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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

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Vitamin C stresses and kills mutant cancer cells

A new study published in Science magazine reveals that vitamin C can selectively kill colorectal cancer cells with certain mutations, such as KRAS and BRAF. The research found that these mutated cells take up oxidized vitamin C through a specific receptor, leading to oxidative stress that inactivates an enzyme required for growth.

How vitamin C helps plants beat the sun

Researchers from RIKEN and Okayama University identified PHT4;4 as the transport protein allowing vitamin C to enter chloroplasts. This discovery could lead to crop plants with higher tolerances to environmental stress, reducing damage to farmland in regions with strong light.

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Two sensors in one

New nanoparticles can perform magnetic resonance imaging (MRI) and fluorescent imaging simultaneously, allowing for the tracking of specific molecules produced in the body. The particles were demonstrated to detect vitamin C in mice, showing strong fluorescent signals where vitamin C is present but little MRI contrast.

Wild tomato species focus of antioxidant study

Scientists have discovered that wild tomato species like Solanum habrochaites and Solanum peruvianum contain higher levels of antioxidants, which can help improve the health-related characteristics of cultivated tomatoes. The study provides valuable insights for breeding programs aiming to enhance antioxidant traits in elite tomato lines.

Coating stents with vitamin C could reduce clotting risks

Researchers have found that coating stents with vitamin C could lower implant-related risks by inhibiting smooth muscle cell growth and encouraging endothelial cells. This technique could make stents safer for millions of Americans who receive them annually.

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Can citrus ward off your risk of stroke?

A study of 65 participants with intracerebral hemorrhagic stroke and 65 healthy individuals found that those with depleted vitamin C levels had a higher risk of stroke. The study suggests that maintaining normal vitamin C levels may help reduce stroke risk.

Vitamin C and E supplements hampers endurance training

A new study suggests that high doses of vitamin C and E supplements can blunt the improvement of muscular endurance through cellular adaptions. The study found that markers for muscle mitochondria production increased only in the group without supplements.

Vitamin C helps control gene activity in stem cells

Researchers at UCSF discovered that vitamin C helps release brakes on genes in mouse stem cells, potentially playing a key role in normal development. This finding may lead to the use of vitamin C in IVF and cancer treatments, as it can stimulate gene activity similar to early embryonic development.

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Study finds vitamin C can kill drug-resistant TB

Researchers at Albert Einstein College of Medicine discovered that vitamin C can kill drug-resistant tuberculosis (TB) bacteria in laboratory culture, suggesting a new approach to shorten TB therapy. The study found that vitamin C induced a Fenton reaction, causing reactive oxygen species that kill the TB bacteria.

Vitamin C does not lower uric acid levels in gout patients

New research published in Arthritis & Rheumatism found that vitamin C supplementation had a weak effect on lowering uric acid levels in gout patients. The study suggests that vitamin C may not be a viable therapy for reducing uric acid levels in patients with established gout.

Vitamin C supplements linked to kidney stones

A large population-based study of men found that those taking vitamin C supplements are twice as likely to develop kidney stones as non-supplement users. The risk increased with the frequency of supplement use. Conversely, multivitamin use was not associated with an increased risk of kidney stones.

Eating bright-colored fruits and vegetables may prevent or delay ALS

A study published in Annals of Neurology found that diets high in carotenoids, particularly beta-carotene and lutein, were linked to reduced risk of amyotrophic lateral sclerosis (ALS). The researchers also discovered that individuals with higher intake of antioxidants had a lower ALS risk.

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Fetus suffers when mother lacks vitamin C

A new study at the University of Copenhagen found that maternal vitamin C deficiency during pregnancy can stunt fetal hippocampus development by up to 10-15%, potentially leading to memory problems and learning difficulties. The damage cannot be reversed even with vitamin C supplements after birth.

Nutrition tied to improved sperm DNA quality in older men

A study by Berkeley Lab scientists found that older men who consume more vitamin C, E, folate, and zinc have less sperm DNA damage. This suggests that adequate micronutrient intake can help counteract the detrimental effects of aging on sperm genome health.

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Vitamin C improves pulmonary function in newborns of pregnant smoking women

A new study has found that vitamin C supplementation in pregnant women who are unable to quit smoking significantly improves pulmonary function in their newborns. Daily use of vitamin C (500 mg/day) improved peak tidal expiratory flow and respiratory compliance, returning them nearly to the levels seen in non-smokers.

Big doses of vitamin C may lower blood pressure

A review of 29 clinical trials found that taking an average of 500 milligrams of vitamin C daily reduced blood pressure by 3.84 millimeters of mercury in the short term. However, more research is needed to understand its implications as a treatment for high blood pressure.

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Low vitamin C levels may raise heart failure patients' risk

Research found that heart failure patients with low vitamin C intake had shorter intervals without major cardiac issues or death and were more likely to die from cardiovascular disease. Inflammation pathways in heart failure may contribute to poor health outcomes.

Additives meant to protect vitamin C actually cause more harm

Researchers found that anti-caking agents in powdered vitamin C products can accelerate degradation, even protecting it from moisture. This is due to the chemical properties of these agents, which can absorb or repel water and lead to further reactions that lower the nutrient's stability.

Could an apple a day keep sepsis away?

Researchers aim to determine optimal Vitamin C dosing schedule and test therapy in septic patients to moderate organ dysfunction and improve outcomes. A potential new treatment for sepsis may be on the horizon thanks to a significant grant.

Vitamin C may be beneficial for asthmatic children

A study by Al-Biltagi and Hemila found that vitamin C supplementation increased FEV1 levels by 37% in younger children with no mold exposure, while the benefit was smaller in older children. Vitamin C showed greatest benefit in mild asthma symptoms.

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Gazpacho ingredients lose vitamin C during preparation

A new study reveals that gazpacho's vitamin C content and other organic acids decrease significantly after preparation. Peppers and tomatoes have higher levels of these nutrients, while cucumbers contain the lowest amount. The authors suggest consuming gazpacho immediately or preserving it correctly to maintain its antioxidant properties.

Could chocolate and oranges help prevent frailty in old age?

Researchers at the University of Nottingham are exploring whether chocolate and orange consumption can slow down muscle loss and frailty in older adults. The study aims to investigate the impact of cocoa and vitamin C on blood flow to leg muscles, with potential implications for improving mobility and reducing fall-related deaths.

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See off Alzheimer's with the color purple

A groundbreaking study by Professor Douglas Kell found that poorly-bound iron causes the production of hydroxyl radicals, leading to degenerative diseases. Purple fruits and green tea are identified as excellent sources of iron chelators, which can bind iron tightly.

Vitamin C: A potential life-saving treatment for sepsis

Researchers have found that vitamin C can prevent the onset of sepsis and even reverse the disease by restoring blood flow to vital organs. Early and delayed injections of vitamin C have been shown to improve survival rates in mice with sepsis, making it a promising treatment option.

Vitamins E and C appear to have little effect on age-related cataract

A study of over 11,500 male physicians found that long-term use of vitamins E and C had no significant impact on the development or extraction of age-related cataracts. The researchers concluded that high-dose supplementation with these vitamins has little effect on rates of cataract diagnosis and extraction.

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Supermarket lighting enhances nutrient level of fresh spinach

Fresh spinach leaves stored under continuous light exposure show significantly higher levels of vitamins C, K, E, and folate, as well as healthful carotenoids lutein and zeaxanthin. Continuous light exposure after nine days increases folate levels by up to 100% and vitamin K levels by 50-100%

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Vitamins stored in bathrooms, kitchens may become less effective

A Purdue University study reveals that high humidity in bathrooms and kitchens can cause vitamins and health supplements to lose their potency. Storing products in dry conditions, below their deliquescence relative humidities, can help maintain their effectiveness.

JCI online early table of contents: March 1, 2010

Researchers at the NIH have identified a key role for the protein Slc23a1 in controlling vitamin C levels in mice, which is essential for perinatal survival. Additionally, they discovered that treating multidrug-resistant leukemia cells with a specific drug can resensitize them to glucocorticoids and other cytotoxic agents by activatin...

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Fruit juices contain more vitamin C than their labels indicate

Researchers at the University of Santiago de Compostela have developed a new technique to accurately measure vitamin C in fruit juices and soft drinks. The study found that only two out of 17 samples matched their labels, revealing higher levels of natural vitamin C in other drinks.

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GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Study reveals new role of vitamin C in skin protection

A new study reveals that vitamin C helps promote wound healing and protects skin cells from DNA damage, a finding with great relevance to the cosmetics industry. The research also suggests that vitamin C can help remove DNA damage caused by free radicals, leading to potential advances in skin regeneration and cancer prevention.

Vitamin C deficiency impairs early brain development

Research at University of Copenhagen suggests that vitamin C deficiency in pregnant and breast-feeding women may lead to impaired mental development in new-born babies. Guinea pigs subjected to moderate vitamin C deficiency have reduced hippocampal neurons and spatial memory impairments.

Stopping diabetes damage with vitamin C

Researchers found that a combination of insulin and vitamin C stopped blood vessel damage caused by Type 1 diabetes in patients with poor glucose control. The therapy's effectiveness was proven in humans for the first time, offering hope for diabetic patients to avoid complications.

Support for adjunctive vitamin C treatment in cancer

A recent study on vitamin C treatment in cancer has been disputed by a nutrition expert due to the use of oxidized form of vitamin C and toxic doses. Contrasting findings suggest that high-dose vitamin C may have beneficial effects on cancer cells, tumor cell death, and postsurgical healing.

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CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Many middle-aged and older Americans not getting adequate nutrition

A new study published in the Journal of the American Dietetic Association found that many middle-aged and older Americans are not getting adequate nutrition. Supplement use was associated with meeting recommended dietary intakes for calcium, magnesium, and vitamin C, but potassium intake remained low regardless of supplement use.

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Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.