A new evolutionary theory proposes that asexual parasites can temporarily infect a wider range of hosts as harmful genetic mutations build up. This process, known as Ratchet-Driven Generalism, may make the parasite less specialized and more adaptable. However, it may also ultimately reduce fitness and increase extinction risk.
SourceUniversity of East Anglia·JournalTrends in Parasitology·DateJul 1, 2026
Researchers at Washington University School of Medicine engineered a hookworm to produce and deliver an antibody neutralizing tetrodotoxin. The parasites successfully produced the antitoxin and secreted it into the bloodstream, demonstrating a potential platform for long-term drug delivery.
SourceWashington University in St. Louis·JournalNature Communications·TypeExperimental study·DateJun 3, 2026
A disease-causing tapeworm has been detected in Washington coyotes, which can spread to domestic dogs and humans if ingested through contaminated food or feces. The parasite's life cycle involves multiple hosts, including rodents and other canid species, making it a public health threat.
SourceUniversity of Washington·JournalPLOS Neglected Tropical Diseases·TypeExperimental study·DateApr 6, 2026
Researchers at Adelaide University have discovered a new gut–brain signalling pathway that governs how parasitic infections lead to nausea, appetite loss and other sickness symptoms. The study shows two specialised gut cell types work together to sense parasites and activate protective responses through the vagus nerve.
SourceAdelaide University·JournalNature·TypeExperimental study·DateMar 25, 2026
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A new study found that Roman soldiers at Vindolanda fort near Hadrian's Wall were infected with intestinal parasites, including roundworms, whipworms, and Giardia duodenalis. This suggests inadequate sanitation and hygiene practices, potentially leading to malnutrition and chronic infections.
SourceUniversity of Cambridge·JournalParasitology·DateDec 18, 2025
A study published in PLOS Neglected Tropical Diseases has shown that combining country-level information with individual-level variables can improve the identification of soil-transmitted helminth infections among migrant populations. Researchers found that country-level indicators are stronger predictors than individual-level variable...
SourceLancaster University·JournalPLOS Neglected Tropical Diseases·TypeData/statistical analysis·DateJul 31, 2025
Researchers discovered a new pathway to boost immunity against parasitic infections, suggesting that NSAIDs like ibuprofen could be repurposed as anti-parasitic treatments. Gasdermin C plays a crucial role in this process, targeting and penetrating Rab7-positive vesicles to reduce prostaglandin d2 levels.
SourceUniversity of Pittsburgh·JournalImmunity·DateJul 22, 2025
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A 500-year-old latrine from Bruges, Belgium has yielded evidence of intestinal parasites, shedding light on the spread of diseases through medieval travel and trade. The discovery provides key insights into human migration and disease transmission in the past.
SourceMcMaster University·JournalParasitology·DateDec 6, 2024
Researchers discovered a parasite protein that enhances wound healing in mice by stimulating immune cells to promote tissue regeneration and inhibit scarring. The protein, TGM, accelerates wound closure and improves skin regeneration.
SourceRockefeller University Press·JournalLife Science Alliance·TypeExperimental study·DateAug 23, 2024
A study analyzing canned salmon from 1979 to 2021 found stable anisakid worm levels in coho and sockeye salmon, while pink and chum salmon showed a rise. This suggests that the marine food web has adapted to changing conditions, with rising parasite levels indicating potential ecosystem shifts.
SourceUniversity of Washington·JournalEcology and Evolution·TypeExperimental study·DateApr 4, 2024
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A potentially fatal parasite has been discovered in the Colorado River in California, affecting dogs and causing liver and intestinal illness. Researchers confirm the presence of Heterobilharzia americana, a flatworm that can be transmitted through snails and water, highlighting the need for awareness and precautions among dog owners.
SourceUniversity of California - Riverside·JournalPathogens·DateMar 14, 2024
Researchers uncovered traces of Giardia duodenalis, a common cause of debilitating diarrhoea, in two Jerusalem latrines dating back to the biblical Kingdom of Judah. The study suggests dysentery was endemic in the Kingdom of Judah.
SourceUniversity of Cambridge·JournalParasitology·DateMay 25, 2023
Researchers found no association between social behavior and parasite infection in Asian elephants, despite studying three key aspects of their social life. The study suggests that social benefits may outweigh the costs of sociality for these animals.
SourceUniversity of Turku·JournalBehavioral Ecology and Sociobiology·DateJun 28, 2022
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A new analysis of ancient faeces found at Durrington Walls has uncovered evidence of parasitic worms, suggesting the inhabitants feasted on cattle and fed leftovers to their dogs. The findings indicate that people ate raw or undercooked internal organs from infected animals, resulting in parasite eggs passing through the body.
SourceUniversity of Cambridge·JournalParasitology·TypeImaging analysis·DateMay 19, 2022
Scientists tracked Cryptosporidium in real-time, revealing a simplified lifecycle that completes in three days with only three stages: asexual cells, male cells, and female cells. This understanding paves the way for potential vaccines or therapies to combat the disease.
SourceUniversity of Pennsylvania·JournalPLOS Biology·TypeObservational study·DateApr 19, 2022
Researchers analyzed a ceramic pot from Sicily and found eggs of whipworm parasites, confirming it was used as a chamber pot. The technique provides a crucial tool for identifying ancient pots with special purposes.
SourceUniversity of Cambridge·JournalJournal of Archaeological Science Reports·TypeObservational study·DateFeb 10, 2022
A breakthrough oral vaccine candidate has been developed to prevent hookworm infection, which affects half a billion people worldwide. The vaccine triggers a strong immune response and reduces worm numbers by up to 94% in mice trials.
SourceUniversity of Queensland·JournalVaccines·DateOct 26, 2021
A team of researchers has discovered intestinal parasite infection in ancient faeces from the Çatalhöyük village, dating back to 7,100 BC. Whipworm eggs were found in two coprolites, providing early evidence of human disease in the Near East.
SourceUniversity of Cambridge·JournalAntiquity·DateMay 31, 2019
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Research published in Applied and Environmental Microbiology found that probiotics increased the severity of cryptosporidiosis in mice, defying initial hypotheses. The study suggests that manipulating gut microbiota may hold potential for developing probiotics to mitigate the disease.
SourceAmerican Society for Microbiology·JournalApplied and Environmental Microbiology·DateAug 31, 2018
The study found that intestinal parasites like whipworm and roundworm did not decrease in prevalence during the Roman Period, but instead increased. The Roman public baths may have actually helped spread these parasites due to infrequent water changes and scum buildup.
SourceUniversity of Cambridge·JournalParasitology·DateJan 7, 2016
A new review argues that most intestinal parasite infections have no negative impact in well-nourished people with low overall parasite loads. In some cases, parasite infections could activate the immune system and prevent disorders caused by inflammation of the intestines.
Researchers discovered fossilized tapeworm eggs in 270-million-year-old shark feces, indicating that intestinal parasites in vertebrates are much older than previously known. The finding provides a new timeline for the evolution of present-day parasitic tapeworms.
Research shows B cells produce critical regulatory chemicals called cytokines and amplify T cell dependent immune responses to protect against intestinal parasite Heligmosomoides polygyrus. B cells also promote the production and long-term maintenance of essential T helper 2 cells, which are crucial for protection from this pathogen.
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