Articles tagged with Immunoassays
Researchers developed an antibody test for Mpox that accurately identifies those with infection and vaccine-derived antibodies, helping authorities prioritize vaccine use and study disease transmission. The test, validated in Rwanda, uses only four key antibody signatures to ensure affordability and accessibility.
Researchers propose a new conceptual framework for neutrophils, highlighting their dynamic and adaptable nature. The study reveals neutrophils' functional diversification and immunological memory capabilities, opening avenues for innovative therapeutic strategies.
Yale researchers have developed a novel diagnostic method for detecting leptospiral virulence-modifying proteins in blood and urine, which could lead to early diagnosis and improved treatment options. The test has the potential to transform leptospirosis management globally by enabling timely treatments and mitigating disease severity.
The new serum amyloid A (SAA) assay demonstrated high reproducibility and broad linear measurement range, suitable for low-grade to high-level inflammatory states. Its strong agreement with established methods supports its adoption in routine diagnostics.
Researchers developed a novel, homogeneous customizable OpenGUS immunoassay that detects target analytes quickly and effectively. The platform provides a hassle-free approach for biomarker detection in point-of-care diagnostics, high-throughput testing, and environmental monitoring.
Researchers from Osaka Metropolitan University have developed a method to detect coronavirus spike proteins quickly and selectively using a light-induced immunoassay. The technique uses a milliwatt-level laser and can complete the entire process in under 5 minutes.
Researchers from Tokyo Metropolitan University have engineered a micro total analysis system that quantifies target chemicals in a microfluidic chip without pumps or expensive detectors. The device uses gas production to drive ink flow and measure the original chemical concentration.
Researchers at Gwangju Institute of Science and Technology developed metal-enhanced fluorescence probes for rapid and accurate detection of influenza viruses. The probes showed high sensitivity and specificity, detecting the virus even at low concentrations, with a remarkable accuracy of over 99%.
Scientists have developed a new method to deliver genetic information to stem cells using nanoparticles coated with a specific polymer, enabling more efficient control over cellular differentiation. This innovation has the potential to improve the efficiency and effectiveness of regenerative medicine treatments.
A research team led by Dr Chen Ting-Hsuan developed a new rapid antibody test that shows the level of antibodies readable by the naked eye, displaying results as a length of a visual bar like a mercury thermometer.
Researchers at Gwangju Institute of Science and Technology (GIST) have developed a new technique to easily visualize viruses using an optical microscope, called the Gires-Tournois immunoassay platform. The platform uses 'slow light' technology to detect coronavirus particles by slowing down light that gets reflected around them.
Biologists isolated the SARS-CoV-2 nucleoprotein in its pure form to create more accurate antibody tests. The new approach significantly improves sensitivity, increasing the ability to detect antibodies to the nucleoprotein. This breakthrough helps determine if vaccinated individuals have been infected with COVID-19.
Researchers developed a novel immunosensor called BRET Q-body, which works on the bioluminescence resonance energy transfer principle. The sensor detects antigens by inducing fluorescence through an enzyme-luminescent substrate reaction, allowing for simple and accurate immunoassay tests.
Developed by Chinese scientists, this lateral flow immunoassay can detect SARS-CoV-2 RNA in under an hour with a limit of detection of 500 copies/mL. The test kit has been commercialized and received regulatory approval for its use as an on-site diagnostic tool.
Two plasma and 10 cerebrospinal fluid biomarkers were identified to aid in early detection of MS with high sensitivity and specificity. These biomarkers may help monitor treatment response and disease progression.
Researchers found that therapeutic plasma exchange can rapidly reduce HIT antibody levels, making patients eligible for urgent cardiac surgery sooner. The study suggests using both functional and immunoassays to determine patient readiness, with the functional assay indicating lower antibody levels more quickly.
Patients with a history of heparin-induced thrombocytopenia (HIT) may be ready for urgent heart surgery sooner than previously thought, according to new research. A combination of appropriate blood screenings and therapeutic plasma exchange can help lower HIT antibody levels quickly.
Researchers at Princeton University have developed a new nanotechnology that amplifies fluorescent signals in biological tests, allowing for the detection of biomarkers at lower concentrations. This breakthrough could lead to improved early detection of diseases like cancer and Alzheimer's, enabling more effective treatment.
Yun-Hwa Peggy Hsieh is developing two new immunoassays to detect fish allergens and pork fat in raw and processed food products. The tests aim to protect consumers with allergies or dietary restrictions, particularly Muslims and Jews who avoid pork consumption.
Researchers at Georgetown University Medical Center developed a fast and accurate test to measure thyroid hormones, which may help diagnose and treat conditions like hypothyroidism and hyperthyroidism. The new test uses tandem mass spectrometry and is more specific than the current immunoassay test.
Researchers have developed a new test, called conformation-dependent immunoassay (CDI), that can detect prion proteins with 100% accuracy at smaller levels than conventional tests. The CDI test can also be used to identify infected animals before they show symptoms, potentially ending the practice of slaughtering entire herds.
Scientists at Rice University have created a new test that can detect glycoprotein immunoglobulin G in whole blood with high sensitivity and speed. The innovation uses gold nanoshells to overcome challenges in existing immunoassays, enabling doctors to make quicker diagnoses without the need for time-consuming sample preparation.
A novel immunoassay for FLC molecules has been developed and assessed for its sensitivity, latex-enhancement, and turbidimetric techniques. The new assay improves upon existing clinical laboratory tests for FLCs in identifying and monitoring patients with multiple myeloma and other diseases.