Articles tagged with Memory Disorders
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Researchers identified three stages of memory processing: creating memories (6 hours), stabilizing them during sleep, and recalling and refining them. These findings have implications for the treatment of neurological disorders like PTSD.
Paxil has been shown to improve memory and brain structure in PTSD sufferers, with clinically significant improvements in memory and concentration observed. The study found increased hippocampal volume and decreased cortisol levels, leading to relief of PTSD symptoms.
A team of researchers used a computer game to study human navigation, identifying distinct brain cells responsible for spatial mapping (place cells) and goal-directed behavior (goal cells). The study demonstrates that humans use both visual and cognitive processes to navigate their environment.
A study published in Pharmacology, Biochemistry and Behaviour found that sage oil improved word recall test performance in healthy young adults. Sage is being investigated as a potential treatment for Alzheimer's Disease due to its ability to inhibit the enzyme acetylcholinesterase.
Researchers have found small, soluble aggregated proteins called ADDLs in the brains of individuals with Alzheimer's disease, up to 70 times more than in normal individuals. These proteins may be reversibly blocking memory function, providing a potential target for new therapeutic drugs.
Research suggests that schizophrenia impairs habitual prospective memory, leading to high rates of non-adherence to medication. The study found that people with schizophrenia are more likely to forget to turn over a counter during an obstacle course test.
Research from Washington University in St. Louis found that frontal lobe function can impact false memories in older adults. Contrary to common assumption, age-related cognitive decline may be linked to declines in executive control functions rather than memory skills themselves.
Max Planck researchers found that reducing SK3 channel production in the hippocampus of aged mice prevented learning and memory deficits. The study provides new insight into the mechanisms of age-related cognitive decline and suggests a potential therapeutic approach.
Researchers found that sleep deprivation zero to five hours after learning impaired spatial orientation and recognition of physical surroundings, but not recollection of specific facts or events. The findings suggest that sleep helps regulate neuronal function in the hippocampus during memory consolidation.
Research reveals that amyloid accumulation selectively reduces expression of genes essential for forming new memories, leading to early memory loss in Alzheimer's disease. The study suggests a new approach to treating the disease by blocking the effect of remaining amyloid on normal learning and memory.
Researchers Mark Gluck, Catherine Myers, and Martijn Meeter propose a novel interpretation of how the brain organizes sensory input into memories. They suggest that the entorhinal cortex handles incremental learning, while the hippocampus stores episodic memory.
A federal task force study has found that there is insufficient data to support the practice of routine dementia screening in primary care settings. The study suggests that the potential benefits of early diagnosis may outweigh the risks, but more research is needed to confirm this.
Researchers argue that age differences in memory studies are influenced by stereotype threat and social contexts. Older adults perform similarly to younger adults when making objective decisions and judging character.
Researchers at Northwestern University find brain tangles in normal aging and mild cognitive impairment, correlating with memory loss. Neurofibrillary tangles are more numerous in brain regions associated with memory function, suggesting a link between tangle density and memory performance.
A study found that heavy drinkers with fragmentary blackouts misremember drinking experiences while expecting positive outcomes. This phenomenon can contribute to problem drinking by reinforcing distorted beliefs about alcohol's effects.
Researchers at USF and VA hospitals found that rats with intrusive emotional memories can't remember new information. They also exhibited behavioral symptoms similar to those in people with PTSD after being reminded of the traumatic experience.
Researchers at Cold Spring Harbor Laboratory identified 92 unique fruit fly memory genes that could be important for understanding human learning and memory. The study found that many of these genes have counterparts in humans and may be potential targets for developing therapies to treat Alzheimer's disease.
A study published in the Journal of Neuroscience found that Alzheimer's patients who scored well on memory tests show distinct compensatory brain activity. This activity was observed in the right frontal and temporoparietal areas, and was associated with improved performance on semantic and episodic memory tasks.
A study published in the Proceedings of the National Academy of Sciences found an association between impaired glucose regulation and reduced hippocampal volume, leading to poorer memory performance. This suggests that improving glucose tolerance may have significant treatment implications for age-related cognitive decline.
A study found that clinicians' personal theories significantly impact diagnoses of mental disorders, with central symptoms leading to more accurate diagnoses. The researchers suggest that expert theorizing can be idiosyncratic and lead to conflicting diagnoses due to a lack of understanding of the underlying causes of mental disorders.
Researchers found that stimulating the prefrontal cortex in rats reduces fear responses by mimicking the brain's safety signal. The study suggests a new approach to treating anxiety disorders by using transcranial magnetic stimulation to control fear.
Researchers have discovered a new structure in the human brain linked to learning and memory, called the marginal division (MrD). This pan-shaped structure, composed of spindle-shaped neurons, plays a key role in linking other memory-related structures.
Researchers have developed a new diagnostic tool using PET scans to detect Alzheimer's disease more accurately. By analyzing brain activity, the scans can identify changes that occur before patients themselves may recognize problems.
Researchers found three distinct clusters of patients with different memory and brain profile patterns, suggesting multiple disease mechanisms. The 'cortical' subtype showed temporal lobe pathology, while the 'subcortical' subtype featured frontal-striatal region issues.
A controlled study found that memory training improved recalling people's names among participants with mild to minimal Alzheimer's Disease. Those who were more aware of their failing memories showed the most improvement.
Researchers found that 43% of participants with mild cognitive impairment had psychiatric symptoms, and 75% of those with dementia did. The study highlights the importance of recognizing and treating these symptoms to improve patient outcomes.
Researchers found that linoleic acid significantly improved vasodilatory responses and decreased systolic blood pressures in spontaneously hypertensive rats. The study also showed that linoleic acid administration improved spatial reference memory in older SHRs, suggesting a positive link between D1 receptor density and cognitive funct...
A recent study found that alcoholics experience a 'blunted' cortisol response after undergoing stressful tasks, which can lead to memory impairments. The researchers also discovered that the number of alcohol withdrawals is a strong predictor of memory deficits, but not problem-solving ability.
Chicago researchers awarded $9 million NIH grant to investigate the impact of lifestyle experiences on cognitive function and Alzheimer's disease. The study aims to understand how cognitively stimulating activities can increase neural reserve and reduce the likelihood of memory loss and other clinical signs of Alzheimer's.
Researchers found that cardiopulmonary bypass surgery can cause impaired memory and attention, which persist beyond the first couple of weeks. The study suggests that brain systems supporting attention may be particularly vulnerable during major surgeries.
A study found that participants who watched TV programs with sex or violence had impaired memory for advertised products compared to those who watched neutral programs. The results suggest that sex and violence can impair commercial memory, potentially deterring advertisers from sponsoring such content.
A study of Melbourne women found a decline in sexual interest, arousal, and frequency during menopause, with estradiol levels plummeting. Relationship factors, not hormonal changes, have the greatest impact on sexual response.
The study suggests that objects are recalled by uniting different brain regions, with the thalamus regulating electrical rhythms to connect these areas. This theory may help explain why some memories are clear while others are fuzzy.
A Brazilian study found that anticonvulsant therapy can lead to cognitive disabilities in epileptic children, affecting their ability to recall information. The research suggests a need for cooperation between physicians and educators to develop strategies to mitigate these effects.
Researchers at the University of South Florida found that individuals with the E4 type of apolipoprotein E (APOE) gene experience worse recovery of general memory function after brain injury. The study, which genotyped 110 head-injured patients, suggests common cellular responses in both traumatic brain injury and Alzheimer's disease.
Researchers at Duke University Medical Center found a link between nerve cell changes and the apolipoprotein E4 gene. Those with the APOE4 gene experienced more rapid loss of nerve cell functioning, leading to accelerated brain aging. This study may lead to new understanding of age-related memory loss and potentially sharper brains.
The study found that in older people with MCI, the brain produces more choline acetyltransferase, an enzyme important for memory and cognitive functions. This increase may be the brain's attempt to maintain normal function as neurons die.
A study by the University of Rochester Medical Center found that people with Alzheimer's disease struggle to perceive their own motion while driving, leading to increased risk of getting lost. The researchers tested 26 elderly patients with Alzheimer's and found they had difficulty judging their location on the road.
A new study found that Vietnam veterans with greater intellectual resources were significantly less likely to develop PTSD, and had less-severe symptoms if they did. The study suggests that verbal skills may help soldiers process their experience and establish social support networks.
Researchers have developed a non-invasive method to visualize brain lesions indicative of Alzheimer's disease in living patients using FDDNP and PET scans. This breakthrough will enable doctors to monitor disease progression and test new treatments more effectively.
A new study published in Nature reveals that increased activity in one brain system is associated with decreased activity in another during learning of a simple skill. The findings suggest new strategies for dealing with learning disorders and diagnosing Alzheimer's disease, as well as a better understanding of brain plasticity.
Scientists from Johns Hopkins School of Medicine and Pharmacia have found that mice engineered to produce human COX-2 protein develop age-related memory loss, mirroring problems seen in Alzheimer's disease. The study suggests targeting the protein could prevent neurological diseases.
A study of African-American residents aged 65 and older found that 23% had cognitive impairment without dementia, with rates increasing with age. The majority of cases lacked a medical cause, suggesting potential transient nature
A recent study published in American Journal of Clinical Nutrition found that energy consumption from carbohydrates, proteins, and fats enhances memory performance in healthy elderly individuals. The researchers discovered that fat improved attention while protein enhanced recall over time.
A new study using brain PET scans identifies metabolic changes in older adults that may indicate an increased risk of Alzheimer's disease. Researchers hope to develop a diagnostic tool to identify individuals at risk for the disease, allowing them to take preventive measures.
A study of 350 men and women found that mental aging begins in the 20s with continuous declines in processing power. By mid-60s, people may notice a decline in everyday activities. An increase in experience and knowledge can compensate for losses until age 50.
Indiana University Professor David Shiffrin has been awarded the $100,000 Rumelhart Prize for his work on human memory and cognition. His findings have had a significant impact on the field of psychology, with many cited works continuing to influence research.
A study found that lead exposure on the job can cause progressive declines in memory and learning abilities nearly two decades later. The effects of lead were seen even after exposure had stopped, suggesting a progressive impact on the brain.
Dr. Sherwin's research suggests that estrogen replacement therapy prevents some of the decline in verbal memory and ability to learn new material in postmenopausal women. This effect has been observed even in women who underwent surgical removal of their ovaries, which led to a sudden drop in estrogen levels.
Researchers used fMRI to probe the roots of a longstanding hypothesis in memory research. They found that recalling sensory-specific experiences activates brain regions responsible for processing those experiences. However, they also discovered that high-level perception areas are selectively reactivated during remembering, suggesting ...
Researchers found that attempting to control reactions to emotional events weakens memory, but reappraisal strategies have no such impact. The study suggests that expressive suppression, which involves continually monitoring and correcting oneself, consumes cognitive resources and reduces accuracy of event details.
A UC Davis study identifies brain systems affected in stroke patients with memory loss, distinguishing them from those affected by Alzheimer's disease. This distinction enables physicians to treat root causes of memory loss, such as high blood pressure or diabetes, and prevent strokes.
Researchers have successfully synthesized a highly potent memory-enhancing compound by joining two fragments of the Huperzine A molecule with a molecular tether. This simplified fragment can be easily produced from cheap, commercially available chemicals and has been shown to improve memory in animal tests.
Researchers found that long-term memories become labile every time they are retrieved, making them susceptible to alteration or disruption. The process of reconsolidation, which involves the generation of new proteins, is necessary to store long-term memories without retrieval.
Researchers found that individuals with autism spectrum disorder (ASD) performed better on a 'false-memory' test due to their impaired ability to use context. This improvement enabled them to recognize words that had been on a word list, while non-autistic subjects struggled with false memories. The study suggests that high-functioning...
A study by Dr. David Bennett found that many people with mild cognitive impairment exhibit Alzheimer's disease pathology, indicating a larger public health problem than previously thought. The research suggests increased funding for clinical care and research is needed to combat the disease effectively.
Researchers at Northwestern University have discovered that the growth-associated protein GAP-43 enhances learning and memory in the mammalian brain when overexpressed in a phosphorylatable form. This finding could lead to new treatments for memory loss and learning disorders.
Researchers found that higher doses of electroconvulsive therapy (ECT) were more effective in relieving depression, with 66.7% of patients experiencing relief compared to 38.9% on lower doses. However, the high-dose group also experienced temporary memory disturbances and longer recovery times.
A new study suggests that ginkgo extract may help protect the brain against stroke damage by reducing the extent of brain damage caused by free radicals. However, more work is needed to determine the proper dose and ensure its safety for humans at risk for stroke due to potential blood-thinning risks.
A new study by the Gladstone Institute of Neurological Disease and UCSF team found that apoE3 can inhibit memory problems associated with Alzheimer's disease, while apoE4 cannot. This discovery could lead to the development of new drugs simulating apoE3's protective quality.