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Science News Archive December 2000 - Page 5


Page 5 of 6

Gene believed linked to serious kidney disease

A Yale researcher has found a gene believed to be linked to autosomal recessive polycystic kidney disease (ARPKD), a condition affecting one in 10,000 children. The study suggests that primary cilia, hair-like projections lining the kidneys' ducts and tubules, play a crucial role in the development of ARPKD.

Hepatitis C drug overwhelms virus with flood of mutations - surprising mechanism may improve anti-viral treatments, UCSF study finds

A recent study from the University of California, San Francisco has discovered a novel mechanism by which the drug ribavirin kills viruses by generating excess mutations that overwhelm the virus. This unexpected finding may lead to the development of more effective anti-viral treatments for hepatitis C patients.

SourceUniversity of California - San Francisco·JournalNature Medicine·DateDec 7, 2000

PBBs in fire retardant associated with early menstruation in Michigan girls whose mothers were exposed in 1973

A 2000 study found that daughters of mothers exposed to the chemical polybrominated biphenyl (PBB) in contaminated Michigan feed experienced earlier onset of menstruation and pubic hair growth. The study, funded by NIH/NIEHS, linked high PBB exposure to an average age of first menstruation before 12 years.

Screensavers of the world, unite!

Distributed computing is revolutionizing the way scientists solve complex computational problems, enabling breakthroughs in astronomy and biology. The Stanford-led project Folding@home has taken off, with over 10,000 volunteers contributing their home computers to protein folding research.

SourceStanford University·JournalScience·DateDec 7, 2000

DNA research reveals new bird species in Colorado

Researchers at U.S. Geological Survey and University of Denver have identified a new bird species, the Gunnison sage-grouse, through DNA analysis and genetic research. The study confirms the species' distinctiveness from the Greater sage-grouse and highlights concerns about its low genetic diversity and population decline.

SourceU.S. Geological Survey·JournalThe Wilson Bulletin·DateDec 6, 2000

How do I love whales? Let me count the ways

A Texas A&M University research team is counting Bowhead whales in the Okhotsk Sea to estimate their population size and understand the impact on the ecosystem. By using photo identification and genetic testing, researchers hope to gather information on the whales' feeding behavior and determine if their food supply is dwindling.

Team identifies first drug therapy for rare, precancerous stomach illness

Researchers at Vanderbilt University Medical Center have identified a new drug therapy that appears to be effective in reversing symptoms of Ménétrier's disease, a rare and premalignant stomach disorder. The treatment, which blocks activation of the EGF receptor, showed promising results in a patient with severe vomiting and protein loss.

SourceVanderbilt University Medical Center·JournalNew England Journal of Medicine·DateDec 6, 2000

Tubal sterilization poses no greater risk of menstrual abnormalities, study finds

A comprehensive study found that women who underwent tubal sterilization have no greater risk of menstrual abnormalities than those who did not. However, the study also reported a secondary finding of reduced menstrual pain and bleeding among sterilized women, which may be due to chance or unknown factors.

Obesity impacts quality of life

A study analyzing health data from nearly 3,000 patients found that obesity is associated with lower physical functioning levels and worse perceptions of health. Patients with higher BMI values were also limited in basic activities due to their weight, according to lead author David A. Katz.

SourceCenter for Advancing Health·JournalJournal of General Internal Medicine·DateDec 5, 2000

Breast-cancer risk related to insulin-resistance indicators, elevated levels of sex hormones, UB study shows

A new UB study reveals a significant association between breast cancer risk and physical characteristics of insulin resistance, including abdominal fat distribution and higher-than-normal male and female sex hormones. Women with increased waist-to-hip ratio and oily skin are at greater risk of developing breast cancer.

SourceUniversity at Buffalo·JournalCancer Causes & Control·DateDec 4, 2000

'Translocation' surgery yields unprecedented results

A new operation developed at Johns Hopkins improves vision for nearly half of the first 100 patients treated with early-stage macular degeneration. Six months after surgery, 48% of patients could read an additional two lines on a standard eye chart or had vision of 20/100 or better, enough to legally drive in Maryland.

SourceJohns Hopkins Medicine·JournalAmerican Journal of Ophthalmology·DateDec 4, 2000

Researchers reveal insidious role of a 'serpin' in Alzheimer's Disease

A team of researchers found that the protein alpha1-antichymotrypsin doubles the accumulation of Alzheimer's disease-associated amyloid plaque in mice brains, indicating a potential therapeutic target. The study suggests that reducing or inhibiting this protein's activity could help prevent plaque formation and brain damage.

SourceUniversity of California - San Francisco·JournalAmerican Journal Of Pathology·DateDec 4, 2000

Game of life allows all mating strategies

A study by Cornell University researchers found that each mating strategy in side-blotched lizards has its advantages and vulnerabilities, allowing them to coexist and perpetuate. The aggressive orange-throated males, loyal blue-throated males, and sneaky yellow-throated males all have a reasonable chance of reproductive success.

SourceCornell University·JournalProceedings of the National Academy of Sciences·DateDec 4, 2000