Articles tagged with Memory Formation
Researchers have identified a key role for a protein called RyR2 in the development of long-term changes in brain connectivity associated with learning, memory, and addiction. By upregulating RyR2, nicotine can trigger the formation of new connections in the brain, leading to addictive behavior.
Researchers have identified a new gene required for memory formation in Drosophila, which may have similar functions in humans. The discovery sheds light on neurological disorders such as Alzheimer's disease and could lead to new insights into cognitive enhancement.
Researchers at Scripps Research Institute have uncovered a critical role for myosin II in long-term memory formation. Myosin II links together key processes, including signal transmission and synaptic plasticity, to solidify neuronal communication.
Researchers found that predator scent enhanced the ability of pond snails to form memory following training, while overcrowding and reduced calcium had a blocking effect. The scientists believe that the ability to remember unfamiliar environments, new predators and food sources is vital to the survival of the pond snail in the wild.
A new study led by the University of Leicester has revealed the mechanism by which memories are formed, highlighting the importance of the M3-muscarinic receptor in this process. The research, funded by the Wellcome Trust, holds potential to impact drug design for treating Alzheimer's disease.
Researchers discovered that methamphetamine enhances memory in pond snails, allowing them to recall learned behaviors despite being immersed in de-oxygenated water. This finding may provide insights into the mechanisms of human addiction and how memories are formed.
Research from neuroscientist Samuel Weiss shows that paternal mice physically interact with their babies grow new brain cells and form lasting memories of their babies. The study demonstrates a positive feedback loop between social interactions and healthy brains.
Researchers at UAB have made a breakthrough in understanding age-related memory loss, with histone deacetylase inhibitors showing great promise in both normal age-related decline and Alzheimer's disease. The findings provide important proof-of-principal for potential therapeutic interventions to improve quality of life in the aged.
Research reveals that sleep triggers cellular changes that promote memory formation, involving the NMDAR molecule. The brain undergoes significant reorganization during sleep to strengthen neural connections.
Researchers found that forgetting is an active process to remove memory, involving a molecular pathway including small protein Rac. Forgetting helps new information come in by removing old memories.
Researchers found that mice create 'knots' – preferred places with high path tortuosity – during exploration, which enhance their visual scene interpretation, memory of the place, and provide multiple views. This study contributes to understanding how animals map environments and accomplish goals.
Researchers will investigate protein expression in synapses to understand long-term and plastic memories, potentially revealing insights into post-traumatic syndrome and Alzheimer's disease. The €1.6 million grant will support international collaboration between Israeli and German institutions.
MCG scientists decoded memory-forming brain cell conversations using new technology and computational methods. The breakthrough enables researchers to identify the components of a memory and its retrieval at the network level, potentially pinpointing flawed memory formation stages.
Researchers at Karolinska Institutet have discovered a mechanism that controls the brain's ability to create lasting memories. The study found that signalling via the nogo receptor 1 plays a key part in this process, enabling the conversion of short-term memories into long-term ones.
A new study reveals that strong memories, such as those of a first love or a traumatic event, are formed through the activation of Protein Kinase C (PKC) by norepinephrine in the brain. This process creates stronger connections between nerve cells, leading to long-lasting memories.
Researchers have discovered that actin reorganization in two stages is controlled by different pathways, making it easy to encode new memories but hard to hold onto them. The Rho-ROCK pathway initiates cytoskeletal changes, while the Rac-PAK pathway solidifies them, leading to heightened synapse sensitivity and memory persistence.
A study by McGill University researchers has captured an image of a mechanism underlying long-term memory formation. New proteins are made locally at the synapse, increasing synaptic strength and reinforcing memories.
Researchers have discovered that calcium modulation affects long-term memory specifically while leaving learning and short-term memory intact. The study found that increased calcium levels during learning led to stronger responses to olfactory stimuli associated with food, indicating improved memory performance.
Research by Caltech scientists shows that theta oscillations sweep across the hippocampus as traveling waves, not a synchronized pulse. This finding challenges long-held assumptions about spatial information representation in rat brains and has significant implications for understanding memory formation and transmission.
Researchers found that historically-defined autobiographical periods exist, but their formation depends on the intensity and novelty of public events. Public events like wars and natural disasters can categorize personal memories as 'emotionally charged' or 'epoch-defining', causing them to become entwined with history.
A study by Nicole Lauzon and Dr. Steven Laviolette found specific receptors in the brain can control emotional significance and memory formation for traumatic events, offering new therapeutic treatments for psychiatric disorders like Schizophrenia and PTSD.
A recent Penn study showed that sleep strengthens neural connections in the brain, leading to improved memory formation. The research discovered that a key molecule called NMDAR plays a crucial role in this process, allowing calcium ions to flow into cells and trigger enzymes that strengthen connections during sleep.
A Weill Cornell Medical College study reveals that proBDNF, a neural growth factor, is present during the perinatal period when brain circuitry and memory-encoding regions are refined. The research provides new insights into how the brain is wired and how this wiring is refined, particularly during developmental stages.
Researchers at Northwestern University have discovered a new cellular mechanism that requires both types of neuronal metabotropic receptors to produce biochemical changes, increasing neuron firing and strengthening signals to other brain regions.
Dr. Mauro Costa-Mattioli has discovered a type of molecular switch in mice that determines whether a long-term memory is formed from an experience, improving spatial memory and synaptic connections. His research holds hope for developing new therapies for age-related memory loss and Alzheimer's Disease.
A study by Duke University Medical Center reveals that strong emotions and scents create lasting memories even when we're asleep. The researchers found that noradrenaline and odor cues are essential for memory formation, leading to changes in behavior upon waking.
Researchers found that beta-catenin plays a crucial role in solidifying fear memories in the brains of adult animals. The protein acts like a Velcro strap, fastening cells' internal skeletons to proteins on their external membranes.
Research reveals that as we age, our brains struggle to ignore irrelevant information and process information rapidly, leading to decreased memory formation. This breakdown occurs early in visual processing and persists despite attempts to suppress extraneous information.
Scientists at Cold Spring Harbor Laboratory discovered that protein Pum helps build memories by selectively altering individual synapses in fruit flies. The study, published in PLOS Computational Biology, used computational analysis to predict the interactions of Pum with other genes and confirmed its role in memory formation.
A study at NYU and Weizmann Institute of Science identified brain activation patterns linked to long-term memories by simulating everyday experiences. The researchers found activity in new areas, including the temporal pole, STG, mPFC, and TPJ, which have been implicated in social cognition.
A University of Houston team found that melatonin inhibits memory formation in zebrafish during nighttime. Removing the melatonin-producing gland allowed fish to form memories at high levels even at night.
Researchers at the University of Pennsylvania have created a new form of computer memory using nanowires that can store data for 100,000 years and retrieve it up to 1,000 times faster than current technology. The device uses less power and space than existing memory technologies.
Scientists found that long-term memories require a miniature molecular machine to maintain, which must be constantly active. Jamming this 'machine' can briefly erase memories, suggesting potential future treatments for memory problems.
A new MIT study finds that mature brains process and retain rich, contextual memories better than younger brains. Adults demonstrated a more developed prefrontal cortex leading to enhanced contextual memory formation.
A new theory proposes that learning skills, such as flying, accelerates the evolution of innate abilities in birds by creating a latent memory that reduces the need for future generations to learn. This is achieved through the use of distributed representations in neural networks, which allows for faster evolution of adaptive behaviors.
Researchers challenge long-held assumption that new protein synthesis is necessary for recording memories in long-term storage. Brain chemistry changes caused by protein synthesis inhibitors can disrupt memory formation instead.
Researchers have made a breakthrough in understanding memory by capturing the physical substrate of newly encoded memories. The study shows that synaptic connections change shape when rats learn to navigate a new environment, and this change is essential for stable memory formation.
Researchers at MIT's Picower Institute have discovered a molecular mechanism that governs the formation of fears stemming from traumatic events. Inhibiting a kinase called Cdk5 facilitates the extinction of fear, while increased activity persists fear learned in a particular context.
Researchers have developed unique images of physical changes in brain cells associated with memory, uncovering clues about memory loss linked to cognitive disorders. The study also reveals that LTP deficiencies accompany the memory loss seen during the early stages of Huntington's disease and can be fully reversed through treatment.
Researchers have identified a specific region in the frontal cortex as key to recording and learning social information. This discovery may improve understanding of mechanisms behind mental disorders affecting social skills, such as schizophrenia and autism.
A study by Thomas Foster at the University of Florida found that rats become forgetful due to an imbalance in brain cell communication. The researchers discovered that 'long-term depression' - a normal process that helps sculpt memory - can lead to rapid forgetting when it occurs excessively.
Research by Graham R. Huesmann and David F. Clayton reveals that activated caspase-3 protein is essential for memory storage and forms short-lived, localized synaptic processes. The findings provide direct evidence of a change in caspase-3's availability during memory formation.
Researchers have found that proteins essential for brain growth during development are equally important for forming long-term memories. Growth factors like BDNF play a critical role in retaining long-term memory by binding to specific receptors in the brain, and their absence can block this process.
Researchers found that anticipation can fire up two brain regions - amygdala and hippocampus - even before the event occurs, strengthening memories of disturbing events. This study has important implications for treating conditions like PTSD and social anxiety.
Researchers used functional magnetic resonance imaging to study how brain regions involved in reward processing interact with memory. They found that cues to high-reward scenes activated both the mesolimbic region and the hippocampus, leading to better memory performance for high-value scenes.
A memory trace is formed in a pair of neurons called the dorsal pair medial neurons, but only 30 minutes after the fact and through the mediation of a gene called amnesiac. The change can last about two hours, challenging the common-held precept that memories are stored in the same place.
A study at Fred Hutchinson Cancer Center identified the neuroD2 gene as a potential controller of risk-taking behavior and emotional memory in humans. Mice with one copy of the gene showed impaired ability to form emotional memories and conditioned fear, similar to humans who have varying levels of risk-taking tendencies.
Researchers have successfully cloned meat and milk from bulls and cows, showing no significant differences in quality compared to naturally bred animals. Meanwhile, a study suggests that early humans may have driven elephant extinctions on multiple continents.
University of Houston professor Arnold Eskin's research suggests the biological clock regulates long-term memory formation, with neural circuits shutting down at night. His studies on Aplysia reveal that circadian rhythms influence memory formation, but not short-term memory.
Researchers found that brain activity in the hippocampus and perirhinal cortex predicts accurate or false memories. Weak prefrontal cortex activity during misinformation phase indicates poorly placed details, creating false memories.
A study by Patricia West and colleagues found that writing stories about paintings boosts writer's preference for a painting. Stories focusing on the author also show improved recall and enjoyment of the task. The authors argue that this effect applies to various consumer goods, such as clothing and family vacations.
A new protein called mBDNF has been found to play a crucial role in forming long-term memories. The discovery opens up possibilities for studying the protein in people with disorders of learning and memory, as well as developing new medications to compensate for these problems.
A study published in Psychological Science used MRI technology to investigate how people form false memories. The researchers found that brain activity in specific areas, such as the precuneus and right inferior parietal cortex, was greater for words that were later falsely remembered as having been presented with photos. This suggests...
Researchers found that suppressing CBP function in adult rodents impaired long-term memory, but administering a histone deacetylase inhibitor corrected this defect. This suggests remodeling of chromatin is essential for learning and memory, and may offer new treatment options for cognitive disorders.
A new study found that the brain's amygdala interacts with memory-related brain regions during emotional memory formation, contributing to its emotional resonance. The researchers discovered a significant correlation between activity in emotion- and memory-related brain regions during emotional memory formation.
Scientists have developed fruit flies with fluorescent genes to study memory formation, discovering that a specific set of neurons, called projection neurons, show increased active connections after learning. The new synaptic activity disappeared within minutes but the flies continued to avoid the odor they associated with the shock.
A recent study by researchers at the University of North Carolina at Chapel Hill found that a lack of choline during pregnancy can lead to reduced brain cell formation and impaired memory in children. The scientists discovered that choline plays a crucial role in regulating stem cell division, which is essential for brain development.
Researchers discovered that the radish gene encodes a phospholipase-A2 enzyme, which plays a crucial role in anesthesia-resistant memory. The study found this enzyme is also involved in memory formation in chickens and rodents, suggesting a conserved mechanism across animal phyla.
The study reveals a direct activational signal from the synapse to the protein synthesis machinery, enabling neurons to boost protein production rapidly during long-term memory formation and synaptic strengthening. This discovery has significant implications for understanding psychiatric and neurologic diseases, potentially leading to ...
A team of researchers has identified an enzyme, protein kinase C, that may play a crucial role in turning fleeting experiences into lasting memories. The study found that this enzyme helps to activate genes that express proteins involved in forming long-term memories.