabetes. The research suggests that a first meal before 8 am and an early dinner may help reduce this risk.
A comprehensive review of biochemical markers for bone fragility in diabetes identifies low bone turnover and alterations in bone quality as key factors. The study suggests that glycemic control, AGEs, and serum IGF-1 may have predictive value for fracture risk in patients with diabetes.
A team of researchers has discovered a plant molecule that acts in the brain and improves blood sugar regulation. The dahlia extract was shown to considerably improve blood sugar regulation in preclinical trials and clinical studies, offering new hope for people with prediabetes or type 2 diabetes.
Researchers at UC Berkeley discovered that deep-sleep brain waves can regulate the body's sensitivity to insulin, improving blood sugar control. The study found that synchronized brain waves during deep sleep predict next-day glucose control, even after controlling for other factors.
Researchers found that aerobic exercise combined with weightlifting, afternoon exercise, and post-meal exercise can provide better glucose control; no weight loss required to see benefits. More movement is generally better for insulin sensitivity.
A large study published in the Journal of Clinical Endocrinology & Metabolism has found that moderate to light alcohol consumption does not protect against obesity and type 2 diabetes. The research, which analyzed data from over 408,000 participants, confirmed that heavy drinking increases measures of obesity and risk of type 2 diabetes.
A 12-year study by Pennington Biomedical researchers found that metabolic surgery provides better results, less regression, compared to medical or lifestyle intervention for patients with class 1 obesity. The study showed significant improvements in glycemic control and weight loss, with high rates of diabetes remission.
A new study found that higher doses of oral semaglutide improved regulation of blood sugar levels and weight loss compared to lower doses. Participants who received the 25mg and 50mg doses lost an average of 17.5 pounds, nearly twice as much weight loss as those who took the lowest dose.
Once-weekly Icodec demonstrated superior HbA1c reduction compared to once-daily Degludec after 26 weeks, but no difference was found in weight change. However, Icodec showed a higher rate of combined level two or three hypoglycemic events
The global prevalence of diabetes is expected to more than double from 6.1% to 12.8% by 2050, with every country experiencing an increase. The study found that high body mass index and dietary risks are primary contributors to type 2 diabetes.
The global diabetes crisis is accelerating due to widening inequity, with structural racism and geographic disparities exacerbating the problem. The new Series projects that over 1.3 billion people will live with diabetes by 2050, with marginalized communities facing reduced access to care and worse health outcomes.
A recent review article highlights how metformin increases miRNA let-7 levels in the liver, reducing hepatic glucose production. Additionally, it activates glucose conversion to lactate and acetate in the intestine, establishing a crosstalk between gut and liver that contributes to its antidiabetic effects.
A study found that people with a history of gestational diabetes are more likely to develop type 2 diabetes within nine years after delivery, particularly in Black and Hispanic women. Regular diabetes screenings in the early postpartum period can alter disease progression and improve control.
A case series study demonstrated that a whole-food, plant-predominant dietary pattern and standard medical treatment can successfully achieve type 2 diabetes remission in 37 percent of patients. The study contributes novel information on the feasibility of achieving remission simply by eating healthy food.
Researchers have found a hidden mechanism connecting cancer and diabetes, where cancer cells don't respond well to insulin, leading to faster cancer growth. Insulin resistance can also cause muscle loss and strength decline in cancer patients.
A review of studies found that reducing meal frequency and cutting out late-night snacks can improve insulin resistance, brain health, and glycemic control. This approach may also help regulate appetite hormones and reduce calorie intake, ultimately staving off obesity and metabolic disorders.
A new study suggests that eating more calories earlier in the day may improve metabolic health by reducing blood sugar fluctuations and inflammation. The study found that participants who followed an early time-restricted feeding pattern experienced a decrease in time above normal blood glucose levels, thereby improving metabolic health.
Researchers have identified a number of candidate genes that may drive the development of conditions like Type 2 Diabetes. The study found that proteins such as PCSK1, SUR1 and GLUT2 play a role in calcium ion dynamics and insulin secretion.
Recent studies show that continuous glucose monitoring (CGM) is effective in improving glycemic control, reducing hypoglycemia risk, and increasing access to diabetes technologies. The technology has the potential to replace self-monitoring of blood glucose for insulin-requiring patients and become a standard for managing Type 2 Diabetes.
Researchers identified 10 genomic regions associated with insulin resistance after a meal, including a gene that affects glucose transport into cells. The study suggests targeted interventions may be possible in preventing type 2 diabetes.
Studies found that low birthweight is independently linked to an increased risk of type 2 diabetes, with younger age at diagnosis and fewer comorbidities. Lower birthweight was also associated with a higher use of diabetes drugs and more severe hypertension.
The new scientific statement highlights the importance of identifying the root cause of pediatric cardiomyopathy to develop effective treatment strategies. Genetic testing is recommended for all children with cardiomyopathy, which may lead to financial and emotional cost savings.
A new randomized controlled trial found that taking metformin after testing positive for SARS-CoV-2 reduces the risk of developing long COVID by 40%. The study, published in The Lancet Infectious Diseases, involved over 1,100 patients and showed metformin prevented over 40% of cases of long COVID over a 10-month follow-up period.
A new study published in Nature Genetics sheds light on how humans maintain healthy blood sugar levels after meals and how the process goes wrong in type 2 diabetes. The findings could help inform future treatments of the condition, which affects over 460 million people worldwide.
A study of over 55,000 people identified new genetic variants associated with insulin resistance after eating, which may help inform future treatments of type 2 diabetes. The discovery highlights the importance of understanding how glucose regulation works in the body, particularly in the fed state.