A study found that nursing home residents who wander, exhibit verbally abusive behavior, or have cognitive impairment are more likely to provoke injuries in others. Male residents and those living in Alzheimer's units were also at higher risk. The authors suggest focusing on the behavior of injured persons to prevent incidents.
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Researchers developed a novel metal-protein attenuating compound (MPAC) to target beta-amyloid interactions and slow cognitive decline. The pilot phase 2 clinical trial found that plasma beta-amyloid levels declined in patients taking the compound, while those on placebo levels increased.
A Stanford study found that 18% of Europeans with depressive disorder also had a breathing-related sleep disorder, which can increase the risk of feeling sleepy and irritable. The study suggests that treating sleep apnea may help control depression in patients.
Researchers found lasting cognitive deficits in individuals who started smoking marijuana before age 17. Those who began using marijuana at a younger age performed significantly worse on tests assessing verbal functions compared to those who started later or used it sparingly.
A new study suggests that nearly 90 percent of healthy diabetes patients have experienced brain volume loss, potentially contributing to cognitive decline. The research, led by Drs. Jitendra Sharma and Richard Chan, used MRI scans to compare brain health in diabetic and non-diabetic individuals within the same age cohort.
A study by Duke University Medical Center researchers found that older patients undergoing coronary artery bypass surgery are more likely to suffer cognitive decline due to lowered immunity to gram-negative bacteria. Cognitive decline was particularly pronounced in patients over 60, suggesting that boosting immunity may improve outcomes.
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A study of younger and older children with phenylketonuria (PKU) reveals significantly poorer adherence to recommended dietary controls in older children, affecting blood phenylalanine levels. Biochemical control can be challenging even in young patients, emphasizing the need for improved treatment options.
Researchers found that when treatment outcomes were impaired quality of life, such as severe functional or cognitive impairment, a significant number of patients (74.4% and 88.8%) lost their willingness to receive treatment. In contrast, the impact on preferences was more nuanced with mortality, where only when the likelihood increased...
A six-year study of people aged 40-70 found that those with diabetes and high blood pressure experience greater cognitive decline compared to their healthy counterparts. The study suggests controlling hypertension and diabetes before age 60 may help preserve mental abilities later in life.
A 52-week study found that patients treated with 6-12 mg of rivastigmine daily showed significantly better cognitive function than those on placebo or lower doses. The treatment reduced cognitive decline and improved outcomes in patients with mild to moderate Alzheimer's disease.
A study examining the link between fathers' alcoholism and male, elementary-school-aged children's intellectual, cognitive, and academic performance reveals children of antisocial alcoholics display lower intellectual performance, poorest academic achievement, and poorer abstract planning and attention abilities. Parental cognitive abi...
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Researchers found that estrogen use reduced cognitive decline in women with e2 and e3 ApoE alleles, but not in those with e4 variants. Estrogen also showed protective effects on carotid wall thickening and atherosclerosis.
A new study will investigate whether cognitive therapy can prevent relapses and recurrences of major depression as effectively as standard antidepressant medication. The study, funded by a $1.6 million NIMH grant, aims to help patients who suffer from recurring episodes of major depression.
Researchers have developed a new way to monitor brain damage in stroke patients, which could increase the number of eligible patients for clot-breaking treatments. The test combines cognitive assessments with MRI scans to identify patients with salvageable brain tissue.